الصفحة 1
الصفحة 1
Open access databases and datasets for drug discovery
With an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free data” available to today’s pharmaceutical researchers. The applicability of open-source data for drug discovery and development is analyzed, and their usefulness in comparison with commercially available tools is evaluated. The most relevant databases for small molecules, drugs and druglike substances, ligand design, protein 3D structures (both experimental and calculated), and human drug targets are described in depth, including practical examples of how to access and work with the data. The first part is focused on databases for small molecules, followed by databases for macromolecular targets and diseases. The final part shows how to integrate various open-source tools into the academic and industrial drug discovery and development process.
Object detection with deep learning models : Principles and applications
Discusses recent advances in object detection and recognition using deep learning methods, which have achieved great success in the field of computer vision and image processing. It provides a systematic and methodical overview of the latest developments in deep learning theory and its applications to computer vision, illustrating them using key topics, including object detection, face analysis, 3D object recognition, and image retrieval / A structured overview of deep learning in object detection / A diversified collection of applications of object detection using deep neural networks / Emphasize agriculture and remote sensing domains / Exclusive discussion on moving object detection
Numerical Methods and Applications ; 6th International Conference, NMA 2006, Borovets, Bulgaria, August 20-24, 2006, Revised Papers
This book constitutes the thoroughly refereed post-proceedings of the 6th International Conference on Numerical Methods and Applications, NMA 2006. The papers are organized in topical sections on numerical methods for hyperbolic problems, robust preconditioning solution methods, Monte Carlo and quasi-Monte Carlo for diverse applications, metaheuristics for optimization problems, uncertain/control systems and reliable numerics, interpolation and quadrature processes, large-scale computations in environmental modelling, and contributed talks.
Numerical Mathematics and Advanced Applications ; Proceedings of ENUMATH 2007, the 7th European Conference on Numerical Mathematics and Advanced Applications, Graz, Austria, September 2007
The European Conference on Numerical Mathematics and Advanced Applications (ENUMATH) is a series of meetings held every two years to provide a forum for discussion on recent aspects of numerical mathematics and their applications. These proceedings contain a selection of invited plenary lectures, papers presented in minisymposia and contributed papers. Topics include theoretical aspects of new numerical techniques and algorithms as well as of applications in engineering and science. The book will be useful for a wide range of readers, giving them an excellent overview of the most modern methods, techniques, algorithms and results in numerical mathematics, scientific computing and their applications.
Numerical Analysis and Its Applications ; 3rd International Conference, NAA 2004, Rousse, Bulgaria, June 29 - July 3, 2004, Revised Selected Papers
Constitutes the refereed post-proceedings of the Third International Conference on Numerical Analysis and Its Applications, held in Bulgaria in June/July 2004. This book addresses various aspects of numerical analysis. It covers the application fields such as computational sciences and engineering, chemistry, physics, economics, and simulation.
Novel Drug Delivery Systems for Chinese Medicines
Describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
Nodal Discontinuous Galerkin Methods : Algorithms, Analysis, and Applications
This book discusses a family of computational methods, known as discontinuous Galerkin methods, for solving partial differential equations. While these methods have been known since the early 1970s, they have experienced an almost explosive growth interest during the last ten to fifteen years, leading both to substantial theoretical developments and the application of these methods to a broad range of problems. These methods are different in nature from standard methods such as finite element or finite difference methods, often presenting a challenge in the transition from theoretical developments to actual implementations and applications.
New Technologies in Radiation Oncology
This book provides an overview of recent advances in radiation oncology, many of which have originated from physics and engineering sciences. After an introductory section on basic aspects of 3D medical imaging, the role of 3D imaging in the context of radiotherapy is explored in a series of chapters on the various modern imaging techniques. A further major section addresses 3D treatment planning for conformal radiotherapy, with consideration of both external radiotherapy and brachytherapy. Subsequently the modern techniques of 3D conformal radiotherapy are described, including stereotactic radiotherapy, intensity-modulated radiation therapy, image-guided and adaptive radiotherapy, and radiotherapy with charged particles. More clinically oriented chapters explore the use of brachytherapy in patients with prostate cancer, cardiovascular disorders and breast cancer. The book concludes with a section on quality assurance.
Neutrophil : Methods and Protocols
Neutrophils, the most abundant white cells in humans, serve as the primary cellular defense against infection. This volume provides a concise set of protocols for assessing basic neutrophil functions and investigating specialized areas in neutrophil biology. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Part I contains overviews of neutrophil biology, function, and disorders. Part II describes commonly used methods to isolate neutrophils from humans and other animal species. Part III details methods for investigating chemotaxis, transmigration, phagocytosis, and bactericidal activity. Part IV includes protocols that measure neutrophil apoptosis, calcium signal transduction, degranulation and detection of cytoplasmic granules, gene expression, transcription factors, and apoptosis. Part V provides multiple assays for measuring production of intracellular and/or extracellular reactive oxygen species, and a method that details use of the cell-free NADPH oxidase assay, an iconic assay for studies of the neutrophil NADPH oxidase. Part VI provides chapters that describe how to analyze formation and function of neutrophil extracellular traps.
Netter's essential histology with correlated histopathology
Concise and easy to use, it integrates gross anatomy and embryology with classic histology slides and state-of-the-art scanning electron microscopy, offering a clear, visual understanding of this complex subject. Additional histopathology images, more clinical boxes, and new histopathology content ensure that this textbook-atlas clearly presents the most indispensable histologic concepts and their clinical relevance. Helps you recognize both normal and diseased structures at the microscopic level with the aid of succinct explanatory text as well as numerous clinical boxes. Features more histopathology content and additional clinical boxes to increase your knowledge of pathophysiology and clinical relevance. Includes high-quality light and electron micrographs, including enhanced and colorized electron micrographs that show ultra-structures in 3D, side by side with classic Netter illustrations that link your knowledge of anatomy and cell biology to what is seen in the micrographs.
