الصفحة 1
الصفحة 1
Online Investing on the Australian Sharemarket : How to Research, Trade and Invest in Shares and Securities Online
Offers step-by-step guidance on choosing an online broker, accessing and making best use of online share investing resources, planning trades, identifying profit-making opportunities, timing of and placing online orders, managing investment risks, and much more.
Old Buildings New Designs
Increasingly, architects are hired to design new work for existing structures. Whether for reasons of preservation, sustainability, or cost-effectiveness, the movement to reuse buildings presents a variety of design challenges and opportunities. Old Buildings, New Designs is an Architecture Brief devoted to working within a given architectural fabric from the technical issues that arise from aging construction to the controversy generated by the various project stakeholders to the unique aesthetic possibilities created through the juxtaposition of old and new.
Official Statistics 4.0 : Verified Facts for People in the 21st Century
Explores official statistics and their social function in modern societies. Digitisation and globalisation are creating completely new opportunities and risks, a context in which facts (can) play an enormously important part if they are produced with a quality that makes them credible and purpose-specific. In order for this to actually happen, official statistics must continue to actively pursue the modernisation of their working methods.
Ocular Angiogenesis : Diseases, Mechanisms, and Therapeutics
Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches. Comprehensive and multidisciplinary, Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics offers a novel view of the clinical features of pathological angiogenesis in the eye, the molecular and environmental switches that govern vessel growth, and the tremendous opportunities for and progress made in the development of new therapeutics.
Nuucleic acids in medicinal chemistry and chemical biology : Drug development and clinical applications
Delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers. The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field
Nutrition, chemistry, and health effects of sugar, salt, and milkfat
Covers sugar, salt and milk fat from a chemical perspective, and presents an overview of the role of these ingredients in our food, focusing on their flavors, satiety-inducing properties, nutritional impact, and health effects. The book begins with a chapter devoted to the chemical composition of these taste enhancers and satiety-inducing components, followed by a chapter that sheds light on the persuasive tactics employed by the food industry and their impact on consumer behavior, ultimately discussing the complex relationship between marketing strategies and public health. In Chapter 3, the author presents case studies and explores the nutritional requirements of these ingredients, while considering their physiological effects ad potential implications for human health. In Chapter 4, the author evaluates current consumption patterns and their implications, analyzing trends, policies, and opportunities to shape healthier dietary choices.
Nurturing Science-based Ventures : An International Case Perspective
The challenge is to nurture entrepreneurial skills and ambitions in science and engineering academic students in the hope that they will consider the starting of a new business based on their research as a compelling alternative to more traditional employment opportunities. The book by Seifert, Leleux and Tucci addresses this challenge. … designed as a teaching support for courses on science-based entrepreneurship and it primarily targets engineering and science students. The book focuses on science based ventures that originate in technological break throughs, but entrepreneurs from all backgrounds can learn from it. Nurturing Science-Based Ventures charts the development of a new venture through five chapters.
NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders : from Genes to Therapeutics
The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders. The identification of multiple receptors for the members of the NPY and PYY family of peptides provides new opportunities for discovery of specific NPY antagonists and agonists that have vast clinical potential. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists, which are in clinical development for obesity. NPY Y1 receptor antagonists are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders is also actively pursued. The chapters in this book are written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.
Novel Optical Resolution Technologies
After theend ofthe 20th century, the science ofcrystallizationreached a truly exciting stage where new opportunities emerged in both theory and expe- ment. Variousphysical methodsare capable of resolving the surface as wellas the insid estructure of crystalsat the atomiclevel while newhigh-performance computing resourcesafford thecapability of modeling the complexlarge-scale alignments necessary to simulatecrystallizationinrealsystems. Asaresult, the science of crystallization has shifted gradually fromstatic to dynamic science and considerable progress now underlies the complex but beautiful cryst- lization process.The vastpotential ofcrystallizationasan- portant feld ofscience isfar beyondthesimple technologyofpharmaceutical industries during the 20th century.
New Aspects of Zirconium Containing Organic Compounds
Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportunities in carbon-carbon bond formation based on either carbene-centered reactions or on metal-templated processes which makes them indispensable in modern synthetic methodology. The most prominent metal carbenes are now either commercially available or easy to synthesize and handle with modern laboratory techniques. This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background, non-classical nucleophilic and cycloaddition patterns, chromium-templated benzannulation and photo-induced reactions, rhodium-catalyzed carbene transfer as well as the principles and applications of olefin metathesis which has coined the progress in synthetic methodology over the past decade. Designed for researchers in academia and industry as well as graduate students it presents the state-of-the-art potential of carbene complexes in modern organic synthesis.
