Medicinal Chemistry for Practitioners
Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.
Medical Technologies in Neurosurgery
The tremendous progress evolving in medical technologies in recent years increasingly influences our daily neurological practice. Ethical aspects in the application of technologies from differing viewpoints are discussed in detail. Additionally, typical examples for the application of medical technologies in the operating room include image processing, robotic devices, and intraoperative imaging are clearly presented.
Medical Imaging and Informatics ; 2nd International Conference, MIMI 2007, Beijing, China, August 14-16, 2007 Revised Selected Papers
This book constitutes the thoroughly refeered post-conference proceedings of the Second Interational Conference on Medical Imaging and Informatics, MIMI 2007, held in Beijing, China, in August 2007.The 40 revised full papers presented together with 4 keynote talks were carefully reviewed and selected from 110 submissions. The papers are organized in topical sections on medical image segmentation and registration, medical informatics, PET, fMRI, ultrasound and thermal imaging, 3D reconstruction and visualization. The volume is rounded off by 4 papers from 2 workshops on legal, ethical and social issues in medical imaging and informatics, as well as on computer-aided diagnosis (CAD).
Medical Image Computing and Computer-Assisted Intervention - MICCAI 2008 ; 11th International Conference, New York, NY, USA, September 6-10, 2008, Proceedings, Part II
The program committee carefully selected 258 revised papers from numerous submissions for presentation in two volumes, based on rigorous peer reviews. The first volume includes 127 papers related to medical image computing, segmentation, shape and statistics analysis, modeling, motion tracking and compensation, as well as registration. The second volume contains 131 contributions related to robotics and interventions, statistical analysis, segmentation, intervention, modeling, and registration.
Medical Image Computing and Computer-Assisted Intervention - MICCAI 2008 ; 11th International Conference, New York, NY, USA, September 6-10, 2008, Proceedings, Part I
The program committee carefully selected 258 revised papers from numerous submissions for presentation in two volumes, based on rigorous peer reviews. The first volume includes 127 papers related to medical image computing, segmentation, shape and statistics analysis, modeling, motion tracking and compensation, as well as registration. The second volume contains 131 contributions related to robotics and interventions, statistical analysis, segmentation, intervention, modeling, and registration.
Mechanisms of Angiogenesis
Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro- and antiangiogenic strategies have found their way into clinical trials. For instance, for the USA, the NIH website in early 2004 displayed 38 clinical studies involving either pro- or antiangiogenic th- apies. Given the expected overwhelming wealth of clinical data, the question may be asked whether further exploration of biological mechanisms is required or whether results from the bedside are instructive enough to proceed. This question depends also on the progress of pro- and antiangiogenic clinical trials. In the following, I give a short overview about some of the progress that has been made in this field. Since Judah Folkman proposed antiangiogenic tumor therapy thirty years ago, it has become increasingly evident that agents which interfere with blood vessel formation also block tumor progression. Accordingly, antiangiogenic therapy has gained much attention as a potential adjunct to conventional c- cer therapy.
Mechanics of Materials
Provides a precise presentation of subjects illustrated with numerous engineering examples that students both understand and relate to theory and application. The tried and true methodology for presenting material gives students the best opportunity to succeed in this course. From the detailed examples, to the homework problems, instructors and students can be confident the material is clearly explained and accurately represented.
Mechanics of biomaterials : Fundamental principles for implant design
Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues.
Mechanics of Biological Tissue
The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book highlights some important research directions that combine mechanical sciences with exciting new developments in biology. This collection of papers should be of interest to theoretical, computational and experimental researchers and doctoral students in the area of biomechanics and in related areas of engineering, biology and medicine.
Mechanical Wave Vibrations: Analysis and Control
Delivers an expert discussion of the wave analysis approach (as opposed to the modal-based approach) to mechanical vibrations in structures. The book begins with deriving the equations of motion using the Newtonian approach based on various sign conventions before comprehensively covering the wave vibration analysis approach. It concludes by exploring passive and active feedback control of mechanical vibration waves in structures.
Maxillofacial surgery and craniofacial deformity: practices and updates
Collects various aspects of facial and cranial deformities in one single textbook in order to have a systematic way of thinking when approaching these interconnected manifestations. Furthermore, other associated social aspects of health care are integrated to give a wider view of the problem and some important considerations of care.
Mathematics of Surfaces XI ; 11th IMA International Conference, Loughborough, UK, September 5-7, 2005, Proceedings
Constitutes the refereed proceedings of the 11th IMA International Conference on the Mathematics of Surfaces, held in Loughborough, UK in September 2005. Among the topics addressed are Voronoi diagrams, linear systems, curvatures on meshes, approximate parameterization, condition numbers, pythagorean hodographs, and more.
