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Open access databases and datasets for drug discovery
With an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free data” available to today’s pharmaceutical researchers. The applicability of open-source data for drug discovery and development is analyzed, and their usefulness in comparison with commercially available tools is evaluated. The most relevant databases for small molecules, drugs and druglike substances, ligand design, protein 3D structures (both experimental and calculated), and human drug targets are described in depth, including practical examples of how to access and work with the data. The first part is focused on databases for small molecules, followed by databases for macromolecular targets and diseases. The final part shows how to integrate various open-source tools into the academic and industrial drug discovery and development process.
Nonparametric Functional Data Analysis : Theory and Practice
Modern apparatuses allow us to collect samples of functional data, mainly curves but also images. On the other hand, nonparametric statistics produces useful tools for standard data exploration. This book links these two fields of modern statistics by explaining how functional data can be studied through parameter-free statistical ideas. This book starts from theoretical foundations including functional nonparametric modeling, description of the mathematical framework, construction of the statistical methods, and statements of their asymptotic behaviors. It proceeds to computational issues including R and S-PLUS routines. Several functional datasets in chemometrics, econometrics, and pattern recognition are used to emphasize the wide scope of nonparametric functional data analysis in applied sciences. The companion Web site includes R and S-PLUS routines, command lines for reproducing examples presented in the book, and the functional datasets. Rather than set application against theory, this book is really an interface of these two features of statistics. A special effort has been made in writing this book to accommodate several levels of reading.
Negotiation agent
Negor is an eCommerce AI chatbot that increases sales by engaging with the user much like a salesperson when you walk into a store. This conversational eCommerce approach allows companies to overcome sales obstacles, recommend products for cross- or up-sells, and reduce support tickets all while being available 24/7. E-commerce is a way to make the customers' buying experience more seamless and interactive while helping to offer bargaining features, which are familiar in traditional stores. In addition, the Chatbot is used to negotiate the best price for the customer and the best deal for the seller.
Model-based Geostatistics
Geostatistics is concerned with estimation and prediction problems for spatially continuous phenomena, using data obtained at a limited number of spatial locations. The name reflects its origins in mineral exploration, but the methods are now used in a wide range of settings including public health and the physical and environmental sciences. Model-based geostatistics refers to the application of general statistical principles of modeling and inference to geostatistical problems. This volume is the first book-length treatment of model-based geostatistics. The authors have written an expository text, emphasizing statistical methods and applications rather than the underlying mathematical theory. Analyses of datasets from a range of scientific contexts feature prominently, and simulations are used to illustrate theoretical results. Readers can reproduce most of the computational results in the book by using the authors' R-based software package, geoR, whose usage is illustrated in a computation section at the end of each chapter.
Mind conversation = التنبؤ بالحروف العربية من خلال الإشارات الدماغية
Throughout history, humans have long dreamed of understanding what goes on inside the human mind—what people are thinking or feeling. It seemed like something from a far-off future or a magical realm. But now, thanks to amazing technology called EEG and BCI, this dream is turning into reality. EEG stands for electroencephalography. It's a way of listening to what the brain is up to by placing small sensors on or near the head. These sensors pick up tiny electrical signals produced by the brain's activity. It's like eavesdropping on the brain's conversations with itself. BCI, or Brain-Computer Interface, is like a bridge between the brain and machines. It lets the brain talk to devices or computers. This means people can control things without using their hands or voices. Our system takes advantage of EEG and BCI to create something helpful, a special mobile app. This app is designed for people who can't move their bodies, like those who are paralyzed. It helps them use their phones to express what they are thinking about.
Methods of microarray data analysis V
In this volume, all investigators analyzed a single dataset on the lifecycle of the most deadly of malaria parasites, Plasmodium falciparum. The emphasis this year is on the application of novel and existing computational methodologies towards infectious disease. We highlight an introductory chapter by Raphael D. Isokpehi, a leading expert in the field of malaria. Ten of the papers presented at the conference are included, which range from the inference of genetic networks to the analysis of the spatial correlation of array data. This book is an excellent reference for academic and industrial researchers who want to keep abreast of the state-of-the-art in microarray data analysis.
