الصفحة 9
الصفحة 9
Modulation of host gene expression and innate immunity by viruses
This book is reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases.
Modern Techniques for Characterizing Magnetic Materials
The book includes, but is not limited to the following areas: Magnetic neutron scattering with 3-axis spectrometer * Small-angle neutrons scattering * Polarized neutron magnetic reflectometry * Resonant soft x-ray magneto-optic scattering * Magnetic hard x-ray scattering * Spin resolved photoemission spectroscopy * Lorentz microscopy and electron holography * Scanning electron microscopy with polarization analysis * Spin polarized low energy electron microscopy * Spin-polarized scanning tunneling microscopy * Magnetic force microscopy * Near-field scanning optical microscopy * Time-resolved scanning Kerr microscopy * Brillouin light scattering spectroscopy
Modern Optical Spectroscopy : With Exercises and Examples from Biophysics and Biochemistry
This textbook offers clear explanations of the theory of optical spectroscopic phenomena and shows how these ideas are used in modern molecular and cellular biophysics and biochemistry. The topics covered include electronic and vibrational absorption, fluorescence, resonance energy transfer, exciton interactions, circular dichroism, coherence and dephasing, ultrafast pump-probe and photon-echo spectroscopy, single-molecule and fluorescence-correlation spectroscopy, Raman scattering, and multiphoton absorption.
Modern Ferrite Technology
odern Ferrite Technology ; 2nd ed. offers the readers an expert overview of the latest ferrite advances as well as their applications in electronic components. This volume develops the interplay among material properties, component specification and device requirements using ferrites. Throughout, emphasis is placed on practical technological concerns as opposed to mathematical and physical aspects of the subject. The book traces the origin of the magnetic effect in ferrites from the level of the simplest particle and then increases the scope to include larger hierarchies. From the desired magnetic properties, the author deduces the physical and chemical material parameters, taking into consideration major chemistry, impurity levels, ceramic microstructures and grain boundary effects. He then discusses the processing conditions and associated conditions required for implementation. In addition to conventional ceramic techniques, he describes non-conventional methods such as co-precipitation, co-spray roasting and single crystal growth.
Modern Differential Geometry in Gauge Theories : Maxwell Fields ; Vol. I
Differential geometry, in the classical sense, is developed through the theory of smooth manifolds. Modern differential geometry from the author’s perspective is used in this work to describe physical theories of a geometric character without using any notion of calculus (smoothness). Instead, an axiomatic treatment of differential geometry is presented via sheaf theory (geometry) and sheaf cohomology (analysis). Using vector sheaves, in place of bundles, based on arbitrary topological spaces, this unique approach in general furthers new perspectives and calculations that generate unexpected potential applications .Volume 1, the focus is on Maxwell fields. All the basic concepts of this mathematical approach are formulated and used thereafter to describe elementary particles, electromagnetism, and geometric prequantization. Maxwell fields are fully examined and classified in the language of sheaf theory and sheaf cohomology.
Modern Developments in X-Ray and Neutron Optics
This volume describes modern developments in reflective, refractive and diffractive optics for short wavelength radiation as well as recent theoretical approaches to modelling and ray-tracing the X-ray and neutron optical systems. It is based on the joint research activities of specialists in X-ray and neutron optics from 11 countries, working together under the framework of the European Programme for Cooperation in Science and Technology (COST, Action P7) in the period 2002--2006. The chapters are written by leading specialists from European laboratories, universities and large facilities. In addition to new ideas and concepts, the contents provide a large amount of practical information about recently implemented devices and methods.
Modern Biogeochemistry : Environmental Risk Assessment
At present, quantitative ecological risk assessment is widely used in different contexts, however very often without an understanding of the natural mechanisms that drive the processes of environmental and human risk. Its application is often accompanied by high uncertainty about risk values. On the other hand, the sustainability of modern technoecosystems is known because of their natural biogeochemical cycling that has been transformed to various extents by anthropogenic studies. Accordingly our understanding of the principal mechanisms that drive the biogeochemical food webs allows us to present a quantitative ecological risk assessment and to propose technological solutions for management of various ERA enterprises. It also enables us to devise a powerful mechanism for ecological insurance, to assign responsibilities and protect rights while managing the control of damage from natural and anthropogenic accidents and catastrophes.
Modern avenues in metal-nucleic acid chemistry
Provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues. More recently, also as a consequence of the advent of supramolecular chemistry, advancements in nanochemistry, and new bio-analytical methods, novel aspects of this field have emerged. MILS-25 gives a state-of-the-art account on the present state of research in this field, addressing, among others, porous materials, non-covalent interactions, stimuli-responsive bioconjugates, DNA-templated metal arrays and nanoclusters, genotyping, guanine quadruplexes, and riboswitches.
Modern Aspects of Spin Physics
The volume investigates central aspects of modern spin physics in the form of extensive lectures on semiconductor spintronics, the spin-pairing mechanism in high- temperature semiconductors, spin in quantum field theory and the nucleon spin.
Modern Anesthetics
Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient is aware but unable to communicate pain because of neuromuscular blockade. in this book the very mechanism of anesthetic action at the biophase” was discussed within the theoretical framework of the “u- tary theory of narcosis”.
Modelling, Analysis and Optimization of Biosystems
Mathematical models in biology and medicine cannot be based on natural laws as it is the case with physics and chemistry. This is due to the fact that biological and medical processes are concerned with living organisms. Mathematical models, however, can be used as a language by which certain aspects of biological or medical processes can be expressed. In general, several mathematical models can be designed in order to describe a biological or medical process and there is no unique criterion which model gives the best description. This book presents several of these models and shows applications of them to different biological and medical problems. The book shows that operations research expertise is necessary in respect to modeling, analysis and optimization of biosystems.
