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الصفحة 1
الصفحة 1
Malignant Mesothelioma : Pathogenesis, Diagnosis, and Translational Therapies
(Review from JAMA) Malignant mesothelioma is an uncommon neoplasm usually associated with exposure to asbestos. Because of its low incidence, thorough reviews of the topic are hard to find. Harvey Pass and colleagues have edited an up-to-date, comprehensive book that includes a wide range of information, from a historical perspective to descriptions of the latest treatment. The authors . . . have written chapters on the carcinogenesis, molecular genetics, and clinical aspects of mesothelioma. Malignant Mesothelioma is suitable for a broad audience. Laboratory researchers will use it as a resource for information about the pathogenesis, animal models, molecular genetics, and cell lines of mesothelioma. . . . Clinicians will benefit from this complete guide to the presentation, prognosis, imaging, and treatment of the disease. I highly recommend this book to all who are interested in mesothelioma.
La marche de linfirme moteur cérébral enfant et adulte = Gait in children and adults with cerebral palsy
Patients with cerebral palsy (CP) face numerous neuromotor problems related to brain damage, the functional consequences of which, in the early years of life, impact the acquisition of walking. A better understanding of gait and its levels of control, along with refined and quantified clinical analysis in the laboratory, allows for the definition of therapeutic options in collaboration with the patient, their family, and the healthcare team. Managing muscle tone disorders and neuro-orthopedic problems is a daily challenge for patients at all ages. Patients with CP increasingly benefit from new drug therapies, regular adjustments of walking aids and orthotics, and specific rehabilitation, sometimes combined with surgical procedures, whether orthopedic or neurological. This book reviews the evolution of knowledge and practices.
La lombalgie en 2007 : Aspects pratiques = Low back pain in 2007 : Practical aspects
Low back pain is one of the main reasons for consultation, whether in general or specialized medicine. It poses a real public health problem. This "back pain", which can despair patients and doctors by its sometimes rebellious character, explains the multiplicity of examinations sometimes practiced and the treatments implemented. This work is a collection of the most recent developments in terms of physiopathological knowledge of disc involvement, clinical examination and the place of surgery and in particular disc prostheses. An update concerns the indications and contributions of additional examinations; some formidable diagnostic traps are mentioned. Medical treatments such as infiltrations, manipulations, the benefit of restraints and the provision of acupuncture are being developed. Also discussed are the latest scientific data on isokinetic evaluation and retraining, as well as the role of sports activity as a factor in the prevention or aggravation of low back pain. Finally, the medico-legal aspect is dealt with in the context of work accidents, and the assessment after trauma. This book is the result of the collaboration and experience of undisputed specialists in this field.
Keto cookbook for dummies
Millions of people have already benefited from the low-carb ketogenic diet. They’ve lost weight, increased their energy levels, got their Type 2 diabetes under control, and so much more. And if you’re looking for an easy and fun way to get started with keto. n this book, you’ll find 150 delicious keto recipes, from cheesy egg casserole to a keto-inspired berry cobbler. You’ll also discover expert tips on meal planning and preventing common ailments with simple adjustments to your diet. You’ll even learn how to use your Instant Pot and air fryer to make full-flavor, low-carb keto dishes.
Clinical Cardiac MRI
MRI has become the preferred noninvasive imaging modality for the heart and great vessels. The substantial technological progress achieved in recent years has provided the user with state of the art MRI systems, but their optimal use can be limited by restricted awareness of the potential patient benefit and the necessity for teaching. This extensively illustrated volume, has been specifically compiled to meet these needs. Essential theoretical background information is provided, and imaging acquisition and potential pitfalls are considered in detail. Most importantly, structured guidelines are provided on the interpretation of clinical data in the wide range of cardiac pathology that can be encountered. Throughout, the emphasis is on the implementation of cardiac MRI in clinical practice.
Chemistry of natural products : phytochemistry and pharmacognosy of medicinal plants
Plants produce secondary metabolites that humans harness for their own benefit. About half of drugs currently in clinical use are based on these chemicals found in nature. Chemistry of Natural Products covers secondary metabolites present in medicinal plants and their biosynthesis, biological activities, and isolation and separation techniques.
