تحسين النتائح
ترتيب حسب
من
الى
الصفحة 1
الصفحة 1
Les douleurs abdominales en questions : Rôle physiopathologique de la sensibilité viscérale = Abdominal pain in question : The pathophysiological role of visceral sensitivity
The gut-brain axis refers to the network of nerve pathways that connect the myenteric plexus, the veritable "gut brain," to the central nervous system. Nearly 80% of these neurons are sensory neurons, and the afferent pathways that transmit information from the digestive tract to the central nervous system play a crucial role in the physiological regulation of digestive functions, as well as in certain pathological conditions. A large majority of these sensations remain unconscious and give rise to reflex responses. Only those requiring a conscious response reach the level of awareness in a normal state (hunger, thirst, the urge to defecate). In pathological situations, the same is true for painful sensations of digestive origin. Functional bowel disorders are a frequent reason for consultation. Their pathophysiology is now based on a model integrating the various etiological factors around the brain-gut axis. These patients frequently present with visceral hypersensitivity, which manifests as an increased perception of digestive sensations, notably the onset of pain in response to stimuli that are not painful in normal subjects. Recognizing the role of visceral hypersensitivity has made it possible to explain the mechanism of action of medications used to treat functional bowel disorders and paves the way for the development of new molecules acting on digestive afferents. In this book, we will describe the anatomical and physiological basis for understanding the concept of visceral sensitivity and the role of digestive afferents in the pathophysiology of acute and chronic abdominal pain, particularly irritable bowel syndrome.
Les cancers digestifs = Digestive cancers
Digestive tumors are among the most common malignant tumors and represent a major public health problem. This is one of the areas that has evolved the most in recent years in oncology due to significant progress in diagnostic strategies and therapeutic management. It seems essential that this progress be implemented in the daily practice of physicians treating these tumors. This book, the result of multidisciplinary work, provides a practical and up-to-date approach to the management of malignant digestive tumors. The first chapters are devoted to general and original subjects such as epidemiology, genetics, the management of elderly subjects. A second part approaches in a pragmatic and practical way the principles of diagnostic and therapeutic management by localization. A third part, devoted to the practical realization of chemotherapy, takes stock of new therapeutic approaches, oral or locoregional chemotherapy. Finally, the last part of the book is dedicated to digestive cancer emergencies and the palliative management of these tumors.