Neanderthals Revisited : New Approaches and Perspectives
This volume presents cutting-edge research by leading scientists re-examining the major debates in Neanderthal research with the use of innovative state-of-the art methods and exciting new theoretical approaches.Topics addressed include the re-evaluation of Neanderthal anatomy, inferred adaptations and habitual activities, developmental patterns, phylogenetic relationships, and the Neanderthal extinction; new methods include computer tomography, 3D geometric morphometrics, ancient DNA and bioenergetics. The diverse contributions offer fresh insights and advances in Neanderthal and modern human origins research.
Multimodal Technologies for Perception of Humans ; International Evaluation Workshops CLEAR 2007 and RT 2007, Baltimore, MD, USA, May 8-11, 2007, Revised Selected Papers
This book constitutes the thoroughly refereed joint post-workshop proceedings of two co-located events: the Second International Workshop on Classification of Events, Activities and Relationships, CLEAR 2007, and the 5th Rich Transcription 2007 Meeting Recognition evaluation, RT 2007, held in succession in Baltimore, MD, USA, in May 2007.The workshops had complementary evaluation efforts; CLEAR for the evaluation of human activities, events, and relationships in multiple multimodal data domains; and RT for the evaluation of speech transcription-related technologies from meeting room audio collections.
Multimodal Technologies for Perception of Humans ; 1st International Evaluation Workshop on Classification of Events, Activities and Relationships, CLEAR 2006, Southampton, UK, April 6-7, 2006, Revised Selected Papers
This book constitutes the thoroughly refereed post-proceedings of the First International CLEAR 2006 Evaluation Campaign and Workshop on Classification of Events, Activities and Relationships for evaluation of multimodal technologies for the perception of humans, their activities and interactions. The workshop was held in the UK in April 2006.
Multimodal Intelligent Information Presentation
Intelligent Multimodal Information Presentation relates to the ability of a computer system to automatically produce interactive information presentations, taking into account the specifics about the user, such as needs, interests and knowledge, and engaging in a collaborative interaction that helps the retrieval of relevant information and its understanding on the part of the user.The volume includes descriptions of some of the most representative recent works on Intelligent Information Presentation and a view of the challenges ahead.
Multimedia Content Representation, Classification and Security ; International Workshop, MRCS 2006, Istanbul, Turkey, September 11-13, 2006, Proceedings
This book constitutes the refereed proceedings of the International Workshop on Multimedia Content Representation, Classification and Security, MRCS 2006, held in Istanbul, Turkey in September 2006. The 100 revised papers presented together with 4 invited lectures were carefully reviewed and selected from more than 190 submissions. The papers are organized in topical sections on biometric recognition, multimedia content security, steganography, watermarking, authentication, classification for biometric recognition, digital watermarking, content analysis and representation, 3D object retrieval and classification, representation, analysis and retrieval in cultural heritage, content representation, indexing and retrieval, content analysis and classification, feature extraction and classification, multimodal signal processing, 3D video and free viewpoint video, multimedia content transmission and classification, video and image processing, as well as video analysis and representation.
Multimedia Content Analysis and Mining ; International Workshop, MCAM 2007, Weihai, China, June 30-July 1, 2007, Proceedings
The workshop gives a snapshot of the current wor- wide research in multimedia analysis. Through recent advances in computing, networking, and data storage, multimedia will create new interesting technical possibilities in a wide range of ?elds, such as entertainment, commerce, science, medicine, and public safety.
Multimedia Cartography
The various sections of this book cover the theoretical backgrounds, applications and future developments of Multimedia Cartography. This second edition of Multimedia Cartography includes updated applications areas that are Internet-focussed. Since the release of Edition 1 in 1999 the focus of the delivery of Multimedia Cartography applications now includes the World Wide Web and mobile services, as well as discrete media. New chapters in the book reflect this. As well, the book includes additional chapters on 3D applications and Virtual Reality applications.
MSCs and Innovative Biomaterials in Dentistry
Presents the modern concepts of mesenchymal stem cells (MSCs) and biomaterials as they pertain to the dental field. The book is organized around three main topics: MSCs biology, advanced biomaterials, and clinical applications. The chapters present basic information on stem cell biology and physiology, modern biomaterials that improve bone tissue regeneration, the biomatrices like platelet-rich fibrin (PRF) used to functionalize the biomaterials surface, the strategic and safe intraoral seats of harvesting, the new sources for MSCs, as well as the future perspectives and new challenges in these exciting fields.
Modern construction envelopes
Using current examples by renowned architects, Watts presents the constructive and material-related details. It is based on a text, photos, and standardized detail drawings, as well as 3D representations of the components
Modern Computational Intelligence Methods for the Interpretation of Medical Images
A detailed description of up-to-date methods used for computer processing and interpretation of medical images is given. The scope of the book include images acquisition, storing with compression, processing, analysis, recognition and also its automatic understanding In introduction general overview of the computer vision methods designed for medical images is presented. Next sources of medical images are presented with their general characteristics. Both traditional (like X-ray) and very modern (like PET) sources of medical images are presented. The main emphasis is placed on such properties of medical images given by particular medical imaging methods which are important form the point of view of its computer processing, analysis and recognition.
