الصفحة 13
الصفحة 13
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Bioinformatics and Computational Biology Solutions Using R and Bioconductor

Bioconductor is a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology. Bioconductor is rooted in the open source statistical computing environment R. This volume's coverage is broad and ranges across most of the key capabilities of the Bioconductor project, including: Importation and preprocessing of high-throughput data from microarray, proteomic, and flow cytometry platforms / Curation and delivery of biological metadata for use in statistical modeling and interpretation. / Statistical analysis of high-throughput data, including machine learning and visualization,modeling and visualization of graphs and networks. This book is a dynamic document. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.

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Bioeconomic modelling and valuation of exploited marine ecosystems

This book offers an environmental-economic analysis of exploited ecosystems with a clear policy orientation. The study tries to move beyond traditional economic fishery analysis in two respects. First, several theoretical and numerical models are offered that combine economic and ecological descriptions of fisheries. These models give special attention to spatial processes as well as to combining exploitation and conservation objectives. Second, valuation and stakeholder concerns are addressed in empirical analyses employing both qualitative and quantitative approaches. The latter is done by using advanced methods of monetary valuation. In addition, the first part of the book presents short, introductory overviews of integrated assessment, economic modeling of fishery management, and incorporating uncertainty in fisheries analysis.

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Bioactive Heterocycles IV

This volume contains nine more contributions from expert researchers of the?eld, providing readers with in depth and current research results regarding therespective topics. In the?rst chapter, Flemming et al. review the chemistry, biosynthesis, metabolism and biological activities of tetrahydrocannabinol and its deri- tives. Hansch and Verma contribute to the quantitative structure-activity re- tionship (QSAR) analysis of heterocyclic topoisomerase I and II inhibitors. These inhibitors, knowntoinhibit either enzyme, actasantitumoragentsand are currently used in chemotherapy and in clinicaltrials. In the third chapter, Khan reviews some aspects of molecular modeling studies on biologically active alkaloids.

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Bifurcations, Instabilities, Degradation in Geomechanics

Leading international researchers and practitioners of bifurcations and instabilities in geomechanics debate the developments and applications which have occurred over the last few decades. The topics covered include modeling of bifurcation, structural failure of geomaterials and geostructures, advanced analytical, numerical and experimental techniques, and application and development of generalised continuum models etc. In addition analytical solutions, numerical methods, experimental techniques, and case histories are presented. Beside fundamental research findings, applications in geotechnical, petroleum, mining, and bulk materials engineering are emphasised.

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Benchmarking, Temporal Distribution, and Reconciliation Methods for Time Series

This book discusses the statistical methods most often applied for such adjustments, ranging from ad hoc procedures to regression-based models. The latter are emphasized, because of their clarity, ease of application, and superior results. Each topic is illustrated with many real case examples. In order to facilitate understanding of their properties and limitations of the methods discussed, a real data example, the Canada Total Retail Trade Series, is followed throughout the book.This book brings together the scattered literature on these topics and presents them using a consistent notation and a unifying view.

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Bayesian core : A practical approach to computational Bayesian statistics

This Bayesian modeling book provides an operational methodology for conducting Bayesian inference, rather than focusing on its theoretical justifications. Special attention is paid to the derivation of prior distributions in each case and specific reference solutions are given for each of the models.

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Bayesian computation with R : Introduces Bayesian modeling by use of computation using the R language

R's open source nature, free availability, and large number of contributor packages have made R the software of choice for many statisticians in education and industry. Bayesian Computation with R introduces Bayesian modeling by the use of computation using the R language.

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Battery management systems : Accurate state-of-charge indication for battery-powered applications

Builds further on the contents of the first volume in the Philips Research Book Series, Battery Management Systems - Design by Modelling. Since the subject of battery SoC indication requires a number of disciplines, this book covers all important disciplines starting from (electro)chemistry to understand battery behaviour, via mathematics to enable modelling of the observed battery behaviour and measurement science to enable accurate measurement of battery variables and assessment of the overall accuracy, to electrical engineering to enable an efficient implementation of the developed SoC indication system. It will therefore serve as an important source of information for any person working in engineering and involved in battery management.

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Basics of Aerothermodynamics

The discrete numerical methods of aerodynamics/aerothermodynamics permit now - what was twenty years ago not imaginable - the simulation of high speed flows past real flight vehicle configurations with thermo-chemical and viscous effects, the description of the latter being still handicapped by in sufficient flow-physics models.

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Average-Cost Control of Stochastic Manufacturing Systems

This book is concerned with hierarchical control of manufacturing systems under uncertainty. It focuses on system performance measured in long-run average cost criteria, exploring the relationship between control problems with a discounted cost and that with a long-run average cost in connection with hierarchical control. A new theory is articulated that shows that hierarchical decision making in the context of a goal-seeking manufacturing system can lead to a near optimization of its objective. The approach in the book considers manufacturing systems in which events occur at different time scales.

