الصفحة 1
الصفحة 1
New Concepts of Antiviral Therapy
Antiviral drugs are important tools for treatment or prevention of viral infections. These drugs were first used for monotherapy, but nowadays combinations of antiviral agents are often part of a standard treatment as evidenced by e.g. HAART (highly active antiretroviral therapy). However, in almost every case of antiviral therapy, drug resistant viruses appear. In addition, the low oral bioavailability, toxicity and the number of severe side effects still pose significant problems. All of the latter issues limit the clinical usefulness and drive the need for improved antiviral strategies. These strategies include new drugs and targets, novel modes of action, vector-based treatments and even the block of defined genes by inhibiting mRNA formation (siRNA).
New approach to deal with fibromyalgia
You must have walked once among the colorful fields of flowers, enjoying their colors, aromas and touches, but have you ever thought that these beautiful creatures could contain many constituents that have healing properties and be one day a part of your therapy ! Aromatherapy is a holistic healing treatment that uses natural plant extracts to promote health and well-being; it is used in the management of many diseases including a very common syndrome nowadays: Acute or chronic stress/ pain in localized body spots may trigger or aggravate symptoms knowon as fibromyalgia (FM). In this research we're going to discuss this syndrome which is very widespread, but rarely well-diagnosed and associated with many complex and unclear mechanisms. A new approach to deal with FM will be introduced to you subsequently.
Network Control and Engineering for QOS, Security and Mobility, III ; IFIP TC6 / WG6.2, 6.6, 6.7 and 6.8. Third International Conference on Network Control and Engineering for QoS, Security and Mobility, NetCon 2004 on November 2-5, 2004, Palma de Mallorca, Spain
This volume contains the proceedings of the Third International Conference on Network Control and Engineering for Quality of Service, Security and Mobility (Net-Con'2004), celebrated in Palma de Mallorca (Illes Balears, Spain) during November 2-5, 2004. This IFIP TC6 Conference was organized by the Universitat de les Illes Balears and sponsored by the following Working Groups: WG6.2 (Network and Internetwork Architectures), WG6.6 (Management of Networks and Distributed Systems), WG6.7 (Smart Networks) and WG6.8 (Mobile and Wireless Communications). The rapid evolution of the networking industry introduces new exciting challenges that need to be explored by the research community. The adoption of Internet as the global network infrastructure places the issue of quality of service among one of the hot topics nowadays: a huge diversity of applications with quite different service requirements must be supported over a basic core of protocols. Also, the open and uncontrolled nature of Internet enforces the need to guarantee secure transactions among users, thus placing security as another hot topic. Finally, the explosion of mobility and its integration as part of the global infrastructure are probably now the most challenging issues in the networking field.
Multi-Agent Systems and Applications IV ; 4th International Central and Eastern European Conference on Multi-Agent Systems, CEEMAS 2005, Budapest, Hungary, September 15-17, 2005, Proceedings
In the very competitive field of agent oriented conferences and workshops nowadays (such as AAMAS, WI/IAT, EUMAS, CIA, MATES) the special profile of CEEMAS is that it is trying to bridge the gap between applied research achievements and theoretical research activities. Our ambition is to provide a forum for presenting theoretical research with an evident application potential, implemented application prototypes and their properties, as well as industrial case studies of successful (but also unsuccessful) agent technology deployments. This is why the CEEMAS proceedings volume provides a collection of research and application papers. The technical research paper section of the proceedings (see pages 11–499) contains pure research papers as well as research results in application settings while the application papers section (see pages 500–530) contains papers focused on application aspects. The goal is to demonstrate the real life value and commercial reality of multi-agent systems as well as to foster communication between academia and industry in this field.
Mobility Aware Technologies and Applications ; 2nd International Workshop, MATA 2005, Montreal, Canada, October 17 -- 19, 2005, Proceedings
The beginning of the twenty-first century is characterized by global markets, and the mobility of people is becoming an important fact of life. Consequently, the mobile user is demanding appropriate technical solutions to make use of customized information and communication services. In this context the notion of next-generation networks (NGNs), which are driven by the convergence of the entertainment sector, the mobile Internet, and fixed/mobile telecommunications, is emerging. Such NGNs are aggregating a variety of different access networks and supporting the seamless connection of an open set of end-user devices, and due to the adoption of an all-IP network paradigm they enable a much better integration of voice and data services. Coincidently the buzzword ‘fixed mobile convergence’ (FMC) describes the current trend towards providing common services across fixed and mobile networks resulting in the medium term in the full integration of fixed and mobile telecommunication networks. The adoption of appropriate middleware technologies and the provision of - called service delivery platforms driven by the ongoing innovation in the field of information technologies provides today the technical foundation for supporting terminal, personal and service mobility and thus the implementation of real seamless information and communication services. Furthermore, users are nowadays looking, in light of an omnipresent service environment, for a much higher degree of customization and context awareness in the services they use. The papers in this volume look at these enabling mobility-aware technologies and their use for implementing mobility-aware and context-aware applications.
