الصفحة 1
الصفحة 1
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Computational biology in drug discovery and repurposing

Takes an in-depth look at the emerging and prospective field of computational biology and bioinformatics, which possesses the ability to analyze large accumulated biological data collected from sequence analysis of proteins and genes and cell population with an aim to make new predictions pertaining to drug discovery and new biology. The book explains the basic methodology associated with a bioinformatics and computational approach in drug designing. It then goes on to cover the implementation of computational programming, bioinformatics, pharmacophore modeling, biotechnological techniques, and pharmaceutical chemistry in designing drugs. The major advantage of intervention of computer language or programming is to cut down the number of steps and costs in the field of drug designing, reducing the repeating steps and saving time in screening the potent component for drug or vaccine designin

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Cardiac gene therapy : Methods and protocols

Discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Advanced chemical biology : chemical dissection and reprogramming of biological systems

Organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections.

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Adaptive dynamic programming for chemotherapy drug delivery

Focuses on the practical application of Adaptive Dynamic Programming (ADP) in chemotherapy drug delivery, taking into account clinical variables and real-time data. ADP's ability to adapt to changing conditions and make optimal decisions in complex and uncertain situations makes it a valuable tool in addressing pressing challenges in healthcare and other fields. As optimization technology evolves, we can expect to see even more sophisticated and powerful solutions emerge.

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An assessment framework for compliance with international space law and norms : Promoting equitable access and Use of space for emerging actors

proposes a framework for assessing countries’ levels of compliance with international space law and norms. It begins by exploring the development of two movements – the evidence-based policymaking and programming movement, and the rise of ratings and rankings research – and their growth across various disciplines. The analysis suggests that such efforts are useful in gauging the behavior of countries in space according to how well they adhere to existing space law and norms. To date, there is no comprehensive, periodic, and systematic measure of countries’ efforts to comply with space law and norms; this work endeavors to fill that gap by offering a framework in which to assess compliance.

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Mastering Oracle SQL and SQL*Plus

This exceptional book explains fundamentals in detail, supported by realistic examples, while most other books on the market do not properly cover such basics. If you work with relational databases you need to understand the SQL language. And you will gain full competence to define, access, and manipulate data in an Oracle database, if you do so following this book's guidance.

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Many-Core Computing : Hardware and software

Provides a timely and coherent account of the recent advances in many-core computing research. Starting with programming models, operating systems and their applications; it presents runtime management techniques, followed by system modelling, verification and testing methods, and architectures and systems. Computing has moved away from a focus on performance-centric serial computation, instead towards energy-efficient parallel computation. This provides continued performance increases without increasing clock frequencies, and overcomes the thermal and power limitations of the dark-silicon era. As the number of parallel cores increases, we transition into the many-core computing era. There is considerable interest in developing methods, tools, architectures and applications to support many-core computing.

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Machine Learning Algorithms Using Python Programming

Presents the key concepts of Machine Learning which includes Python concepts and Interpreter, Foundation of Machine Learning, Data Pre-processing, Supervised Machine Learning, Unsupervised Machine Learning, Reinforcement Learning, Kernel Machine, Design and analysis of Machine Learning experiment and Data visualization. The theoretical concepts along with coding implementation are covered. This book aims to pursue a middle ground between a theoretical textbook and one that focuses on applications. The book concentrates on the important ideas in machine learning.

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Machine Ethics : From Machine Morals to the Machinery of Morality

Offers the first systematic guide to machine ethics, bridging between computer science, social sciences and philosophy. Based on a dialogue between an AI scientist and a novelist philosopher, the book discusses important findings on which moral values machines can be taught and how. In turn, it investigates what kind of artificial intelligence (AI) people do actually want.

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Mac OS X Leopard : Beyond the Manual

Good computer books make assumptions about the reader: what they do and don't know when they pick up the book, and what they want to know when they put it down. For each reader this could be very different; therefore, a book that suits one person may not be the best for another. Mac OS X Leopard: Beyond the Manual makes some assumptions too, ones that tend to differ from other Mac OS X books. First of all, we assume that you have used a computer in that past: that you know how to use a mouse and you know the proper place to stick a DVD to get it to play in your computer. We won't be showing you these things. (We will, however, demonstrate to our Mac converts how to “right click” on a trackpad with only one button!).