MATLAB® Recipes for Earth Sciences
MATLAB® is used in a wide range of applications in geosciences, such as image processing in remote sensing, generation and processing of digital elevation models and the analysis of time series. This book introduces methods of data analysis in geosciences using MATLAB such as basic statistics for univariate, bivariate and multivariate datasets, jackknife and bootstrap resampling schemes, processing of digital elevation models, gridding and contouring, geostatistics and kriging, processing and georeferencing of satellite images, digitizing from the screen, linear and nonlinear time-series analysis and the application of linear time-invariant and adaptive filters. The revised and updated Second Edition includes new subchapters on windowed Blackman-Tukey, Lomb-Scargle and Wavelet powerspectral analysis, statistical analysis of point distributions and digital elevation models, and a full new chapter on the statistical analysis of directional data. The text includes a brief description of each method and numerous examples demonstrating how MATLAB can be used on data sets from earth sciences. All MATLAB recipes can be easily modified in order to analyse the reader's own data sets.
Intelleger = انتليجر
The project management system is a web application designed to assist software managers in efficiently managing their projects, including websites, mobile apps, and other software initiatives. Utilizing artificial intelligence, the application streamlines project creation and management processes, offering significant benefits in terms of organization and accuracy. Managers can create projects by inputting essential details such as the name, scope, deadline, and tasks. The system generates AI-based functional and non-functional requirements tailored to the project scope using gpt2 model on Pure dataset. Managers can then review and edit these requirements as needed before finalizing the project. The application facilitates comprehensive task management by allowing managers to assign tasks to developers, edit task details, and ensure task deadlines align with project deadlines. Developers can log their start and end times automatically when they begin and complete tasks, providing accurate time tracking and performance analysis.also they can use code generation model to generate their task’s code using codebert model on concode and codesearchnet dataset Real-time notifications keep both managers and developers informed of task assignments, completions, and other critical updates.
Innovation and Firm Performance : An Empirical Investigation for German Firms
The process of firms’ growth – in terms of productivity or employment – is a major concern of policy makers. In this context, innovations are considered to play a crucial role in stimulating firms’ performance. This book investigates this general hypothesis by looking at three topics: 1. Does innovation lead to an increase in employment growth? 2. Does innovation boost labour productivity? 3. Does innovation in one period improve innovation performance in subsequent periods? Based on a comprehensive innovation panel dataset for German firms, this book presents detailed results for each question, in particular by separating the effects induced by new products from those induced by the introduction of new production technologies. From a theoretical point of view, amongst others, a new multi-product model has been developed to study employment effects.
Information systems management
Intended for the technical reader who works with large volumes of data. Written by experts in information systems management, the book includes chapters on software development, cloud implementation, networking, and handling large datasets, among other topics. Blockchain and artificial intelligence (AI) are the foundations of automated systems and the authors provide their viewpoints on information management by using these fundamental domains of information technology.
Immune mediators in cancer : Methods and protocols
Provides a comprehensive collection of classic and cutting-edge methodologies as well as bioinformatics and genome-editing approaches that are used to quantify immune mediators and analyze their function and biological activity in cancer cells and tissues. Beginning with a section on the detection of immune mediators in samples, the volume continues with sections covering cytokine bioassays, the expression and regulation of immune mediators in cancer cells, and methods to navigate the enormous datasets created by modern DNA and RNA sequencing and proteomic technology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Hearing faces
Our project aims to aid deaf-mute people by tracking hand movements of the deaf-mute person for word level American Sign Language using WLASL model that include 2D CNN -3D CNN and RNN networks training on WLASL large video dataset, then generating the corresponding text and analyzing the person's facial gestures to generate information related to the tone of voice that is most appropriate to the person's age, gender, and race through MTCNN network algorithm that training on generated dataset by us depending on blending VOXCELEB dataset and VGGFACE dataset .
Healthy Longevity in China : Demographic, Socioeconomic, and Psychological Dimensions
China is aging at an extraordinary speed and has the largest quantity of elderly persons in the world. Scholars utilize this unprecedented living experience of human being and the unique Chinese Longitudinal Healthy Longevity Survey (CLHLS) datasets with the aim to answer in this volume the following questions critical to the aging population world wide. Is the period of disability compressing or expanding with increasing life expectancy and what factors are associated with these trends in the recent decades? Is it possible to realize morbidity compression with a prolongation of the life span in the future?The first section of the book presents the CLHLS project’s study design, sample distribution, contents of data collected, and assessments of age reporting and data quality. The remaining chapters are grouped into sections dealing with the demographic, social, economic, familial and psychological dimensions of healthy longevity.
