الصفحة 99
الصفحة 99
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Introduction to Computational Biology : An Evolutionary Approach

Molecular biology has changed dramatically over the past two decades. Until the early 1990s genes were studied one at a time by small teams of researchers; today entire genomes are sequenced by internationally collaborating laboratories. In the bygone gene-centered era the accumulation of data was the rate-limiting step in research. Now that step is often data interpretation. This is increasingly dependent on computational methods and as a consequence, computational biology has emerged in the past decade as a new subdiscipline of biology. This introduction to computational biology is centered on the analysis of molecular sequence data. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models. In the second part evolutionary time takes center stage and phylogenetic reconstruction, the analysis of sequence variation, and the dynamics of genes in populations are explained in detail. In addition, the book contains a computer program with a graphical user interface that allows the reader to experiment with a number of key concepts developed by the authors.

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Introduction to Complex Analysis in Several Variables

This book gives a comprehensive introduction to complex analysis in several variables. It clearly focusses on special topics in complex analysis rather than trying to encompass as much material as possible. Many cross-references to other parts of mathematics, such as functional analysis or algebras, are pointed out in order to broaden the view and the understanding of the chosen topics. A major focus is extension phenomena alien to the one-dimensional theory, which are expressed in the famous Hartog's Kugelsatz, the theorem of Cartan-Thullen, and Bochner's theorem.

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Introduction to Classical Geometries

This book follows Felix Klein’s proposal of studying geometry by looking at the symmetries (or rigid motions) of the space in question. In this way the classical geometries are studied: Euclidean, affine, elliptic, projective and hyperbolic. For simplicity the focus is on the two-dimensional case, which is already rich enough, though some aspects of the 3- or n-dimensional geometries are included. Once plane geometry is well understood, it is much easier to go into higher dimensions.

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Introduction to Central Banking

This book gives a concise introduction to the practical implementation of monetary policy by modern central banks. It describes the conventional instruments used in advanced economies and the unconventional instruments that have been widely adopted since the financial crisis of 2007–2008. Illuminating the role of central banks in ensuring financial stability and as last resort lenders, it also offers an overview of the international monetary framework. A flow-of-funds framework is used throughout to capture this essential dimension in a consistent and unifying manner, providing a unique and accessible resource on central banking and monetary policy, and its integration with financial stability.

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Introduction to Calculus and Classical Analysis

This text is intended for an honors calculus course or for an introduction to analysis. Involving rigorous analysis, computational dexterity, and a breadth of applications, it is ideal for undergraduate majors. This second edition includes corrections as well as some additional material.The text is completely self-contained and starts with the real number axioms; the integral is defined as the area under the graph, while the area is defined for every subset of the plane; there is a heavy emphasis on computational problems.

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Introduction to C++ Programming and Graphics

Introduction to C++ Programming and Graphics offers a venue for rapidly learning the language by concisely revealing its grammar, syntax and main features, and by explaining the key ideas behind object oriented programming (OOP), with emphasis on scientific computing.

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Introduction to C++ : 500+ Difficulty-Scaled Solved Programming Exercises

Includes more than 500 exercises and examples of progressive difficulty to aid the reader in understanding the C++ principles and to see how concepts can materialize in code. The examples are designed to be short, concrete, and substantial, quickly giving the reader the ability to understand how to apply correctly and efficiently the features of the C++ language and to get a solid programming know-how. Rest assured that if you are able to understand this book's examples and solve the exercises, you can safely go on to edit larger programs, you will be able to develop your own applications, and you will have certainly established a solid fundamental conceptual and practical background to expand your knowledge and skills

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Introduction to built asset management

Introduction to Built Asset Management is a systematic introduction to both the technology and management issues central to building maintenance and refurbishment. Covering the entire life cycle of built assets, the textbook reviews the role of framework agreements, describes key performance indicators, discusses recent advancements in the procurement of maintenance activities and more.

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Introduction to blender 3.0 : Learn organic and architectural modeling, lighting, materials, painting, rendering, and compositing with blender

Explains modeling, materials, lighting, painting, and more with Blender and other external tools. You will configure a 3D architectural environment and set up the workflow of an art and design project within Blender. You will use Blender's main tools—mesh modeling and sculpting—to create virtual objects and environments. And, you will explore building materials and light scenes, followed by drawing and virtual painting. Chapters cover rendering scenes and transforming them into 2D images or videos. You will learn to use Blender 3.0 for video editing as a compositor and video sequence editor (VSE or sequencer) with a wide range of effects available through the nodal system. You Will Learn : Create objects and architectural buildings with different techniques of 3D modeling / Master creating an environment for your objects and how to light them / Determine how to create node materials and assign them to your Blender objects / Pick up UV unwrapping and texture painting / Get closer to painting and drawing in Blender / Render your scenes and create stunning videos

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Introduction to Biosemiotics : The New Biological Synthesis

This book is addressed to students, researchers and academics who have barely heard of the emerging young science of Biosemiotics, and who want to know more about it. Written by many of the field’s major contributors, it provides a highly qualified introduction to Biosemiotics and illustrates the most recent views in its background and development.