Mathematics of Program Construction ; 8th International Conference, MPC 2006, Kuressaare, Estonia, July 3-5, 2006, Proceedings
This volume contains the proceedings of the 8th International Conference on Mathematics of ProgramConstruction, MPC 2006,held at Kuressaare, Estonia, July 3-5, 2006, colocated with the 11th International Conference on Algebraic Methodology and Software Technology, AMAST 2006, July 5-8, 2006. TheMPCconferencesaimtopromotethedevelopmentofmathematicalpr- ciples and techniques that are demonstrably useful and usable in the process of constructing computer programs. Topics of interest range from algorithmics to support for program construction in programming languages and systems.
Mathematics for enzyme reaction kinetics and Reactor performance ; 2 Volumes set
The second volume begins with an introduction to basic concepts in calculus, i.e. limits, derivatives, integrals and differential equations; limits, along with continuity, are further expanded afterwards, covering uni- and multivariate cases, as well as classical theorems. After recovering the concept of differential and applying it to generate (regular and partial) derivatives, the most important rules of differentiation of functions, in explicit, implicit and parametric form, are retrieved – together with the nuclear theorems supporting simpler manipulation thereof. The book then tackles strategies to optimize uni- and multivariate functions, before addressing integrals in both indefinite and definite forms.
Mathematics Education and Language Diversity : The 21st ICMI Study
This book examines multiple facets of language diversity and mathematics education. It features renowned authors from around the world and explores the learning and teaching of mathematics in contexts that include multilingual classrooms, indigenous education, teacher education, blind and deaf learners, new media and tertiary education. Each chapter draws on research from two or more countries to illustrate important research findings, theoretical developments and practical strategies.
Mathematical Techniques in Finance : An Introduction
In Mathematical Techniques in Finance: An Introduction, distinguished finance professional Amir Sadr delivers an essential and practical guide to the mathematical foundations of various areas of finance, including corporate finance, investments, risk management, and more.
Mathematical Models of Distribution Channels
In Chapters 1 and 2 the authors provide an introduction to the current, analytical literature on distribution channels, and they present an intuitively appealing prologue to the Channel Myths that are developed rigorously in later Chapters. In Chapters 3, 4, and 10 they extend the literature by ascertaining the relationship between the manufacturer-optimal wholesale-price strategy and channel breadth. Specific analyses include multiple, non-competing retailers, multiple states-of-nature, and multiple, competing retailers. In Chapters 5-7 the authors determine the profitability of various wholesale-price strategies; this analysis culminates in Chapters 8 and 9 with the determination of the (very limited) conditions under which channel coordination can be optimal for the manufacturer. In Chapter 11 they prove that existing methods of measuring the effect of a change in the degree of inter-retailer substitutability are totally misleading. They then develop an original, theoretical basis for measuring the impact of a change in the degree of inter-retailer substitutability that yields insightful, intuitively appealing results. In Chapter 12 the authors set forth an agenda for future research based on a meta-model that embraces all existing models in the literature. They also issue an appeal for creation of a "Unifying Theory of Distribution Channels" that will enable researchers to work independently and yet to contribute toward the common goal of deepening the marketing science professions’ understanding of distribution channels.
Islamic Philosophy and Occidental Phenomenology on the Perennial Issue of Microcosm and Macrocosm
this volume are reviving the perennial positioning of the human condition in the play of forces within and without the human being. This theme has run from Plato through the Middle Ages, Renaissance and Modernity, and has been ignored by contemporaries. It now acquires a new pertinence and striking significance due to the scientific discoveries into the "infinitely small" in life, on the one hand, and the prodigious technological discoveries of the "infinitely great" on the other. Both open up undreamt-of prospects for the continuing conquest of cosmic forces.
IQ Calibration Techniques for CMOS Radio Tranceivers
There are a lot of factors that degrade the matching of gains and phases between I/Q signals: the instinct layout mismatch, the random mismatch of the devices, the different temperatures over the I/Q signal paths. IQ Calibration Techniques For CMOS Radio Transceivers describes a fully-analog compensation technique without baseband circuitry to control the calibration process. This book will use an 802.11g transceiver design as an example to give a detailed description on the I/Q gains and phases imbalance auto-calibration mechanism.
IoT-enabled Smart Healthcare Systems, Services and Applications
In IoT-Enabled Smart Healthcare Systems, Services and Applications, an accomplished team of researchers delivers an insightful and comprehensive exploration of the roles played by cutting-edge technologies in modern healthcare delivery. The distinguished editors have included resources from a diverse array of learned experts in the field that combine to create a broad examination of a rapidly developing field.



