Chemical Leasing Goes Global : Selling Services Instead of Barrels : A Win-Win Business Model for Environment and Industry
Chemical Leasing is an innovative business model within the sustainable management of chemicals. The economic benefit is achieved by selling chemicals services instead of increasing the sales volume. This book contains detailed descriptions and evaluations based on existing projects in Austria, Egypt, Russia and Mexico where in a broard range of sectors and companies the application of Chemical leasing was assisted. The book also contains political and scientific interpretations and analyses.
Cardiac drug therapy
Cardiac Drug Therapy, 7th ed., addresses the pharmacology and therapeutic application of drugs used to treat heart diseases and hypertension. Additions and updates to the sixth edition include six new chapters on current controversies in cardiac drug therapy such as the beta blocker issue many cardiologists are presently grappling with. The book provides practical advice on how to manage cardiac diseases and addresses the choice of one particular cardiac agent vs. another. In addition to providing core knowledge in cardiovascular therapeutics, the text assists in resolving some of the issues surrounding cardiac drugs. Cardiac Drug Therapy provides practical information including properties, dosage, side effects, potential salutary benefits, and drawbacks on virtually all commercially available cardiac drugs.
Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine
Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.
Cancer du testicule = Testicular cancer
Testicular cancer has benefited from important therapeutic advances radically transforming its prognosis. Recent protocols have led to the development of treatments that maintain therapeutic efficacy while favoring quality of life and minimizing the sequelae (such as fertility disorders) in these often young men. This book discusses the various technical advances both in the field of diagnosis - with the contribution of modern imaging and anatomopathology - and therapy. The place of chemotherapy as well as that of surgery are largely detailed, thus placing the urologist at the heart of the multidisciplinary team taking care of these patients. Quality of life is also discussed by taking into account the impact of the treatment of these tumors on the fertility of these young patients.
Cancer Clinical Trials : Proactive Strategies
The ever-changing regulations for clinical trials and the ethical dilemma of treating cancer patients as subjects have made it ever so difficult for the principal investigators to conduct clinical research, especially when they are often ill-informed of the complex nature of the regulations and over-worked. Therefore, cancer clinical trials are at a critical junction. The objective of this book is to bring the issues of cancer clinical trials into focus so that proactive strategies may be developed to make such trials more user-friendly. Ultimately, the cancer patients will be benefited.
Biotic elicitors: Production, purification, and characterization
Details techniques to study biotic elicitors involved in the field of agriculture for the benefit of the environment and growers. Chapters guide readers through protein, carbohydrate, lipid, glycoprotein and glycolipid components derived from microorganisms and their production, purification, and characterization.
Bio-mechanisms of swimming and flying ; Fluid dynamics, biomimetic robots, and sports science
This book follows "Bio-mechanisms of Animals in Swimming and Flying" published in 2004 including 11 chapters. This time, the book includes 31 chapters on the latest researches into natural autonomous systems and locomotion in both flying and swimming organisms. The area of sports science such as analysis and simulation of human swimming is newly added. The computational frameworks for the modeling, simulation and optimization of animals in swimming and flying demonstrate an important role in the progress of interdisciplinary work in the fields of biology and engineering. An innovative technology is exhibited for the flight of an insect size micro air vehicle. Neuronal science is not only unveiling the locomotion mechanisms of swimming in fish from the aspect of the neuronal activities, but also applied to underwater biomimetic robots. The interdisciplinary works are exhibited in the fields of biology and engineering, yielding real-world benefits in innovative technologies.
