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الصفحة 1
Computational and Statistical Approaches to Genomics
Computational and Statistical Approaches to Genomics, 2nd Edition, aims to help researchers deal with current genomic challenges. During the three years after the publication of the first edition of this book, the computational and statistical research in genomics have become increasingly more important and indispensable for understanding cellular behavior under a variety of environmental conditions and for tackling challenging clinical problems. In the first edition, the organizational structure was: data à analysis à synthesis à application. In the second edition, the same structure remains, but the chapters that primarily focused on applications have been deleted.
Bioinformatics of genome regulation and structure II
The conference was organized by the Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. The material covers the most recent topics in bioinformatics, including (i) regulatory genomic sequences: databases, knowledge bases, computer analysis, modeling, and recognition; (ii) large-scale genome analysis and functional annotation; (iii) gene structure detection and prediction; (iv) comparative and evolutionary genomics; (v) computer analysis of genome polymorphism and evolution; computer analysis and modeling of transcription, splicing, and translation; structural computational biology: structure- function organization of genomic DNA, RNA, and proteins; (vi) gene networks, signal transduction pathways, and genetically controlled metabolic pathways: databases, knowledge bases, computer analysis, and modeling; principles of organization, operation, and evolution; (vii) data warehousing, knowledge discovery and data mining; and (viii) analysis of basic patterns of genome operation, organization, and evolution.
Alpha-1 antitrypsin : Methods and protocols
Provides a collection of protocols that will allow researchers to further explore the multiple, fascinating activities of Alpha-1 Antitrypsin (AAT) isoforms in innate immunity, and gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Algorithms on Trees and Graphs : With Python Code
Introduces graph algorithms on an intuitive basis followed by a detailed exposition using structured pseudocode, with correctness proofs as well as worst-case analyses. Centered around the fundamental issue of graph isomorphism, the content goes beyond classical graph problems of shortest paths, spanning trees, flows in networks, and matchings in bipartite graphs. Advanced algorithmic results and techniques of practical relevance are presented in a coherent and consolidated way. Numerous illustrations, examples, problems, exercises, and a comprehensive bibliography support students and professionals in using the book as a text and source of reference. Furthermore, Python code for all algorithms presented is given in an appendix. Topics and features: Algorithms are first presented on an intuitive basis, followed by a detailed exposition using structured pseudocode / Correctness proofs are given, together with a worst-case analysis of the algorithms / Full implementation of all the algorithms in Python / An extensive chapter is devoted to the algorithmic techniques used in the book / Solutions to all the problems
Architectural colossi and the human body buildings and metaphors
Architectural Colossi and the Human Body discusses the role of Platonic and Cartesian philosophy and how philosophers such as Heidegger and Merleau-Ponty, and theoreticians such as Frascari and Pallasmaa, have seen, described and analysed the human body and the role of architecture and perception. Drawing upon three key case studies and by employing theoretical ideas of Venturi and others, this book will provide an understanding of the role of anthromorphism and the relation and use of the human body with reference to selected architects and artists.
Lifting Modules : Supplements and Projectivity in Module Theory
Extending modules are generalizations of injective modules and, dually, lifting modules generalize projective supplemented modules. There is a certain asymmetry in this duality. While the theory of extending modules is well documented in monographs and text books, the purpose of our monograph is to provide a thorough study of supplements and projectivity conditions needed to investigate classes of modules related to lifting modules. The text begins with an introduction to small submodules, the radical, variations on projectivity, and hollow dimension. The subsequent chapters consider preradicals and torsion theories (in particular related to small modules), decompositions of modules (including the exchange property and local semi-T-nilpotency), supplements in modules (with specific emphasis on semilocal endomorphism rings), finishing with a long chapter on lifting modules, leading up their use in the theory of perfect rings, Harada rings, and quasi-Frobenius rings.
Lectures on the Automorphism Groups of Kobayashi-Hyperbolic Manifolds
Presents a coherent exposition of recent results on complete characterization of Kobayashi-hyperbolic manifolds with high-dimensional groups of holomorphic automorphisms. These classification results can be viewed as complex-geometric analogues of those known for Riemannian manifolds with high-dimensional isotropy groups, that were extensively studied in the 1950s-70s. The common feature of the Kobayashi-hyperbolic and Riemannian cases is the properness of the actions of the holomorphic automorphism group and the isometry group on respective manifolds.
Lectures on Symplectic Geometry
Provides a fast introduction to symplectic geometry for graduate students with some knowledge of differential geometry, de Rham theory and classical Lie groups. This text addresses symplectomorphisms, local forms, contact manifolds, compatible almost complex structures, Kaehler manifolds, hamiltonian mechanics, moment maps, symplectic reduction and symplectic toric manifolds. It contains guided problems, called homework, designed to complement the exposition or extend the reader's understanding.
