الصفحة 8
الصفحة 8
COVID-19: Diagnosis and Treatment
The global coronavirus disease 2019 (COVID- 19) has presented major challenges for clinical laboratories, from initial diagnosis to patient monitoring and treatment. Initial response to this pandemic involved the development, production, and distribution of diagnostic molecular assays at an unprecedented rate, leading to minimal validation requirements and concerns regarding their diagnostic accuracy in clinical settings. In addition to molecular testing, serological assays to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now becoming available from numerous diagnostic manufacturers. In both cases, the lack of peer-reviewed data and regulatory oversight, combined with general misconceptions regarding their appropriate use, have highlighted the importance of laboratory professionals in robustly validating and evaluating these assays for appropriate clinical use.
Conceptual Modelling in Information Systems Engineering
Conceptual modeling has always been one of the cornerstones for information systems engineering as it describes the general knowledge of the system in the so-called conceptual schema.It contiant data modeling, goal-oriented modeling, agent-oriented modeling, and process-oriented modeling. Overall, the contributions reflect the most important developments and application areas of conceptual modeling in recent years, and they also pinpoint trends in conceptual modeling for the next decade.
Conceptual Modeling of Information Systems
When designing an information system, conceptual modeling is the activity that elicits and describes the general knowledge the system needs to know. This description, called the conceptual schema, is necessary in order to develop an information system.textbook explains in detail the principles of conceptual modeling independently from particular methods and languages and shows how to apply them in real-world projects. It covers all aspects of the engineering process from structural modeling over behavioral modeling to meta-modeling, and completes the presentation with an extensive case study based on the osCommerce system, an online store-management software program freely available under the GNU General Public License. His presentation is based on well-known industry standards like UML and OCL as a particular conceptual modeling language, yet also delivers the basics of the formal logical language background.
Conceptual Modeling for Traditional and Spatio-Temporal Applications : The MADS Approach
This book shows that a conceptual design approach for spatio-temporal databases is both feasible and easy to apprehend. While providing a firm basis through extensive discussion of traditional data modeling concepts, the major focus of the book is on modeling spatial and temporal information. Parent, Spaccapietra and Zimányi provide a detailed and comprehensive description of an approach that fills the gap between application conceptual requirements and system capabilities, covering both data modeling and data manipulation features.
Conceptual Modeling - ER 2007 ; 26th International Conference on Conceptual Modeling, Auckland, New Zealand, November 5-9, 2007, Proceedings
Conceptual modeling is fundamental to the development of complex systems, because it provides the key communication means between systems developers, end-users and customers.Conceptua lmodeling provides languages,methods and tools to understand and represent the application domain;to elicitate,concepalize and formalize system requirements and user needs;to communicate systems designs to all stakeholders; to formally verify and validate system designs on high levels of abstractions; and to minimize ambiguities in system development. Initially, conceptual modeling mainly addressed data-intensive information s- tems and contributed to data modeling and database application engineering. The area of conceptual modeling has now matured to encompass all kinds of application areas such as e-applications (including e-business and e-learning), web-based systems (including the semantic web and ubiquitous systems), life science and geographic applications.
Computer Supported Cooperative Work in Design I
The design of complex artifacts and systems requires the cooperation of multidisciplinary design teams using multiple commercial and non-commercial engineering tools such as CAD tools, modeling, simulation and optimization software, engineering databases, and knowledge-based systems. Individuals or individual groups of multidisciplinary design teams usually work in parallel and separately with various engineering tools, which are located on different sites, often for quite a long time. At any moment, individual members may be working on different versions of a design or viewing the design from various perspectives, at different levels of detail. In order to meet these requirements, it is necessary to have effective and efficient collaborative design environments. These environments should not only automate individual tasks, in the manner of traditional computer-aided engineering tools, but also enable individual members to share information, collaborate and coordinate their activities within the context of a design project. CSCW (computer-supported cooperative work) in design is concerned with the development of such environments.
Computational linguistics and intelligent text processing ; Vol. 3406 ; 6th International Conference, CICLing 2005, Mexico City, Mexico, February 13-19, 2005, Proceedings
This book constitutes the refereed proceedings of the 6th International Conference on Computational Linguistics and Intelligent Text Processing, CICLing 2005, held in Mexico City, Mexico in February 2005. An approach that involves natural language analysis techniques for the treatment of software system functional requirements is described in this book. This approach is used as the basis for a process developed to generate sequence diagrams automatically from the textual specification of use cases. This facility has been integrated in the Requirements Engineering Phase of OO-Method, an automatic production environment of software. For this purpose, a translator that is based on natural language parser is used. The translator provides grammatical information to each use case sentence and it identifies the corresponding interaction. The automatic transformation is conceived and specified following an orientation that is based on models and patterns. The results of the validation of the transformation patterns are presented.
