الصفحة 1
الصفحة 1
Office Andrology
The investigation and management of male infertility can be a formidable diagnostic challenge to family physicians, urologists, and reproductive specialists alike. In Office Andrology, noted clinical physicians and scientists have joined forces to create a comprehensive resource guide to current diagnostic and treatment options for a broad spectrum of clinical issues relevant to male infertility disorders. Topics covered range from basic sperm biology and male reproductive endocrinology, to immunology, specialized sperm testing, and the genetic background to male infertility. Although emphasis is on the investigation, diagnostic testing, and management of the infertile male, controversial medical and surgical treatment options are also fully discussed. For the reproductive specialist, the text thoughtfully reviews such timely issues as gender selection, human immunodeficiency virus-discordance couples, and posthumous reproduction. Other topics of interest include laboratory accreditation, vasectomy reversal, ethical and legal considerations of donor insemination, optimizing success in a donor insemination program, and strategic therapies for ejaculatory disorders and erectile dysfunction in infertile men.
Numerical Methods for Nonsmooth Dynamical Systems : Applications in Mechanics and Electronics
This book concerns the numerical simulation of dynamical systems whose trajectories may not be differentiable everywhere. They are named nonsmooth dynamical systems. They make an important class of systems, firstly because of the many applications in which nonsmooth models are useful, secondly because they give rise to new problems in various fields of science. Usually nonsmooth dynamical systems are represented as differential inclusions, complementarity systems, evolution variational inequalities, each of these classes being itself split into several subclasses.
Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
Presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.
Neuronal cell death : Methods and protocols
Covers comprehensive methods on ways to assess structural and ultrastructural changes in the mitochondria, cytoskeleton, and microglia using state-of-the-art microscopy techniques including super-resolution imaging, electron microscopy, and ultra-high field MRI. The chapters in this book cover topics such as analysis of neurodegeneration in the post-mortem characterization of preclinical animal models, in vivo modeling in cell death in different model systems and brain organoids, single cell clonal analysis using Mosaic Analysis with Double Markers in genetic mouse models, and genome and proteomic methods for analysis of mRNA dynamics and quantitation of targeted peptides.
Neuroacanthocytosis Syndromes II
Awareness of neuroacanthocytosis disorders has increased significantly in recent years. There have been a number of important developments in the field since the publication of the first volume, Neuroacanthocytosis Syndromes. This book contains the latest research in this area. Recent advances have identified the range of mutations in the causative genes, shedding light on potential phenotypegenotype correlations. Studies of the proteins affected in these disorders have resulted in increased understanding of their functions and distribution. In vitro studies have identified potential protein interactions, which have important implications for pathophysiology. Work on erythrocyte membranes suggests mechanisms for the generation of acanthocytes. Animal models are being generated which will greatly facilitate understanding the role of gene mutations in humans, and provide the foundation for possible therapeutic interventions. In addition, advances in other neurodegenerative disorders, such as Huntington’s and Parkinson’s diseases, have implications for neuroacanthocytosis.
Neuroacanthocytosis Syndromes
Neuroacanthocytosis Syndromes is the first comprehensive review of a field that has not yet received the attention it deserves. Affecting the brain as well as the circulating red cells, these multi-system disorders in the past had often been mistaken for Huntington's disease. Recent breakthroughs have now identified the molecular basis of several of these. This volume grew out of the first international scientific meeting ever devoted to neuroacanthocytosis and provides in-depth information about the state of the art. Its thirty chapters were written by the leading authorities in the field to cover the clinical as well as the basic science perspective, including not only molecular genetics but also experimental pharmacology and cell membrane biology, among others. The book vehemently poses the question of how the membrane deformation of circulating red blood cells relates to degeneration of nerve cells in the brain, the basal ganglia, in particular. It provides a wealth of data that will help to solve an intriguing puzzle and ease the suffering of those affected by one of the neuroacanthocytosis syndromes.
Mezzi di contrasto in ecografia : Applicazioni addominali = Contrast media in ultrasound : Abdominal applications
Lopera presenta unanalisi completa delle applicazioni dei mezzi di contrasto ecografici a livello addominale. La parte introduttiva di natura tecnica presenta la classificazione generale e le proprietà fisiche dei mezzi di contrasto ecografici, nonché una dettagliata classificazione delle tecniche ecografiche contrasto-specifiche; segue una parte speciale che descrive le applicazioni delle microbolle a livello del fegato, della milza e del rene. Vengono quindi presentate le applicazioni speciali e innovative dei mezzi di contrasto ecografici nellambito dei traumi delladdome, della patologia del pancreas, della parete intestinale e dei vasi addominali, e della valutazione del reflusso vescico-ureterale. Infine, viene proposta unanalisi economica relativa allapplicazione dei mezzi di contrasto ecografici nella caratterizzazione delle lesioni focali epatiche. Il libro è principalmente rivolto ai medici impegnati nellattività ecografica quotidiana, particolarmente in ambito internistico, che desiderano ampliare le proprie competenze nel settore dellecografia con mezzo di contrasto
Introduction to Ion Beam Biotechnology
It presents treatment of modern ion beam biotechnology and with respect to applications of ion beam bombardment of living cellular material in the hybrid field of ion beam physics and biology.Key Topics include: – Ion beam formation – Ion implantation fundamentals – Interaction between energetic ions and biological organisms – Reaction processes of ion implanted biological small molecules – Damage and repair of ion-bombarded DNA – Cell damage due to ion bombardment – Biological effects of ion implantation – Fundamentals of ion-bombardment-induced genetic variation – Ion beam mutation breeding of crops – Ion beam mutation breeding of microbes – Ion beam induced gene transfer – Ion beam induced synthesis of organic molecules – Single-ion bombardment mutation of cells
Interactions Between Neurons and Glia in Aging and Disease
The subject material covered by the book is a crucial competitive area with critical implications for human health and will be of key interest to the scientific community. This unique volume will be invaluable not only to those interested in neuroscience, but also cell biology, molecular biology, biochemistry, and pharmaceutical sciences.
