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Köhlers Invention
This scientific biography commemorates the 10th anniversary of Köhler's untimely death. It describes his scientific and personal biography, based on 10 years of close personal and professional relationship between Eichmann and Köhler, as well as interviews with many colleagues and friends, including his "Doktorvater" and mentor Fritz Melchers. Köhler's scientific achievements are explained in a way to make them understandable for the general public and discussed in the historical context of the immunological research at the time.
Kindling 6
A broad array of themes concerned with research on epilepsy and kindling is covered in the book: Pathogenesis of kindling, including developmental patterns; electrophysiology; anatomy, morphology, and neural circuitry; genes, species, and strains; synaptic pharmacology and neurochemistry ; Behavioral consequences of kindling ; Drugs and interventions against kindling ; Clinical relevance of kindling for our understanding of epilepsy in patients
Killer Lymphocytes
This extensively documented, comprehensive survey of cell-mediated cytotoxicity (CMC) traces the history of killer lymphocytes from 1960 to the present, providing a definitive resource for specialists and non-specialists alike.
Keyhole Approaches in Neurosurgery : Vol. I Concept and surgical technique
Offers a detailed systematic overview of the different approaches for minimally invasive craniotomies. After a description of the historical development of the particular craniotomy, each chapter illustrates the anatomical construction of the target region and the surgical approach itself with artistic illustrations and photographs of human cadaver dissections.
Key Clinical Trials in Erectile Dysfunction
Represents a critical appraisal of the major clinical trials that have had a significant impact on clinical research and practice during the last decade. Each trial follows a strict format, starting with reference to the original source of publication, details on the key investigators and their methods of research. The strengths and weaknesses of each trial are discussed as well as their influence on clinical practice. Articles are complemented by a diagrammatic summary of the trial design and the key findings.
Kaposi Sarcoma Herpesvirus : New Perspectives
Since the identificationof two sequences fromKSHV,wehave learnedmuch about this pathogen as reflected in this book. As it turned out, KSHV itself encodes for a number of cytokines, and induces cellular cytokine secretion, contributing to tumour growth. Moreover, KSHV vFLIP targets the IKKNFκB axis to encourage the inflammatory microenvironment observed by Gallo and his colleagues. KSHV continues to elucidate both mechanisms of viral oncogenesis, and cellular and immune pathways involved in non-viral driven neoplasia.
Java for Bioinformatics and Biomedical Applications
Illustrates how individual bioinformatics applications (such as BLAST and Genscan) can be stitched together into a pipeline so that users can direct the output of one tool (for example, gene predictions using Genscan) to perform further analysis (say, homology searching using BLAST).
Japan Nutrition
This auto-translation book demonstrates a time series of nutrition improvement in Japan since the introduction of nutrition sciences to Japan about 150 years ago. The chapters present the historical event where nutritional deficiency due to food shortage was improved in almost a century, by the introduction of nutrition policy and practices such as the "Nutrition Improvement Law". The book contributed to the construction of a longevity nation by resolving the double burden of malnutrition, which is a mixture of undernutrition and overnutrition and creating a social environment in which sustainable healthy diets can be accessed.
Issues of Decapod Crustacean Biology
This volume presents the proceedings of the eighth Colloquium Crustacea Decapoda Mediterranea, which was held at the Ionian University on Corfu Island, Greece, from 2 to 6 September 2002, and reflects recent advancements in decapod crustacean research. The meeting is the oldest European carcinological event, organized regularly at 3-year intervals since 1972. Although focused on the Mediterranean Sea, worldwide contributions provided a forum for fruitful contact and scientific exchange. The book covers up-to-date issues in decapod crustacean research, including genetics, morphology, reproduction, ecology, behaviour and fisheries, and it is primarily aimed at scientists interested in decapod crustacean research, but other scientists and decision-makers working on marine ecology and fisheries will also find up-to-date information on relevant issues.
Computational and Statistical Approaches to Genomics
Computational and Statistical Approaches to Genomics, 2nd Edition, aims to help researchers deal with current genomic challenges. During the three years after the publication of the first edition of this book, the computational and statistical research in genomics have become increasingly more important and indispensable for understanding cellular behavior under a variety of environmental conditions and for tackling challenging clinical problems. In the first edition, the organizational structure was: data à analysis à synthesis à application. In the second edition, the same structure remains, but the chapters that primarily focused on applications have been deleted.
Complications of Regional Anesthesia
This book is an essential text for all anesthesiologists and nurse anesthetists who seek advice on avoiding some of the most common and, more importantly, preventable complications of regional anesthesia and pain medicine. Chapters cover a variety of neurologic complications and pain management issues. Critically important both to patient care and practice management are the chapters focusing on safety and best practice guidelines and the compendium of outcome studies that compare regional and general anesthesia. The book includes an invaluable chapter addressing the important topic of the medical legal aspects of regional anesthesia.
Complications in Gynaecological Surgery
Focusing on a range of gynecological issues, including urinary tract injury, sterilization and assisted pregnancy, as well as the application of cutting-edge laparoscopy, this book will be of great interest and use to the practicing gynecologist or urologist.
Complexity in landscape ecology
Interactions matter. To understand the distributions of plants and animals in a landscape you need to understand how they interact with each other, and with their environment. The resulting networks of interactions make ecosystems highly complex. Recent research on complexity and artificial life provides many new insights about patterns and processes in landscapes and ecosystems. This book provides the first overview of that work for general readers. It covers such topics as connectivity, criticality, feedback, and networks, as well as their impact on the stability and predictability of ecosystem dynamics. With over 60 years of research experience of both ecology and complexity, the authors are uniquely qualified to provide a new perspective on traditional ecology.
Complex Systems Science in Biomedicine
Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts.
Complex Systems in Biomedicine
Features contributions from several Italian research groups that are working on the field of biomedicine. Each chapter in this book deals with a specific subfield, with the aim of providing an overview of the subject and an account of the research results.
Complex Intracellular Structures in Prokaryotes
The new series "Microbiology Monographs" begins with two volumes on intracellular components in prokaryotes. In this second volume, "Complex Intracellular Structures in Prokaryotes", the components, labeled complex intracellular structures, encompass a multitude of important cellular functions. Continuing and newly initiated research will provide a clearer understanding of the complex intracellular structures known at present and will bring to light surprising new ones as well.
Complex Anorectal Disorders : Investigation and Management
Book has focused on the broad structural investigation of the anorectum and on the focused management of largely “functional” problems. And it has done so in style. For this is a core area of specialist practice;your more general colleagues may think twice before referring you new cases of cancer and in?ammatory bowel disease (both also central areas in colorectal surgery), but they will not hesitate in referring the patients whose inves- gation and management are described here. And they will expect you to know how to deal with them. These are some of the most challenging patients to manage. Rightly have the editors covered the physiological areas,rightly the psychological issues, rightly the medicolegal aspects: here is the making of a specialist—the sword and the shield.
Complementary and Alternative Medicine : Ethics, the Patient, and the Physician
Complementary and Alternative Medicine examines the real-life implications of patient issues and the healthcare system in which care is delivered. Because complementary and alternative medicine (CAM) are not presently considered to be a part of conventional medicine, this book discusses the effect that CAM has on patients, physicians, healthcare, and policymakers. Also included are the implications that CAM has on traditional patient-physician relationships as well as the physician's ethical obligations on this subject.
Complement and Kidney Disease
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Competence Assessment in Dementia
The increasing proportion of demented elderly in populations, debates over patient's rights and autonomy, and the growing body of knowledge on dementia has inspired the European Dementia Consensus Network to regard competence assessment in dementia as an important topic of debate.