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Logics of Specification Languages

Dedicated chapters address : the use of ASM (Abstract State Machines) in the classroom; the Event-B modelling method; a methodological guide to CafeOBJ logic; CASL, the Common Algebraic Specification Language; the Duration Calculus; the logic of the RAISE specification language (RSL); the specification language TLA+; the typed logic of partial functions and the Vienna Development Method (VDM); and Z logic and its applications. Each chapter is self-contained, with references, and symbol and concept indexes. Finally, in a unique feature, the book closes with short commentaries on the specification languages written by researchers closely associated with their original development.

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Logical and Relational Learning

This textbook covers logical and relational learning in depth, and hence provides an introduction to inductive logic programming (ILP), multirelational data mining (MRDM) and (statistical) relational learning (SRL). These subfields of data mining and machine learning are concerned with the analysis of complex and structured data sets that arise in numerous applications, such as bio- and chemoinformatics, network analysis, Web mining, natural language processing, within the rich representations offered by relational databases and computational logic.

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Logic Programming with Prolog

Logic Programming is the name given to a distinctive style of programming, very different from that of conventional programming languages such as C++ and Java. By far the most widely used Logic Programming language is Prolog. Prolog is a good choice for developing complex applications, especially in the field of Artificial Intelligence. This book does not assume that the reader is an experienced programmer or has a background in Mathematics, Logic or Artificial Intelligence. It starts from scratch and aims to arrive at the point where quite powerful programs can be written in the language. It is intended both as a textbook for an introductory course and as a self-study book. On completion the reader will know enough to use Prolog in their own research or practical projects. Each chapter has self-assessment exercises so that the reader may check their own progress. A glossary of the technical terms used completes the book.

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Logic for Computer Scientists

This book introduces the notions and methods of formal logic from a computer science standpoint, covering propositional logic, predicate logic, and foundations of logic programming. It presents applications and themes of computer science research such as resolution, automated deduction, and logic programming in a rigorous but readable way.The style and scope of the work, rounded out by the inclusion of exercises, make this an excellent textbook for an advanced undergraduate course in logic for computer scientists.

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LINQ for Visual C# 2008

Every C# programmer needs to learn about LINQ (Language–Integrated Query), Microsoft's breakthrough technology for simplifying and unifying data access from any data source. With LINQ, you can write more elegant and flexible code—not just to access databases and files, but to manipulate data structures and XML. This book is a short, yet comprehensive guide to the major features of LINQ and the significant enhancements introduced with .NET 3.5. There is no better source for getting a head–start on the future of these technologies than this book.

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LINQ for Visual C# 2005

LINQ for Visual C# 2005 is a short, yet comprehensive guide to the major features of LINQ. It thoroughly covers LINQ to Objects, LINQ to SQL, LINQ to DataSet, and LINQ to XML. It also details significant enhancements to C#, .NET, and ADO.NET.

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Linear Genetic Programming

Linear Genetic Programming examines the evolution of imperative computer programs written as linear sequences of instructions. In contrast to functional expressions or syntax trees used in traditional Genetic Programming (GP), Linear Genetic Programming (LGP) employs a linear program structure as genetic material whose primary characteristics are exploited to achieve acceleration of both execution time and evolutionary progress.

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LEGO® MINDSTORMS® NXT-G Programming Guide

LEGO MINDSTORMS NXT-G Programming Guide provides programming techniques simple enough to be understood by young programmers, ages 10 and up, and provides a test robot (with instructions) in the appendix for running the programs

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Legal Programming : Designing Legally Compliant RFID and Software Agent Architectures for Retail Processes and Beyond

LEGAL PROGRAMMING: Designing Legally Compliant RFID and Software Agent Architectures for Retail Processes and Beyond provides a process-oriented discussion of the legal concerns presented by agent-based technologies, processes and programming. It offers a general outline of the potential legal difficulties that could arise in relation to them, focusing on the programming of negotiation and contracting processes in a privacy, consumer and commercial context. The authors will elucidate how it is possible to create form of legal framework and design methodology for transaction agents, applicable in any environment and not just in a specific proprietary framework, that provides the right level of compliance and trust. Key elements considered include the design and programming of legally compliant methods, the determination of rights in respect of objects and variables, and ontologies and programming frameworks for agent interactions. Examples are used to illustrate the points made and provide a practical perspective.

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Learning PHP, MySQL & JavaScript : With jQuery, CSS & HTML5

You'll tackle dynamic web programming with the latest versions of today's core technologies: PHP, MySQL, JavaScript, CSS, HTML5, and key jQuery libraries.

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