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الصفحة 1
الصفحة 1
Computational biology in drug discovery and repurposing
Takes an in-depth look at the emerging and prospective field of computational biology and bioinformatics, which possesses the ability to analyze large accumulated biological data collected from sequence analysis of proteins and genes and cell population with an aim to make new predictions pertaining to drug discovery and new biology. The book explains the basic methodology associated with a bioinformatics and computational approach in drug designing. It then goes on to cover the implementation of computational programming, bioinformatics, pharmacophore modeling, biotechnological techniques, and pharmaceutical chemistry in designing drugs. The major advantage of intervention of computer language or programming is to cut down the number of steps and costs in the field of drug designing, reducing the repeating steps and saving time in screening the potent component for drug or vaccine designin
Cereals and millets
Genome Mapping and Molecular Breeding in Plants presents the current status of the elucidation and improvement of plant genomes of economic interest. The focus is on genetic and physical mapping, positioning, cloning, monitoring of desirable genes by molecular breeding and the most recent advances in genomics. The series comprises seven volumes: Cereals and Millets; Oilseeds; Pulses, Sugar and Tuber Crops; Fruits and Nuts; Vegetables; Technical Crops; and Forest Trees.
Arthroscopic rotator cuff surgery : A practical approach to management
The timely book answers key questions raised at instructional courses, such as how to convert from mini-open repair to all arthroscopic repair. The fundamentals, including patient positioning, suture anchor options, and knot tying, are covered in addition to state-of-the-art techniques.
Clinical oral medicine and pathology
The book has been well received internationally by a wide audience of clinicians, including general dentists, oral surgeons, otolaryngologists, primary care physicians, nurse practitioners, dental hygienists, physician assistants, and dermatologists, and sales have been strong among students and post-graduate residents training in medical, dental, and allied health fields, supporting the versatility of this work and serving as testimony to its value in both the academic and private practice arenas. Several key updates and improvements have been made to the second edition. All informational content has been updated to ensure accuracy and relevance, particularly in the rapidly evolving fields of oncology and pharmacology. A new chapter has been added entitled "Oral Sequelae of Cancer and Cancer Therapy" which better organizes and consolidates previous content while expanding on topics such as targeted therapies and hematopoietic stem cell transplantation. Additional clinical images have been included throughout the book so that the full clinical spectrum of any given condition is well-represented. Furthermore, the print quality, as well as the positioning and layout of the clinical images has been improved for optimal utility. Lastly, the summary boxes that follow each condition have been reconfigured with color-coded icons for improved definition, ease of use and cross-referencing.
Management Quality and Competitiveness : Lessons from the Industrial Excellence Award
This book showcases examples of excellent manufacturing companies who have succeeded in creating value and job growth in Western Europe. The examples show managers of industrial firms how a clearly articulated strategic position can be combined with excellent execution to achieve competitiveness in Europe, in spite of the usually cited disadvantage of high labor costs and rigidity. Not every company is alike — strategic positions differ, and the means of execution differ, but what is common is a clear plan together with mobilization of all employees to apply their abilities in supporting this common plan. The book is indispensable reading for all managers that are interested in improving competitiveness.
Bond Portfolio Optimization
1 The tools of modern portfolio theory are in general use in the equity markets, either in the form of portfolio optimization software or as an accepted frame- 2 work in which the asset managers think about stock selection. In the ?xed income market on the other hand, these tools seem irrelevant or inapplicable. Bond portfolios are nowadays mainly managed by a comparison of portfolio 3 4 risk measures vis ¶a vis a benchmark. The portfolio manager’s views about the future evolution of the term structure of interest rates translate th- selves directly into a positioning relative to his benchmark, taking the risks of these deviations from the benchmark into account only in a very crude 5 fashion, i.e. without really quantifying them probabilistically. This is quite surprising since sophisticated models for the evolution of interest rates are commonly used for interest rate derivatives pricing and the derivation of ?xed 6 income risk measures.
Beyond Safety Training : Embedding Safety in Professional Skills
Investigates why, despite more and more resources devoted to safety training, expectations are not entirely met, particularly in the industrial sectors that have already achieved a high safety level. It not only reflects the most precious viewpoints of experts from different disciplines, different countries, with experiences in various industrial fields at the cutting edge of theories and practices in terms of safety, professionalization and their relationships. It also consolidates the positioning of the Foundation for an Industrial Safety Culture, highlighting what is currently considered at stake in terms of safety training, taking into account the system of constraints the different stakeholders are submitted to. It reports some success stories as well as elements which could explain the observed plateau in terms of outcome. It identifies some levers for evolution for at-risk industry and outlines a possible research agenda to go further with experimental solutions.
Architectonics and parametric thinking : computational modeling for beginning design
Architectonics and Parametric Thinking begins by clearly positioning the potentials of parametric design through a series of chapters written by leaders in their respective industries. This helps to situate the vast potential of parametric softwares, allowing the reader to understand the full range of what is made possible by working computationally. Following this theoretical introduction, the book presents a manual that walks readers through the step-by-step construction of parametric modeling scripts built through an architectonic lens using clear, compelling diagrams.
Location Based Services and TeleCartography
Provides for the first time a general overview of research activities related to location and map-based services. These activities have emerged over the last years, especially around issues of positioning, spatial modelling, cartographic communication as well as in the fields of ubiquitious cartography, geo-pervasive services, user-centered modelling and geo-wiki activities. Topics cover an enormous range with heterogenous relationships to the main book issues. Whilst contemporary cartography aims at looking at new and efficient ways for communicating spatial information the development and availability of technologies like mobile networking, mobile devices or short-range sensors lead to interesting new possibilities for achieving this aim.
Lateral Alignment of Epitaxial Quantum Dots
Accurate positioning of self-organized nanostructures on a substrate surface can be regarded as the Achilles’ heel of nanotechnology. This perception also applies to self-assembled semiconductor quantum dots. This book describes the full range of possible strategies to laterally align self-assembled quantum dots on a substrate surface, starting from pure self-ordering mechanisms and culminating with forced alignment by lithographic positioning. The text addresses both short- and long-range ordering phenomena and paves the way for the future high integration of single quantum dot devices on a single chip. Contributions by the best-known experts in this field ensure that all relevant quantum-dot heterostructures are elucidated from diverse relevant perspectives.
Building the Inclusive City : Governance, Access, and the Urban Transformation of Dubai
This book is an anthropological urban study of the Emirate of Dubai, its institutions, and their evolution. It provides a contemporary history of disability in city planning from a non-Western perspective and explores the cultural context for its positioning. Three insights inform the author’s approach. First, disability research, much like other urban or social issues, must be situated in a particular place
African Languages and Literatures in the 21st Century
Examines the crucial role still played by African languages in pedagogy and literatures in the 21st century, generating insights into how they effectively serve cultural needs across the African continent and beyond. Boldly positioning African languages as key resources in the 21st century, chapters focus on themes such as language revolt by marginalized groups at grassroots level, the experience of American students learning African languages, female empowerment through the use of African languages in music, film and literary works, and immigration issues. The contributions are written by scholars of language, literature, education and linguistics, and will be of interest to students and scholars in these and related areas.
A window on the future of geodesy ; Proceedings of the International Association of Geodesy. IAG General Assembly, Sapporo, Japan June 30 - July 11, 2003
These proceedings represent the worldwide picture of the state of the art of geodesy. The volume comprehensively covers the most recent results and supplies a good review of the new ideas developing in the field, opening a window to the future of geodesy.
