الصفحة 1
الصفحة 1
Nanotechnology in therapeutics : Basics and trends
Nanotechnology delivers a unique approach, which promises higher drug efficacy, targeted drug delivery, on demand delivery, biocompatibility, etc. For example, nanotechnology-based delivery systems can protect drugs from degradation and help reduce the number of doses required, make treatment a better experience and reduce treatment expenses and a number of nano-based systems allow delivery of insoluble drugs, allowing the use of previously rejected drugs or drugs which are difficult to administer.
Nano physical pharmaceutics
Nanomedicine is an emerging and rapidly evolving field, which could significantly help in early disease diagnosis, therapeutic improvement, novel therapeutic modality development, and medical expenditure reduction. The challenge remains, however, that the specially designed and carefully synthesized nanomedicines function poorly in animal verification despite great performance in vitro. A deeper understanding of the physicochemical properties of nanomedicine is the key. This book applies physical theories and models to determine the parameters for controlling the physicochemical properties of nanomedicines, including micelles, liposomes, and inorganic nanoparticles. Qualitative and quantitative relationships are established to provide guidance for nanomedicine design, characterization, and analysis. The text also compiles cutting-edge research in nanomedicine from the interdisciplinary team of the Department of Nanomedicine at Naval Medical University, China, which is currently establishing the characteristic discipline called Nano Physical Pharmaceutics. Edited by Wei Li, a prominent nanotechnology researcher, this book will appeal to anyone involved in nanotechnology, medicine, macromolecular science, biology, chemistry, and especially those with an interest in drug delivery or cancer therapy.
Biomedical applications and toxicity of nanomaterials
Covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
