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Big data analytics and machine intelligence in biomedical and health informatics : Concepts, methodologies, tools and applications
Provides coverage of developments and state-of-the-art methods in the broad and diversified data analytics field and applicable areas such as big data analytics, data mining, and machine intelligence in biomedical and health informatics. Covers the latest advances and developments in health informatics, data mining, machine learning, and artificial intelligence. They have been organized with respect to the similarity of topics addressed, ranging from issues pertaining to the Internet of Things (IoT) for biomedical engineering and health informatics, computational intelligence for medical data processing, and Internet of Medical Things??(IoMT).
Management of the Addicted Patient in Primary Care
لThe text is logically organized and key information is easily accessible. The introductory section offers the reader important background and rationale for evaluating and treating addiction in primary care. Following a useful presentation of addiction "basics" (i.e., definitions, neurobiology, genetics, and the disease model), the majority of the book focuses on helping the physician gain insight and develop practical skills that can be readily implemented. A wealth of clinical assessment tools is provided, and the underlying psychosocial processes common to all forms of addiction are discussed. Both pharmacologic interventions and nonpharmalogic modalities are clearly outlined. Of particular note are specific cognitive-behavioral and motivational strategies that can be administered in an office-based setting. The role of community-based recovery support systems is considered as well. Since a complete understanding of why and when to refer is critical to the management of this often life-threatening condition, criteria for referral are detailed. Bulleted clinical "pearls" further aid the reader in gaining insight into treating this difficult patient population.
Male Sexual Function : A Guide to Clinical Management
Male Sexual Function: A Guide to Clinical Management, Second Edition, completely updates and reviews newer developments, including linking erectile dysfunction (ED) with lower urinary tract systems, advances in erectile physiology, and the appreciation of ED as a form of endothelial dysfunction and a harbinger of other potentially lethal forms of vascular disease. Treatments of ED as well as the background, causes, associated conditions, and diagnostic tools are also provided. This new updated edition also presents the facts of sexual function and dysfunction so that the practitioner can properly treat basic problems with easily prescribed therapies. Also included is a new chapter on cardiovascular disease as well as chapters on pelvic surgeries, intracavernous injections with vasoactive agents, and vacuum erection devices.
Les techniques de monitorage hémodynamique en réanimation = Hemodynamic monitoring techniques in intensive care
The hemodynamic monitoring of intensive care patients is undergoing major changes. Technological advances such as computerization and miniaturization have made it possible to considerably expand the range of assessment tools available at the bedside. Thus, the approach to cardiovascular monitoring - which was once readily "invasive" and global - is gradually becoming non-invasive and locoregional or even tissue. At the same time, the combined evolution of technology and physiological and pathophysiological concepts now provides the clinician with access to a variety of "functional hemodynamic monitoring". The aim of this book is to provide a better understanding of the interest and the limits of the hemodynamic parameters accessible by current hemodynamic monitoring techniques. It thus aims to ensure that the use of these techniques is perfectly mastered by resuscitators and anesthetists-resuscitators so that patient care is ultimately optimal.
Lapproccio e la gestione per processi in pneumologia = The process-based approach and management in pulmonology
The topics covered are highly relevant to the application of the methods and tools outlined in quality improvement programs. This is in an effort to enhance the specific skills of the pulmonologist, thus making him an effective and independent liaison with the relevant strategic management. With great sensitivity, the SIMeR (Italian Society of Respiratory Medicine) has chosen to sponsor this edition, the only one to date in the field of Pulmonology, whose contents are based on the proposals and work of the leaders of one of its most recently established Study Groups, the "Continuous Quality Improvement in Pulmonology" Study Group.
Climate-Smart Forestry in Mountain Regions
This book offers a cross-sectoral reference for both managers and scientists interested in climate-smart forestry, focusing on mountain regions. It provides a comprehensive analysis on forest issues, facilitating the implementation of climate objectives. CLIMO has provided scientific analysis on issues including criteria and indicators, growth dynamics, management prescriptions, long-term perspectives, monitoring technologies, economic impacts, and governance tools.
Chemometrics and Cheminformatics in Aquatic Toxicology
Chemometrics and Cheminformatics in Aquatic Toxicology delivers an exploration of the existing and emerging problems of contamination of the aquatic environment through various metal and organic pollutants, including industrial chemicals, pharmaceuticals, cosmetics, biocides, nanomaterials, pesticides, surfactants, dyes, and more. The book discusses different chemometric and cheminformatic tools for non-experts and their application to the analysis and modeling of toxicity data of chemicals to various aquatic organisms.