Biomarkers as targeted herbal drug discovery : A pharmacological approach to nanomedicines
Looks at the applications of biomarkers as important tools for herbal drug discovery, presenting research on phytoconstituents with advanced nanotechnological applications for healthcare benefits. Herbal drug discovery based on biomarkers is an emerging area in complementary and alternative medicine that has tremendous potential in healthcare. Conventional medications have limited efficacy and high toxicity, whereas herbal drugs are said to provide wide structural diversity that is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents, such as terpenoids, fatty acids, flavonoids and steroids, are well explored in the management and treatment of various disorders in this volume. These agents target various biomarkers such as nitric oxide (NO), cytokines, chemokines, adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic acid. Reviews the literature on inflammatory biomarkers in the treatment of diseases Looks at the development of herbal drug discovery based on biomarkers Explores emerging concepts of nanomedicines for herbal drug delivery Takes an interdisciplinary approach, with application to disciplines related to medical, pharmaceutical, biotechnological, Ayurvedic, Unani and biomedical engineering fields
Biologie und epidemiologie der hormonersatztherapie : Diskussionen zur postmenopausalen gesundheit = Biology and epidemiology of hormone replacement therapy : Discussions on postmenopausal health
The advantages and disadvantages of hormone replacement therapy (HRT) are discussed by a group of experts with regard to the epidemiological evidence. However, the focus of the discussion is the problem of breast cancer risk. Among other things, it is shown that the results derived from epidemiological studies do not coincide with the growth characteristics of these tumors, so that further population studies with the inclusion of pathobiological expertise appear necessary. The benefits and risks of hormone replacement therapy (HRT) are discussed by a group of experts with a view towards the evidence provided by recent epidemiological studies. Although all aspects of HRT indications and contra-indications are reviewed, the particular emphasis of this discussion is on breast cancer. Among other things, it is shown that the evidence on breast cancer provided in epidemiological studies does not match the growth characteristics of the tumors, and that further population research incorporating pathobiological assessments is required.
Biological Basis of Geriatric Oncology
Biological Basis of Geriatric Oncology highlights research issues that are specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age. It illustrates the benefit of the principles of geriatrics in the management of cancer in the older individual.
Biofuels and sustainability : Holistic perspectives for policy-making
This open access book presents a comprehensive analysis of biofuel use strategies from an interdisciplinary perspective using sustainability science. This interdisciplinary perspective (social science-natural science) means that the strategies and policy options proposed will have significant impacts on the economy and society alike. Biofuels are expected to contribute to reducing greenhouse gas emissions, revitalizing economies in agricultural communities and alleviating poverty. However, despite these anticipated benefits, international organizations such as the FAO, OECD and UN have published reports expressing concerns that biofuel promotion may lead to deforestation, water pollution and water shortages. The impacts of biofuel use are extensive, cross-sectoral and complex, and as such, comprehensive analyses are required in order to assess the extent to which biofuels can contribute to sustainable societies.
Bee products and their applications in the food and pharmaceutical industries ; 1st ed.
Focuses on the health benefits of selected bee products by looking more closely at their pharmacological potentials and therapeutic applications in coping with various diseases. The book explores some of these products, such as royal jelly, propolis and bee venom, which is highly attractive to the food supplement sector due to the biological actions that are proved by scientific studies. Bee products also attract the cosmetics industry by utilizing those products in various applications such as hair products, toothpaste, sunscreen creams, lip balsams, or facial moisturizing creams. Each chapter focuses on a particular health benefit, providing more compact and detailed information about each activity for a specific interest. The mainframe of the book is based on the medicinal and pharmacological functions of bee products, with the therapeutic applications for each bee product supporting the mechanism of action of their biological functions.
Basiswissen pharmakologie = Basic knowledge of pharmacology
Offers a clear and concise overview of all exam-relevant pharmacology content. It guides you through the entire foundational knowledge, from the basics to the most important clinical pictures, in an easily understandable way and aligned with the German National Competency-Based Learning Objectives for Medicine (GK) and National Competency-Based Learning Objectives for Medicine (NKLM). Benefit from the lecturer's many years of experience, who has carefully selected and presented the essential information for you.
Aromatase Inhibitors
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestrogen synthesis is most readily achieved by inhibiting the final step in the pathway of oestrogen biosynthesis, the reaction which transforms androgens into oestrogens by creating an aromatic ring in the steroid molecule (hence the enzyme's trivial name, aromatase). Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not particularly potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency. Initial results from clinical trials suggest that these agents will become the cornerstones of future endocrine therapy.
