الصفحة 1
الصفحة 1
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Applied pharmacology for the dental hygienist ; 8th ed.

Provides you with an in-depth understanding of the pharmacologic principles needed for safe and effective dental treatment and oral health care. It discusses drug properties and mechanisms of action, dosages, intended effects, interactions, and adverse reactions - both for the medications a patient may already be taking and for the drugs prescribed by the dentist. This new edition has been updated throughout to give you a firm foundation in pharmacology in order to assess and educate patients so they can maintain optimal oral health!

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Marijuana and the Cannabinoids

Although primarily used today as one of the most prevalent illicit leisure drugs, the use of Cannabis sativa L., commonly referred to as marijuana, for medicinal purposes has been reported for more than 5000 years. Marijuana use has been shown to create numerous health problems, and, consequently, the expanding use beyond medical purposes into recreational use (abuse) resulted in control of the drug through international treaties. Much research has been carried out over the past few decades following the identification of the chemical structure of THC.The purpose of Marijuana and the Cannabinoids is to present in a single volume the comprehensive knowledge and experience of renowned researchers and scientists. Each chapter is written independently by an expert in his/her field of endeavor, ranging from the botany, the constituents, the chemistry and pharmacokinetics, the effects and consequences of illicit use on the human body, to the therapeutic potential of the cannabinoids.

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Management of the Addicted Patient in Primary Care

لThe text is logically organized and key information is easily accessible. The introductory section offers the reader important background and rationale for evaluating and treating addiction in primary care. Following a useful presentation of addiction "basics" (i.e., definitions, neurobiology, genetics, and the disease model), the majority of the book focuses on helping the physician gain insight and develop practical skills that can be readily implemented. A wealth of clinical assessment tools is provided, and the underlying psychosocial processes common to all forms of addiction are discussed. Both pharmacologic interventions and nonpharmalogic modalities are clearly outlined. Of particular note are specific cognitive-behavioral and motivational strategies that can be administered in an office-based setting. The role of community-based recovery support systems is considered as well. Since a complete understanding of why and when to refer is critical to the management of this often life-threatening condition, criteria for referral are detailed. Bulleted clinical "pearls" further aid the reader in gaining insight into treating this difficult patient population.

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Malaria: Drugs, Disease and Post-genomic Biology

This volume brings some of the worlds best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two. The opening chapters discuss antimalarials and resistance to them in Africa and Asia. Then there are reviews of the different clinical manifestations of malaria, ranging from uncomplicated infections to severe disease and its complications.

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Magnetic nanoparticles in human health and medicine : Current medical applications and alternative therapy of cancer

Progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery. Focusing on cancer diagnosis and therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine.

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Lantibiotics as alternative therapeutics

Explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.

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La marche de linfirme moteur cérébral enfant et adulte = Gait in children and adults with cerebral palsy

Patients with cerebral palsy (CP) face numerous neuromotor problems related to brain damage, the functional consequences of which, in the early years of life, impact the acquisition of walking. A better understanding of gait and its levels of control, along with refined and quantified clinical analysis in the laboratory, allows for the definition of therapeutic options in collaboration with the patient, their family, and the healthcare team. Managing muscle tone disorders and neuro-orthopedic problems is a daily challenge for patients at all ages. Patients with CP increasingly benefit from new drug therapies, regular adjustments of walking aids and orthotics, and specific rehabilitation, sometimes combined with surgical procedures, whether orthopedic or neurological. This book reviews the evolution of knowledge and practices.

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La fitoterapia in uno sguardo = Phytotherapy at a glance

This volume summarizes notions of phytotherapy; the intent is to offer the doctor essential knowledge so that he can easily prescribe plant products and to stimulate the pharmacist and herbalist to use them in a more rational way.

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Kindling 6

A broad array of themes concerned with research on epilepsy and kindling is covered in the book: Pathogenesis of kindling, including developmental patterns; electrophysiology; anatomy, morphology, and neural circuitry; genes, species, and strains; synaptic pharmacology and neurochemistry ; Behavioral consequences of kindling ; Drugs and interventions against kindling ; Clinical relevance of kindling for our understanding of epilepsy in patients

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Kinase Drug Discovery : Modern Approaches

Kinase inhibition remains an area of significant interest, and growing importance, across academia and the pharmaceutical industry. There are now many marketed drugs that target kinases and a significant number of compounds are currently in various stages of clinical development. This book is a forward-looking analysis of a number of key areas for kinase inhibition in the coming years and builds on the first volume. This includes topics such as screening approaches to target kinases along with different modes of inhibition such as allosteric and covalent. Novel approaches such as macrocyclisation are considered along with how the properties of kinase inhibitors have evolved, including the potential for brain penetration. Recent areas of great importance also covered include cutting edge molecular modelling approaches and the importance of kinase mutations.

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Ketamine for Treatment-Resistant Depression : Neurobiology and Applications

Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics.

