الصفحة 9
الصفحة 9
Malaria: Drugs, Disease and Post-genomic Biology
This volume brings some of the worlds best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two. The opening chapters discuss antimalarials and resistance to them in Africa and Asia. Then there are reviews of the different clinical manifestations of malaria, ranging from uncomplicated infections to severe disease and its complications.
Malaria disease and modern treatments
Some population groups are at considerably higher risk of contracting malaria and developing severe disease: infants, children under 5 years of age, pregnant women and patients with HIV/AIDS, as well as people with low immunity moving to areas with intense malaria transmission such as migrant workers, mobile populations and travellers. Malaria is an acute febrile illness caused by Plasmodium parasites, which are spread to people through the bites of infected female Anopheles mosquitoes. There are 5 parasite species that cause malaria in humans, and 2 of these species – P. falciparum and P. vivax – pose the greatest threat. P. falciparum is the deadliest malaria parasite and the most prevalent on the African continent. P. vivax is the dominant malaria parasite in most countries outside of sub-Saharan Africa.
Malaria : Genetic and Evolutionary Aspects
This book was originally conceived at a conference at the University of Turin in Italy. The conference was organized to examine the so-called “Malaria Hypothesis”, that is to say, the higher fitness of t- lassemia heterozygotes in a malarial environment, and to pay tribute to the proponent of that hypothesis, J.B.S. Haldane. Contributors to this book examine certain genetic and evolutionary aspects of malaria which is a major killer of human populations, especially in Africa and Asia. There were attempts to discredit Haldane’s contribution from two directions: (a) it has been suggested that the “Malaria Hypothesis” was known long before Haldane and that there was nothing original about his idea (Lederberg 1999), and that (b) the hypothesis of heterozygote su- riority was first suggested by the Italian biologist Giuseppe Montalenti who communicated his idea to Haldane (Allison 2004).
Lymphocyte Trafficking in Health and Disease
Since the discovery of chemokines and of chemokine receptors it has become evident that expression of chemokines at the site of inflammation may regulate the composition of cellular infiltrate, thereby directing the type of immune response. Recently, the molecular characterization of inherited disorders of immune system, (e.g., Wiskott-Aldrich syndrome, WHIM syndrome, leukocyte adhesion deficiency), which are characterized by cytoskeleton/adhesion defects or by altered response of chemokine receptors has contributed to clarifying the key players of immune response in normal physiology and in disease. This book, which deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention, offers a series of contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease.
Logistics Systems Analysis
It has two new sections, a new appendix, and more than half a dozen new figures. A few references have also been added, Much of the new material is based on work , The financial support of the National Science Foundation and the Volvo Foundations Center of Excellence for the Future of Urban Transportation at U. C. Berkeley is also acknowledged. The new appendix presents the logic behind the traveling salesman and vehicle routing results used in Sec. 4. 2 to describe the transportation ope- tion; Chapter 4 is more self-contained as a result. New section 5. 6 int- duces and evaluates a general method that automatically translates the c- tinuum approximation recipes of Chapters 4 and 5 into discrete system designs. This closes a gap in previous editions. Other additions include an explanation of how to develop system designs that can efficiently acc- modate real-time control strategies to manage uncertainty (new section 4. 6. 3), and extensions of the many-to-many design ideas of Chap. 6
Logic, language, information and computation ; 15th International Workshop, WoLLIC 2008 Edinburgh, UK, July 1-4, 2008 Proceedings
The papers cover all pertinent subjects in computer science with particular interest in cross-disciplinary topics. Typical areas of interest are: foundations of computing and programming; novel computation models and paradigms; broad notions of proof and belief; formal methods in software and hardware development; logical approach to natural language and reasoning; logics of programs, actions and resources; foundational aspects of information organization, search, flow, sharing, and protection.