Graphics of Large Datasets : Visualizing a Million
Graphics are great for exploring data, but how can they be used for looking at the large datasets that are commonplace to-day? This book shows how to look at ways of visualizing large datasets, whether large in numbers of cases or large in numbers of variables or large in both. Data visualization is useful for data cleaning, exploring data, identifying trends and clusters, spotting local patterns, evaluating modeling output, and presenting results. It is essential for exploratory data analysis and data mining. New approaches to graphics are needed to visualize the information in large datasets and most of the innovations described in this book are developments of standard graphics. There are considerable advantages in extending displays which are well-known and well-tried, both in understanding how best to make use of them in your work and in presenting results to others. It should also make the book readily accessible for readers who already have a little experience of drawing statistical graphics. All ideas are illustrated with displays from analyses of real datasets and the authors emphasize the importance of interpreting displays effectively. Graphics should be drawn to convey information and the book includes many insightful examples.
Geospatial Services and Applications for the Internet
This book covers a wide spectrum of techniques, algorithms and modeling methodologies that address the challenges in service-oriented architectural design for GIS, and intelligent processing for spatial queries. This book presents in-depth studies on performance improvement, data integration, service personalization and interoperation between geospatial services. These studies provide the reader with a wide spectrum of examples and case studies on the development of GIS for hydrological applications, electrical power supply applications, land usage and urban planning, and NASA’s Earth image datasets dissemination.
Evolutionary computation, machine learning and data mining in bioinformatics ; 6th European Conference, EvoBIO 2008, Naples, Italy, March 26-28, 2008. Proceedings
The feld of bioinformatics has two main objectives: the creation and main- nance of biological databases, and the discovery of knowledge from life sciences data in order to unravel the mysteries of biological function, leading to new drugs and therapies for human disease. Life sciences data come in the form of biological sequences, structures, pathways, or literature. One major aspect of discovering biological knowledge is to search, predict, or model specifc infortioninagivendatasetinorderto generate new in teresting knowledge.Computer science methods such as evolutionary computation, machine learning, and data mining all have a great deal to ofer the feld of bioinformatics.
Energy minimization methods in computer vision and pattern recognition ; 6th International Conference, EMMCVPR 2007, Ezhou, China, August 27-29, 2007, Proceedings
Contains critical issues of representation, learning, and inference. Important new themes include pr- abilistic grammars, image parsing, and the use of datasets with ground-truth to act as benchmarks for evaluating algorithms and as a way to train learning algorithms. Other themes include the development of efficient inference algorithms using advanced techniques from statistics, computer science, and applied mathematics. This book makes no distinction between oral and poster papers. It also contiants sections on al- rithms, applications, image parsing, image processing, motion, shape, and thr- dimensional processing.
Economic Analyses of the European Patent System
Stefan M. Wagner analyses problems associated with institutional changes (duration of patent examination and opposition mechanisms), the expansion of the patentable subject matter and organizational challenges for industrial patentees. The study is based on the empirical analysis of large scale datasets on European patents and employs advanced multivariate methods such as semi-parametric and panel-data regression methods.
Dream catcher
Dream Catcher is a video generation application that helps in many fields as science fiction, imagine event’s scenarios, education, animation and montage. By applying artificial algorithms implemented and trained on a dataset containing video samples and there descriptions to generate videos from any given text. The idea of generating videos from text is a new idea that was first presented at 2017, even that international companies like Google and OpenAi In the last year, was working on developing models to generate images from text. To make it easier to use the application, there are many ways to enter the text either by an image, voice or Typing from the keyboard.
Deepfake detection = اكتشاف التزييف العميق
In the rapidly evolving era of artificial intelligence, addressing the escalating threats of deepfake technology becomes a necessity because of the increasing sophistication of AI algorithms in generating deceptive content, and since it threatens the integrity of information across diverse data. The main objective is to build a sophisticated AI-driven system to detect different types of deepfake in text, audio, and images. In English text deepfake detection, multiple pre-trained tokenizers have been used, but XLNET and BERT stand out with identifying objects outside the dataset with an accuracy of 0.9809 and both have been generalized & trained using LSTM. In Arabic text deepfake detection, Arabert has been trained using LSTM which led with an accuracy of 99.53% by generalizing the model. Both English and Arabic datasets have been generated to enhance the accuracy and effectiveness of the models. Audio deepfake detection has been generalized too, using Random Forest with an accuracy of 98.259%.
