الصفحة 1
الصفحة 1
Microfluidic Technologies for Miniaturized Analysis Systems
Microfluidic Technologies for Miniaturized Analysis Systems provides a comprehensive overview of the fluidic aspects of Lab-on-a-Chip technology. This book describes the most important and state-of-the-art microfluidic technologies and the underlying principles utilized in the implementation of fluidic protocols of miniaturized analysis systems. This book discusses many of the effects, outcomes, and techniques which are unique to microfluidic systems. The specific components of this technology toolbox are elucidated through research and examples presented by some of the most renowned experts in the field.
Design of Wireless Autonomous Datalogger ICs
The book starts with a comprehensive introduction on the most important design aspects and trade-offs for miniaturized low-power telemetric dataloggers. After the general introduction follows an in-depth case study of an autonomous CMOS datalogger IC for the registration of in vivo loads on oral implants. After tackling the design of the datalogger on the system level, the design of the different building blocks is elaborated in detail, with emphasis on low power
CMOS Biotechnology
"CMOS Biotechnology reviews the recent research and developments joining CMOS technology with biology. Written by leading researchers these chapters delve into four areas including: Microfluidics for electrical engineers / CMOS Actuators CMOS Electrical Sensors CMOS Optical Sensors Bioanalytical instruments have been miniaturized on ICs to study various biophenomena or to actuate biosystems. These bio-lab-on-IC systems utilize the IC to facilitate faster, repeatable, and standardized biological experiments at low cost with a small volume of biological sample. CMOS Biotechnology will interest electrical engineers, bioengineers, biophysicists as well as researchers in MEMS, bioMEMS, microelectronics, microfluidics, and circuits and systems."
Computational and Ambient Intelligence ; 9th International Work-Conference on Artificial Neural Networks, IWANN 2007, San Sebastián, Spain, June 20-22, 2007, Proceedings
This biennial meeting focuses on the foundations, theory, models and applications of systems inspired by nature (neural networks, fuzzy logic and evo- tionary systems).These new computational techniques are used in applications that try to bring a new situation of well-being to the user. The conjunction of a more and more miniaturized hardware together with the growing computational intelligence embodied in this hardware leads us towards fully integrated embedded systems-on- chip and opens the door for truly ubiquitous electronics.
BioMEMS and biomedical nanotechnology ; Vol. II : Micro/Nano Technologies for Genomics and Proteomics
Numerous miniaturized DNA microarray, DNA chip, Lab on a Chip and biosensor devices have been developed and commercialized. Such devices are improving the way many impor-tant genomic and proteomic analyses are performed in both research and clinical diagnostic laboratories. The development of these technologies was enabled by a synergistic combina-tion of disciplines that include microfabrication, microfluidics, MEMS, organic chemistry and molecular biology. Some of these new devices and technologies utilize sophisticated mi-crofabrication processes developed by the semiconductor industry.
Attention in Cognitive Systems : Theories and Systems from an Interdisciplinary Viewpoint ; 4th International Workshop on Attention in Cognitive Systems, WAPCV 2007 Hyderabad, India, January 8, 2007 Revised Selected Papers
The embodied nature of sensory-motor intelligence requires a continuous and focused interplay between the control of motor activities and the interpretation of feedback from perceptual modalities. Decision making about the selection of information from the incoming sensory stream – in tune with contextual processing on a current task and an agent’s global objectives – becomes a further challenging issue in attentional control. Attention must operate at interfaces between bottom-up driven world int- pretation and top-down driven information selection, thus acting at the core of arti?cial cognitive systems. These insights have already induced changes in AI-related disciplines, such as the design of behavior-based robot control and the computational modeling of animats. Today, the development of enabling technologiessuch as autonomous robotic systems,miniaturizedmobile–evenwearable–sensors,andambientintelligence systems involves the real-time analysis of enormous quantities of data. These data have to be processed in an intelligent way to provide “on time delivery” of the required relevant information. Knowledge has to be applied about what needs to be attended to, and when, and what to do in a meaningful sequence, in correspondence with visual feedback.
Antibody-drug conjugates and cellular metabolic dynamics
Summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs.
