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الصفحة 1
الصفحة 1
Latency Strategies of Herpesviruses
This is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation.
Kaposi Sarcoma Herpesvirus : New Perspectives
Since the identificationof two sequences fromKSHV,wehave learnedmuch about this pathogen as reflected in this book. As it turned out, KSHV itself encodes for a number of cytokines, and induces cellular cytokine secretion, contributing to tumour growth. Moreover, KSHV vFLIP targets the IKKNFκB axis to encourage the inflammatory microenvironment observed by Gallo and his colleagues. KSHV continues to elucidate both mechanisms of viral oncogenesis, and cellular and immune pathways involved in non-viral driven neoplasia.
Common Dermatologic Conditions in Primary Care
This book offers a guide to common dermatologic conditions most often treated by primary care providers. Most dermatologic disorders in the United States are treated by primary care physicians, and yet primary care training programs do not prioritize dermatology. This easy-to-use reference answers that need with practical recommendations for diagnosing and treating these common diseases along with a number of illustrative color images. Throughout, chapters are either organized by population and the dermatologic conditions common to those groups or diseases commonly encountered in primary care. Populations covered include children, pregnant women, and athletes, and common diseases covered include dermatitis, warts, herpes, psoriasis, and some skin cancers.