Commercial lending : principles and practice
Supports the Chartered Banker Institute's Commercial Lending module requirements and helps to prepare for assessment Is written by a banking sector expert with cutting-edge industry perspective, ideal to support students of banking at undergraduate and postgraduate level Aids work-based learning and professional development with a highly practical and applied approach, bringing learning to life with activities to carry out in the workplace as well as case studies, further reading recommendations and definitions of key terms throughout Offers additional numeracy support to help readers with practical lending work, such as assessing balance sheets and understanding financial reports and documents Offers thought leadership on commercial lending from an expert author with over 30 years of experience in the sector, endorsed by the Chartered Banker Institute
Column Generation
Column Generation is an insightful overview of the state of the art in integer programming column generation and its many applications. The volume begins with "A Primer in Column Generation" which outlines the theory and ideas necessary to solve large-scale practical problems, illustrated with a variety of examples. Other chapters follow this introduction on "Shortest Path Problems with Resource Constraints," "Vehicle Routing Problem with Time Window," "Branch-and-Price Heuristics," "Cutting Stock Problems," each dealing with methodological aspects of the field. Three chapters deal with transportation applications: "Large-scale Models in the Airline Industry," "Robust Inventory Ship Routing by Column Generation," and "Ship Scheduling with Recurring Visits and Visit Separation Requirements." Production is the focus of another three chapters: "Combining Column Generation and Lagrangian Relaxation," "Dantzig-Wolfe Decomposition for Job Shop Scheduling," and "Applying Column Generation to Machine Scheduling." The final chapter by François Vanderbeck, "Implementing Mixed Integer Column Generation," reviews how to set-up the Dantzig-Wolfe reformulation, adapt standard MIP techniques to the column generation context (branching, preprocessing, primal heuristics), and deal with specific column generation issues (initialization, stabilization, column management strategies).
Collaborative Engineering: Theory and Practice
Collaborative Engineering: Theory and Practice offers insights into the methods and techniques involved in implementing a systematic approach to the integrated, concurrent design of products and related processes, including manufacturing, product service and support. The approach discussed here will help developers consider all elements of the product life cycle from conception through disposal, including quality, cost, schedule, and user requirements.
CMOS single chip fast frequency hopping synthesizers for Wireless multi-gigahertz applications : Design methodology, analysis, and implementation
Describes an efficient design and characterization methodology that has been developed to study loop trade-offs in both open and close loop modelling techniques. This is based on a simulation platform that incorporates both behavioral models and measured/simulated sub-blocks of the chosen frequency synthesizer. The platform predicts accurately the phase noise, spurious and switching performance of the final design. Therefore excellent phase noise and spurious performance can be achieved while meeting all the specified requirements. The design methodology reduces the need for silicon re-spin enabling circuit designers to directly meet cost, performance and schedule milestones. The developed knowledge and techniques have been used in the successful design and implementation of two high speed multi-mode fractional-N frequency synthesizers for the IEEE 801.11a/b/g standards. Both synthesizer designs are described in details.
Cloud Computing Infrastructure for Enabling Future Technology Advancement
Presents the most up-to-date information about cloud computing technologies and applications. This book provides a detailed introduction of the research fields, recent work, and open research questions in the emerging field of cloud computing. Also, the present book will look for potential research areas and technologies that will make it easier to build a global market for cloud computing services that support scientific, industrial, business, and consumer applications. The benefits associated with cloud computing are enormous, and for rapid development, there is a massive requirement of research and development in this field.
Clinical trial registries : A practical guide for sponsors and researchers of medicinal products
A necessary addition to the library of all researchers who plan to publish their results in top-tier, peer-reviewed journals. ICMJE editors and other journal editors require registration of clinical trial information on publicly available Web sites before enrollment of study subjects and some countries and regions also require this information, as well as timely publication of study results. Not only does this book discuss the genesis of these requirements, it also provides practical information for researchers and sponsors on how to establish a workflow for a clinical registry project, how to file to a registry, and how to post results. More than 25 current Web addresses for registries are provided as well as a comprehensive annotated bibliography of papers on the topic of clinical trial registries. This book is a valuable source of information for all sponsors of medicinal products.
