الصفحة 1
الصفحة 1
NEURO-COVID-19 : Neuroinvasive potential and neurological complications of SARS-CoV-2
From the earliest days of the COVID-19 pandemic, there have been reports of significant neurological and psychological symptoms following SARS-CoV-2 infection. This research paper is designed to examine the potential psychoneuroendocrine pathogenic mechanisms by which SARS-CoV-2 elicits psychiatric sequelae, as well as to posit potential pharmacologic strategies to address and reverse these pathologies. Following a brief overview of the presence and prevalence of neuropsychiatric manifestation in COVID-19 patients, we address mechanisms by which SARS-CoV-2 could enter or otherwise elicit changes in the CNS.
Molecular biology : Structure and dynamics of genomes and proteomes
Illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous, yet still concise, summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system, Coronaviruses – structure, genome, vaccine and drug development, and newly recognized mechanisms for transcription termination.
Impact of COVID-19 on the dental community
The COVID-19 pandemic is considered to be a global public health emergency. Due to its route of transmission via contact with droplets and aerosols, dentists are at high risk of acquiring an infection while treating patients. The impact of the coronavirus on the dental community is eminent, and the greatest challenge is how we can offer dental treatment despite the outbreak. Dental education programs in both under- and postgraduate forms will also suffer from the ramifications of the pandemic. This topical collection offers many perspectives on the management of the COVID-19 crisis within the dental community.
Governing the Pandemic : The politics of navigating a Mega-Crisis
This book offers unique insights into how governments and governing systems, particularly in advanced economies, have responded to the immense challenges of managing the coronavirus pandemic and the ensuing disease COVID-19.
Euro-Par 2020 : Parallel Processing ; 26th International Conference on Parallel and Distributed Computing, Warsaw, Poland, August 24–28, 2020, Proceedings
This book constitutes the proceedings of the 26th International Conference on Parallel and Distributed Computing, Euro-Par 2020, held in Warsaw, Poland, in August 2020. The conference was held virtually due to the coronavirus pandemic. The 39 full papers presented in this volume were carefully reviewed and selected from 158 submissions. They deal with parallel and distributed computing in general, focusing on support tools and environments; performance and power modeling, prediction and evaluation; scheduling and load balancing; high performance architectures and compilers; data management, analytics and machine learning; cluster, cloud and edge computing; theory and algorithms for parallel and distributed processing; parallel and distributed programming, interfaces, and languages; multicore and manycore parallelism; parallel numerical methods and applications; and accelerator computing.
Detection and analysis of SARS Coronavirus : Advanced biosensors for pandemic viruses and related pathogens
The highly contagious SARS CoV-2 pathogen has challenged health systems around the world as they struggle to detect and monitor the spread of the pathogen. In Detection and Analysis of SARS Coronavirus: Advanced Biosensors for Pandemic Viruses and Related Pathogens expert chemists Chaudhery Mustansar Hussain and Sudheesh K. Shukla deliver a practical analysis of how contactless coronavirus detectors may be developed using existing biosensor technology.
COVID-19: Diagnosis and Treatment
The global coronavirus disease 2019 (COVID- 19) has presented major challenges for clinical laboratories, from initial diagnosis to patient monitoring and treatment. Initial response to this pandemic involved the development, production, and distribution of diagnostic molecular assays at an unprecedented rate, leading to minimal validation requirements and concerns regarding their diagnostic accuracy in clinical settings. In addition to molecular testing, serological assays to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now becoming available from numerous diagnostic manufacturers. In both cases, the lack of peer-reviewed data and regulatory oversight, combined with general misconceptions regarding their appropriate use, have highlighted the importance of laboratory professionals in robustly validating and evaluating these assays for appropriate clinical use.
