تحسين النتائح
ترتيب حسب
من
الى
الصفحة 1
الصفحة 1
Lymphocyte Trafficking in Health and Disease
Since the discovery of chemokines and of chemokine receptors it has become evident that expression of chemokines at the site of inflammation may regulate the composition of cellular infiltrate, thereby directing the type of immune response. Recently, the molecular characterization of inherited disorders of immune system, (e.g., Wiskott-Aldrich syndrome, WHIM syndrome, leukocyte adhesion deficiency), which are characterized by cytoskeleton/adhesion defects or by altered response of chemokine receptors has contributed to clarifying the key players of immune response in normal physiology and in disease. This book, which deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention, offers a series of contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease.
Chemokine biology : Basic research and clinical application ; Vol.1 : Immunobiology of chemokines
The discovery of interleukin-8 close to 20 years ago initiated a new field of research touching on many aspects of immunology and inflammation. Interleukin-8 is just one member of a large class of structurally related chemoattractant proteins, known as chemokines. Chemokines are involved in the traffic control of leukocytes, which bear the corresponding chemokine receptors on their surfaces. Today, it is clear that chemokines affect all aspects of immunology and even many unrelated fields, such as tissue development and tumor cell metastasis. Their fundamental contributions to chronic inflammatory diseases make them a principal target for the development of novel, anti-inflammatory therapeutics.
Basis and Treatment of Cardiac Arrhythmias
Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.
Children in Tort Law Part II : Children as Victims
Since children are not as capable as adults to perceive the risks involved in many situations of daily life, they are at a high risk of suffering personal injuries, mainly resulting from home, school and traffic accidents. From the tort law perspective, this requires a specific treatment of children as victims. For the last few decades some legal systems have been trying to find new solutions for a better protection of children, while other legal systems still follow more traditional rules. After having tackled the problems concerning the position of children as tortfeasors in a previous book, in this book the same working team deals with the problems related to the position of children as victims. This book analyses both the traditional solutions found in some legal systems and the newer solutions offered by others and devotes specific attention to damage issues, apportionment of damage and insurance problems when the victim is a child.
Autonomous control for a reliable internet of services : Methods, models, approaches, techniques, algorithms, and tools
This open access book was prepared as a Final Publication of the COST Action IC1304 “Autonomous Control for a Reliable Internet of Services (ACROSS)”. The book contains 14 chapters and constitutes a show-case of the main outcome of the Action in line with its scientific goals. It will serve as a valuable reference for undergraduate and post-graduate students, educators, faculty members, researchers, engineers, and research strategists working in this field. The objective of this book is, by applying a systematic approach, to assess the state-of-the-art and consolidate the main research results achieved in this area.
Autonomes fahren : Technische, rechtliche und gesellschaftliche aspekte = Autonomous driving : Technical, legal and social aspects
This book provides answers to a wide range of these and other questions. Experts from Germany and the USA describe central topics related to the automation of vehicles on public roads from an engineering and social science perspective. They show which "decisions" are required of an autonomous vehicle or which "ethics" must be programmed. The authors discuss expectations and concerns that characterize the individual and societal acceptance of autonomous driving. An increased safety potential through autonomous vehicles is compared to the challenges and solution approaches that play a role in securing the safety concept. In addition, they explain what possibilities for change and opportunities arise for our mobility and the reorganization of traffic, not least for freight traffic. The book thus offers an up-to-date, comprehensive and scientifically sound examination of the topic of "autonomous driving".
Applications of Agent Technology in Traffic and Transportation
Building effective and user-friendly transportation systems is one of the big challenges for engineers in the 21st century. There is an increasing need to understand, model, and govern such systems at both the individual (micro) and the society (macro) level. Still, this raises significant technical problems, as transportation systems may contain thousands of autonomous, "intelligent" entities that need to be simulated and/or controlled. Therefore, traffic and transportation scenarios are extraordinarily appealing for Distributed Artificial Intelligence, and (multi-) agent technology in particular. This book gives an overview of recent advances in agent-based transportation systems. It includes both a state-of-the-art survey and reports on cutting-edge research in the field.
Anti-Spam Measures : Analysis and Design
The goal of this book is the methodical analysis of the potential, limitations, advantages, and drawbacks of anti-spam measures. These determine to which extent the measures can contribute to the reduction of spam in the long run. The range of considered anti-spam measures includes legislative, organizational, behavioral and technological ones. Furthermore, the conceptual development and analysis of an infrastructural email framework that features such a complementary application, is pointed out. The technological and organizational facets, the framework is analyzed twofold: its theoretical effectiveness is assessed with the aid of the formal model mentioned above, its storage and traffic requirements are analyzed quantitatively.
Advances in radar systems for target detection and tracking
Radar systems can provide the all-weather and all-time detection and tracking of targets of interest, and they have been extensively applied by the remote sensing community, in applications such as geological exploration, disaster forecasting, traffic monitoring, urban planning, environmental sciences, hydrology, littoral zones, oceans, etc. This reprint contains the several advance research studies on radar systems for target detection and tracking. It includes multipath ghost suppression, maneuvering target tracking, target detection, and other topics.
Advances in optical fiber communications
Given the increasing importance of a globally interconnected world, driven by modern digital services and the need for fast and reliable access to digital resources, communication networks are one of the key infrastructures in today’s society. In this scenario, fiber optics and optical devices play a leading role, as they allow for unprecedented growth in our capacity to cope with the ever-increasing traffic demand. Optical transmission solutions range from high-speed networks based on coherent detection and advanced modulation formats for long-haul-level communications, to networks still relying on traditional intensity modulation and direct detection receivers for short-reach communications, down to intra-data center scenarios.
