الصفحة 1
الصفحة 1
Transdermal Drug Delivery System Patch of Testosterone
Transdermal Drug Delivery System is a medicated way to administer the active ingredient by the skin; the adhesive patch is the major representation of this system. It is placed on the healthy skin to transfer the medication through the dermas then into the bloodstream.” TDDS” historically used since 19th century. In comparison with other formulations, it has many advantages. Meanly avoidance of first pass metabolism. Several types of TDDS are prepared, they differ by the number of layers and components. Some examples have been cited and modern technology, like nanocarrier, is used in TDDS. One of the APIs used in TDDS is Testosterone; this hormone is produced by human body, secreted in stable amount, when it decreases it causes important troubles. We mention that this kind of pharmaceutical form is missed in our country (Syria) so, we studied the possibility to prepare this form in our research lab. And we take the Testosterone as API of our works.
Transdermal drug delivery : Concepts and application ; 1st ed.
Comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings.
Pharmaceutical formulations for older patients
Provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies.
Percutaneous Collagen Induction With Microneedling : A Step-by-Step Clinical Guide
Percutaneous Collagen Induction with Microneedling is a minimally invasive technique widely used to treat numerous dermatologic conditions such as facial and body scars, melasma, wrinkles, skin laxity, stretch marks, alopecies, vitiligo and scleroderma. Microneedling can also be used to optimize transdermal drug delivery for many substances. This technique uses modern microneedling devices containing multiple fine needles, typically 0.5 to 2.5 mm in length, which are mounted on a barrel and rolled onto the skin to create numerous perforations into the stratum corneum and the papillary dermis. These micro-wounds initiate the release of growth factors, triggering collagen and elastin formation, which results in dermal remodeling and skin resurfacing. This book provides a step-by-step approach to microneedling, based on the authors’ more than ten years of experience with the technique.
Ondansetron Patches
The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.
Novel Drug Delivery Systems for Chinese Medicines
Describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
Essential pharmaceutics
Essential Pharmaceutics is suited to this modern teaching style, and is the first book of its kind to provide the resources and skills needed for successful implementation of an active learning pharmaceutics course.This text offers a format that is specifically suited for integration in an active learning, team-based classroom setting