L’isomorphisme entre les tours de Lubin-Tate et de Drinfeld = The isomorphism between the Lubin-Tate and Drinfeld towers
This book contains a detailed and complete demonstration of the existence of an equivariate isomorphism between the Lubin-Tate and Drinfeld p-adic turns. The result is established in equal and unequal characteristics. There is also given as an application a proof that the equivariant cohomologies of these two turns are isomorphic, a result which has applications to the study of the local Langlands correspondence. During the proof, reminders and complements are given on the structure of the two preceding moduli spaces, the p-divisible formal groups and the p-adic rigid analytical geometry.
C*-algebras and Elliptic Theory
This volume contains the proceedings of the conference on "C*-algebras and Elliptic Theory" held in Bedlewo, Poland, in February 2004. It consists of original research papers and expository articles focussing on index theory and topology of manifolds.The collection offers a cross-section of significant recent advances in several fields, the main subject being K-theory (of C*-algebras, equivariant K-theory). A number of papers is related to the index theory of pseudodifferential operators on singular manifolds (with boundaries, corners) or open manifolds. Further topics are Hopf cyclic cohomology, geometry of foliations, residue theory, Fredholm pairs and others.
Braid Groups
Braids and braid groups have been at the heart of mathematical development over the last two decades. Braids play an important role in diverse areas of mathematics and theoretical physics. The special beauty of the theory of braids stems from their attractive geometric nature and their close relations to other fundamental geometric objects, such as knots, links, mapping class groups of surfaces, and configuration spaces. In this presentation the authors thoroughly examine various aspects of the theory of braids, starting from basic definitions and then moving to more recent results. The advanced topics cover the Burau and the Lawrence--Krammer--Bigelow representations of the braid groups, the Alexander--Conway and Jones link polynomials, connections with the representation theory of the Iwahori--Hecke algebras, and the Garside structure and orderability of the braid groups.
Binary Rare Earth Oxides
The book begins with a brief introduction to binary rare earth oxides, their physical and chemical stabilities, polymorphism, crystal structures and phase transformation and the association with current applications. The book goes on to present the band structure of the oxides using several quantum chemical calculations, which belong to a newly developed area in the binary rare earth oxides. Central to this chapter are the characterizations of electrical, magnetic and optical properties, as well as details of single crystal growth and particle preparation methods that have progressed in recent years. Later chapters concentrate on thermo-chemical properties and trace determination techniques. The final chapter contains a variety of useful applications in various fields such as phosphors, glass abrasives, automotive catalysts, fuel cells, solid electrolytes, sunscreens, iron steels, and biological materials.
Basic Notions of Algebra
Aims to present a general survey of algebra, of its basic notions and main branches.Those parts of the book devoted to the systematic treatment of notions and results of algebra make very limited demands on the reader: we presuppose only that the reader knows calculus, analytic geometry and linear algebra in the form taught in many high schools and colleges. The extent of the prerequisites required in our treatment of examples is harder to state; an acquaintance with projective space, topological spaces, differentiable and complex analytic manifolds and the basic theory of functions of a complex variable is desirable, but the reader should bear in mind that difficulties arising in the treatment of some specific example are likely to be purely local in nature, and not to affect the understanding of the rest of the book.
An Introduction to Sequential Dynamical Systems
This text is the first to provide a comprehensive introduction to SDS. Driven by numerous examples and thought-provoking problems, the presentation offers good foundational material on finite discrete dynamical systems which leads systematically to an introduction of SDS. Techniques from combinatorics, algebra and graph theory are used to study a broad range of topics, including reversibility, the structure of fixed points and periodic orbits, equivalence, morphisms and reduction. Unlike other books that concentrate on determining the structure of various networks, this book investigates the dynamics over these networks by focusing on how the underlying graph structure influences the properties of the associated dynamical system.
Advanced Linear Algebra
The first part of the book contains a careful but rapid discussion of the basics of linear algebra, including vector spaces, linear transformations, quotient spaces, and isomorphism theorems. The author then proceeds to modules, emphasizing a comparison with vector spaces. A thorough discussion of inner product spaces, eigenvalues, eigenvectors, and finite dimensional spectral theory follows, culminating in the finite dimensional spectral theorem for normal operators. The second part of the book is a collection of topics, including metric vector spaces, metric spaces, Hilbert spaces, tensor products, and affine geometry. The last chapter discusses the umbral calculus, an area of modern algebra with many important applications.