Image Analysis and Processing – ICIAP 2005 ; 13th International Conference, Cagliari, Italy, September 6-8, 2005, Proceedings
This volume contains the Proceedings of the 13th International Conference on Image Analysis and Processing (ICIAP 2005), held in Cagliari, Italy, at the conference centre “Centro della Cultura e dei Congressi”, on September 6–8, 2005. ICIAP 2005 was the thirteenth edition of a series of conferences organized every two years by the Italian group of researchersa?liated to the International Association for Pattern Recognition (GIRPR) with the aim to bring together researchers in image processing and pattern recognition from around the world. As for the previous editions, conference topics concerned the theory of image analysis and processing and its classical and Internet-driven applications. The central theme of ICIAP 2005 was “Pattern Recognition in the Internet and Mobile Communications Era”. The interest for such a theme was con?rmed by the large number of papers dealing with it, the special session devoted to pattern recognition for computer network security, and the emphasis of two invited talks on Internet and mobile communication issues. ICIAP 2005 received 217 paper submissions. Fifteen papers were collected into the two special sessions dealing with Pattern Recognition for Computer Network Security and Computer Vision for Augmented Reality and Augmented Environments.
Humanistic foundation of criminal law
Uses humanity-rationality and experience and the freedom of human will as a theoretical perspective to examine the basic framework of criminal law theories constructed by the criminal classic school and the criminal empirical school. The author puts forward the principle of the duality of rationality and experience of humanity and affirms the determinism of human behavior in the ontological sense and the freedom of will in the axiological sense. From this point of view, this book examines the humanistic foundations of crime and punishment, legislation and justice.
Hormones and the brain
Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.
History of Nordic computing ; IFIP WG9.7 ; 1st Working conference on the history of Nordic computing (HiNC1), June 16-18, 2003, Trondheim, Norway
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.
History of Computing and Education 3 (Hce3) ; IFIP 20th World Computer Congress, Proceedings of the Third IFIP Conference on the History of Computing and Education WG 9.7/TC9, History of Computing, September 7–10, 2008, Milano, Italy
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of refereed international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research.
History of computing and education 2 (HCE2) ; IFIP 19th World Computer Congress, WG 9.7, TC 9: History of computing, Proceedings of the 2nd Conference on the history of computing and education, August 21-24, Santiago, Chile
International Federation for Information Processing The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The scope of the series includes: foundations of computer science; software theory and practice; education; computer applications in technology; communication systems; systems modeling and optimization; information systems; computers and society; computer systems technology; security and protection in information processing systems; artificial intelligence; and human-computer interaction. Proceedings and post-proceedings of referred international conferences in computer science and interdisciplinary fields are featured. These results often precede journal publication and represent the most current research. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.
Hirschsprung's Disease and Allied Disorders
Hirschsprung's Disease and Allied Disorders is the third edition of a comprehensive study of the neuronal disorders of the lower gastrointestinal tract in children. Important new studies and progress in research on bowel motility and motility disorders are covered in detail as well as new aspects concerning the embryology, functional anatomy of the enteric nervous system.
Global Computing ; IST/FET International Workshop, GC 2004, Rovereto, Italy, March 9-12, 2004, Revised Selected Papers
This book constitutes the thoroughly refereed post-proceedings of the IST/FET International Workshop on Global Computing, GC 2004, held in Rovereto, Italy in March 2004. The 18 revised full papers presented were carefully selected during two rounds of reviewing and improvement from numerous submissions. Among the topics covered are programming environments, dynamic reconfiguration, resource guarantees, peer-to-peer networks, analysis of systems and resources, resource sharing, and security, as well as foundational calculi for mobility.
Evidence-based positron emission tomography : Summary of recent meta-analyses on PET
This book summarizes the findings of recent evidence-based articles (meta-analyses) on the use of positron emission tomography (PET) for various clinical indications. It is divided into five main sections, starting with an introduction to PET and meta-analysis.
Energy in Africa : Challenges and Opportunities
This open access book presents a picture of the current energy challenges on the African continent (and the Sub-Saharan region in particular) and proposes pathways to an accelerated energy transition. Starting with an analysis of the status quo and the outlook for Africa’s energy demand and energy access, it provides an account of the available resources, including hydrocarbons and renewable energy resources, which are playing an increasingly crucial role. It then moves on to analyze the level of investment required to scale-up Africa’s energy systems, shedding light on the key barriers and elaborating on potential solutions. It also provides a suggestion for improving the effectiveness of EU–Africa cooperation. While mainly intended for policymakers and academics, this book also speaks to a broader audience interested in gaining an overview of the challenges and opportunities of the African energy sector today and in the future.
Dissipative Systems Analysis and Control : Theory and Applications
Dissipative Systems Analysis and Control (second edition) presents a fully revised and expanded treatment of dissipative systems theory, constituting a self-contained, advanced introduction for graduate students, researchers and practising engineers. It examines linear and nonlinear systems with examples of both in each chapter; some infinite-dimensional examples are also included. Throughout, emphasis is placed on the use of the dissipative properties of a system for the design of stable feedback control laws. The theory is substantiated by experimental results and by reference to its application in illustrative physical cases (Lagrangian and Hamiltonian systems and passivity-based and adaptive controllers are covered thoroughly).
