Lung biology and pathophysiology
The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics.
Biogeography, Time, and Place : Distributions, Barriers, and Islands
Biogeography considers the distribution of biological units over a wide range of scales. The units range from genotypes, populations and species to families and higher taxa. Processes can be local, such as the isolation on islands due to sea-level fluctuations, or large-scale tectonic processes that separates continents and creates oceans. In all processes time is an important factor and by combining data on recent patterns with paleontological data the understanding of the distribution of extant taxa can be improved. This volume focuses on speciation due to isolation in island-like settings, and the evolution of large-scale diversity as the result of origination, maintenance and extinction.
Managed Software Evolution
This open access book presents the outcomes of the “Design for Future – Managed Software Evolution” .The different lifecycles of software and hardware platforms lead to interoperability problems in such systems. Instead of separating the development, adaptation and evolution of software and its platforms, as well as aspects like operation, monitoring and maintenance, they should all be integrated into one overarching process. Accordingly, the book is split into three major parts, the first of which includes an introduction to the nature of software evolution, followed by an overview of the specific challenges and a general introduction to the case studies used in the project. The second part of the book consists of the main chapters on knowledge carrying software, and cover tacit knowledge in software evolution, continuous design decision support, model-based round-trip engineering for software product lines, performance analysis strategies, maintaining security in software evolution, learning from evolution for evolution, and formal verification of evolutionary changes. In turn, the last part of the book presents key findings and spin-offs. The individual chapters there describe various case studies, along with their benefits, deliverables and the respective lessons learned. An overview of future research topics rounds out the coverage.
Maintenance Theory of Reliability
The book provides a detailed introduction to maintenance policies, updates the reader on the current status of the field and indicates future directions. The reader will learn the theory of maintenance and how to apply models in practice.
Machine learning for cyber-physical systems: selected papers from the international conference ML4CPS 2023
Contains selected papers from the international conference ML4CPS – Machine Learning for Cyber-Physical Systems, which was held in Hamburg (Germany), from 29 to 31 March 2023. Cyber-physical systems are adaptive and learning: they analyze their environment and, based on observations, learn patterns, associations and predictive models. Typical applications are condition monitoring, predictive maintenance, image processing and diagnostics. Machine learning is the key technology for these developments.
Beginning Ubuntu Linux
Beginning Ubuntu Linux, the award–winning and best–selling Ubuntu book for beginners, is now in its third edition, presenting readers with an up–to–the–minute introduction to the world of Linux and the open source community. A detailed overview of Ubuntu's installation and configuration process encourages you to take the plunge and switch to Linux, and from there you'll learn how to wield total control over your newly installed operating system. Guided through the most commonly desired tasks such as printer configuration, listening to audio CDs and MP3s, watching movies, performing office and Internet–related tasks, as well as general system maintenance matters, authors Keir Thomas and Jaime Sicam will soon have you using and enjoying Ubuntu Linux and never looking back.
Adobe® Acrobat® and PDF for Architecture, Engineering, and Construction
Adobe® Acrobat® and PDF for Architecture, Engineering, and Construction is designed to appeal to the engineering mind. The book is a practical guide focusing on the applications of PDF in the solution of "engineering" problems which may arise in a number of disciplines from architecture to construction. Using real-world examples, the authors follow a project from design through build and long-term maintenance. As the sample project evolves, suitable Acrobat® tools and techniques are identified and brought into play at each stage, showing readers how to personalize the context and processes to meet their own project development and management needs.
Biomimetic restorative dentistry ; Vol.1 : Fundamentals and basic clinical procedures
Takes the science of esthetic dental reconstruction to a new level both clinically and academically, and it offers all that a clinician could wish for in terms of indications and the classic clinical steps for tooth preparation, laboratory and CAD/CAM procedures, adhesive luting procedures, and maintenance. But above all, what makes this book so unique is the biomimetic principle—as such, restoring or mimicking the biomechanical, structural, and esthetic integrity of teeth is paramount. The core of this book centers on the application of the biomimetic principle in the form of bonded restorations using composite resins and ceramics, covering indications, treatment planning, diagnosis, tooth preparation and impression, laboratory and CAD/CAM procedures, final delivery, follow-up, maintenance, and repair. Written by a true master and artist, this book will undoubtedly inspire excellence in anyone who picks it up.
Management of Research Infrastructures : A South African Funding Perspective
This book provides an overview of the building blocks necessary for managing, steering and guiding the establishment of a research infrastructure (RI). It offers valuable insights into RI investment, access and management at the academic, grants management, agency and policy level, and serves as a useful guide for the research community, students, and those in the private sector wishing to understand the approaches and opportunities involved in the establishment, maintenance and management of research infrastructure platforms.
Civil engineering structures according to the Eurocodes : Inspection and maintenance
This standard assumes that the structure, after completion, is used as intended in the project and subject to planned inspection and maintenance to meet the expected project lifetime and to detect any unforeseen weakness or behavior" (EN 13670 4.1)An important decision factor in the design of new structures and repairs to existing structures is the lifetime or expected service life. This concept, which is common for civil engineering works, has been extended to all engineering and building works by applying the European Structural Design Codes.
