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Computational biology in drug discovery and repurposing
Takes an in-depth look at the emerging and prospective field of computational biology and bioinformatics, which possesses the ability to analyze large accumulated biological data collected from sequence analysis of proteins and genes and cell population with an aim to make new predictions pertaining to drug discovery and new biology. The book explains the basic methodology associated with a bioinformatics and computational approach in drug designing. It then goes on to cover the implementation of computational programming, bioinformatics, pharmacophore modeling, biotechnological techniques, and pharmaceutical chemistry in designing drugs. The major advantage of intervention of computer language or programming is to cut down the number of steps and costs in the field of drug designing, reducing the repeating steps and saving time in screening the potent component for drug or vaccine designin
Biomedical Informatics : Computer Applications in Health Care and Biomedicine
This series is directed to healthcare professionals who are leading the transformation of health care by using information and knowledge. Launched in 1988 as Computers in Health Care, the series offers a broad range of titles: some addressed to specific prof- sions such as nursing, medicine, and health administration; others to special areas of practice such as trauma and radiology.
Mathematical Methods in Computer Science : Essays in Memory of Thomas Beth
This Festschrift volume contains the proceedings of the conference Mathematical Methods in Computer Science, MMICS 2008, which was held during December 17-19, 2008, in Karlsruhe, Germany, in memory of Thomas Beth.The themes of the conference reflected the many interests of Thomas Beth. Although, these interests might seem diverse, mathematical methods and especially algebra as a language constituted the common denominator of all of his scientific achievements.
Mastering Oracle SQL and SQL*Plus
This exceptional book explains fundamentals in detail, supported by realistic examples, while most other books on the market do not properly cover such basics. If you work with relational databases you need to understand the SQL language. And you will gain full competence to define, access, and manipulate data in an Oracle database, if you do so following this book's guidance.
Many-Core Computing : Hardware and software
Provides a timely and coherent account of the recent advances in many-core computing research. Starting with programming models, operating systems and their applications; it presents runtime management techniques, followed by system modelling, verification and testing methods, and architectures and systems. Computing has moved away from a focus on performance-centric serial computation, instead towards energy-efficient parallel computation. This provides continued performance increases without increasing clock frequencies, and overcomes the thermal and power limitations of the dark-silicon era. As the number of parallel cores increases, we transition into the many-core computing era. There is considerable interest in developing methods, tools, architectures and applications to support many-core computing.
Managing Risk and Information Security : Protect to Enable
Examine the evolving enterprise security landscape and discover how to manage and survive risk. While based primarily on the author’s experience and insights at major companies where he has served as CISO and CSPO, the book also includes many examples from other well-known companies and provides guidance for a management-level audience. Managing Risk and Information Security provides thought leadership in the increasingly important area of enterprise information risk and security. It describes the changing risk environment and why a fresh approach to information security is needed. Because almost every aspect of an enterprise is now dependent on technology not only for internal operations but increasing as a part of product or service creation, the focus of IT security must shift from locking down assets to enabling the business while managing and surviving risk. This edition discusses business risk from a broader perspective, including privacy and regulatory considerations. It describes the increasing number of threats and vulnerabilities and offers strategies for developing solutions. These include discussions of how enterprises can take advantage of new and emerging technologies—such as social media and the huge proliferation of Internet-enabled devices—while minimizing risk.
Managing Humans : Biting and Humorous Tales of a Software Engineering Manager
Managing Humans is a selection of the best essays from Michael Lopp's web site, Rands in Repose. Drawing on Lopp's management experiences at Apple, Netscape, Symantec, and Borland, this book is full of stories based on companies in the Silicon Valley where people have been known to yell at each other. It is a place full of dysfunctional bright people who are in an incredible hurry to find the next big thing so they can strike it rich and then do it all over again. Among these people are managers, a strange breed of people who through a mystical organizational ritual have been given power over your future and your bank account.
Managed Software Evolution
This open access book presents the outcomes of the “Design for Future – Managed Software Evolution” .The different lifecycles of software and hardware platforms lead to interoperability problems in such systems. Instead of separating the development, adaptation and evolution of software and its platforms, as well as aspects like operation, monitoring and maintenance, they should all be integrated into one overarching process. Accordingly, the book is split into three major parts, the first of which includes an introduction to the nature of software evolution, followed by an overview of the specific challenges and a general introduction to the case studies used in the project. The second part of the book consists of the main chapters on knowledge carrying software, and cover tacit knowledge in software evolution, continuous design decision support, model-based round-trip engineering for software product lines, performance analysis strategies, maintaining security in software evolution, learning from evolution for evolution, and formal verification of evolutionary changes. In turn, the last part of the book presents key findings and spin-offs. The individual chapters there describe various case studies, along with their benefits, deliverables and the respective lessons learned. An overview of future research topics rounds out the coverage.
Manage IT! : Organizing IT Demand and IT Supply
Discusses the IT management tasks and the objects involved. This book outlines traditional IT management; deals with controlling IT; and, tackles the financial, personnel, purchasing, legal and security aspects in IT. It explains the effects of striving for 'utility computing' and control of IT by means of 'IT portfolio management'.