Advances in Digital Forensics II
This book is the second volume in the anual series produced by the International Federation for Information Processing (IFIP) Working Group 11.9 on Digital Forensics, an international community of scientists, engineers and practitioners dedicated to advancing the state of the art of research and practice in digital forensics. The book contains a selection of twenty-five edited papers from the First Annual IFIP WG 11.9 Conference on Digital Forensics, held at the National Center for Forensic Science, Orlando, Florida, USA in the spring of 2006.
Advanced mathematical science for mobility society
The automotive industry has made steady progress in technological innovations under the names of Connected Autonomous-Shared-Electric (CASE) and Mobility as a Service (MaaS). Needless to say, mathematics and informatics are important to support such innovations. As the concept of cars and movement itself is diversifying, they are indispensable for grasping the essence of the future mobility society and building the foundation for the next generation. This book contains three main contents. 1. Mathematical models of flow 2. Mathematical methodsfor huge data and network analysis 3. Algorithm for mobility society The first one discusses mathematical models of pedestrian and traffic flow, as they are important for preventing accidents and achieving efficient transportation.
Ad-hoc Networks : Fundamental Properties and Network Topologies
This book clearly demonstrates how the Medium Access Control protocols impose a limit on the level of interference in ad-hoc networks. It has been shown that interference is upper bounded, and a new accurate method for the estimation of interference power statistics in ad-hoc and sensor networks is introduced here. Furthermore, this volume shows how multi-hop traffic affects the capacity of the network. In multi-hop and ad-hoc networks there is a trade-off between the network size and the maximum input bit rate possible per node. Large ad-hoc or sensor networks, consisting of thousands of nodes, can only support low bit-rate applications.
Bridge traffic loading : From research to practice
Delivers not just the state-of-the-art of vertical loading, but also to provide recommendations of best-practice for all the major challenges in the field – short-span, single and multi-lane bridge loading, dynamic allowance and long-span bridges. It reviews issues that continue to be debated, such as which statistical distribution is most appropriate, whether free-flowing or congested traffic governs and dealing with future traffic growth. Specialist consultants and bridge owners should find this invaluable, as will regulators.
Bridge design for economy and durability : Concepts for new, strengthened and replacement bridges
Describes a number of new or updated bridging concepts which were developed and successfully applied during the author's forty years of close involvement with UK and international bridge design, construction, maintenance and research. The concepts mainly apply to the small/medium span range of bridges and viaducts and contribute to one or more of the following features: design and construction economy in both time and money ease of inspection and minimum maintenance ride quality and safety good appearance strengthening when required with minimum traffic disruption
Advances on testing and experimentation in civil engineering : Materials, structures and buildings
Presents the most recent advances on testing and experimentation in civil engineering, especially in the branches of materials, structures, and buildings, complementing the authors’ publication Advances on Testing and Experimentation in Civil Engineering - Geotechnics, Transportation, Hydraulics and Natural Resources. It includes advances in physical modelling, monitoring techniques, data acquisition and analysis, and provides an invaluable contribution to the installation of new civil engineering experimental facilities.
Chinese Railways : Reform and Efficiency Improvement Opportunities
Although being huge by any measure, Chinese Railways are a bottleneck for economic growth in China. The state-owned enterprise returns a small profit but is severely capacity constrained and burdened with inefficiency. A comprehensive reform and efficiency improvement program needs to be developed in order to enable Chinese Railways to support further GDP growth in China. Application of industrial economics to the case of Chinese Railways suggests that moderate deregulation of e.g., the freight business could make Chinese Railways fit for future growth. Operational improvements need to complement this development, such as a redesign of the schedule or the introduction of value added services in the freight business. Based on interviews with Chinese experts, benchmarking with railways in the US, Germany, Russia, and Japan as well as broad coverage of Chinese-language sources, the book makes detailed recommendations on how to design a comprehensive turnaround program for Chinese Railways.
Mathematical and Computational Models for Congestion Charging
This book presents rigorous treatments of issues related to congestion pricing. The chapters describe recent advances in areas such as mathematical and computational models for predicting traffic congestion, determining when, where, and how much to levy tolls, and analyzing the impact of tolls on transporation systems. The analyses and methodologies developed in this book provide Mechanisms that aid in determining and comparing congestion pricing schemes; Methodologies for evaluating the efficiency of existing and proposed congestion pricing schemes; A means to predict the impact of pricing on urban transporation systems; and Information essential to the financial and political success of congestion pricing programs.
Managing Complexity : Insights, Concepts, Applications
Each chapter in Managing Complexity focuses on analyzing real-world complex systems and transferring knowledge from the complex-systems sciences to applications in business, industry and society. The interdisciplinary contributions range from markets and production through logistics, traffic control, and critical infrastructures, up to network design, information systems, social conflicts and building consensus. They serve to raise readers' awareness concerning the often counter-intuitive behavior of complex systems and to help them integrate insights gained in complexity research into everyday planning, decision making, strategic optimization, and policy.
Complex Dynamics in Communication Networks
Computer and communication networks are among society's most important infrastructures. The internet, in particular, is a giant global network of networks without central control or administration. It is a paradigm of a complex system, where complexity may arise from different sources: topological structure, network evolution, connection and node diversity, or dynamical evolution. The present volume is the first book entirely devoted to the new and emerging field of nonlinear dynamics of TCP/IP networks. It addresses both scientists and engineers working in the general field of communication networks.
