الصفحة 1
الصفحة 1
New Vision of Metformin in treating cancer
The anti-diabetic drug metformin is rapidly emerging as a potential anticancer agent. Metformin is a biguanide that is effective in treating type 2 diabetes and the insulin resistance syndromes, improves insulin resistance by reducing hepatic gluconeogensis and by enhancing glucose uptake by skeletal muscle. Metformin can reduce the incidence of cancers and can reduce the mortality from cancers, increase the response to treatment cancer cells when using radiotherapy and chemotherapy, reduce the likelihood of relapse. Diabetes can be a factor in the occurrence of various types of cancer, and develop a variety of cancers such as colo-rectal, pancreas and liver cancers, compared to non-diabetic patients. Incidence of various cancers is high among patients of T2DM due to insulin resistance and mitogenic effects caused by hyperglycemia.
Mezzi di contrasto in ecografia : Applicazioni addominali = Contrast media in ultrasound : Abdominal applications
Lopera presenta unanalisi completa delle applicazioni dei mezzi di contrasto ecografici a livello addominale. La parte introduttiva di natura tecnica presenta la classificazione generale e le proprietà fisiche dei mezzi di contrasto ecografici, nonché una dettagliata classificazione delle tecniche ecografiche contrasto-specifiche; segue una parte speciale che descrive le applicazioni delle microbolle a livello del fegato, della milza e del rene. Vengono quindi presentate le applicazioni speciali e innovative dei mezzi di contrasto ecografici nellambito dei traumi delladdome, della patologia del pancreas, della parete intestinale e dei vasi addominali, e della valutazione del reflusso vescico-ureterale. Infine, viene proposta unanalisi economica relativa allapplicazione dei mezzi di contrasto ecografici nella caratterizzazione delle lesioni focali epatiche. Il libro è principalmente rivolto ai medici impegnati nellattività ecografica quotidiana, particolarmente in ambito internistico, che desiderano ampliare le proprie competenze nel settore dellecografia con mezzo di contrasto
Image Processing in Radiology : Current Applications
Few fields have witnessed such impressive advances as image processing in radiology. The progress achieved has revolutionized diagnosis and greatly facilitated treatment selection and accurate planning of procedures. This book provides a comprehensive and up-to-date description of how to use 2D and 3D processing tools in clinical radiology.
Genetic Engineering of Mesenchymal Stem Cells
MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care. This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.
Gastrointestinal Cancer
Gastrointestinal cancer includes cancer of the digestive system - the esophagus, colon, rectum, anus, liver, pancreas, and other digestive organs. Taken as a whole, there are an estimated 250,600 new cases in the US. Colon and rectum cancer is the third leading cause of cancer and cancer deaths in the US. Gastrointestinal Cancer is the third volume in the M.D. Anderson Cancer Care series, featuring the current standard approach to GI cancer care from the experts at M.D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include AJCC staging of gastrointestinal malignancies, recent advances in histopathology of gastroinestinal cancers, imaging techniques and endoscopy in the management of GI malignancies, colorectal cancer, liver cancer, gastric cancer, esophageal cancer, anal cancer, and palliative therapy. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as "key practice points" highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with GI cancer.
Ecografia e procedure interventistiche percutanee: Fegato, vie biliari e pancreas = Ultrasound and percutaneous interventional procedures : Liver, bile ducts and pancreas
The volume presents a concise overview of the most common percutaneous interventional procedures and is intended as a quick guide for the radiologist and sonographer who, more and more frequently, are required to perform interventional procedures on the liver, biliary tract and pancreas for both diagnostic and therapeutic.
Diseases of the Pancreas : Current Surgical Therapy
"Diseases of the Pancreas" is based on the latest comprehensive data about molecular mechanism of acute pancreatitis, chronic pancreatitis and pancreatic cancer. The diagnostic techniques including histology, radiology, sonography etc.
Diabetes Mellitus & Recent developments
Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defect in insulin secretion, insulin action, or both. Symptoms of marked hyperglycemia include polyuria, polydipsia, weight loss, sometimes with polyphagia, and blurred vision. Frequency of diabetic in the world About 1 in 11 adults worldwide now have diabetes mellitus, 90% of whom have type 2 diabetes mellitus (T2DM). Asia is a major area of the rapidly emerging T2DM global epidemic Classification Of Diabetic Mellitus. 1-Type 1 diabetes: which accounts for only5–10% of those with diabetes, results from a cellular-mediated autoimmune destruction of the cells of the pancreas. 2-Type 2 diabetes: which accounts for90 –95% of those with diabetes, result from insulin resistance. The chronic complications of diabetes mellitus affect many organ systems and are responsible for the majority of morbidity and mortality. Such as, retinopathy, diabetic foot, neuropathy, and nephropathy, sexual dysfunction, and skin changes.
Defects of Secretion in Cystic Fibrosis
This book brings together physicians, physiologists, and other scientists involved in basic research, from molecular biology to drug design and introduces novel investigative and therapeutic aspects of secretion disorders relevant in cystic fibrosis and related diseases. This book will be of interest to Molecular biologists, physiologists, scientists working in pharmaceutical research and drug developement, physicians and researchers in Cystic fibrosis and related diseases.
Controversies in Treating Diabetes : Clinical and Research Aspects
Controversies in Treating Diabetes: Clinical and Research Aspects covers commonly accepted forms of therapies and complications, as well as new and emerging advances, therapies and inadequacies in several standard treatments.
Contrast-Enhanced Ultrasound in Clinical Practice : Liver, Prostate, Pancreas, Kidney and Lymph Nodes
Concomitant with the improvement of contrast agents, different contrast-specific imaging modalities have been developed which, used in combination with USCA and a low mechanical index, allow continuous real-time grey-scale imaging. These recent technical improvements have opened new possibilities in the use of USCA in a variety of indications. Written by internationally renowned experts, the contributions gathered in this book give an overview of current and possible future new applications of USCA in routine and clinical practice.
Color Atlas of Immunocytochemistry in Diagnostic Cytology
Color Atlas of Immunocytochemistry in Diagnostic Cytology is an illustrated practical handbook that allows for quick reference in the selection and interpretation of markers in specific differential diagnoses in the daily practice of Diagnostic Cytology. This atlas includes 299 color illustrations.
Liver and Pancreatic Diseases Management
New therapeutical approaches, advances in oncology and in diagnostic imaging, which reduce the need for invasive techniques and reach an improvement in survival and quality of life in cancer, are considered in this book. Modern literature has been reviewed with special reference to articles of general interest. In the clinical management of patients with liver, bile duct and pancreas diseases, it is important to assess the degree of disturbance and to diagnose the causative insult, and therefore clinical and laboratory methods of assessing each of these pathologies are of high interest. This version is an up-to-date account of diseases of the liver, biliary tract and pancreas, including transplantation, which we trust will be of value for surgeons, physicians and pathologists and also a reference book for medical students.
Atlas of Upper Gastrointestinal and Hepato-Pancreato-Biliary Surgery
Atlas of Upper Gastrointestinal and Hepato-Pancreato-Biliary Surgery covers in detail the technical aspects of all important procedures of the upper abdomen (esophagus, duodenum, stomach, liver, biliary system, pancreas, portal hypertension and spleen) including general, oncologic and transplantation surgery. Each chapter has been written by an expert renowned in his or her field and been reviewed by a second expert. All of the approximately 900 illustrations have been drawn by the same team of three artists of notable experience. The liver section follows the internationally accepted terminology of the Brisbane 2000 conference of the IHPBA. In this atlas experts of upper abdominal surgery share their experience and show how they do it - step by step.