COVID-19 in dentistry and dental education
Dentistry has already been shown to be a hazardous occupation due to the numerous infectious and health risks associated with it. Over the past year and a half, this risk has only grown because of the highly transmissible nature of the Coronavirus. Dentistry, being a profession where the operator and the assistants are in close contact with the patients, has seen numerous changes. Not only this, but even dental education has been impacted as most of the teaching over the pandemic period has been conducted online. Furthermore, dental education has been highly impacted as a major part of it involves hands-on training. Due to this, there are several social, financial, and health-related repercussions that must be analyzed and understood. This Special Issue invited manuscripts, both research and review, that analyze the SARS-CoV-2 situation with regard to dentistry and dental education.
COVID-19 in Alzheimer's disease and dementia
COVID-19 in Alzheimer’s Disease and Dementia crucially summarizes the current status of the coronavirus in patients suffering from these conditions, describing why they are a common cause of morbidity among those with COVID-19. The first section includes chapters that provide a general description of COVID-19, including SARS-CoV-2 structure, function, and biology, and its impact on the elderly with chronic conditions include hypertension, diabetes, obesity, kidney disease, respiratory illnesses, and infectious diseases. Also discussed are effects of the virus on the immune system. The second section shifts to the impact of COVID-19 on those with dementia or Alzheimer’s disease, with special emphasis on age, gender, ethnic background, and lifestyle.
COVID-19 and new aspects of treatment that might lower the risks and mortality rate
Coronaviruses are enveloped non-segmented positive-sense RNA viruses belonging to the family Coronaviridae. The human coronavirus infections are mild; the epidemics of the two βcoronaviruses, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) have caused more than ten thousand cumulative cases in the past two decades. There is a new public health crisis threatening the world with the emergence and spread of 2019 novel coronavirus (2019nCoV). The virus originated in bats and was transmitted to humans through yet unknown intermediary animals in Wuhan, Hubei province in China during the month of December 2019. After the pandemic have started the scientists and researchers started immediately to find ways and technics to diagnose the virus in a different analytical and chemical methods to investigate and find out more about the new species
COVID-19 & Cardiovascular Complications
A highly pathogenic human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently recognized in Wuhan, China, as the cause of the coronavirus disease 2019 (COVID-19) outbreak which has spread rapidly from China to other countries in the world, causing a pandemic with alarming morbidity and mortality. The emerging epidemiological data about COVID-19 patients suggest an association between cardiovascular diseases (CVD) and SARS-CoV-2 infection, in term of clinical features at hospital admission and prognosis for disease severity. The aim of our review is to describe the cardiological features of COVID-19 patients at admission, the acute cardiac presentation, the clinical outcome for patients with underlying CVD and the pharmacological implications for disease management.
Coronaviruses with Special Emphasis on First Insights Concerning SARS
This book series focuses on relevant and trending topics in microbiology and infectious diseases with emphasis on emerging pathogens and related diseases.This interdisciplinary series presents latest advances and new approaches in molecular biology as well as insights into human and veterinary clinical medicine. Furthermore, matters in epidemiology, disease management, hygiene and prevention of infectious diseases are discussed. Emerging or novel pathogens are a grand challenge in medical science. Therefore, we focused the first volume of this series on the outbreak of SARS. The advent of SARS is a threat for people around the globe. Our modern technologies in communication and mobility have figuratively transformed the world into a village. This traffic, however, reprensents a new opportunity to spread diseases, particularly such of infectious nature from tiny villages throughout the entire world. In-depth knowledge of a novel pathogen's characteristics will help to manage or event prevent pandemias.
Coronaviruses : Methods and Protocols
Aims to describe a variety of techniques that reflects the wide range of research currently performed in the field of coronavirology, and begins with an overview of current understandings of coronavirus replication and pathogenesis to introduce specialists and non-specialists to the field. The rest of the book is divided into several sections of chapters beginning with those that describe identification, diagnosis, and study of the evolution of coronaviruses. The next few chapters discuss the preparation of cells and organ cultures useful in propagating coronaviruses and titration techniques, as well as techniques for analyzing virus functions that require purification of the viruses. The next chapters describe two commonly used reverse genetics techniques for coronaviruses, and techniques detailing identification of cellular receptors, binding profiles of viral attachment proteins, and virus-cell fusion. The final chapters cover a broad spectrum of techniques to identify virus-host protein-protein interactions, confirm the functional role of these proteins in virus replication, study host cell responses through genome-wide or pathway-specific approaches, and visualize virus replication complexes. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.
