تحسين النتائح
ترتيب حسب
من
الى
الصفحة 1
الصفحة 1
Lymphocyte Trafficking in Health and Disease
Since the discovery of chemokines and of chemokine receptors it has become evident that expression of chemokines at the site of inflammation may regulate the composition of cellular infiltrate, thereby directing the type of immune response. Recently, the molecular characterization of inherited disorders of immune system, (e.g., Wiskott-Aldrich syndrome, WHIM syndrome, leukocyte adhesion deficiency), which are characterized by cytoskeleton/adhesion defects or by altered response of chemokine receptors has contributed to clarifying the key players of immune response in normal physiology and in disease. This book, which deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention, offers a series of contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease.
KRAS : Methods and protocols
Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.
Checkpoint Responses in Cancer Therapy
This book’s distinguished panel of authors takes a close look at topics ranging from the major molecular players affecting DNA synthesis and the response to DNA damage to advances made in the identification of chemical compounds capable of inhibiting individual mitotic kinases. Illuminating and authoritative, Checkpoint Responses in Cancer Therapy offers a critical summary of findings for researchers in the pharmaceutical and biotechnology industries and a valuable resource for academic scientists in cancer research and the study of cell-cycle regulation, signal transduction and apoptosis.
Cancer du sein avancé : 29es Journées de la Société Française de Sénologie et Pathologie Mammaire (SFSPM) Avignon, 14–16 novembre 2007 = Advanced breast cancer : 29th Days of the French Society of Senology and Breast Pathology (SFSPM) Avignon, November 14–16, 2007
These days are an opportunity to remind and persuade those less convinced that the treatment of this very particular phase of the disease is not limited to a score played by a few speakers or even by medical oncologists alone; but on the contrary, we must bring into play a truly philharmonic polyphonic ensemble, united around the patient and comprising all the players in multidisciplinary care: general practitioner, surgeon, radiotherapist, imaging specialist, gynecologist, general practitioner, psychologist, algologist, supportive care workers ...
Bio-Applications of Nanoparticles
In this edited book, we highlight the central players in the Bionanotechnology field, which are the nanostructures and biomolecules. The book starts by describing how nanostructures are synthesized and by describing the wide variety of nanostructures available for biological research and applications. Also shown are the techniques used to synthesize a wide variety of biological molecules. Next, there is a focus on the assembly of nanostructures with biological molecules, which could lead to the design of multi-functional nanosystems. In the following chapters, examples of the unique properties of nanostructures are provided along with the current applications of these nanostructures in biology and medicine. Some applications include the use of gold nanoparticles in diagnostic applications, quantum dots and silica nanoparticles for imaging, and liposomes for drug delivery. In the final chapters of the book, the toxicity of nanostructures are described. This book provides broad examples of current developments in Bionanotechnology research and would be an excellent introduction to the field.
Macroscopic Transport Equations for Rarefied Gas Flows : Approximation Methods in Kinetic Theory
This book discusses classical and modern methods to derive macroscopic transport equations for rarefied gases from the Boltzmann equation, for small and moderate Knudsen numbers, i.e.as well as the new order of magnitude method, which avoids the short-comings of the classical methods, but retains their benefits.
Beginning GIMP : From novice to professional
Beginning GIMP: From Novice to Professional explains how to use the open source image manipulation program, GIMP version 2.4. You'll learn how to install GIMP on Windows, Linux, and MacOS X platforms. Once you've installed the application, you'll learn about the interface and configuration options, and then jump into a quick–and–simple project to familiarize yourself even further. With four–color graphics and screenshots throughout, you'll learn how to prepare camera images for display on web pagesincluding functions like rescaling, cropping, and balancing color. The book also explains with great detail how to utilize layers, paths, and masks. You'll also learn how to draw lines and shapes, use patterns and gradients, and even create your own brushes, patterns, and gradients.
AutoCAD 2006 VBA : A programmer's reference
This book will help you take full advantage of the Visual Basic for Applications programming environment within AutoCAD 2006. Whether you want to automate routine tasks, or create sophisticated applications or design that can be generated programmatically, this book will empower you to make AutoCAD work for you. This book is also suitable if you're a power user who wants to make use of the advanced features of AutoCAD 2006 VBA, and you need a fast reference for the full AutoCAD object model. You'll learn to run Autodesk design tasks in the embedded VBA environment. This book is loaded with source code examples, and gives you no matter your skill level the necessary tools to accomplish your AutoCAD 2006 automation tasks.
Adobe Illustrator Classroom in a Book
Adobe Illustrator Classroom in a Book (2023 release) uses real-world, project-based learning to cover the basics and beyond, providing countless tips and techniques to help you become more productive with the program. For beginners and experienced users alike, you can follow the book from start to finish or choose only those lessons that interest you. Learn to create artwork, from precise drawings to stylistic paintings. Make logos, illustrations, posters, podcast covers, flyers, and more. Explore selections, shapes, and color, progress to freeform gradients and layers. Work with dynamic symbols, artistic brushes, and creative effects.
Barcelona : urban architecture and community since 2010
Highlights some of the most exciting structures built in Barcelona since 2010, bringing readers on a guided tour of surprising residential buildings, intriguing museums and extraordinary community spaces. The projects, including many additions to existing buildings, are documented with photos, floor plans and texts. Supplementary interviews introduce readers to key players in Barcelona’s architectural scene, while essays shed light on little-known aspects of the city’s urban development and transport planning.
