الصفحة 83
الصفحة 83
Cardiac reconstructions with allograft tissues
Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition ("Cardiac Reconstructions with Allograft Valves") in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table.
Cardiac gene therapy : Methods and protocols
Discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Carbonate Reservoir Characterization : An Integrated Approach
One principal need in petroleum recovery from carbonate reservoirs is the description of the three-dimensional distribution of petrophysical properties in order to improve performance predictions by means of fluid-flow computer simulations. The book focuses on a rock based approach for the integration of geological, petrophysical, and geostatistical methods to construct a reservoir model suitable to input into flow simulation programs. This second edition includes a new chapter on model construction and new examples of limestone, dolostone, and touching-vug reservoir models as well as improved chapters on basic petrophysical properties, rock-fabric/petrophysical relationships, calibration of wireline logs, and sequence stratigraphy.
Carbon Inventory Methods Handbook for Greenhouse Gas Inventory, Carbon Mitigation and Roundwood Production Projects
Carbon Inventory Methods Handbook provides detailed step-by-step information on sampling procedures, field and laboratory measurements, application of remote sensing and GIS techniques, modeling, and calculation procedures along with sources of data for carbon inventory. The unique feature of this handbook is that it provides practical guidance on carbon inventory methods for four kinds of projects, namely, 1) development, implementation and monitoring of carbon mitigation in forest, agriculture and grassland sectors, 2) national greenhouse gas inventory in agriculture, forest, and other land-use categories, 3) forest, grassland and agroforestry development and 4) commercial and community forestry roundwood production.
Carbohydrate-protein interactions : Methods and protocols
Provides new and updated tools for studying protein-carbohydrate interactions ranging from traditional biochemical methods to state-of-the-art techniques. This book focuses on four different research themes detailing methods for screening and quantifying CAZyme activity, investigating the interactions between proteins, carbohydrate ligands, methods for the visualization of carbohydrates, protein-carbohydrate complexes, structural and “omic” approaches for studying systems of CAZymes.
Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine
Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.
Cancer immunotherapy : Methods and protocols
Details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cancer grading manual
Cancer Grading Manual addresses all histopathologic aspects of tumor pathology essential for grading of tumors. It discusses the history and basic tenets of tumor grading; principles of microscopic grading of tumors; ancillary methods currently used to improve tumor grading; and new techniques used in evaluating tumors and formulating prognosis. It is designed to be a practice-oriented, concise and well-illustrated resource for diagnostic surgical pathologists and pathology residents.
Cancer Gene Therapy
the authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation
Cancer et traitement: Domicile ou hôpital : Le choix du patient = Cancer and treatment : Home or hospital : The patient's choice
This book takes stock of the needs, expectations and challenges of caring for a cancer patient at home or in hospital. Indeed, if the number of cancer cases is increasing in Western countries, their management is evolving. The emphasis today is on a more humane announcement of the disease, less aggressive treatments and a better quality of life. Better informed patients often wish to be treated at home. As the survival time lengthens, hospital stays are reduced and chosen. Home care teams will soon be relying on the hospital more easily, thanks to specific communication methods and care networks. Here, all the stakeholders involved in the psycho-oncological approach to the patient discuss the choice of place and means of treatment for patients: from the general practitioner to the psychologist, from the oncologist to the mobile palliative care unit.
Cancer drug safety and public health policy : A changing landscape
Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
Cancer drug resistance : methods and protocols
Discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying quiescent blood-flow circulating cells; and single-cell characterization methods, such as mass cytometry.
Cancer Chemoprevention ; Vol.2 : Strategies for Cancer Chemoprevention
In Cancer Chemoprevention, Volume 2: Strategies for Cancer Chemoprevention, leading chemopreventives investigators comprehensively describe the exciting methodologies that are accelerating progress in the chemoprevention field and review the state of clinical development of preventive agents in the major human cancer target organs. The authors provide sound guidelines for cancer chemopreventive drug development, detailing general strategies and methods for drug discovery, preclinical efficacy, characterization of precancers, safety evaluation of clinical cohorts, and clinical trial design.
