تحسين النتائح
ترتيب حسب
من
الى
الصفحة 1
الصفحة 1
Mammalian Subventricular Zones : Their Roles in Brain Development, Cell Replacement, and Disease
This text provides a comprehensive summary of research and findings that have lead to the current understanding of the subventricular zones. It provides an overview of the roles of subventricular zones in normal development and in disease and a foundation from which current and future studies can be evaluated.
Magnetic Resonance Tomography
Provides a comprehensive overview of both the physics and the clinical applications of MRI, including practical guidelines for imaging. The authors define the importance of MRI in the diagnosis of several disease groups in comparison or combination with other methods.
Magnetic Resonance Imaging in Ischemic Stroke
The imaging of stroke has undergone significant changes owing to the rapid progress in imaging technology. This volume, comprising three parts, is designed to provide a comprehensive summary of the current role of MR imaging in patients with ischemic stroke. The first part outlines the clinical presentations of stroke and discusses the diagnostic efficacy and therapeutic impact of MR imaging. The second and third parts form the core of the volume, and are based on a novel approach in that the topic is presented from two very different viewpoints. Part 2 provides a detailed presentation of the distinguishing features of stroke from the radiologist's perspective. By contrast, part 3 addresses the needs of the clinician, documenting specific stroke syndromes and their correlates on MR imaging. The overall aim has been to create a well-illustrated volume with broad appeal that links pathology, radiology and stroke medicine in an informative manner.
Les douleurs abdominales en questions : Rôle physiopathologique de la sensibilité viscérale = Abdominal pain in question : The pathophysiological role of visceral sensitivity
The gut-brain axis refers to the network of nerve pathways that connect the myenteric plexus, the veritable "gut brain," to the central nervous system. Nearly 80% of these neurons are sensory neurons, and the afferent pathways that transmit information from the digestive tract to the central nervous system play a crucial role in the physiological regulation of digestive functions, as well as in certain pathological conditions. A large majority of these sensations remain unconscious and give rise to reflex responses. Only those requiring a conscious response reach the level of awareness in a normal state (hunger, thirst, the urge to defecate). In pathological situations, the same is true for painful sensations of digestive origin. Functional bowel disorders are a frequent reason for consultation. Their pathophysiology is now based on a model integrating the various etiological factors around the brain-gut axis. These patients frequently present with visceral hypersensitivity, which manifests as an increased perception of digestive sensations, notably the onset of pain in response to stimuli that are not painful in normal subjects. Recognizing the role of visceral hypersensitivity has made it possible to explain the mechanism of action of medications used to treat functional bowel disorders and paves the way for the development of new molecules acting on digestive afferents. In this book, we will describe the anatomical and physiological basis for understanding the concept of visceral sensitivity and the role of digestive afferents in the pathophysiology of acute and chronic abdominal pain, particularly irritable bowel syndrome.
Learning Surgery : The Surgery Clerkship Manual
Provides a ready reference to those in third and fourth year residencies. Essential algorithms and case presentations meet with clerkship learning objectives as outlined by the Association of Surgical Education in their ASE Manual. Two sections include Introduction to Clinical Surgery in the Surgical Clerkship Setting and Management of Surgical Diseases During the Clerkship. Chapters include: Stroke, Hypertension, Abdominal Masses, Head Injuries, and Burns. Written by leading clinicians and educators, both surgery residents and medical students will find LEARNING SURGERY indispensible in their rotations and clerkships. Surgeons who train residents will also find the text a valuable ajunct to their teaching.
La réanimation neurochirurgicale = Neurosurgical resuscitation
«decade of the brain », s’est ajouté en clinique humaine le développement des nouvelles techniques d’imagerie. Ceci a permis d'enterrer enfin certaines idées anciennes et de développer de nouvelles stratégies thérapeutiques fondées sur une meilleure compréhension des mécanismes physiopathologiques de l’agression cérébrale en transposant les résultats de la recherche fondamentale dans la pratique de tous les jours. Il ne fait aucun doute que le médecin, qu'il soit anesthésiste, réanimateur, urgentiste, qui serait passé « à côté » de cette période concernant la prise en charge globale du cerveau agressé se retrouverait distancé face à la prise en charge actuelle et n’aurait pas en main les moyens d’en comprendre sa justification. L’association de neuro-anesthésie réanimation de langue Française
La marche de linfirme moteur cérébral enfant et adulte = Gait in children and adults with cerebral palsy
Patients with cerebral palsy (CP) face numerous neuromotor problems related to brain damage, the functional consequences of which, in the early years of life, impact the acquisition of walking. A better understanding of gait and its levels of control, along with refined and quantified clinical analysis in the laboratory, allows for the definition of therapeutic options in collaboration with the patient, their family, and the healthcare team. Managing muscle tone disorders and neuro-orthopedic problems is a daily challenge for patients at all ages. Patients with CP increasingly benefit from new drug therapies, regular adjustments of walking aids and orthotics, and specific rehabilitation, sometimes combined with surgical procedures, whether orthopedic or neurological. This book reviews the evolution of knowledge and practices.