Modelling Environmental Dynamics : Advances in Geomatic Solutions
Modelling environmental dynamics is critical to understanding and predicting the evolution of the environment in response to the large number of influences including urbanisation, climate change and deforestation. Simulation and modelling provide support for decision making in environmental management.
Modelling Critical and Catastrophic Phenomena in Geoscience : A Statistical Physics Approach
This book presents a broad survey of models for critical and catastrophic phenomena in the geosciences, with strong emphasis on earthquakes. It assumes the perspective of statistical physics, which provides the theoretical frame for dealing with complex systems in general. This volume addresses graduate students wishing to specialize in the field and researchers working or interested in the field having a background in the physics, geosciences or applied mathematics.
Modelling and Analysis of Hybrid Supervisory Systems : A Petri Net Approach
Modelling and Analysis of Hybrid Supervisory Systems introduces a modelling formalism that merges Petri nets, differential equation systems and object-oriented methods; a formalism that is adequate for modelling complex and large-scale systems. To guide the designer and conduct hybrid modelling, the book describes a method that starts from the requirements of a supervisory system and results in a proposal for such a system. The method is mainly based on Unified Modelling Language diagrams, well-known tools in both academia and industry. In order to ensure that the supervisory system will behave as expected under any operational circumstances, a validation procedure that allows verification of the formal properties of the hybrid model is presented.
Modeling of Soft Matter
Soft matter plays a role in a wide variety of important processes and application. For example, gel swelling and dynamics are an essential part of many biological and individual processes, such as motility mechanisms in bacteria and the transport and absorption of drugs. Ferroelectrics, liquid crystals, and elastomers are being used to design ever faster switching devices. Experimental studies, such as scattering, optical and electron microscopy, have provided a great deal of detailed information on structures. But the integration of mathematical modeling and analysis with experimental approaches promises to greatly increase our understanding of structure-property relationships and constitutive equations. The workshop on Modeling of Soft Matter has taken such an integrated approach.
Model Based Learning and Instruction in Science
This book describes new, model based teaching methods for science instruction. It presents research that describes these new methods in a very diverse group of settings: middle school biology, high school physics, and college chemistry classrooms. Mental models in these areas such as understanding the structure of the lungs or cells, molecular structures and reaction mechanisms in chemistry, or causes of current flow in electricity are notoriously difficult for many students to learn. Yet these lie at the core of conceptual understanding in these areas. The studies focus on a variety of teaching strategies such as discrepant questioning, analogies, animations, model competition, and hands on activities.
Mobile Professional Voluntarism and International Development : Killing Me Softly?
This book explores the impact that professional volunteers have on the low resource countries they choose to spend time in. Whilst individual volunteering may be of immediate benefit to individual patients, this intervention may have detrimental effects on local health systems; distorting labour markets, accentuating dependencies and creating opportunities for corruption. Improved volunteer deployment may avoid these risks and present opportunities for sustainable systems change. The empirical research presented in this book stems from a specific volunteering intervention funded by the Tropical Health Education Trust and focused on improving maternal and newborn health in Uganda.
Mobile and Wireless Communications Networks ; IFIP TC6 / WG6.8 Conference on Mobile and Wireless Communication Networks (MWCN 2004) October 25-27, 2004 Paris, France
Mobile Ad hoc NETworks (MANETs) has attracted great research interest in recent years. A Mobile Ad Hoc Network is a self-organizing multi-hop wireless network where all hosts (often called nodes) participate in the routing and data forwarding process. The dependence on nodes to relay data packets for others makes mobile ad hoc networks extremely susceptible to various malicious and selfish behaviors. This point is largely overlooked during the early stage of MANET research. Many works simply assume nodes are inherently cooperative and benign. However, experiences from the wired world manifest that the reverse is usually true; and many works [3] [10] [9] [8] [12] [19] have pointed out that the impact of malicious and selfish users must be carefully investigated. The goal of this research is to address the cooperation problem and related security issues in wireless ad hoc networks. As a rule of thumb, it is more desirable to include security mechanisms in the design phase rather than continually patching the system for security breaches. As pointed out in [2] [1], there can be both selfish and malicious nodes in a mobile ad hoc network. Selfish nodes are most concerned about their energy consumption and intentionally drop packets to save power. The purpose of malicious nodes, on the other hand, is to attack the network using various intrusive techniques. In general, nodes in an ad hoc network can exhibit Byzantine behaviors.
Mnemonic Solidarity : Global Interventions
This book provides a concise introduction to a critical development in memory studies. A global memory formation has emerged since the 1990s, in which memories of traumatic histories in different parts of the world, often articulated in the terms established by Holocaust memory, have become entangled, reconciled, contested, conflicted and negotiated across borders
Mixed Finite Elements, Compatibility Conditions, and Applications : Lectures given at the C.I.M.E. Summer School held in Cetraro, Italy June 26–July 1, 2006
Since the early 70's, mixed finite elements have been the object of a wide and deep study by the mathematical and engineering communities. The fundamental role of this method for many application fields has been worldwide recognized and its use has been introduced in several commercial codes. An important feature of mixed finite elements is the interplay between theory and application. Discretization spaces for mixed schemes require suitable compatibilities, so that simple minded approximations generally do not work and the design of appropriate stabilizations gives rise to challenging mathematical problems.