Chemical Biology and Drug Discovery
Gives the reader, through the specific selection of chemical-biological techniques and concepts, the necessary tools to be able to develop new ways of thinking and thus new therapeutic options in the complex field of chemical biology and drug development. The stated aim of this book is to provide concrete solutions and inspiration to students, (post)graduate students, and experienced scientists at universities as well as in industry in their problems.
Chapel and Haeneys essentials of clinical immunology
Contains the knowledge necessary to understand the diagnosis and treatment of immunological disorders. With easy-to-read text and a wealth of colour clinical images and diagrams, this well-regarded textbook introduces complex concepts using effective pedagogical tools such as bulleted lists, key point boxes, real-life case studies, practical examples, figures and tables, chapter introductions, and keywords in bold integrated in each chapter.
Carbohydrate-protein interactions : Methods and protocols
Provides new and updated tools for studying protein-carbohydrate interactions ranging from traditional biochemical methods to state-of-the-art techniques. This book focuses on four different research themes detailing methods for screening and quantifying CAZyme activity, investigating the interactions between proteins, carbohydrate ligands, methods for the visualization of carbohydrates, protein-carbohydrate complexes, structural and “omic” approaches for studying systems of CAZymes.
Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine
Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.
Cancer immunotherapy : Methods and protocols
Details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Campbell biology; 12th ed.
Delivers a trusted, accurate, current, and pedagogically innovative experience that guides students to a true understanding of biology. The author team advances Neil Campbell's vision of meeting and equipping students at their individual skill levels by developing tools, visuals, resources, and activities that encourage participation and engage students in their learning. Known for strategically integrating text and artwork, this trusted course solution works hand in hand with Mastering Biology to reinforce key concepts, build scientific skills, and promote active learning.
CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
Boreal Forest and Climate Change
There are several crucial feedbacks from forests to the climate system. The mechanisms for those feedbacks are elaborated in the book: they involve changes in the carbon cycle, albedo, N2O emissions and the production of aerosols. Much of this work is new and the feedback relationships have not yet been incorporated into models of the climate system. The book will be an important introduction for students and climate modellers alike, providing conceptual tools and ideas that are broadly applicable to terrestrial systems.
Biotechnology of medicinal plants with antiallergy properties : Research trends and prospects
Covers critically investigated information on medicinal plants prioritized for their anti-allergy properties. It offers insights into strategies related to the distribution, mechanism of action, and assessment of antiallergic medicinal plants, and also delves into crucial aspects of modern biotechnological tools, addressing their implementation challenges, presenting innovative approaches through case studies, and exploring opportunities for nanotechnologies. These elaborated discussions aim to raise awareness and bridge the gap between human health and the biodiversity of antiallergic medicinal plants.
Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts
Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: •Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries •Includes illustrative case studies that review six milestone bio-products •Discuses a wide selection of host strain types and disruptive bioprocess technologies
Biophysical characterization of functional peptides
Presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.
Biomarkers as targeted herbal drug discovery : A pharmacological approach to nanomedicines
Looks at the applications of biomarkers as important tools for herbal drug discovery, presenting research on phytoconstituents with advanced nanotechnological applications for healthcare benefits. Herbal drug discovery based on biomarkers is an emerging area in complementary and alternative medicine that has tremendous potential in healthcare. Conventional medications have limited efficacy and high toxicity, whereas herbal drugs are said to provide wide structural diversity that is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents, such as terpenoids, fatty acids, flavonoids and steroids, are well explored in the management and treatment of various disorders in this volume. These agents target various biomarkers such as nitric oxide (NO), cytokines, chemokines, adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic acid. Reviews the literature on inflammatory biomarkers in the treatment of diseases Looks at the development of herbal drug discovery based on biomarkers Explores emerging concepts of nanomedicines for herbal drug delivery Takes an interdisciplinary approach, with application to disciplines related to medical, pharmaceutical, biotechnological, Ayurvedic, Unani and biomedical engineering fields
Biology of Inositols and Phosphoinositides
This volume describes the current status of the biology of inositols and phosphoinositides with an emphasis on the development in the area since the publication of volume 26 in 1996 in this series. The progress made in dissecting the genetics, structure and evolution of the seminal enzyme for synthesis of inositol in the biological system has driven the understanding of the enzyme forward. With the current genomic and proteomic tools in place the new role of inositols, inositol phosphates and phosphoinositides in cell signaling or stress response has been explored. These advances are described.