Kindling 6
A broad array of themes concerned with research on epilepsy and kindling is covered in the book: Pathogenesis of kindling, including developmental patterns; electrophysiology; anatomy, morphology, and neural circuitry; genes, species, and strains; synaptic pharmacology and neurochemistry ; Behavioral consequences of kindling ; Drugs and interventions against kindling ; Clinical relevance of kindling for our understanding of epilepsy in patients
Kinase Drug Discovery : Modern Approaches
Kinase inhibition remains an area of significant interest, and growing importance, across academia and the pharmaceutical industry. There are now many marketed drugs that target kinases and a significant number of compounds are currently in various stages of clinical development. This book is a forward-looking analysis of a number of key areas for kinase inhibition in the coming years and builds on the first volume. This includes topics such as screening approaches to target kinases along with different modes of inhibition such as allosteric and covalent. Novel approaches such as macrocyclisation are considered along with how the properties of kinase inhibitors have evolved, including the potential for brain penetration. Recent areas of great importance also covered include cutting edge molecular modelling approaches and the importance of kinase mutations.
Competence Assessment in Dementia
The increasing proportion of demented elderly in populations, debates over patient's rights and autonomy, and the growing body of knowledge on dementia has inspired the European Dementia Consensus Network to regard competence assessment in dementia as an important topic of debate.
Clinical nuclear medicine
Clinical Nuclear Medicine … focuses on the universal state of the art in both diagnostic and therapeutic radionuclide methodology. … This book is easily readable, with presentation of essential points and plentiful references, and the quality of the figures and tables is excellent. … is a useful guide to students, technologists, and practitioners in nuclear medicine and radiology, as well as to general physicians who request nuclear diagnosis or treatment. … will be a welcome contribution to the bookshelf of nuclear medicine or radiology clinics.
Clinical Neuroembryology : Development and Developmental Disorders of the Human Central Nervous System
Combines data from human embryology, animal research and developmental neuropathology. This book provides an overview of the development of the human Central Nervous System (CNS) in the context of its many developmental disorders due to genetic, environmental and hypoxic causes. It highlights numerous clinical cases and contains over 400 figures.
Clinical MR Imaging : A Practical Approach
This book offers practical guidelines for performing efficient and cost-effective MRI examinations in daily practice. The underlying idea is that, by adopting a practical protocol-based approach, the work-flow in a MRI unit can be streamlined and optimized.
Clinical Functional MRI : Presurgical Functional Neuroimaging
Functional magnetic resonance imaging (fMRI) has contributed significantly to progress in neuroscience by permitting noninvasive imaging of the "human brain at work" under physiological conditions. Within clinical neuroimaging, fMRI is opening up a new diagnostic field by measuring and visualizing brain function. However, fMRI is not yet a standard diagnostic imaging procedure. This textbook is devoted to preoperative fMRI in patients with brain tumors and epilepsies, which are the most well-established clinical applications. By localizing and lateralizing specific brain functions in individual patients, as well as epileptogenic zones, fMRI facilitates the selection of a safe treatment and the planning and performance of function-preserving neurosurgery.
Classic Papers in Critical Care
Every medical specialty has at its basis a core of classic papers, which both reflect the historical background and give insight into present and future developments. The papers discussed in this book are considered classics for many reasons, but in all cases they highlight landmarks in the development in critical care medicine and therefore providing an invaluable reference for both trainee and practising clinicians.
Cilia : Methods and protocols
Covers the latest advancements in the study of ciliary complexity. Protocols cover genomic, proteomic, imaging, and functional analysis of different ciliated tissues and their wide applicability in cilia biology. Chapters in this book primarily focus on methods to study multiciliated cells, and discuss topics such as SARS-CoV-2 infections of human primary nasal multiciliated epithelial cells; expansion microscopy of ciliary proteins; live-imaging centriole amplification in mouse brain multiciliated cells; biophysical properties of cilia motility; and mucociliary transport device construction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Chemical Biology of Neurodegeneration : A Molecular Approach
This book focuses on the main actors involved in neurodegenerative disorders at a molecular level, and places special emphasis on structural aspects and modes of action. Drawing on recent data on enzyme structure, mode of action, and inhibitor design, it describes?from a biochemical point of view?the six most important neurotransmitter systems and their constituent enzymes and receptors. Misfolding and aggregation of proteins within the brain is also covered.
Changing Aspects in Stroke Surgery : Aneurysms, Dissections, Moyamoya Angiopathy and EC-IC Bypass
What is arterial dissection? What is Moyamoya angiopathy? What is the state of art of AVM treatment? Readers will find answers to these questions in this book. But they will also be informed about the state of the art treatment in the daily stroke therapy.
Cerebral vasospasm : New strategies in research and treatment
More than 90 papers give a summary of clinical and basic studies on cerebral vasospasm, including reviews by leading researchers in this field. Several new frontiers are proposed for future research directions that will not only promote research from neurosurgery and neurology but also from other interconnecting fields of emergency medicine, electrophysiology, molecular biology, and vascular biology.
Cerebral monitoring in the OR and ICU
This comprehensive volume will serve as a complete guide to the clinical application of computer assisted systems in monitoring central nervous functions both in the OR and ICU. It presents practical guidelines and therapeutic indications for computerized EEG and Somatosensory Evoked Potential (SSEP) monitoring for the experienced user and the novice. The book also describes what cerebral monitoring can do and what its limitations are.
