Bioactive Molecules and Medicinal Plants
Use of medicinal plants is as old as human civilization and continuous efforts are being made to improve medicinal plants or produce their products in high amounts through various technologies. About 200,000 natural products of plant origin are known and many more are being identifed from higher plants and microorganisms. Some plant-based drugs have been used for centuries and there is no alternative medicine for many drugs, such as cardiac glycosides. However, natural products research was sidelined to pave the way for com- natorial chemistry, which was expected to produce large numbers of synthetic compounds for high-throughput screening (HTS). This line of work has failed to deliver desirable results. Moreover, it is not possible for all pharmaceutical companies and institutions to adopt costly HTS technology. Therefore, medi- nal plants and their bioactive molecules are always in demand and are a central point of research. While planning this book, we endeavored to incorporate - ticles that cover the entire gamut of current medicinal plants research.
Bioactive Marine Natural Products
Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R&D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.
Bioactive Heterocycles V
This volume contains 10 chapters. The contributions are from researchers famous in their respective fields and the chapters contain high quality reviews on topics related to the chemo-biological studies of several different heterocyclic groups. The first chapter from Saracoglu reviews the functionalization of indoles and the pyrroles via Michael additions, as these compounds have potential for their biological activities. In second chapter Men ́endez reviews the chemistry of the welwitindolinones. Topcu and Demirkiran, in the third chapter, describe the chemistry and biological studies of lignans from Taxus species, including their biosynthesis and recent strategies for the synthesis of lignans.
Bioactive Heterocycles IV
This volume contains nine more contributions from expert researchers of the?eld, providing readers with in depth and current research results regarding therespective topics. In the?rst chapter, Flemming et al. review the chemistry, biosynthesis, metabolism and biological activities of tetrahydrocannabinol and its deri- tives. Hansch and Verma contribute to the quantitative structure-activity re- tionship (QSAR) analysis of heterocyclic topoisomerase I and II inhibitors. These inhibitors, knowntoinhibit either enzyme, actasantitumoragentsand are currently used in chemotherapy and in clinicaltrials. In the third chapter, Khan reviews some aspects of molecular modeling studies on biologically active alkaloids.
Bioactive Heterocycles III
Bioactive Heterocycles III provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume contains 8 chapters written by experts in their respective ?elds from all over the world. The chapters summarize years of extensive research in each area, and providein sight in the new themesofnaturalproduct research.Manyofthe contributors illustrate their laboratory experiences. It's obvious that readers will gain exciting and essential information fromthe volume. In the ?rst chapter, Kayser et al. describe the chemistry, biosynthesis and biological activities of artemisinin, one of the most promising antimalarial molecules, and its related natural peroxides.
Bioactive Heterocycles II
As part of the series Topics in Heterocyclic Chemistry, this volume titled Bio- tive Heterocycles II presents comprehensive and up-to-date reviews on selected topics regarding synthetic as well as naturally occurring bioactive heterocycles. The frst chapter, "High Pressure Synthesis of Heterocycles Related to Bio- tive Molecules" by Kiyoshi Matsumoto, presents a unique high-pressure s- thetic methodology in heterocyclic chemistry. Basic principles and fruitful examples for pericyclic reactions, such as Diels-Alder reactions, 1,3-dipolar reactions, and also for ionic reactions, such as S and addition reactions, are N discussed.
Anxiety in health behaviors and physical illness
While the links between physical illness and depression have been well-documented and analyzed, little has been made of the data relating physical illness to anxiety—until now. Anxiety in Health Behavior and Physical Illness explores complex relationships between medical and anxiety pathology on the theoretical, research, and practical fronts. Over forty experts examine reciprocal roles of anxiety and medical illness as causal or exacerbating factors in each other’s onset and development, describe forms of anxiety typical to major disease entities, discuss common health behaviors as they impact anxiety, recast anxiety disorders as chronic illness, and identify patients for whom new forms of treatment may be warranted.
Anxiety and substance use disorders : The vicious cycle of comorbidity
Anxiety and Substance Use Disorders: The Vicious Cycle of Comorbidity addresses this gap with dispatches from the frontlines of research and treatment. Thirty-four international experts offer findings, theories, and intervention strategies for this common form of dual disorder both across types of substances (alcohol, tobacco, street and prescription drugs) and the range of anxiety disorders (PTSD, social phobia, panic disorder, OCD) to give the reader comprehensive knowledge in a practical format. Informed by the reciprocal relationship between the two types of disorders
Anthracycline Chemistry and Biology II : Mode of Action, Clinical Aspects and New Drugs
This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The series is still valid and useful after five or ten years. More information as well as the electronic version of the whole content is available at: springerlink.com.
Anthracycline Chemistry and Biology I : Biological Occurence and Biosynthesis, Synthesis and Chemistry
"This book … covers many different aspects of the origin, chemistry, and biosynthesis of one of the oldest but most important classes of anticancer agents. … In summary, the book is nicely produced, very well edited, and should serve as a valuable source of information … . This book will serve as an inspiration for scientists and students in the areas of chemistry, drug discovery, and biological evaluation. It should be an essential addition to institutional library collections … ."









