تحسين النتائح
ترتيب حسب
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الصفحة 1
الصفحة 1
Big data analytics and machine intelligence in biomedical and health informatics : Concepts, methodologies, tools and applications
Provides coverage of developments and state-of-the-art methods in the broad and diversified data analytics field and applicable areas such as big data analytics, data mining, and machine intelligence in biomedical and health informatics. Covers the latest advances and developments in health informatics, data mining, machine learning, and artificial intelligence. They have been organized with respect to the similarity of topics addressed, ranging from issues pertaining to the Internet of Things (IoT) for biomedical engineering and health informatics, computational intelligence for medical data processing, and Internet of Medical Things??(IoMT).
Marine Biodiversity : Patterns and Processes, Assessment, Threats, Management and Conservation
Understanding the functioning of Marine Ecosystems is the first step to measure and predict the influence of Man, and to find solutions for the enormous array of problems we face today. This volume is organised according to the four subthemes of the symposium and to issues commonly perceived as relevant by scientists concerned with the study, protection and management of Marine Biodiversity: patterns and processes, assessment, threats and management and conservation.
Marine Anthropogenic Litter
This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats.
March's Advanced Organic Chemistry : Reactions, Mechanisms, and Structure
The opening chapters of March's Advanced Organic Chemistry deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Further coverage concerns general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation. The relationship between structure and reactivity is also covered.
Manuale di accreditamento delle strutture diabetologiche = Accreditation manual of diabetic facilities
Healthcare quality is not a new issue, but it is often underestimated. The doctor focuses on his relationship with the patient, and is led to believe that technique and technology are sufficient to guarantee effective and efficient performance, regardless of the organizational system. Quality understood as "Total Quality Management" is a way to cross a border, to create knowledge, to break the armor of self-referentiality and that individualistic vision of work learned during university studies and consolidated by professional practice. The path of professional peer accreditation is the tool that the scientific society Associazione Medici Diabetologi has developed and provided to diabetologists to facilitate the understanding of ways of looking at the world of healthcare that are different from those they usually use.
Manual of Benirschke and Kaufmanns Pathology of the Human Placenta
Benirschke and Kaufmann's Pathology of the Human Placenta has long been regarded as the gold standard in the field. It is comprehensive and thorough and contains the detail necessary for those in the subspecialties of placental, perinatal and pediatric pathology. However, placentas are relatively common specimens and are not examined primarily by specialists in the field, but by general pathologists. Thus, there is a need for a more practical and concise manual that can be used by pathology trainees and generalists in their daily work. Manual of Benirschke and Kaufmann's Pathology of the Human Placenta will fill that need. The Manual is a practical, user-friendly guidebook for the general pathologist and pathologist in training for everyday, bench-side use. Organized in 27 chapters, the book will discuss placental development, general features, approach to the specimen by macroscopic and microscopic evaluation, all aspects of placental abnormalities and lesions, disease processes and the placenta, legal aspects of the placental examination, future directions and much more. The sections on macroscopic and microscopic evaluations feature quick-reference tables that allow the reader to identify abnormalities, learn the situations where they occur, and refer back to the text for in-depth discussions. Each chapter will end with selected readings from Pathology of the Human Placenta for more detailed discussions, classic recommended readings, as well as an up-to-date bibliography of current literature. The manual features over 444 illustrations, more than 100 of them in full-color. A must-have for every pathologist and pathology resident.
Management of the Addicted Patient in Primary Care
لThe text is logically organized and key information is easily accessible. The introductory section offers the reader important background and rationale for evaluating and treating addiction in primary care. Following a useful presentation of addiction "basics" (i.e., definitions, neurobiology, genetics, and the disease model), the majority of the book focuses on helping the physician gain insight and develop practical skills that can be readily implemented. A wealth of clinical assessment tools is provided, and the underlying psychosocial processes common to all forms of addiction are discussed. Both pharmacologic interventions and nonpharmalogic modalities are clearly outlined. Of particular note are specific cognitive-behavioral and motivational strategies that can be administered in an office-based setting. The role of community-based recovery support systems is considered as well. Since a complete understanding of why and when to refer is critical to the management of this often life-threatening condition, criteria for referral are detailed. Bulleted clinical "pearls" further aid the reader in gaining insight into treating this difficult patient population.
Management of Acute Pulmonary Embolism
Management of Acute Pulmonary Embolism highlights traditional, novel, and evolving aspects of the diagnosis and treatment of pulmonary embolism (PE). Emphasis is placed on specific issues related to PE, including pregnancy, cancer, thrombophilia, and air travel. The authors critically review and interpret available data, and provide clear recommendations for diagnosis and therapeutic concerns in clinical management of PE patients. Management of Acute Pulmonary Embolism is organized in three precise sections - diagnosis, treatment, and special topics. Each section is up-to-date and detailed, and provides clear recommendations for diagnostic and therapeutic approaches to patients with PE in clinical practice. This practical volume is an essential starting point for future study for both medical students and established investigators.