Neutron Scattering in Biology : Techniques and Applications
The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.
Natural Products : Drug Discovery and Therapeutic Medicine
Although the natural product drug discovery programs of the large drug companies are now equaled by programs for the high throughput screening of synthetic compounds generated through combinatorial chemistry, natural compounds still hold great promise to overcome such problems as antibiotic resistance, the emergence of new diseases, the failure to conquer old diseases, and the toxicity of some contemporary medical products. In Natural Products: Drug Discovery and Therapeutic Medicine, a panel of recognized experts and leaders in the field discuss the past successes of natural products as medicines and review future possibilities arising from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discovery, to accessing microbial diversity, to investigating specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to exploiting specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Mute people aiding application
Communication is an essential tool for human survival. It is a fundamental and effective method of sharing thoughts, needs, feelings, and opinions. However, a large portion of the world's population lacks the ability to communicate with others. Such as the ones suffering from hearing loss, speech disability, or even both. Those disabilities have a significant impact on their lives in terms of work and relationships. The majority of these people are sometimes unable to support themselves financially due to the lack of job opportunities. Given these difficulties, we have decided to develop an application to help them overcome the obstacles they may encounter in their daily lives. After consulting with two deaf and mute people we customized an application that works in two ways. One of which is to translate their sign language in real time by using mobile camera and recognizing hand motion. The other works by converting text-to-voice, and accurately expressing the user’s emotions with the help of the facial emotion recognition.
Multidetector-Row CT of the Thorax
With the advent of multidetector-row technology, excitement has returned to computed tomography. Not only can we now image faster and with better resolution than ever before; more importantly, the development of sophisticated image acquisition techniques has enabled us to venture into areas previously considered to be beyond the scope of CT imaging. The knowledge, experience, and vision of a host of renowned international experts in cutting-edge thoracic applications of multidetector-row CT are condensed within this book. The result is a critical, comprehensive review of the novel opportunities, but also the new challenges, brought about by the development of ever-faster CT acquisition techniques.
Molecular Imaging ; An Essential Tool in Preclinical Research, Diagnostic Imaging, and Therapy
The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques.
Modelling Regional Scenarios for the Enlarged Europe : European Competitiveness and Global Strategies
The aim of this book is to tackle the question of what the European territory will look like over the next fifteen years by providing quali-quantitative territorial scenarios for the enlarged Europe, under different assumptions on future globalisation strategies of BRIC (Brazil, Russia, India and China) and East and West European countries. The approach is as neutral as possible vis-à-vis the results, leaving to a new forecasting model, the MASST model, built by the authors, to produce the tendencies and behavioural paths of regional GDP and population growth in each individual European region under alternative assumptions on the competitiveness strategies of different blocks of countries. The results are accompanied by strong policy messages intended to encourage long-term strategic thinking among a wide range of actors, scientists and policy makers in response to the risks and opportunities that the European territory will face.
Mobile Professional Voluntarism and International Development : Killing Me Softly?
This book explores the impact that professional volunteers have on the low resource countries they choose to spend time in. Whilst individual volunteering may be of immediate benefit to individual patients, this intervention may have detrimental effects on local health systems; distorting labour markets, accentuating dependencies and creating opportunities for corruption. Improved volunteer deployment may avoid these risks and present opportunities for sustainable systems change. The empirical research presented in this book stems from a specific volunteering intervention funded by the Tropical Health Education Trust and focused on improving maternal and newborn health in Uganda.
Mobile Edge Computing
It offers comprehensive, self-contained knowledge on Mobile Edge Computing (MEC), which is a very promising technology for achieving intelligence in the next-generation wireless communications and computing networks. The book starts with the basic concepts, key techniques and network architectures of MEC. Then, we present the wide applications of MEC, including edge caching, 6G networks, Internet of Vehicles, and UAVs. In the last part, we present new opportunities when MEC meets blockchain, Artificial Intelligence, and distributed machine learning (e.g., federated learning). We also identify the emerging applications of MEC in pandemic, industrial Internet of Things and disaster management.
Microdynamics Simulation
This volume deals with the simulation of metamorphic and tectonic microstrucutres in rocks with a special emphasis on the modelling package "Elle". The first part provides a review of the problems and opportunities in the modelling of microstructures, followed by an introduction to various numerical modelling techniques. In the second part examples of the modelling of different processes which alter rock microstructure are presented, beginning with individual processes and progressing to modelling multiple coupled processes.
Micro-, Meso- and Macro-Dynamics of the Brain
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The topics cover the most fascinating facets of neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory and mental illness, brain controlled robots, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Overall, this volume offers an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