Civil engineering for disaster risk reduction
Brings together all diverse disciplines of civil engineering and related areas (for example, geotechnical engineering, water resources engineering, structural engineering, transportation engineering, environmental engineering, construction management, GIS, and remote sensing) towards a common goal of disaster resilience through an interdisciplinary approach. It contains methods and case studies focusing on civil engineering solutions to reduce the disaster risk. The book contents are aligned in line with the priorities set by UN-Sendai Framework for Disaster Risk Reduction and UN-SDGs to promote a global culture of risk-awareness and disaster reduction. The book will be a useful comprehensive reference for disaster risk reduction beneficial for engineering students, teaching faculty, researchers, industry professionals and policymakers.
Bridge Management 5 : Inspection, maintenance, assessment and repair ; Proceedings of the 5th International Conference on Bridge Management, organized by the University of Surrey, 11–13 April 2005
The last five years have seen the art of bridge management develop into a mature subject. Bridge owners and engineers recognise the importance of implementing fully operational bridge management strategies to ensure that all road and rail bridges remain functional for as long as possible.Bridge structures form a major part of the vast financial investment in infrastructure and consequently their careful management involving structural appraisal, repair and strengthening is of paramount importance.
Bridge design for economy and durability : Concepts for new, strengthened and replacement bridges
Describes a number of new or updated bridging concepts which were developed and successfully applied during the author's forty years of close involvement with UK and international bridge design, construction, maintenance and research. The concepts mainly apply to the small/medium span range of bridges and viaducts and contribute to one or more of the following features: design and construction economy in both time and money ease of inspection and minimum maintenance ride quality and safety good appearance strengthening when required with minimum traffic disruption
Automation in construction toward resilience : Robotics, smart materials and intelligent systems
Presents all aspects of automation in construction pertaining to the use of information technologies in design, engineering, construction technologies, and maintenance and management of constructed facilities. The broad scope encompasses all stages of the construction life cycle from initial planning and design, through the construction of the facility, its operation, and maintenance, to the eventual dismantling and recycling of buildings and engineering structures
Appraisal and repair of of building structures
This book is a practical guide to the detection and remedy of faults in claddings and fixings on buildings. It sets out the problems involved in common cladding systems for buildings, and relates these problems to all the materials used: stone, masonry, concrete and glass-reinforced composites.
Aging, shaking, and cracking of infrastructures : From mechanics to concrete dams and nuclear structures
Focuses on the safety assessment of existing structures subjected to multi-hazard scenarios through advanced numerical methods. Whereas the focus is on concrete dams and nuclear containment structures, the presented methodologies can also be applied to other large-scale ones. This book is composed of seven sections: Fundamentals: theoretical coverage of solid mechnics, plasticity, fracture mechanics, creep, / seismology, dynamic analysis, probability and statistics / Damage: that can affect concrete structures, such as cracking of concrete, AAR, chloride ingress, and rebar corrosion, / Finite Element: formulation for both linear and nonlinear analysis including stress, heat and fracture mechanics, / Engineering Models: for soil/fluid-structure interaction, uncertainty quantification, probablilistic and random finite element analysis, machine learning, performance based earthquake engineering, ground motion intensity measures, seismic hazard analysis, capacity/fragility functions and damage indeces, / Applications to dams through potential failure mode analyses, risk-informed decision making, deterministic and probabilistic examples, / Applications to nuclear structures through modeling issues, aging management programs, critical review of some analyses, / Other applications and case studies: massive RC structures and bridges, detailed assessment of a nuclear containment structure evaluation for license renewal.
Adapting the built environment for climate change : Design principles for climate emergencies
Adapting the Built Environment for Climate Change: Design Principles for Climate Emergencies analyzes several scenarios and proposes various adaptation strategies for climate emergencies (heat waves, wildfires, floods, and storms). Divided into three themes, the book offers an organized vision of a complex and multi-factor challenge. It covers climatic resilience and building refurbishment, implications for service life prediction and maintainability, and climate adaptation in the maintenance and management of buildings. Sections cover infrastructure materials, climate emergency adaptation and building adaptation to heat waves, wildfires, floods and storms.
Knowledge and Institutions
Bridges the disciplinary boundaries within the social sciences to explore the role of social institutions in shaping geographical contexts, and in creating new knowledge. It includes theorizations as well as original empirical case studies on the emergence, maintenance and change of institutions as well as on their constraining and enabling effects on innovation, entrepreneurship, art and cultural heritage, often at regional scales across Europe and North America. Rooted in the disciplines of management and organization studies, sociology, geography, political science, and economics the contributors all take comprehensive approaches to carve out the specific contextuality of institutions as well as their impact on societal outcomes. Not only does this book offer detailed insights into current debates in institutional theory, it also provides background for scholars, students, and professionals at the intersection between regional development, policy-making, and regulation.
Capacity options for revenue management : Theory and applications in the air cargo industry
Hellermann addresses in his dissertation one of the most interesting - pects of this evolution for OR/MS, the parallel development of long-term and short-term markets for capacity and output, accompanied by a range of option and ?xed-commitment (i. e. , forward) contracts as the basic mec- nisms supporting transactions. This has been a fascinating topic for OR/MS research because it builds on the powerful framework of real options, while connecting directly to key operations decisions (capacity planning, network design, staf?ng, routing, maintenance, and so forth) of the equipment and technologies whose output is the focus of contracts.
Maintenance of brick and stone masonry structures
Deals with all the tasks related to brick and stone masonry structures, from the initial identification of defects and their diagnosis to their treatment and monitoring of its cost-effectiveness.



