Logic, language, information and computation ; 14th International Workshop, WoLLIC 2007, Rio de Janeiro, Brazil, July 2-5, 2007, Proceedings
The Workshop on Logic, Language, Information and Computation (WoLLIC) is an annual international forum on inter-disciplinary research involving formal logic, computing and programming theory, and natural language and reasoning. The WoLLIC meetings alternate between Brazil (and Latin America) and other countries, with the aim of fostering interest in applied logic among Latin Am- ican scientists and students, and facilitating their interaction with the international - plied logic community.
Location Theory : A Unified Approach
Although modern location theory is now more than 90 years old, the focus of researchers in this area has been mainly problem oriented. However, a common theory, which keeps the essential characteristics of classical location models, is still missing. This monograph addresses this issue. A flexible location problem called the Ordered Median Problem (OMP) is introduced. For all three main subareas of location theory (continuous, network and discrete location) structural properties of the OMP are presented and solution approaches provided. Numerous illustrations and examples help the reader to become familiar with this new location model.
Liquidity, markets and trading in action : An interdisciplinary perspective
This book addresses four standard business school subjects: microeconomics, macroeconomics, finance and information systems as they relate to trading, liquidity, and market structure. It provides a detailed examination of the impact of trading costs and other impediments of trading that the authors call “frictions”. It also presents an interactive simulation model of equity market trading, TraderEx, that enables students to implement trading decisions in different market scenarios and structures. Addressing these topics shines a bright light on how a real-world financial market operates, and the simulation provides students with an experiential learning opportunity that is informative and fun.
Light Absorption in Sea Water
Takes a fresh, holistic approach to the problems of light absorption and absorbers in seawaters, discussing the fundamentals of light absorption at various depths in seawaters of different trophicity by absorbers of diverse origin. The authors have drawn their information from a substantial body of contemporary research results published in the subject literature (over 700 references) as well as their own work during the last 30 years. No other book presently available examines the issues of light absorption and absorbers in seawaters in such a manner. The physical and chemical properties, as well as the optical constants, of organic and inorganic suspended particulate matter (SPM), are discussed in the context of their relationship to the light absorption properties of SPM. Special emphasis is placed on the role of the phytoplankton and the pigments it contains which are particularly strong and important absorbers of visible light in the sea.
Lifelong Learning : Interpretations of an Education Policy in Europe
In Europe, the idea of Lifelong Learning has developed from an education policy to the most important pedagogic paradigm. The concept was created as an answer to the international education crisis, diagnozed by Philip H. Coombs in 1967. Since the European Year of Lifelong Learning in 1996, it has been regarded as an alternative to deal with the rapid social, political and economic changes of the modern world. Andrea Óhidy shows the genesis of the concept and its development towards a pedagogic paradigm. She investigates the relations between the concept of Lifelong Learning and school education and points out the most important links between Lifelong Learning and adult education.
Legitimacy In European Nature Conservation Policy : Case Studies In Multilevel Governance
Focuses on the issue of legitimacy in the context of European nature conservation policy. It provides insights in the way in which democratic legitimacy is being ‘produced’ at different levels of governance. Building forth upon recent developments in democracy theory that have identified multiple forms of legitimacy, the volume observes a EU-wide shift from output legitimacy to input and throughput legitimacy. Top down policy making is increasingly meeting
Lasers in the Conservation of Artworks ; LACONA V Proceedings, Osnabrück, Germany, Sept. 15-18, 2003
Since 1995, when Costas Fotakis first brought together restorers and scientists to discuss the potential of lasers in art conservation, the field has grown enormously in importance, and today restorers and laser scientists work together to develop new applications. This book presents the more than six dozen research papers prepared for LACONA V (Lasers in Art Conservation), held in Osnabrueck/Germany in September 2003. The fifth congress once again gathers restorers, art historians, museum staff, laser scientists and laser manufacturers. The topics include, among others: laser cleaning of artworks (case studies and side effects), removal of former conservation layers, fundamentals of laser-artwork interaction, online monitoring and process control, laser diagnostics, spectroscopy for monitoring and identification, networks and co-operation projects.