Machine-learning-assisted intelligent processing and optimization of complex systems
Focuses on the most recent developments in intelligent optimization methods and their applications in various test cases. The reprint covers various topics, including distributed multiagent modeling, metaheuristic algorithms, multisource data fusion, mobile computing and mobile sensing, machine learning-based intelligent processing for modeling complex manufacturing systems, and data-driven intelligent modeling
Machine Learning Techniques and Analytics for Cloud Security
covers new methods, surveys, case studies, and policy with almost all machine learning techniques and analytics for cloud security solutions
Machine learning approach for cloud data analytics in IoT
Covers the multidimensional perspective of machine learning through the perspective of cloud computing and Internet of Things ranging from fundamentals to advanced applications. Elucidates some of the best practices and their respective outcomes in cloud and fog computing environments. It focuses on all the various research issues related to big data storage and analysis, large-scale data processing, knowledge discovery and knowledge management, computational intelligence, data security and privacy, data representation and visualization, and data analytics. The featured technologies presented in the book optimizes various industry processes using business intelligence in engineering and technology. Light is also shed on cloud-based embedded software development practices to integrate complex machines so as to increase productivity and reduce operational costs. The various practices of data science and analytics which are used in all sectors to understand big data and analyze massive data patterns are also detailed in the book.
Machine Learning and Cognitive Computing for Mobile Communications and Wireless Networks
Communication and network technology has witnessed recent rapid development and numerous information services and applications have been developed globally. These technologies have high impact on society and the way people are leading their lives. The advancement in technology has undoubtedly improved the quality of service and user experience yet a lot needs to be still done. Some areas that still need improvement include seamless wide-area coverage, high-capacity hot-spots, low-power massive-connections, low-latency and high-reliability and so on. Thus, it is highly desirable to develop smart technologies for communication to improve the overall services and management of wireless communication. Machine learning and cognitive computing have converged to give some groundbreaking solutions for smart machines. With these two technologies coming together, the machines can acquire the ability to reason similar to the human brain. The research area of machine learning and cognitive computing cover many fields like psychology, biology, signal processing, physics, information theory, mathematics, and statistics that can be used effectively for topology management. Therefore, the utilization of machine learning techniques like data analytics and cognitive power will lead to better performance of communication and wireless systems.
Mac OS X Leopard : Beyond the Manual
Good computer books make assumptions about the reader: what they do and don't know when they pick up the book, and what they want to know when they put it down. For each reader this could be very different; therefore, a book that suits one person may not be the best for another. Mac OS X Leopard: Beyond the Manual makes some assumptions too, ones that tend to differ from other Mac OS X books. First of all, we assume that you have used a computer in that past: that you know how to use a mouse and you know the proper place to stick a DVD to get it to play in your computer. We won't be showing you these things. (We will, however, demonstrate to our Mac converts how to “right click” on a trackpad with only one button!).
Logical Data Modeling : What it is and How to do it
LOGICAL DATA MODELING: What It Is and How To Do IT is directed toward three groups of people: (1) Business subject matter experts, (2) information technology professionals, (3) advanced students in Computer Science, Management Information Systems, and e-Business. Its purpose is to outline the basics of logical data modeling—specifically, data modeling for relational database management systems—in simple, practical terms and in a business context. The focus on relational data modeling is consciously made because it is superior in modeling real business activities.
Logic for Computer Scientists
This book introduces the notions and methods of formal logic from a computer science standpoint, covering propositional logic, predicate logic, and foundations of logic programming. It presents applications and themes of computer science research such as resolution, automated deduction, and logic programming in a rigorous but readable way.The style and scope of the work, rounded out by the inclusion of exercises, make this an excellent textbook for an advanced undergraduate course in logic for computer scientists.
Logging in Java with the JDK 1.4 Logging API and Apache log4j
In development scenarios where things can't be run in a debugger, or when you run the risk of masking the problem, logs are the greatest source of information about running a program. Pro Apache Log4j, Second Edition provides best practices guidelines and comprehensive coverage of the most recent release. Step by step, the book explains core concepts, from basic to advanced. Code samples are in Java and include guidelines for different application-specific needs. You'll also learn how to extend the API to write custom components and best practices for using the feature-rich log4j API. This book concludes with enterprise Java applications using log4j with JSP and J2EE.
LINQ for Visual C# 2008
Every C# programmer needs to learn about LINQ (Language–Integrated Query), Microsoft's breakthrough technology for simplifying and unifying data access from any data source. With LINQ, you can write more elegant and flexible code—not just to access databases and files, but to manipulate data structures and XML. This book is a short, yet comprehensive guide to the major features of LINQ and the significant enhancements introduced with .NET 3.5. There is no better source for getting a head–start on the future of these technologies than this book.
LINQ for Visual C# 2005
LINQ for Visual C# 2005 is a short, yet comprehensive guide to the major features of LINQ. It thoroughly covers LINQ to Objects, LINQ to SQL, LINQ to DataSet, and LINQ to XML. It also details significant enhancements to C#, .NET, and ADO.NET.
LEGO® MINDSTORMS® NXT-G Programming Guide
LEGO MINDSTORMS NXT-G Programming Guide provides programming techniques simple enough to be understood by young programmers, ages 10 and up, and provides a test robot (with instructions) in the appendix for running the programs