Cancer cell biology : methods and protocols
Provides detailed methods on the mechanisms of underlying cancer cell biology. Chapters guide readers through techniques for culturing cancer cell lines, xenografts, cryopreservation of tumor cells, analyzing the co-culture of breast cancer cells, protein secretion by ELISA, flow cytometry-based, multi-parametric immunofluorescence analysis, protein expression by western blot, analysis of surface protein levels, protein recycling by biotinylation assay, and proteomics analysis by liquid chromatography-mass spectrometry.
Cancer and War
Armed conflict, especially the most intense types, indirectly impacts civilian mortality. The estimates suggest that almost 30 million civilian deaths were indirectly attributable to armed conflict globally between 1990 and 2017, two thirds of which were due to communicable, maternal, neonatal, and nutritional diseases. Broader and more robust measures of civilian impacts at subnational and national levels are needed to inform policy and advocacy to prevent war and protect civilians. This could include greater use of linkage studies that incorporate data from routine health and demographic sources, exposure to conflict-specific environmental risks, and quantitative epidemiological methods such as national and subnational victimisation surveys.
Canadian Semantic Web
This book covers a variety of well known topics of interest to practitioners in industry and research scientists. The range of topics includes languages, tools and methodologies for the semantic Web, semantic Web-based ontology management and engineering, semantic Web services, practical applications of the semantic Web techniques, artificial intelligence methods and tools for the semantic Web, software agents on the semantic Web, visualization and modeling of the semantic Web. The goal of this book is to provide a state-of-the-art review of the research as well as to introduce topics of interest to experts.
Calibration Techniques in Nyquist A/D Converters
It is shown that in order to achieve high speed and high accuracy at high power efficiency, calibration is required. Calibration reduces the overall power consumption by using the available digital processing capability to relax the demands on critical power hungry analog components. Several calibration techniques are analyzed. The calibration techniques presented in this book are applicable to other analog-to-digital systems, such as those applied in integrated receivers. Further refinements will allow using analog components with less accuracy, which will then be compensated by digital signal processing. The presented methods allow implementing this without introducing a speed or power penalty.
Calculus of variations and nonlinear partial differential equations : With a historical overview by Elvira Mascolo : Lectures given at the C.I.M.E. Summer School held in Cetraro, Italy, June 27 - July 2, 2005
This volume provides the texts of lectures given by L. Ambrosio, L. Caffarelli, M. Crandall, L.C. Evans, N. Fusco at the Summer course held in Cetraro (Italy) in 2005. These are introductory reports on current research by world leaders in the fields of calculus of variations and partial differential equations. The topics discussed are transport equations for nonsmooth vector fields, homogenization, viscosity methods for the infinite Laplacian, weak KAM theory and geometrical aspects of symmetrization. A historical overview of all CIME courses on the calculus of variations and partial differential equations is contributed by Elvira Mascolo.
Cálculo científico con MATLAB y Octave = Scientific computing with MATLAB and Octave
This textbook is an introduction to Scientific Calculus, illustrating various numerical methods for the computer solution of certain classes of mathematical problems. The authors show how to compute the zeros or integrals of continuous functions, solve linear systems, approximate functions by polynomials, and construct precise approximations for the solution of differential equations. To make the presentation concrete and attractive, the MATLAB programming environment has been adopted as a faithful companion.
Cálculo científico com MATLAB e Octave = Scientific calculus with MATLAB and Octave
Its objective is to present various numerical methods for solving certain mathematical problems on the computer that cannot be treated in a simpler way. Classical issues such as the computation of zeros or integrals of continuous functions, the solving of linear systems, the approximation of functions by polynomials and the construction of precise approximations for solutions of differential equations are addressed. All algorithms are presented in the programming languages MATLAB and Octave, whose main commands and instructions are introduced gradually, aiming in particular at their compatibility in both languages.