Inverse Problems and Imaging : Lectures given at the C.I.M.E. Summer School held in Martina Franca, Italy September 15–21, 2002
Nowadays we are facing numerous and important imaging problems: nondestructive testing of materials, monitoring of industrial processes, enhancement of oil production by efficient reservoir characterization, emerging developments in noninvasive imaging techniques for medical purposes - computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), X-ray and ultrasound tomography, etc. In the CIME Summer School on Imaging (Martina Franca, Italy 2002), leading experts in mathematical techniques and applications presented broad and useful introductions for non-experts and practitioners alike to many aspects of this exciting field. The volume contains part of the above lectures completed and updated by additional contributions on other related topics: a general presentation and introduction (Moscoso), X-ray tomography (Natterer), Electromagnetic imaging (Dorn, Bertete-Aguirre, Papanicolaou), coherent imaging in telecommunications in a multiple input-multiple output setup (Dorn), polarization based optical imaging (Moscoso), topological derivatives used in shape reconstruction related to inverse scattering problems (Carpio, Rapún), Point interactions (Dell’Antonio, Figari, Teta).
Internal fixation of femoral neck fractures : An Atlas
Femoral neck fractures occur primarily in the elderly population, and nowadays arthroplasty is chosen most frequently as a treatment solution. In the era of financial restrictions in health care system non-invasive internal fixation is an attractive choice, because in addition to the lower immediate costs the rehabilitation period might also be shorter. In this illustrated atlas the authors deal with epidemiological aspects, anatomical and biomechanical specialities of the given region, diagnostic and management potentials, satisfactory both for orthopaedic and trauma specialists. By means of presenting minimally invasive technique step-by-step, and their own results, the aim is to persuade the reader that the ratio of complications remarkably can be diminished by urgent surgery, based on selective indication criteria. Aspects of postoperative treatment and rehabilitation are also clarified in details.
Interfacial Nanochemistry : Molecular Science and Engineering at Liquid-Liquid Interfaces
The presence of liquid-liquid interface means that real liquids are far from ideal liquids that must be miscible with any kinds of liquids and have no interface. Thus it can be said that the non-ideality of liquids might generate the liquid-liquid interface indeed and that biological systems might be generated from the non-ideal interface. The liquid-liquid interface has been, therefore, studied as a model of biological membrane. From pairing two-phases of gas, liquid and solid, nine different pairs can be obtained, which include three homo-pairs of gas-gas, liquid-liquid and solid-solid pairs. The gas-gas interface, however, is practically no use under the ordinary conditions. Among the interfaces produced by the pairing, the liquid-liquid interface is most slippery and difficult to be studied experimentally in comparison with the gas-liquid and solid-liquid interfaces, as the liquid-liquid interface is flexible, thin and buried between bulk liquid phases. Therefore, in order to study the liquid-liquid interface, the invention of innovative measurement methods has a primary importance.
Intelligent Document Retrieval : Exploiting Markup Structure
Collections of digital documents can nowadays be found everywhere in institutions, universities or companies. Examples are Web sites or intranets. But searching them for information can still be painful. Searches often return either large numbers of matches or no suitable matches at all. Such document collections can vary a lot in size and how much structure they carry. What they have in common is that they typically do have some structure and that they cover a limited range of topics. The second point is significantly different from the Web in general. The type of search system that we propose in this book can suggest ways of refining or relaxing the query to assist a user in the search process. In order to suggest sensible query modifications we would need to know what the documents are about. Explicit knowledge about the document collection encoded in some electronic form is what we need. However, typically such knowledge is not available. So we construct it automatically.
Information technology and Lawyers : Advanced technology in the legal domain, from challenges to daily routine
The area of Information Technology & Lawyers is a fascinating one. Both from a practical and an academic perspective the opportunities of applying Information Technology to law are tremendous. At the same time, however, lawyers are amongst the most conservative professionals, and traditional late adapters of technology. Nowadays the gap between Information Technology & Lawyers is closing more and more, in particular due to the Internet and the richness of legal sources that can be found online. This book provides material to further bridge the gap by showing people with a legal background what is possible with Information Technology now and in the near future, as well as by showing people with an IT background what opportunities exist in the domain of law.
Influence of Children on Family Purchase Decision
Nowadays, when it comes to the purchase decision there is several factors that affect it. It may be the promotion of the product or service, the way it’s presented, the price and too many other factors. But also, we can take the purchase decision from another point view where there may be people that influence it. These people may be friends, family, partners, children, or other. We conducted this research to investigate whether there is a children’s influence on the family purchase decision in Syria. It was based on deductive methodology that guided us to collect the primary data through distributing a questionnaire which was based on Likert five scale. As well as the sample that was set from infinite population.
Holomorphic Functions in the Plane and n-dimensional Space
Complex analysis nowadays has higher-dimensional analoga: the algebra of complex numbers is replaced then by the non-commutative algebra of real quaternions or by Clifford algebras. During the last 30 years the so-called quaternionic and Clifford or hypercomplex analysis successfully developed to a powerful theory with many applications in analysis, engineering and mathematical physics. This textbook introduces both to classical and higher-dimensional results based on a uniform notion of holomorphy. Historical remarks, lots of examples, figures and exercises accompany each chapter.