Magnetic Heterostructures : Advances and Perspectives in Spinstructures and Spintransport
Magnetic heterostructures constitute an important field in magnetism and nanotechnology, which has developed over the past fifteen years due to important advances in epitaxial- growth techniques and lithographic processes. Magnetic heterostructures combine different physical properties which do not exist in nature. Examples are semiconductors/ferromagnets, superconductors/ferromagnets, and ferromagnets/antiferromagnets. These combinations display rich and novel physical properties different from those that exit in any single one of them. Interlayer exchange coupling, exchange bias, proximity effects, giant magneto-resistance, tunneling magneto-resistance, spininjection and spintransport are examples of new physical phenomena that rely on the combination of different materials layers
Layered Double Hydroxides
Both experimental and theoretical studies of nearly every aspect of the LDH structure are discussed, including the range of metal cations and interlayer anions, M 3+ /M 2+ ratios, LDH polytypes, arrangement of the "interlayer" anions and water molecules, molecular modeling and molecular dynamics simulations, and the long- and short-range order in both the layers and interlayer galleries. Of especial value is the treatment of the more detailed aspects of the LDH structure that are still unresolved.
Complications and quandaries in the ICT sector : Standard essential patents and competition issues
Talks about how the regulatory agencies and courts in the United States, European Union and India are dealing with the rising allegations of anti-competitive behaviour by standard essential patent (SEP) holders. It also discusses the role of standards setting organizations / standards developing organizations (SSO/SDO) and the various players involved in implementing the standards that influence practices and internal dynamics in the ICT sector. The book includes discussions on fair, reasonable and non-discriminatory (FRAND) licensing terms and the complexities that arise when both licensors and licensees of SEPs differ on what they mean by “fair”, “reasonable” and “non-discriminatory” terms. It also addresses topics such as the appropriate royalty base, calculation of FRAND rates and concerns related to FRAND commitments and the role of Federal Trade Commission (FTC) in collaborative standard setting process.
Complexity in chemistry, biology, and ecology
This book, written by an international team of experts, introduces the reader to various aspects of complexity theory and its applications. It illustrates the latest trends in science to go beyond the mechanistic Newtonian view of the world by shifting the focus to self-organization, adaptation, and emergent phenomena. The authors discuss these properties of complex systems in biology, ecology and chemistry along with the structure and interconnectedness of the "layers" of complexity. The qualitative description is complemented by a discussion of methods for complexity quantification. Networks are covered in detail as a universal language of the complex world.
Atmospheric Boundary Layers : Nature, Theory, and Application to Environmental Modelling and Security
This collection of peer reviewed papers represents a concise, up-to-date summary of our current knowledge of planetary boundary layer (PBL) physics and parameterization. As such, it makes a major contribution to the interchange of knowledge and ideas between physicists, meteorologists and environmental modellers and sets out the course to be followed in subsequent research to improve PBL parameterizations in climate, numerical weather prediction, air quality, and emergency preparedness models. Major themes covered are: Nature and theory of turbulent boundary layers, Boundary layer flows - modelling and applications to environmental security, Nature, theory and modelling of boundary-layer flows, and Air flows within and above urban and other complex canopies - air-sea-ice interactions.
Asymptotic Analysis and Boundary Layers
Presents a new method of asymptotic analysis of boundary-layer problems, the Successive Complementary Expansion Method (SCEM). The first part is devoted to a general comprehensive presentation of the tools of asymptotic analysis. It gives the keys to understand a boundary-layer problem and explains the methods to construct an approximation. The second part is devoted to SCEM and its applications in fluid mechanics, including external and internal flows. The advantages of SCEM are discussed in comparison with the standard Method of Matched Asymptotic Expansions. In particular, for the first time, the theory of Interactive Boundary Layer is fully justified. With its chapter summaries, detailed derivations of results, discussed examples and fully worked out problems and solutions, the book is self-contained.
Asian century … on a knife-edge : A 360 degree analysis of Asia's recent economic development
This book delves into the widely held belief that the 21st century will be the "Asian Century" by examining the Asia's rapid economic development in the post-war era and the challenges it faces in forging ahead of world leaders in the West. The impact of the current turbulent global political climate on Asia is critically analyzed, employing a holistic and multidisciplinary approach, combining economic, social, political and geopolitical perspectives. Written in an accessible style, the book offers students, business, government, and civil society players powerful insights on Asia.
Applying fuzzy mathematics to formal models in comparative politics
This book explores the intersection of fuzzy mathematics and the spatial modeling of preferences in political science. This book develops single- and multidimensional models of fuzzy preference landscapes and characterizes the surprisingly high levels of stability that emerge from interactions between players operating.
An Introduction to Global Spectral Modeling
Numerical weather prediction is receiving increased attention as weather forecasters aim to improve the numerical models used to forecast the weather. This is a textbook on global spectral modeling, which is an important component for global weather forecasts at numerous operational centers. This book covers all areas of model development including numerical analysis, treatment of clouds, mountains, radiation, precipitation processes, and the surface layers over land and the ocean. The objectives of this book are to provide a systematic and sequential background for students, researchers, and operational weather forecasters in order to develop comprehensive weather forecast models. This is designed for a one semester introductory graduate level course on weather prediction methodologies. As a prerequisite it requires a basic background in meteorology, applied mathematics, and numerical analysis.
Advances in solid state physics ; Vol. 47
The present volume 47 of the Advances in Solid State Physics contains the written version of a large number of the invited talks of the 2007 Spring Meeting of the Arbeitskreis Festkörperphysik which was held in Regensburg, Germany, from March 26 to 30, 2007 in conjunction with the 71st Annual Meeting of the Deutsche Physikalische Gesellschaft.It gives an overview of the present status of solid state physics where low-dimensional systems such as quantum dots and quantum wires are dominating. The importance of magnetic materials is reflected by the large number of contributions in the part dealing with ferromagnetic films and particles. One of the most exciting achievements of the last couple of years is the successful application of electrical contacts to and the investigation of single layers of graphene.
