الصفحة 1
الصفحة 1
Intelligent drugs : How AI is transforming healthcare
The progress of biotechnologies and artificial intelligence allowed the development of vaccines in less than a year, thus saving millions of human lives and preserving the global economy. The emergence of intelligent drugs is highlighted, with the promise of ultra-targeted, more effective, and safer treatments against a wide range of diseases. Personalized medicine then becomes realistic, with computer-designed drugs, perfectly adapted to each individual, tested on virtual patients before their real use. In the near future, thanks to AI, new drugs will improve physical performance, stimulate cognitive abilities, prevent diseases, and slow down aging.
Bigel : An innovative drug delivery system
Bigel is a promising drug delivery system that modifies the pharmacotherapeutic characteristics of knowing active pharmaceutical ingredient (API).It is a mix between hydrogel and organogel (oleogel). The objective of the present work demonstrates the ability of bigel to overcome the disadvan- tages of both types of gels, including the limited ability to cross lipophilic barriers of the skin for hydrogels and the low patient compliance for organogels due to their stickiness and oily residues. Materials andmethods : Carbomer934, PolyvinylpyrrolidoneK 90 and Castor oil where mixed in a high shear mixer using diferent weight percentages of each. Hence,13 for mulations (BG1 to BG13) prepared by simplex mixture design modelis used to study the inuenceofafore- mentioned ingredients on appearance, dynamicviscosity, pH, stability, microscopicstructure of bigel and to understand the chemical interactions between bigel components, Fouriertrans- form infrared (FTIR) analysis will bereported.
