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الصفحة 1
الصفحة 1
Cell Cycle Regulation
The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer.
Cancer Stem Cells : Novel Concepts and Prospects for Tumor Therapy
This book describes the recent developments in the emerging field of cancer stem cells. Their possible impact for the identification of novel treatment paradigms for cancer are discussed. The book will mainly be of interest to scientists and clinicians involved in cancer research, or to students wishing to enter into this area.
Analyzing T cell responses : How to analyze cellular immune responses against tumor associated antigens
Active specific immunotherapy is a promising but investigational modality in the management of cancer patients. Currently, several different cancer vaccine formulations such as peptides, proteins, antigen-pulsed dendritic cells, whole tumor cells, etc. in combination with various adjuvants and carriers are being evaluated in clinical trials (1-3). To determine the optimal cancer
Managing Risk and Information Security : Protect to Enable
Examine the evolving enterprise security landscape and discover how to manage and survive risk. While based primarily on the author’s experience and insights at major companies where he has served as CISO and CSPO, the book also includes many examples from other well-known companies and provides guidance for a management-level audience. Managing Risk and Information Security provides thought leadership in the increasingly important area of enterprise information risk and security. It describes the changing risk environment and why a fresh approach to information security is needed. Because almost every aspect of an enterprise is now dependent on technology not only for internal operations but increasing as a part of product or service creation, the focus of IT security must shift from locking down assets to enabling the business while managing and surviving risk. This edition discusses business risk from a broader perspective, including privacy and regulatory considerations. It describes the increasing number of threats and vulnerabilities and offers strategies for developing solutions. These include discussions of how enterprises can take advantage of new and emerging technologies—such as social media and the huge proliferation of Internet-enabled devices—while minimizing risk.
Logica Universalis : Towards a General Theory of Logic
Modern logic has been intimately connected with algebra since its origins in figures such as Boole, De Morgan, and Peirce. But while universal algebra is a long recognized field, universal logic has only recently been named as such. This is perhaps because classical logic was until relatively recently taken by many as the "one true logic". But with the proliferation of special purpose non-classical logics in recent years, universal logic is clearly a field whose time has come. This book contains many excellent papers demonstrating the value of this approach.