Coronavirus therapeutics ; Vol. II : Clinical management and public health
Provides the most comprehensive review on contemporary knowledge on the consequences during the outbreak of Coronavirus. This also describes the clinical features, diagnostic evaluation and management of Coronavirus patients. Using an integrative approach to the understanding of paradigm gap in host-pathogen interaction studies to the management of Coronavirus patients in the Intensive Care Unit to the current challenges for the effective management of Coronavirus pandemic risk factors including diabetes, hypertension, obesity and repercussion on the central and peripheral nervous system.
Coronavirus therapeutics ; Vol. I : Basic science and therapy development
Provides the most comprehensive review on contemporary knowledge on the origin and structural biology and molecular aspects of Coronaviruses. This also describes the etiology and pathogeny and therapeutic targets including vaccine drug candidates against Coronaviruses in the light of current scientific knowledge. Using an integrative approach to the understanding of Coronaviruses structure, function and immunobiology, the contributors provide a synopsis of novel mechanisms by which Coronaviruses can be treated.
Coronavirus Replication and Reverse Genetics
This book contains information on virus genome structure, mechanism of replication and transcription, and the development of tools that make possible reverse genetic studies to understand virus-host interactions and the molecular basis of virus pathogenesis. The book also provides essential information for the development of classical and recombinant vaccines to control coronavirus infections.
Clinical microbiology made ridiculously simple
Is a brief, clear, thorough, and updated approach to clinical microbiology, brimming with mnemonics, humor, summary charts, and illustrations. Topics include Ebola, AIDS, flesh-eating bacteria, mad cow disease, hantavirus, anthrax, smallpox, and tuberculosis; the latest antibiotics; pandemic flu, including H7N9; SARS-like coronavirus; hepatitis C treatment options; HIV diagnostics and approved HIV meds; Zika virus; measles; and a new chapter on the latest emerging infectious diseases and drug-resistant bacteria. The major update to this book is the addition of a new chapter on the SARS-COV-2 virus and COVID-19 disease, which delves into the nature of the virus such as infectivity within the body, transmission between individuals, timeline of infectivity, symptoms, risk factors, therapeutics, and vaccines approved for use.
Clinical laboratory finding in COVID-19: Diagnosis and prognosis
Coronaviruses belong to a family of viruses that comes under the order “Nidovirales”. This order includes the viruses that use a nested set of mRNAs for their replication. Further, the coronavirus sub-family has four genera (alpha, beta, gamma, and delta coronaviruses). The coronaviruses infecting humans (HCoVs) belong to two of these genera (alpha coronaviruses and beta coronaviruses).
Classification of covid-19 in lung images
The novel coronavirus 2019 (COVID-2019), which first appeared in Wuhan city of China in December 2019, spread rapidly around the world and became a pandemic. It has caused a devastating effect on both daily lives, public health, and the global economy. It is critical to detect the positive cases as early as possible so as to prevent the further spread of this epidemic and to quickly treat affected patients. The need for auxiliary diagnostic tools has increased as there are no accurate automated toolkits available. Recent findings obtained using radiology imaging techniques suggest that such images contain salient information about the COVID-19 virus. Application of advanced artificial intelligence (AI) techniques coupled with radiological imaging can be helpful for the accurate detection of this disease, and can also be assistive to overcome the problem of a lack of specialized physicians in remote villages.
Antiviral drug discovery and development
Summarizes antiviral drug design and discovery approaches Provides the latest update in the field of antiviral therapeutics Includes antiviral research of coronaviruses