Making Healthcare Safe : The Story of the Patient Safety Movement
This unique and engaging open access title provides a compelling and ground-breaking account of the patient safety movement in the United States, told from the perspective of one of its most prominent leaders, and arguably the movement’s founder, Lucian L. Leape, MD. Covering the growth of the field from the late 1980s to 2015, Dr. Leape details the developments, actors, organizations, research, and policy-making activities that marked the evolution and major advances of patient safety in this time span. In addition, and perhaps most importantly, this book not only comprehensively details how and why human and systems errors too often occur in the process of providing health care, it also promotes an in-depth understanding of the principles and practices of patient safety, including how they were influenced by today’s modern safety sciences and systems theory and design. Indeed, the book emphasizes how the growing awareness of systems-design thinking and the self-education and commitment to improving patient safety, by not only Dr. Leape but a wide range of other clinicians and health executives from both the private and public sectors, all converged to drive forward the patient safety movement in the US.
Magnetoreception and Magnetosomes in Bacteria
Recent developments in the research on magnetotactic bacteria are presented in this volume. Included are reviews on the formation and organization of magnetosomes, the genes controlling magnetosome biomineralization, and new cryogenic techniques to visualize novel cytoskeleton structures. Described here are potential nanobiotechnological applications of the magnetosome crystals, which have magnetic and crystalline characteristics unmatched by their inorganic counterparts.
Lysosomes
This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases.
Lysosomal Storage Disorders
This book is dedicated to patients affected by Lysosomal Storage Disorders, and especially to the National Gaucher Foundation (USA) and the Colombian Association of Patients with Lysosomal Storage Diseases (ACOPEL for its Spanish Acronym). Both organizations will share in the sales of this book.
Lung biology and pathophysiology
The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics.
Listeria Monocytogenes : Pathogenesis and Host Response
This comprehensive volume, written by experts in the field, includes concise and timely reviews of Listeria monocytogenes, one of the most intensively studied bacterial pathogens. Listeria monocytogenes is the cause of listeriosis, a potentially fatal disease that arises from the consumption of contaminated food. During the past two decades, studies of this organism have uncovered a wealth of information on its virulence factors, its genome organization, and its interactions with host cells and the immune system.
Lipids in Health and Disease
Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
Lessons Learned : Risk Management Issues in Genetic Counseling
The only book devoted exclusively to this specialty, Lessons Learned details the risk management issues involved in genetic counseling practice, and offers solid strategies for minimizing the risk of costly, career-damaging malpractice suits. Schmerler clearly identifies areas of practitioner liability and demonstrates how they may be averted, so counselors can better manage their practice while lowering the risk of legal action. Examples drawn from relevant court cases illustrate typical issues in malpractice, negligence, and breach of contract suits. With this in-depth knowledge, readers can refine their goals toward increased self-protection as well as client care.
Les infections urinaires = Urinary tract infections
Les Infections urinaires provides an update on knowledge concerning the epidemiology of community-based infection, on the mechanisms of bacterial resistance and on certain aspects of the disease useful to urologists as well as infectious diseases, gynecologists, emergency physicians and attending physicians. . Nosocomial urinary tract infection is approached from the perspective of risk factors. Acute and chronic prostatitis was the subject of a consensus conference supported by the World Health Organization within the framework of the International Consensus Conferences in Urology in Paris. The full text and the recommendations are reported with the consent of their authors. This book is an author's book and not an author's book because urinary tract infection is multiple, complex and justifies a multidisciplinary approach.
Le dépistage du cancer colorectal : État des lieux et perspectives = Colorectal cancer screening: Current status and perspectives
Prevention and screening are two major challenges for Public Health to reduce cancer mortality in our country. Screening for colorectal cancer is therefore quite exemplary. The number one cancer in both sexes in France, its incidence continues to increase due to the aging of the population. Its mortality remains high, in the order of fifty percent, despite the major therapeutic advances made in recent years. Preceded by a precancerous lesion - the adenomatous polyp, which can be removed by colonoscopy - colorectal cancer is also curable at the early stage. Finally, it can be the subject of a screening strategy, the impact of which has been demonstrated today on the reduction in mortality, when it is detected before any symptom by a simple test for blood in the stool followed by , in case of positivity, by a total colonoscopy. This book takes stock of the scientific rationale and the state of play of organized colorectal cancer screening in France. It is also an opportunity to discuss emerging techniques and strategies that can help improve the results of this screening if they prove their superiority over the current strategy. Intended primarily for doctors, this book is also intended for healthcare professionals and all those who, concerned about their health, have a proactive attitude in terms of screening and preventing this cancer.
Lantibiotics as alternative therapeutics
Explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.
La scuola dell’atopia = The school of atopy
The need to clarify the current concepts of atopy, which for too long have oscillated between a primitive purely clinical vision and a subsequent purely immunological one, had been ripe for some time. Understanding that the role of immunoglobulins E is not exhaustive and accepting the Solomonic division between intrinsic and extrinsic atopy were the first two fundamental steps. Recent discoveries of the role of innate immunity, and therefore of antimicrobial peptides, have opened fundamental spaces for understanding in atopy and beyond. What now appears clear is that atopy is not the disease of an organ but rather a defect in the membranes that delimit our "self". The fact that these membranes are called skin, intestines, conjunctiva, bronchi or whatever has artificially fragmented the understanding and treatment of a unitary phenomenon. This book seeks to summarize the different experiences but above all to be a stimulus to ensure that medicine focuses constructively on the same target. If this is the case, we will no longer see "religious wars" between scientists and practicing doctors or, even worse, between the different specialists vying for the patient. If atopy, as we believe, is a global problem, it can only be adequately addressed in a multidisciplinary context and in a collaborative atmosphere, not only between doctor and doctor but also between doctor and patient.
