الصفحة 19
الصفحة 19
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Clinical microbiology made ridiculously simple

Is a brief, clear, thorough, and updated approach to clinical microbiology, brimming with mnemonics, humor, summary charts, and illustrations. Topics include Ebola, AIDS, flesh-eating bacteria, mad cow disease, hantavirus, anthrax, smallpox, and tuberculosis; the latest antibiotics; pandemic flu, including H7N9; SARS-like coronavirus; hepatitis C treatment options; HIV diagnostics and approved HIV meds; Zika virus; measles; and a new chapter on the latest emerging infectious diseases and drug-resistant bacteria. The major update to this book is the addition of a new chapter on the SARS-COV-2 virus and COVID-19 disease, which delves into the nature of the virus such as infectivity within the body, transmission between individuals, timeline of infectivity, symptoms, risk factors, therapeutics, and vaccines approved for use.

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Climatic Changes and Water Resources in the Middle East and North Africa

The subject is described and discussed in three main chapters and different case studies.All topics in this book are complimentary and contribute to a comprehensive understanding of the interactions between global climate change, world water cycle and water resources. A valuable and meaningful interdisciplinary mixture of topics is combined in this book.

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Climate-Smart Food

This book asks just how climate-smart our food really is. It follows an average day's worth of food and drink to see where it comes from, how far it travels, and the carbon price we all pay for it. From our breakfast tea and toast, through breaktime chocolate bar, to take-away supper, Dave Reay explores the weather extremes the world’s farmers are already dealing with, and what new threats climate change will bring. Readers will encounter heat waves and hurricanes, wildfires and deadly toxins, as well as some truly climate-smart solutions. In every case there are responses that could cut emissions while boosting resilience and livelihoods. Ultimately we are all in this together, our decisions on what food we buy and how we consume it send life-changing ripples right through the global web that is our food supply.

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Climate change : Environment and history of the Near East

When the ?rst edition of this book was published in 2004, the following year 2005 has happened to have been the warmest year since 1880, when the ?rst reliable worldwide instrumental records came into existance. Claiming no li- age between the publication of our book and the temperature record, yet this record demonstrates the trend of increase in the global surface temperatures during thepast20years,reinforcedbyevidenceofriseofatmosphere’sand oceans’ temperatures, and increased melting of ice and snow in the arctic and antarctic regions as well as on mountain tops. All these observations are par- leled by the increase in the quantity of heat trapping gases in the atmosphere, causing most probably, the global greenhouse effect. In order to try and predict, what might be the impact of this effect on the on the natural and human environments of the Near East, (Figs. 1–1d) the authors adopted the saying that the past is the key for the future. The practical conclusion of this principle says that the acquiring knowledge of the impact of past climate changes on the nature and human societies, may allow conclusions with regard to future possible impact of climate changes. By correlating proxy data of all types, paleo-sea and lake levels, paleo-hydrology, pollen pro?les, environmental isotopes as well as archaeological and historical documents, the authors tried to collect as much as possible of this knowledge.

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Click chemistry

In chemical synthesis, click chemistry is a class of simple atomic economy reactions commonly used to join two selected molecular entities. Click chemistry is not one specific reaction, but describes a method for generating products that follow examples in nature, which also generates substances by joining small modular units. In many applications, click interactions that join a biomolecule and a reporter molecule. Click chemistry is not limited to biological conditions: the concept of a 'click' reaction has been used in protein chemistry, pharmacokinetics, and many biomimetic applications. However, they have been made remarkably useful in the discovery, localization and qualification of biomolecules.

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Chromatin and Disease

It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics.

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Chemistry of natural products : phytochemistry and pharmacognosy of medicinal plants

Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques.

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Charge Migration in DNA : Perspectives from Physics, Chemistry, and Biology

Charge migration through DNA has been the focus of considerable interest in recent years. A deeper understanding of the nature of charge transfer and transport along the double helix is important in fields as diverse as physics, chemistry and nanotechnology. It has also important implications in biology, in particular in DNA damage and repair. This book presents contributions from an international team of researchers active in this field.

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Chaos, Nonlinearity, Complexity : The Dynamical Paradigm of Nature

This carefully edited book presents a focused debate on the mathematics and physics of chaos, nonlinearity and complexity in nature. It explores the role of non-extensive statistical mechanics in non-equilibrium thermodynamics, and presents an overview of the strong nonlinearity of chaos and complexity in natural systems that draws on the relevant mathematics from topology, measure-theory, inverse and ill-posed problems, set-valued analysis, and nonlinear functional analysis. It presents a self-contained scientific theory of complexity and complex systems as the steady state of non-equilibrium systems, denoting a homeostatic dynamic equilibrium between stabilizing order and destabilizing disorder.

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Changing Forests : Collective Action, Common Property, and Coffee in Honduras

It merges political ecology, collective-action theories, and institutional analysis to study how the people and forests have changed through socioeconomic and political transitions. It studies the complex, often contradictory relationships between the people and their natural resources to understand why forest cover endures."Changing Forests" therefore encompasses three broad phases: (1) the premodern period, which considers historic perturbations in western Honduras from the period of colonialism into the middle of the twentieth century; (2) the period of state-led logging and intervention in La Campa, which caused major degradation in forest cover; and (3) the recent period in which export coffee production transformed property rights, and people’s perceptions of the forest gained new conservationist and economic dimensions. Each phase entails perspectives and experiences that influenced human use of forests, and shaped subsequent transformations.