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Introduction to biologic and biosimilar product development and analysis

Gives a concise introduction to development and analysis of pharmaceutical biologics for those in the pharmaceutical industry who are switching focus from small molecules to biologics processing, analysis, and delivery. In order to maintain a limited focus, Introduction to Biologic and Biosimilar Product Development and Analysis, will deal only with peptides, proteins and monoclonal antibodies.

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Introduction to Bayesian Statistics

This is the second and translated edition of the German book “Einf ̈uhrung in die Bayes-Statistik, Springer-Verlag, Berlin Heidelberg New York, 2000”. It has been completely revised and numerous new developments are pointed out together with the relevant literature. The Chapter 5.2.4 is extended by the stochastic trace estimation for variance components. The new Chapter 5.2.6 presents the estimation of the regularization parameter of type Tykhonov regularization for inverse problems as the ratio of two variance components.The reconstruction and the smoothing of digital three-dimensional images is demonstrated in the new Chapter 5.3. The Chapter 6.2.1 on importance sampling for the Monte Carlo integration is rewritten to solve a more general integral. This chapter contains also the derivation of the SIR (sampling-importance-resampling) algorithm as an alternative to the rejection method for generating random samples. Markov Chain Monte Carlo methods are now frequently applied in Bayesian statistics.

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Introduction to Bayesian Scientific Computing : Ten Lectures on Subjective Computing

Inverse problems are closely related to statistical inference problems, where the observations are used to infer on an underlying probability distribution. This connection between statistical inference and inverse problems is a central topic of the book. Inverse problems are typically ill-posed: small uncertainties in data may propagate in huge uncertainties in the estimates of the unknowns. To cope with such problems, efficient regularization techniques are developed in the framework of numerical analysis. The counterpart of regularization in the framework of statistical inference is the use prior information.

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Introduction to basics of pharmacology and toxicology ; Vol.3 : Experimental pharmacology : Research methodology and biostatistics

Elaborates on the general principles of experimental pharmacology. Describes about the screening methods for the evaluation of different categories of drugs. Summarizes the various aspects of research methodology and biostatistics.

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Introduction to basics of pharmacology and toxicology ; Vol.2 : Essentials of systemic pharmacology : From principles to practice

Describes the pharmacology of drugs acting on different systems in the human body Analyses various human diseases and the pharmacological agents governing them Provides a valuable reference resource for academicians, researchers, and clinical practitioners Offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics.

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Introduction to basics of pharmacology and toxicology ; Vol.1 : General and molecular pharmacology : Principles of drug action

Illustrates the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases.

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Introduction to Assembly Language Programming : For Pentium and RISC Processors

Assembly language continues to hold a core position in the programming world because of its similar structure to machine language and its very close links to underlying computer-processor architecture and design. These features allow for high processing speed, low memory demands, and the capacity to act directly on the system’s hardware. This completely revised second edition of the highly successful Introduction to Assembly Language Programming introduces readers to assembly language programming and its role in computer programming and design. It focuses on providing a firm grasp of the main features of assembly programming, and how it can be used to improve a computer's performance. The revised edition covers a broad scope of subjects and adds valuable material on protected-mode Pentium programming, MIPS assembly language programming, and use of the NASM and SPIM assemblers for a Linux orientation. All of the language's main features are covered in depth. The book requires only some basic experience with a structured, high-level language.

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Introduction to Applied Optimization

This text presents a multi-disciplined view of optimization, providing students and researchers with a thorough examination of algorithms, methods, and tools from diverse areas of optimization without introducing excessive theoretical detail. This second edition includes additional topics, including global optimization and a real-world case study using important concepts from each chapter.

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Introduction to applied mathematics for environmental science

Introduction to Mathematics for Environmental Science evolved from the author’s 30 years’ experience teaching mathematics to graduate and advanced undergraduate students in the environmental sciences. Its basic purpose is to teach various types of mathematical structures and how they can be applied in a broad range of environmental science subfields. Derivatives and integrals, ordinary and partial differential equations, and linear and non-linear algebraic equations are the basic kinds of structures (types of mathematical models) discussed.

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Introduction to Algorithms

Combines rigor and comprehensiveness. The book covers a broad range of algorithms in depth, yet makes their design and analysis accessible to all levels of readers. Each chapter is relatively self-contained and can be used as a unit of study. The algorithms are described in English and in a pseudocode designed to be readable by anyone who has done a little programming. The explanations have been kept elementary without sacrificing depth of coverage or mathematical rigor. The first edition became a widely used text in universities worldwide as well as the standard reference for professionals. The second edition featured new chapters on the role of algorithms, probabilistic analysis and randomized algorithms, and linear programming.

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