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الصفحة 1
الصفحة 1
Mass Vaccination : Global Aspects - Progress and Obstacles
Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.
Management of the Addicted Patient in Primary Care
لThe text is logically organized and key information is easily accessible. The introductory section offers the reader important background and rationale for evaluating and treating addiction in primary care. Following a useful presentation of addiction "basics" (i.e., definitions, neurobiology, genetics, and the disease model), the majority of the book focuses on helping the physician gain insight and develop practical skills that can be readily implemented. A wealth of clinical assessment tools is provided, and the underlying psychosocial processes common to all forms of addiction are discussed. Both pharmacologic interventions and nonpharmalogic modalities are clearly outlined. Of particular note are specific cognitive-behavioral and motivational strategies that can be administered in an office-based setting. The role of community-based recovery support systems is considered as well. Since a complete understanding of why and when to refer is critical to the management of this often life-threatening condition, criteria for referral are detailed. Bulleted clinical "pearls" further aid the reader in gaining insight into treating this difficult patient population.
Management of Prader-Willi Syndrome
Management of Prader-Willi Syndrome brings together the contributions of professionals with considerable expertise in diagnosis and management of PWS. Clinical, social, family, and community issues are explored and management strategies identified. The text presents historical, medical, and genetic information to orient the reader. The major portion deals with pragmatic guidelines, rather than research and diagnosis, and is directed to health and educational specialists in academic, clinical, and community settings. This manual is endorsed by The Prader-Willi Syndrome Association, which is recognized world-wide.
Lifestyle nutrition eating for good health by lowering the risk of chronic diseases
Provides physicians with an evidence-based introduction to nutrition science with a practical emphasis on how to apply this information to improve the health of their patients and enhance their own lives. From nutrition and atherosclerosis to erectile dysfunction and chronic kidney disease to osteoporosis, this comprehensive guide covers a wide range of conditions influenced by diet. It delves into specialized areas, such as nutrition for physically active people to the elderly, ensuring relevance for diverse patient populations. The reader will find detailed analysis of the Dietary Guidelines for Americans 2020–2025 and their applications and strategies for adopting healthy plant-based diets, such as Mediterranean, DASH, and vegan.
Lessons Learned : Risk Management Issues in Genetic Counseling
The only book devoted exclusively to this specialty, Lessons Learned details the risk management issues involved in genetic counseling practice, and offers solid strategies for minimizing the risk of costly, career-damaging malpractice suits. Schmerler clearly identifies areas of practitioner liability and demonstrates how they may be averted, so counselors can better manage their practice while lowering the risk of legal action. Examples drawn from relevant court cases illustrate typical issues in malpractice, negligence, and breach of contract suits. With this in-depth knowledge, readers can refine their goals toward increased self-protection as well as client care.
Les cancers digestifs = Digestive cancers
Digestive tumors are among the most common malignant tumors and represent a major public health problem. This is one of the areas that has evolved the most in recent years in oncology due to significant progress in diagnostic strategies and therapeutic management. It seems essential that this progress be implemented in the daily practice of physicians treating these tumors. This book, the result of multidisciplinary work, provides a practical and up-to-date approach to the management of malignant digestive tumors. The first chapters are devoted to general and original subjects such as epidemiology, genetics, the management of elderly subjects. A second part approaches in a pragmatic and practical way the principles of diagnostic and therapeutic management by localization. A third part, devoted to the practical realization of chemotherapy, takes stock of new therapeutic approaches, oral or locoregional chemotherapy. Finally, the last part of the book is dedicated to digestive cancer emergencies and the palliative management of these tumors.
Leptomeningeal Metastases
Leptomeningeal Metastases provides the reader with an overview of the state-of-the-art therapy for the leptomeningeal patient with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies. "Leptomeningeal metastases remains a devastating manifestation of hematologic malignancies and solid tumors. Leading figures in the field review the pathophysiology and clinical consequences of this process. State-of-the-art treatment strategies are presented highlighting advances in current management."
Le dépistage du cancer colorectal : État des lieux et perspectives = Colorectal cancer screening: Current status and perspectives
Prevention and screening are two major challenges for Public Health to reduce cancer mortality in our country. Screening for colorectal cancer is therefore quite exemplary. The number one cancer in both sexes in France, its incidence continues to increase due to the aging of the population. Its mortality remains high, in the order of fifty percent, despite the major therapeutic advances made in recent years. Preceded by a precancerous lesion - the adenomatous polyp, which can be removed by colonoscopy - colorectal cancer is also curable at the early stage. Finally, it can be the subject of a screening strategy, the impact of which has been demonstrated today on the reduction in mortality, when it is detected before any symptom by a simple test for blood in the stool followed by , in case of positivity, by a total colonoscopy. This book takes stock of the scientific rationale and the state of play of organized colorectal cancer screening in France. It is also an opportunity to discuss emerging techniques and strategies that can help improve the results of this screening if they prove their superiority over the current strategy. Intended primarily for doctors, this book is also intended for healthcare professionals and all those who, concerned about their health, have a proactive attitude in terms of screening and preventing this cancer.
Latency Strategies of Herpesviruses
This is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation.