HDPE Geomembranes in Geotechnics
HDPE (High-density polyethylene) geomembranes are nowadays widely used for large-area liners and construction sealings in geotechnical engineering. Lining of water ponds, dams and dykes, landfill base liners and cover systems, remediation of contaminated sites, waterproof for tunnels, beneath highways and for various other civil engineering constructions are a few examples of application. The book covers all aspects of the HDPE geomembrane field: HDPE materials, geomembrane manufacture, textured geomembranes, properties, long-term performance and testing, installation and welding of geomembranes, quality assurance and control, leak detection, standards, recommendations and regulations. Various important topics are treated in detail. As part of it, the basic physical and chemical facts necessary to fully understand HDPE geomembrane properties and performance are carefully developed and explained.
Guardians of public value : How public organisations become and remain institutions
This book presents case studies of twelve organisations which the public have come to view as institutions. From the BBC to Doctors Without Borders, from the Amsterdam Concertgebouw Orchestra to CERN, this volume examines how some organisations rise to prominence and remain in high public esteem through changing and challenging times
Gesture smart control
Nowadays actions are increasingly being handled in electronic ways, instead of physical interaction. From earlier times biometrics is used in the authentication of a person. It recognizes a person by using a human trait associated with it like eyes (by calculating the distance between the eyes) and using hand gestures, fingerprint detection, face detection etc. Advantages of using these traits for identification are that they uniquely identify a person and cannot be forgotten or lost. These are unique features of a human being which are being used widely to make the human life simpler. Hand gesture recognition system is a powerful tool that supports efficient interaction between the user and the computer.
From parity violation to hadronic structure and more : Refereed and selected contributions from Grenoble, France, June 8-11, 2004
Almost 50 years after the proposal of Lee and Young in 1956 to test the hypothesis of parity violation in weak interactions and the subsequent experimental verification of parity violation by C. S. Wu, parity violation has today become a useful property of weak interactions. This is due to the fact that the focus nowadays has changed: parity violation in weak interactions is no more a topic of investigation but is used as a tool in many different fields ranging from nuclear physics to the search for the hidden extra dimensions requested by string theory. For our first workshop which took place June 5-8, 2002, at the Institut fiir Ke- physik of the Johannes Gutenberg-Universitat Mainz, we concentrated on the in vestigation of the strangeness contribution in the nucleon. This book contains the refereed and selected papers of the second workshop "From Parity Violation to Hadron Structure and more (Part II)", which took place June 8-11, in the Labo- toire de Physique Subatomique et de Cosmologie, in Grenoble. These papers appear in EPJAdirect, the electronic-only part of EPJA, and they are accessible without restrictions. They will also appear in printed form and can be ordered through Springer. The excellent presentations show the dramatic and steady progress in the accuracy of measured parity violating asymmetries over the last few years.
From decoding turbulence to unveiling the fingerprint of climate change : Klaus Hasselmann—Nobel Prize Winner in Physics 2021
Serves as a reference for the key elements and their significance of Klaus Hasselmann's work on climate science and on ocean wave research, all based on a rigorous and deeply physical thinking. It summarizes the original articles (mostly from the 1970 and 1980s; some of which are hard to find nowadays) and brings them in a present-day context.
Foundations and applications of MIS : A model theory approach
Foundations and Applications of MIS presents a unique systems theory approach to management information system (MIS) development. The development is driven by the need to eliminate ambiguity in specification, design and construction of the application software. Further, the authors show that the considerable effort being expanded nowadays on validation, verification and testing, as required in current software engineering practices, will be reduced. The approach also reinforces the belief that MIS development is independent of software development. The work presents an approach that provides a theoretical foundation for MIS development from the systems theoretic viewpoint along with practical applications ranging from a transaction processing system to a solver system. Both formal systems theory and automatic system generation based on the authors' newly extended Prolog offer a significant increase in the efficiency of specification, design and production of the application software, as well as an increase in the functional reliability of the software produced. The book assumes a working knowledge of elementary set theory, logic, and familiarity with some systems concepts, such as the automaton model.
Forest Environments in the Mekong River Basin
Deforestation and forest degradation have continued over a long period of time, and the deterioration of forest environment management services is becoming one of the biggest concerns in the world. Especially in large continental river basins, sel? sh political attitudes and individual interests in some regions predispose other regions to problems downstream and bring about international issues. The Mekong is just such a river basin and its water is the most important resource, interdependent with the forest conditions in the region. The lives of millions of people are sustained by the water of the Mekong River, and mutual understanding on water resource mana- ment is essential in this region. Consequently, appropriate environment management to control water resources is required of each country along with scienti? c knowledge of forest management, including forest hydrology.
Flexible Databases Supporting Imprecision and Uncertainty
This volume collects selected contributions on the application of heterogeneous methods for managing uncertainty and imprecision in databases. It contains both survey chapters on classic topics such as "flexible querying in databases", and up to date ontributions on "database models to represent imperfect data". Further, it includes specific contributions on uncertainty management in database integration, and in representing and querying semistructured and spatial data. These topics are of particular relevance nowadays with the diffusion of the internet since, most of the time, applications require information spread across several information sources and their integration may result in inconsistent information.
