الصفحة 1
الصفحة 1
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Head and neck cancer recurrence : Evidence-based, multidisciplinary management

The first comprehensive, evidence-based reference on this complex condition, providing state-of-the-art strategies for treating and managing recurrence at each site within the head and neck. With this book at hand, specialists will have guidelines for detecting the presence of a tumor, evaluating the extent and likelihood of successful salvage, determining the most effective treatment modalities, and assessing the potential impact on outcome and function.

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Forefoot Reconstruction

For a long time, forefoot surgery had many disadvantages including a painful postoperative period and recurrence of deformities. New techniques – notably Scarf, the first metatarsal osteotomy and the Weil osteotomy of the lesser metatarsal – provide a significant improvement in the treatment of static forefoot disorders. The great toe osteotomy has also been greatly improved. Since 1991, the author has introduced these techniques in many countries, while developing and studying the corresponding implants and the postoperative period. He has also developed surgical management techniques that bridge these different osteotomies. More than 1000 surgeons around the world are using these techniques, which are now widely taught. In this second edition of the book the general presentation is clearer and more pleasant and many pictures have been replaced. Several topics are emphasized, notably the great toe proximal phalanx osteotomy, the joint preservative surgery in severe forefoot disorders, including revision after failed bunionectomy and rheumatoid forefoot following the "ms” point for an accurate and effective metatarsal shortening. Lastly, new procedures are exposed, particularly in Claw toe and hammer with the PIP plantar release and the surgery of the middle phalanx and also the Weil osteotomy of the first metatarsal in hallux limitus.

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Estimation in Conditionally Heteroscedastic Time Series Models

ARCH (autoregressive conditionally heteroscedastic), is well-suited for the description of economic and financial price. Nowadays ARCH has been replaced by more general and more sophisticated models, such as GARCH (generalized autoregressive heteroscedastic). This monograph concentrates on mathematical statistical problems associated with fitting conditionally heteroscedastic time series models to data. This includes the classical statistical issues of consistency and limiting distribution of estimators. Particular attention is addressed to (quasi) maximum likelihood estimation and misspecified models, along to phenomena due to heavy-tailed innovations. The used methods are based on techniques applied to the analysis of stochastic recurrence equations. Proofs and arguments are given wherever possible in full mathematical rigour. Moreover, the theory is illustrated by examples and simulation studies.

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Dimension and Recurrence in Hyperbolic Dynamics

The main objective of this book is to give a broad unified introduction to the study of dimension and recurrence in hyperbolic dynamics. It includes the discussion of the foundations, main results, and main techniques in the rich interplay of four main areas of research: hyperbolic dynamics, dimension theory, multifractal analysis, and quantitative recurrence. It also gives a panorama of several selected topics of current research interest. More than half of the material appears here for the first time in book form, describing many recent developments in the area such as topics on irregular sets, variational principles, applications to number theory, measures of maximal dimension, multifractal nonrigidity, and quantitative recurrence. All the results are included with detailed proofs, many of them simplified or rewritten on purpose for the book.

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Diagnostic Imaging in Head and Neck Cancer

This succinct compendium focuses on the key practical aspects of head and neck cancer imaging. It also provides essential information on handling and analyzing imaging data. Head and neck cancer is the sixth most common cancer worldwide. CT and MRI imaging are absolutely crucial to accurate diagnosis and staging, and radiologists have to be especially familiar with the anatomy of that region of the body. In addition, they must be highly proficient in interpreting radiographic images in order to judge the patterns of metastasis, response to treatment, and the signs and patterns of recurrence. This concise but detailed book describes the latest imaging modalities for all types of head and neck cancer diagnosis in light of recent technological advances. Featuring abundant high-quality images supplemented by advice from experts on the management of each cancer, it is a valuable resource for diagnostic and general radiologists, as well as all medical staff involved in the management of head and neck cancers.

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Cancer Stem Cells : Novel Concepts and Prospects for Tumor Therapy

This book describes the recent developments in the emerging field of cancer stem cells. Their possible impact for the identification of novel treatment paradigms for cancer are discussed. The book will mainly be of interest to scientists and clinicians involved in cancer research, or to students wishing to enter into this area.

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Atlas of genetic diagnosis and counseling

Many birth defects, although rare individually, are encountered in clinical practice and have now become treatable if properly diagnosed. In the Atlas of Genetic Diagnosis and Counseling, Harold Chen, MD, shares his almost 40 years of clinical genetics practice in a comprehensive pictorial atlas of 203 genetic disorders, malformations, and malformation syndromes. The author provides a detailed outline for each disorder, describing its genetics, basic defects, clinical features, diagnostic tests, and counseling issues, including recurrence risk, prenatal diagnosis, and management. Numerous color photographs of prenatal ultrasounds, imagings, cytogenetics, and postmortem findings illustrate the clinical features of patients at different ages, patients with varying degrees of severity, and the optimal diagnostic strategies. The disorders cited are supplemented by case histories and diagnostic confirmation by cytogenetics, biochemical, and molecular techniques, when available.

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An Introduction to the Mathematics of Money : Saving and Investing

This is an undergraduate textbook on the basic aspects of personal savings and investing with a balanced mix of mathematical rigor and economic intuition. It uses routine financial calculations as the motivation and basis for tools of elementary real analysis rather than taking the latter as given. Proofs using induction, recurrence relations and proofs by contradiction are covered. Inequalities such as the Arithmetic-Geometric Mean Inequality and the Cauchy-Schwarz Inequality are used. Basic topics in probability and statistics are presented.

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