LASER 2004; Proceedings of the 6th International Workshop on Application of Lasers in Atomic Nuclei Research (LASER 2004) held in Poznan, Poland, 24-27 May, 2004
6th International Workshop on Application of Lasers in Atomic Nuclei Research, LASER 2004, held in Poznan, Poland, 24-27 May, 2004 Researchers and graduate students interested in the Mössbauer Effect and its applications will find this volume indispensable. The volume presents the most recent developments in the methodology of Mössbauer spectroscopy.
Large-Scale Scientific Computing ; 6th International Conference, LSSC 2007, Sozopol, Bulgaria, June 5-9, 2007. Revised Papers
The 6th International Conference on Large-Scale Scienti?c Computations (LSSC 2007) was held in Sozopol, Bulgaria, June 5–9, 2007. The conference was organized by the Institute for Parallel Processing at the Bulgarian Academy of Sciences in cooperation with SIAM (Society for Industrial and Applied Ma- ematics). Partial support was also provided from project BIS-21++ funded by the European Commission in FP6 INCO via grant 016639/2005. The conference was devoted to the 60th anniversary of Richard E. Professor Ewing is internati- ally well known with his contributions in applied mathematics, mathematical modeling, and large-scale scientific computations.
Large-Scale Scientific Computing ; 5th International Conference, LSSC 2005, Sozopol, Bulgaria, June 6-10, 2005, Revised Papers
The 5th International Conference on Large-Scale Scientific Computations (LSSC 2005) was held in Sozopol, Bulgaria, June 6–10, 2003. The conference was organized and sponsored by the Institute for Parallel Processing at the Bulgarian Academy of Sciences. Partial support was also provided from project BIS-21++ funded by the European Commission in FP6 INCO via grant 016639/2005. More than 120 participants from all over the world attended the conference representing some of the strongest research groups in the field of advanced largescale scientific computing. This volume contains 80 papers submitted by authors from over 20 countries. The 6th International Conference, LSSC 2007, will be organized in June 2007
Landslides from Massive Rock Slope Failure
Amongst the thematic topics discussed are global frequency, impacts on society, analysis of initial rock slope failure, monitoring of rock slope movement, analysis and modeling of post-failure behaviour, volcanic landslides, and influences of massive rock slope failure on the geomorphological evolution of mountain regions. Regional contributions include reports on rockslides and rock avalanches in Norway, western Canada, the Andes of Argentina, the Karakoram Himalaya, the European Alps, the Appennines, and the mountains of Central Asia.
Landscapes Under Pressure : Theory and Practice of Cultural Heritage Research and Preservation
This book investigates the newly emerging scope of interests and project agendas to investigate and preserve cultural landscapes. It presents the historic, archaeological, ethnographic, and environmental traditions of cultural landscape study and the attempts to reconstruct and analyze the complex processes of cultural changes through prehistoric and historic times.The "guiding light" of the book is that the fullest understanding of a cultural landscape will materialize through interdisciplinary cooperation, which should involve an ecological approach with historical ecology as the guiding tool, applied archaeology, and environmental planning.
La genetica nell’infertilità maschile = Genetics in male infertility
The notable recent cognitive advances in the field of cytogenetics and molecular genetics have made it possible to identify chromosomal anomalies and gene mutations responsible for numerous male infertility, which were completely ignored until recently. The fact is not without relevance, if the principle is valid that the recognition of the causes of a disease is also the first and necessary approach towards its correct therapy. With this publication, the authors wanted to offer specialists working in the field of assisted reproduction an update on this complex subject, dealing with both genetic causes in male infertility and infertility in genetic diseases.
Knowledge Enterprise : Intelligent Strategies in Product Design, Manufacturing, and Management ; Proceedings of PROLAMAT 2006, IFIP TC5, International Conference, June 15-17 2006, Shanghai, China
Contains the edited version of the technical presentations of PROLMAT 2006, the IFIP TC5 international conference held on June 15-17, 2006 at the Shanghai University in China. The main theme of this conference is Knowledge Enterprise – Intelligent Strategies in Product Design, Manufacturing and Management. These proceedings focus on the issue of how to translate data and information into knowledge in manufacturing enterprises.
