تحسين النتائح
ترتيب حسب
من
الى
الصفحة 1
الصفحة 1
Lipids in Health and Disease
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Asymmetric Cell Division
Cell biologists have recently become aware that the asymmetry of cell division is an important regulatory phenomenon in the fate of a cell. During development, cell diversity originates through asymmetry; in the adult organism asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to the aging of organisms with renewable cell compartments. Because of the concept of semi-conservative DNA synthesis, it was thought that the distribution of DNA between daughter cells was symmetric. The analysis of the phenomenon in cells during mitosis, however, revealed the asymmetry in the distribution of the genetic material that creates the drift contributing to aging of mammals. On the other hand, cancer cells can originate from a deregulation of asymmetry during mitosis in particular during stem cell expansion. The book describes the phenomenon in different organisms from plants to animals and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.
Algal Toxins : Nature, Occurrence, Effect and Detection
This volume contains the lectures and seminars given at the NATO Advanced Study Institute on “Sensor Systems for Biological Threads: The Algal Toxins Case”, held in Pisa, Italy in October, 2007. Algae can form heavy growths in ponds, lakes, reservoirs and sl- moving rivers throughout the world; algae can house toxins which are - ually released into water when the cells rupture or die. Hundreds of toxins have been identified so far. Detection methods, including rapid screening, have been developed to help us learning more about them, especially to find out which toxins are a real threat for people and what conditions encourage their production and accumulation. Early detection of algal toxins is an - portant aspect for public safety and natural environment, and significant efforts are underway to develop effective and reliable tools that can be used for this purpose.
Algal Toxins : Nature, Occurrence, Effect and Detection
This volume contains the lectures and seminars given at the NATO Advanced Study Institute on “Sensor Systems for Biological Threads: The Algal Toxins Case”, held in Pisa, Italy in October, 2007. Algae can form heavy growths in ponds, lakes, reservoirs and sl- moving rivers throughout the world; algae can house toxins which are - ually released into water when the cells rupture or die. Hundreds of toxins have been identified so far. Detection methods, including rapid screening, have been developed to help us learning more about them, especially to find out which toxins are a real threat for people and what conditions encourage their production and accumulation. Early detection of algal toxins is an - portant aspect for public safety and natural environment, and significant efforts are underway to develop effective and reliable tools that can be used for this purpose.
Mathematical methods and modelling in hydrocarbon exploration and production
Hydrocarbon exploration and production incorporate great technology challenges for the oil and gas industry. In order to meet the world's future demand for oil and gas, further technological advance is needed, which in turn requires research across multiple disciplines, including mathematics, geophysics, geology, petroleum engineering, signal processing, and computer science. This book addresses important aspects and fundamental concepts in hydrocarbon exploration and production. Moreover, new developments and recent advances in the relevant research areas are discussed, whereby special emphasis is placed on mathematical methods and modelling. The book reflects the multi-disciplinary character of the hydrocarbon production workflow, ranging from seismic data imaging, seismic analysis and interpretation and geological model building, to numerical reservoir simulation. Various challenges concerning the production workflow are discussed in detail.
Links between geological processes, microbial activities & evolution of life : Microbes and geology
Microbial activities influence water-rock interaction processes and chemical transport between the major geochemical reservoirs and the formation/transformation of minerals and rocks, whereas geological processes and geochemical controls influence the microbial ecology in extreme environments. How biological activity influences geological processes and what role these processes played in the geological evolution of the Earth are fundamental questions.
Carbonate Reservoir Characterization : An Integrated Approach
One principal need in petroleum recovery from carbonate reservoirs is the description of the three-dimensional distribution of petrophysical properties in order to improve performance predictions by means of fluid-flow computer simulations. The book focuses on a rock based approach for the integration of geological, petrophysical, and geostatistical methods to construct a reservoir model suitable to input into flow simulation programs. This second edition includes a new chapter on model construction and new examples of limestone, dolostone, and touching-vug reservoir models as well as improved chapters on basic petrophysical properties, rock-fabric/petrophysical relationships, calibration of wireline logs, and sequence stratigraphy.
Advances in the Geological Storage of Carbon Dioxide : International Approaches to Reduce Anthropogenic Greenhouse Gas Emissions
As is now generally accepted mankind’s burning of fossil fuels has resulted in the mass transfer of greenhouse gases to the atmosphere, a modification of the delicately-balanced global carbon cycle, and a measurable change in world-wide temperatures and climate. Although not the most powerful greenhouse gas, carbon dioxide (CO) drives climate 2 change due to the enormous volumes of this gas pumped into the atmosphere every day. Produced in almost equal parts by the transportation, industrial and energy-generating sectors, atmospheric CO concentrations have 2 increased by about 50% over the last 300 years, and according to some sources are predicted to increase by up to 200% over pre-industrial levels during the next 100 years. If we are to reverse this trend, in order to prevent significant environmental change in the future, action must be taken immediately.