La réanimation neurochirurgicale = Neurosurgical resuscitation
«decade of the brain », s’est ajouté en clinique humaine le développement des nouvelles techniques d’imagerie. Ceci a permis d'enterrer enfin certaines idées anciennes et de développer de nouvelles stratégies thérapeutiques fondées sur une meilleure compréhension des mécanismes physiopathologiques de l’agression cérébrale en transposant les résultats de la recherche fondamentale dans la pratique de tous les jours. Il ne fait aucun doute que le médecin, qu'il soit anesthésiste, réanimateur, urgentiste, qui serait passé « à côté » de cette période concernant la prise en charge globale du cerveau agressé se retrouverait distancé face à la prise en charge actuelle et n’aurait pas en main les moyens d’en comprendre sa justification. L’association de neuro-anesthésie réanimation de langue Française
Community-Acquired Pneumonia
Community-acquired pneumonia (CAP) is a disease associated with high morbidity and mortality, with at least one third of cases requiring hospitalization, exceeding the numbers admitted for myocardial infarction and stroke. Despite a broad armamentarium of antimicrobials available, it remains an important cause of death in industrialized countries. CAP is caused by a variety of pathogens with their order of importance dependent on the location and population studied. Despite the importance of CAP, reliable data and a recommended evidence-based therapy are lacking, and basic research must be improved. The goal of this volume is to present state-of-the-art knowledge on epidemiology, clinical presentation, immunology, pathology, and diagnosis including the identification of "new pathogens". Therapeutic approaches, antibiotics resistance, disease management and vaccination strategies are also covered. The volume is of interest to researchers and clinicians in virology, epidemiology and biomedicine.
Classics in total synthesis IV : new targets, strategies, and methods
A compilation of highly important synthetic methods which lead to complex molecules with valuable properties. From the complex architectures of natural products to the streamlined synthesis of functional molecules, each chapter in Classics in Total Synthesis IV unfolds a unique story. The interplay of mechanisms, reactivity, selectivity, and stereochemical aspects is thoroughly examined, echoing the pedagogical format that has become synonymous with this series. Well-designed graphics are included throughout, and all important parts of the reaction sequences are highlighted.
Chronic diseases and health care : New trends in diabetes, arthritis, osteoporosis, fibromyalgia, low back pain, cardiovascular disease, and cancer
CHRONIC DISEASES AND HEALTH CARE: New Patterns of Diabetes, Arthritis, Osteoporosis, Fibromyalgia, Low Back Pain, Cardiovascular Disease, and Cancer. This book evaluates new trends in epidemiology, health care costs, risk factors, treatment and rehabilitation outcomes, stress and coping strategies, social support, disability, patient education, and self-management for seven prevalent chronic diseases.
Chitosan-based nanocomposite materials : fabrication, characterization and biomedical applications
Discovery in the use of chitosan-based nanocomposites in biomedical applications, including the scope to which these novel materials have been incorporated by the community. It provides an exceptional insight into the strategies for the synthesis and chemical modifications of chitosan, characterization techniques, their use as anticancer agents, antimicrobial, antiviral, and antifungal agents, their role in the biomedical field, and applications in drug delivery, gene therapy, dentistry, orthopedics, etc. This book will also emphasize the challenges with previous signs of progress and way for further research, details relating to the current pioneering technology, and future perspectives with a multidisciplinary approach. Furthermore, it presents up-to-date information on the economics, toxicity, and regulations related to these novel materials.
Chemical Leasing Goes Global : Selling Services Instead of Barrels : A Win-Win Business Model for Environment and Industry
Chemical Leasing is an innovative business model within the sustainable management of chemicals. The economic benefit is achieved by selling chemicals services instead of increasing the sales volume. This book contains detailed descriptions and evaluations based on existing projects in Austria, Egypt, Russia and Mexico where in a broard range of sectors and companies the application of Chemical leasing was assisted. The book also contains political and scientific interpretations and analyses.
Chassins Operative Strategy in Esophageal Surgery
Chassin’s Operative Strategies in Esophageal Surgery offers the reader a succinct review of surgical techniques for disorders of the esophagus. Spanning from well-established legacy procedures to the most up-to-date minimally invasive approaches for GERD, this brilliantly illustrated atlas exclusively presents the theoretical basis of the operations as well as the strategies required to steer clear of common pitfalls. Educed from Chassin’s Operative Strategies in General Surgery.
Cerebral vasospasm : New strategies in research and treatment
More than 90 papers give a summary of clinical and basic studies on cerebral vasospasm, including reviews by leading researchers in this field. Several new frontiers are proposed for future research directions that will not only promote research from neurosurgery and neurology but also from other interconnecting fields of emergency medicine, electrophysiology, molecular biology, and vascular biology.
Cell Surface Receptors : A Short Course on Theory and Methods
Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest.
Cartilage Repair Strategies
Cartilage Repair Strategies is a comprehensive update of the present state of cartilage repair and regeneration. The information in this volume addresses what methods are effective, what methods are safe, and what methods will lead to an alteration in the short history of articular cartilage injury repair. Contributors present examinations of a variety of topics including the structure and function of articular cartilage, the evaluation of cartilage repair techniques, and the latest cartilage sensitive imaging techniques.
Carcinoma della cervice uterina : Eziopatogenesi e profilassi = Carcinoma of the uterine cervix : Aetiopathogenesis and prophylaxis
The volume offers a synthetic and updated picture of a complex topic that includes the multifactorial etiopathogenesis of cervical cancer, the characteristics of the virus, the dynamics of HPV infections, the histological lesions of the cervix leading to cervical cancer. and the characteristics of the various surgical treatments, the current strategies for early diagnosis through the use of molecular assays currently on the market, up to the trials of the two vaccines recently registered also in Italy.