Mastering VMware Horizon 8 : An Advanced Guide to Delivering Virtual Desktops and Virtual Apps
Learn all about designing, installing, configuring, and managing VMware Horizon, with a core focus on how to deliver virtual desktops using Horizon. This book allows you to follow the complete process for deploying VMware Horizon and covers the design, deployment, and management of solutions. You will: See the core components of VMware Horizon and their functionality / Design and install a Horizon environment / Deliver the best end-user experience / Manage the deployed solution / Use VMware reference architectures to create real-life scenario examples / Review the minimum requirements for designing a solution
Martens and Fishers (Martes) in human-altered environments : An international perspective
Examines the conditions where humans and martens are compatible and incompatible, and promotes land use practices that allow Martes to be representatively distributed and viable. All Martes have been documented to use forested habitats and 6 species (excluding the stone marten) are generally considered to require complex mid- to late-successional forests throughout much of their geographic ranges. All species in the genus require complex horizontal and vertical structure to provide escape cover protection from predators, habitat for their prey, access to food resources, and protection from the elements. Martens and the fisher have high metabolic rates, have large spatial requirements, have high surface area to volume ratios for animals that often inhabit high latitudes, and often require among the largest home range areas per unit body weight of any group of mammals. Resulting from these unique life history characteristics, this genus is particularly sensitive to human influences on their habitats, including habitat loss, stand-scale simplification of forest structure via some forms of logging, and landscape-scale effects of habitat fragmentation. Given their strong associations with structural complexity in forests, martens and the fisher are often considered as useful barometers of forest health and have been used as ecological indicators, flagship, and umbrella species in different parts of the world. Thus, efforts to successfully conserve and manage martens and fishers are associated with the ecological fates of other forest dependent species and can greatly influence ecosystem integrity within forests that are increasingly shared among wildlife and humans.We have made great strides in our fundamental understanding of how animals with these unique life history traits perceive and utilize habitats, respond to habitat change, and how their populations function and perform under different forms of human management and mismanagement.
Manufacturing Systems and Technologies for the New Frontier ; The 41st CIRP Conference on Manufacturing Systems May 26–28, 2008, Tokyo, Japan
Manufacturing systems and technology stand on a new frontier, facing up to the challenges posed by the ever-evolving requirements of global sustainability. Value-creation is taking its place alongside more traditional production-process priorities. Collected here are over a hundred papers concerned with all manner of new directions in manufacturing systems and given at the 41st CIRP Conference on Manufacturing Systems. The high-quality material presented in this volume includes reports of work from both scientific and engineering standpoints and several invited and keynote papers addressing the current cutting edge and likely future trends in manufacturing systems.
Managing Health and Safety in the Dental Practice : A Practical Guide
Provides clear, straightforward information about the key requirements relating to health and safety in dental practices, with a practical and user-friendly approach to help manage these issues on a day-to-day basis.
Managing Agile Business Technology : The Business and Technology Relationship Model in Practice
Describes in detail how the BTRM, combined with a focus on value creation and value delivery, will enable continuous change, in the context of current, emerging and future technologies. It illustrates the potential for real-time insight and control not previously considered and provides a wide range of information to plan an implementation, understand where AI can be applied, and its importance in the world of self-managing systems.
Magnesium Technology : Metallurgy, Design Data, Applications
Magnesium, with a density of 1.74 g/cm², is the lightest structural metal and magnesium are increasingly chosen for weight-critical applications such as in land-based transport systems. "Magnesium Technology" substantially updates and complements existing reference sources on this key material. It assembles international contributions from seven countries covering a wide range of research programs into new alloys with the requisite property profiles, i.e., the current state of both research and technological applications of magnesium. In particular, the international team of authors covers key topics, such as: casting and wrought alloys; fabrication methods; corrosion and protection; engineering requirements and strategies, with examples from the automobile, aerospace, and consumer-goods industries, and recycling.
Magnesium
Until recently the physiological role of magnesium was essentially ignored. However, with the development of new technologies to measure the intracellular free concentration of magnesium ([Mg2+]i), the biologically important fraction, there has been an explosion of interest in the molecular, biochemical, physiological and pharmacological functions of magnesium. In addition improved methods for assessing magnesium status in the clinic have contributed to the further understanding of magnesium regulation in health and disease...