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Chance : The life of games and the game of life

With its many easy-to-follow mathematical examples, this book takes the reader on an almost chronological trip through the fascinating and amazing laws of chance, omnipresent in the natural world and in our daily lives. Along the route many fascinating topics are discussed, such as: challenging probability paradoxes; "paranormal" coincidences; game odds; causes and effects; interpretation of opinion polls; winning chances as a game proceeds; the nature of randomness; entropy and randomness; randomness in life; algorithmic complexity and the undecidability of randomness; possibilities and limitations of learning the laws of a Universe immersed in chance events. This charming book will inform and entertain the scientist and non-scientist alike.

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Ceramic and Glass Materials : Structure, Properties and Processing

Ceramic and Glass Materials: Structure, Properties and Processing is a concise and comprehensive guide to the key ceramic and glass materials used in modern technology. Each chapter focuses on the structure-property relationships for these important materials and expands the reader’s understanding of their nature by simultaneously discussing the technology of their processing methods. In each case, the resulting understanding of the contemporary applications of the materials provides insights as to their future roles in twenty first century engineering and technology. Organized to be a practical and comprehensive resource, each chapter is dedicated to a specific material such as: alumina, mullite, sillimanite minerals, aluminates, quartz and silicas, refractory oxides, clays, concrete and cement, lead compounds, and zirconia.

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Cellulose : Molecular and Structural Biology : Selected Articles on the Synthesis, Structure, and Applications of Cellulose

Cellulose: Molecular and Structural Biology is an up-to-date treatise on the most advanced and provocative research into the biosynthesis, structure, and applications of nature’s most abundant macromolecule and renewable resource, cellulose.Molecular, biochemical, and evolutionary aspects of cellulose biosynthesis are reviewed in a variety of living organisms, including cyanobacteria, eubacteria, (Acetobacter, Salmonella, and E. coli), vascular plants (including Arabidopsis, forest trees, and maize), and tunicates.

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Cellular Genetic Algorithms

CELLULAR GENETIC ALGORITHMS defines a new class of optimization algorithms based on the concepts of structured populations and Genetic Algorithms (GAs). The authors explain and demonstrate the validity of these cellular genetic algorithms throughout the book. This class of genetic algorithms is shown to produce impressive results on a whole range of domains, including complex problems that are epistatic, multi-modal, deceptive, discrete, continuous, multi-objective, and random in nature. The focus of this book is twofold. On the one hand, the authors present new algorithmic models and extensions to the basic class of Cellular GAs in order to tackle complex problems more efficiently. On the other hand, practical real world tasks are successfully faced by applying Cellular GA methodologies to produce workable solutions of real-world applications.

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Cell-Cell Channels

The biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. This concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap­ parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel­ ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc­ tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.

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Cell Adhesion and Cytoskeletal Molecules in Metastasis

In this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume; both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.

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Cathodic Arcs : From Fractal Spots to Energetic Condensation

Cathodic Arcs: From Fractal Spots to Energetic Condensation is the first book in over a decade dedicated to the physics and technology of cathodic arcs. It includes a detailed account of arc history, a textbook-like introduction to cathode phenomena, and some basic physics of expanding plasmas; it deals with the infamous macroparticle issue and describes a host of practical plasma filter solutions. In contrast to previous books on cathodic arcs, the focus is on the relation of arc plasmas and their properties to surface modification and thin film deposition. The book contains sections on basic plasma physics and thin film materials science. It also deals with practical issues of coatings such as stress control and the often-underrated issue of the coating’s color. By stressing the fractal nature of cathode spots, the theme of fluctuations can be found throughout the book: fluctuations affect all plasma properties and thereby have consequences for plasma-based surface modifications and film growth.

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Cassini at Saturn- Huygens Results

Cassini At Saturn – Huygens Results brings the story of the Cassini-Huygens mission and their joint exploration of the Saturnian system right up to date. Cassini entered orbit around Saturn June 2004 so this update includes 8 months of scientific data available for review, including the most spectacular images of Saturn, its rings and satellites ever obtained by a space mission. As the Cassini spacecraft approached its destination in spring 2004, the quality of the images already being returned by the spacecraft clearly demonstrated the spectacular nature of the close-range views that will be obtained. The book contains a 16-page colour section, comprising a carefully chosen selection of the most stunning images to be released during the spacecraft’s initial period of operation.

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Case-Based Approximate Reasoning

Case-based reasoning (CBR) has received a great deal of attention in recent years and has established itself as a core methodology in the field of artificial intelligence. The key idea of CBR is to tackle new problems by referring to similar problems that have already been solved in the past. More precisely, CBR proceeds from individual experiences in the form of cases. The generalization beyond these experiences typically relies on a kind of regularity assumption demanding that 'similar problems have similar solutions'. Making use of different frameworks of approximate reasoning and reasoning under uncertainty, notably probabilistic and fuzzy set-based techniques, this book develops formal models of the above inference principle, which is fundamental to CBR. The case-based approximate reasoning methods thus obtained especially emphasize the heuristic nature of case-based inference and aspects of uncertainty in CBR. This way, the book contributes to a solid foundation of CBR which is grounded on formal concepts and techniques from the aforementioned fields. Besides, it establishes interesting relationships between CBR and approximate reasoning, which not only cast new light on existing methods but also enhance the development of novel approaches and hybrid systems.

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Carpooling optimization

The aim of this project is to collect and use the GPS data from mobile devices to get geolocations and translate this data to paths, starting points and destinations to detect patterns out of each individual trajectories that have stochastic nature on the close sight and find representations of those patterns. The second half of the artificial intelligence algorithms has the task of finding the optimal matching of the patterns that were detected in a computation efficient way that achieve the most efficient way of transportation.

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