الصفحة 1
الصفحة 1
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Antioxidants effects in health : The bright and the dark side ; 1st ed.

Examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants’ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.

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Bioactive Heterocycles V

This volume contains 10 chapters. The contributions are from researchers famous in their respective fields and the chapters contain high quality reviews on topics related to the chemo-biological studies of several different heterocyclic groups. The first chapter from Saracoglu reviews the functionalization of indoles and the pyrroles via Michael additions, as these compounds have potential for their biological activities. In second chapter Men ́endez reviews the chemistry of the welwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis and recent strategies for the synthesis of lignans.

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