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Katzung's basic and clinical pharmacology

The most comprehensive and authoritative pharmacology text --updated with new content and USMLE-style questions Presented in full-color and packed with hundreds of illustrations, Basic and Clinical Pharmacology is the wide-ranging, engaging guide students have counted on for decades. To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, along with case studies that introduce clinical problems. Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information. Updated to reflect the latest research, this sixteenth edition features a new chapter on cannabinoids, USMLE-style questions, new drug tables, and more. Basic and Clinical Pharmacology, Sixteenth Edition features: * 330 full-color illustrations * NEW: 100 drug tables * NEW: 50 USMLE-style questions * NEW: Chapter on cannabinoids * A strong emphasis on drug groups and prototypes * Case studies and chapter-ending summary tables * Organization that reflects the syllabi of pharmacology courses * Descriptions of important new drugs

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Katzung & Trevor's pharmacology : Examination & board review

Excellent Q & A and rationales for course exams and USMLE Step 1. With 1,000+ board-style questions/answers and fully up-to-date content, this is the most popular review in pharmacology. Organized to reflect the syllabi in pharmacology courses, Katzung & Trevor's Pharmacology Exam and Board Review covers all current drugs and retrovirals, immunologic agents, and chemotherapies. Each chapter begins with 20 pages of informative text, followed by questions and answers, and includes concise discussions of the concepts underlying basic principles or specific drug groups. Edited by the world leading figures in pharmacology and medicine, this high-yield text focuses on basic principles, autonomic drugs, cardiovascular-renal drugs, and drugs with actions on smooth muscle, central nervous system drugs, and drugs used to treat chemotherapeutic drugs, and toxicology.

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Computational biology in drug discovery and repurposing

Takes an in-depth look at the emerging and prospective field of computational biology and bioinformatics, which possesses the ability to analyze large accumulated biological data collected from sequence analysis of proteins and genes and cell population with an aim to make new predictions pertaining to drug discovery and new biology. The book explains the basic methodology associated with a bioinformatics and computational approach in drug designing. It then goes on to cover the implementation of computational programming, bioinformatics, pharmacophore modeling, biotechnological techniques, and pharmaceutical chemistry in designing drugs. The major advantage of intervention of computer language or programming is to cut down the number of steps and costs in the field of drug designing, reducing the repeating steps and saving time in screening the potent component for drug or vaccine designin

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Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals

Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals is a comprehensive handbook on all aspects of adverse effects by drugs and chemical substances on the kidneys.

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Clinical microbiology made ridiculously simple

Is a brief, clear, thorough, and updated approach to clinical microbiology, brimming with mnemonics, humor, summary charts, and illustrations. Topics include Ebola, AIDS, flesh-eating bacteria, mad cow disease, hantavirus, anthrax, smallpox, and tuberculosis; the latest antibiotics; pandemic flu, including H7N9; SARS-like coronavirus; hepatitis C treatment options; HIV diagnostics and approved HIV meds; Zika virus; measles; and a new chapter on the latest emerging infectious diseases and drug-resistant bacteria. The major update to this book is the addition of a new chapter on the SARS-COV-2 virus and COVID-19 disease, which delves into the nature of the virus such as infectivity within the body, transmission between individuals, timeline of infectivity, symptoms, risk factors, therapeutics, and vaccines approved for use.

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Clinical biochemistry and drug development : From fundamentals to output

Focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development.

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Clinical applications of mass spectrometry in drug analysis : Methods and protocols

This fully updated volume describes methods and protocols for a number of drugs and toxins in a stepwise manner. Exploring the versatility and flexibility of mass spectrometry, the book covers the advantages of this technology, which typically include elimination of the need for special reagents such as antibodies, increased sensitivity and specificity, and multi-component analysis enabling the screening of tens to hundreds of compounds in a single assay run. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.

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Cleaning validation : Practical compliance approaches for pharmaceutical manufacturing

Timely coverage of cleaning validation for the pharmaceutical industry, a dynamic area in terms of health-based limits. Encourages pharmaceutical manufacturers, and particularly upper management, to meet the challenges of the science-based and riskbased approaches to cleaning validation. Draws on the author’s vast experience in the field of cleaning validation and hazardous materials. Discusses EMA vs. ISPE on Cleaning Limits and revised Risk-MaPP for highly hazardous products in shared facilities. A diverse list of topics from protocol limits for yeasts and molds to cleaning validation for homeopathic drug products.

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Claytons basic pharmacology for nurses

Helps you understand the principles of pharmacology and apply them to nursing practice. Known for its practical application of the nursing process to drugs and disorders, this book explains how to make informed decisions about drug therapy, educate patients, and administer medications. This edition adds new Next Generation NCLEX® (NGN)-style case studies and questions to prepare you for the critical thinking questions on the NGN exam. Concise and easy to use, this text teaches the basics of medication administration and drug actions.

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