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Autonomous Navigation in Dynamic Environments

The purpose of this book is to address the challenging problem of Autonomous Navigation in Dynamic Environments, and to present new ideas and approaches in this newly emerging technical domain. The book surveys the state-of-the-art, discusses in detail various related challenging technical aspects, and addresses upcoming technologies in this field. The aim of the book is to establish a foundation for a broad class of mobile robot mapping and navigation methodologies for indoor, outdoor, and exploratory missions.Three main topics located on the cutting edge of the state of the art are addressed, from both the theoretical and technological point of views: Dynamic world understanding and modelling for safe navigation, Obstacle avoidance and motion planning in dynamic environments, and Human-robot physical interactions. Several models and approaches are proposed for solving problems such as Simultaneous Localization and Mapping (SLAM) in dynamic environments, Mobile obstacle detection and tracking, World state estimation and motion prediction, Safe navigation in dynamic environments, Motion planning in dynamic environments, Robust decision making under uncertainty, and Human-Robot physical interactions.

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Automotive Control Systems : For Engine, Driveline, and Vehicle

Reflecting the trend to optimization through integrative approaches for engine, driveline and vehicle control, this book enables control engineers to understand engine and vehicle models necessary for controller design and also introduces mechanical engineers to vehicle-specific signal processing and automatic control. The emphasis on measurement, comparisons between performance and modelling, and realistic examples derive from the authors’ industrial experience at Bosch and interactions within IFAC and SAE. The second edition offers new or expanded topics such as diesel-engine modelling, diagnosis and anti-jerking control, and vehicle modelling and parameter estimation. The book addresses professional engineers as well as students.

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Automatic Differentiation : Applications, Theory, and Implementations

This collection covers the state of the art in automatic differentiation theory and practice. Practitioners and students will learn about advances in automatic differentiation techniques and strategies for the implementation of robust and powerful tools. Computational scientists and engineers will benefit from the discussion of applications, which provide insight into effective strategies for using automatic differentiation for design optimization, sensitivity analysis, and uncertainty quantification.

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Auralization : Fundamentals of acoustics, modelling, simulation, algorithms and acoustic virtual reality

"Auralization" is the technique of creation and reproduction of sound on the basis of computer data. With this tool is it possible to predict the character of sound signals which are generated at the source and modified by reinforcement, propagation and transmission in systems such as rooms, buildings, vehicles or other technical devices. This book is organized as a comprehensive collection of the basics of sound and vibration, acoustic modelling, simulation, signal processing and audio reproduction. Implementations of the auralization technique are described using examples drawn from various fields in acoustic’s research and engineering, architecture, sound design and virtual reality.

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Atomistic modeling of materials failure

Atomistic Modeling of Materials Failure is an introduction to molecular and atomistic modeling techniques applied to solid deformation and fracture. Focusing on a variety of brittle, ductile and geometrically confined materials, this detailed overview includes computational methods at the atomic scale, and describes how these techniques can be used to model the dynamics of cracks, dislocations and other deformation mechanisms.

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Atmospheric Icing of Power Networks

Atmospheric ice takes a wide range of fascinating forms, all beautiful in their own ways but many posing severe risk to the security of overhead networks for electric power, communications and other systems. This book documents the fundamentals of atmospheric icing and surveys the state of the art in eight chapters, each written by a team of experienced and internationally renowned experts.

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Atmospheric and space flight dynamics : Modeling and simulation with MATLAB® and Simulink®

Modern aerospace vehicles, such as the space shuttle, other launch vehicles, and long-range ballistic missiles, do not discriminate between atmospheric and space flight. Most texts on flight dynamics, however, make this artificial distinction and therefore do not simultaneously cover aircraft and spacecraft. Bridging this gap in the literature, Atmospheric and Space Flight Dynamics is a unified presentation, demonstrating that the two disciplines have actually evolved from the same set of physical principles.Primarily useful as a textbook for advanced undergraduate and beginning graduate-level students, the work is also an excellent reference or self-study guide for researchers and practitioners in aerospace engineering, aviation, mechanical engineering, dynamics, astrodynamics, aeronautics, and astronautics.

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Atmospheric and Oceanic

This volume contains many original findings on mesoscale processes in atmospheric and oceanic systems through mathematical modeling, numerical simulations and field experiments. These scientific papers examine and provide the latest developments on a range of topics that include tropical cyclones/hurricanes, mesoscale variability and modeling, seasonal monsoons and land surface processes including atmospheric boundary layer. This volume will be useful as a reading material in graduate level courses dealing with mesoscale systems, weather, climate, monsoon variability and boundary layer.

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Astrophysical disks : Collective and stochastic phenomena

The book deals with collective and stochastic processes in astrophysical discs involving theory, observations, and the results of modelling. Among others, it examines the spiral-vortex structure in galactic and accretion disks , stochastic and ordered structures in the developed turbulence. It also describes sources of turbulence in the accretion disks, internal structure of disk in the vicinity of a black hole, numerical modelling of Be envelopes in binaries, gaseous disks in spiral galaxies with shock waves formation, observation of accretion disks in a binary system and mass distribution of luminous matter in disk galaxies.

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Assessment of climate change over the Indian Region : A report of the Ministry of Earth Sciences (MoES), Government of India

Discusses the impact of human-induced global climate change on the Indian subcontinent and regional monsoon, the adjoining Indian Ocean and the Himalayas. It also examines the regional climate change projections based on the climate models used by the IPCC Fifth Assessment Report (AR5) and national climate change modeling studies using the IITM Earth System Model (ESM) and CORDEX South Asia datasets

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