الصفحة 7
الصفحة 7
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Human mitochondrial DNA and the evolution of homo sapiens

Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation. It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.

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Hubble : 15 Years of Discovery

This book forms part of the European Space Agency’s 15th anniversary celebration activities for the 1990 launch of the NASA/ESA Hubble Space Telescope. As an observatory in space, Hubble is one of the most successful scientific projects of all time, both in terms of scientific output and its immediate public appeal.Hubble creates an enormous impact by exploiting a unique scientific niche where no other instruments can compete. It consistently delivers super-sharp images and clean, uncontaminated spectra over the entire near-infrared and ultraviolet regions of the electromagnetic spectrum. This has opened up new scientific territory and resulted in many paradigm-breaking discoveries.

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How to Build a Modern Tontine : Algorithms, Scripts and Tips

This book introduces the modern tontine and its applications in retirement and decumulation. Personal financial management in the later stages of life presents unique challenges, and renowned retirement planning expert Dr. Milevsky proposes the modern tontine as a solution. With the goal of guiding professionals and retirees in more efficient decumulation, the book demonstrates how to build a modern tontine. It is technically oriented, employing a cookbook format, featuring R code, and examining retirement planning through a statistical lens.

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Hormonal Carcinogenesis IV

Uniquely, Hormonal Carcinogenesis IV, integrates salient aspects of hormone-related cancers of interest to epidemiologists, basic researchers, and clinicians. The most recent advances in the major hormone-related cancers are presented by leaders of their specialty. The chapters in this volume deal with the causation, dependence, and resistance of endocrine-related cancers with particular emphasis on the most common neoplasms occuring in men and woman world wide, such as breast, prostate, uterine, and ovarian cancers.

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Homing Endonucleases and Inteins

This book provides detailed summary of the genetics, structure, function, mechanisms of action, evolution and engineering of homing endonucleases and inteins. These two unique protein superfamilies have generated considerable excitement for their fundamental, structural, and functional properties, their evolution as parasitic elements, and their widespread applications as gene targeting agents and as instruments for the generation of modified proteins and novel protein combinations.

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Holocaust Survivors and Immigrants : Late Life Adaptations

Based on a unique research study, this volume examines the later life development of Holocaust survivors from Israel and the U.S. Through systematic interviews, the authors -- noted researchers and clinicians -- collected data about the lives of these survivors and how they compared to peers who did not share this experience. The orientation of the book synthesizes several conceptual approaches â€" gerontological and life span development, stress research, and traumatology, and also reflects the varied disciplines of the authors, spanning psychology, social work, and sociology

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History and physical for the pediatric dental patient: establishing a systematic approach for procedural sedation

Serves as a quick reference for all dentists who perform physical exam before the sedation and treatment of pediatric patients. In the dental care setting, pediatric patients present unique challenges to proper sedation and management of dental pathology. A prior history and physical exam is often absent. Learning how to properly conduct a history and physical exam on Pediatric patients is an essential skill for dentists, and has significant implications for parents, patients, and our healthcare system. This book aims for a comprehensive coverage of the review of systems, improve patient care and identify possible complications in pediatric sedation.

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Hipparcos, the New Reduction of the Raw Data

This book provides overviews of the new reduction as well as on the use of the Hipparcos data in a variety of astrophysical implementations. A range of new results, like cluster distances and luminosity calibrations, is presented. The Hipparcos data provide a unique opportunity for the study of satellite dynamics.

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High-quality outdoor learning : Evidence-based education Outside the classroom for children, teachers and society

Reviews evidence and case studies on the effects of outdoor learning on teachers and learners. It shows how real-world learning outside the classroom contributes to unlocking the full potential of learners, demonstrating its benefits for academic learning, social competencies, personal and emotional development, psychological well-being, and physical activity and health. In addition, the book highlights how outdoor learning nurtures environmental awareness and helps learners to tackle current sustainability challenges. Its focus on high-quality learning makes it a unique contribution to the implementation of SDG 4. Aimed at lecturers at teacher training universities, teachers, professional educators, coaches, and multipliers who train staff of educational NGOs, as well as decision makers on all levels of education systems, this book is of interest to all those who seek a more in-depth understanding of the future of education.

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High-Linearity CMOS RF Front-End Circuits

High-Linearity CMOS RF Front-End Circuits presents some unique techniques to enhance the linearity of both the receiver and transmitter. For example, using harmonic cancellation techniques, the linearity of the receiver front-end can be increased by few tens of dB with only minimal impact on the other circuit parameters. The new parallel class A&B power amplifier can not only increase the transmitter's output power in the linear range, but can also result in significant savings in power consumption. High-Linearity CMOS RF Front-End Circuits can be used as a textbook for graduate courses in RF CMOS design and will also be useful as a reference for the practicing engineer.

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High Resolution Infrared Spectroscopy in Astronomy ; Proceedings of an ESO Workshop Held at Garching, Germany, 18-21 November 2003

Two specialized new instruments for ESO's VLT, VISIR and CRIRES, spawned the idea for this workshop. CRIRES is a dedicated very high resolution infrared spectrograph; VISIR features a high resolution spectroscopic mode. Together, the instruments combine the sensitivity of an 8m-telescope with the now well-established reliability of VLT-facility instruments. High resolution here means that lines in cool stellar atmospheres and HII-regions can be resolved. The astrophysical topics discussed in this rather specialized workshop range from the inner solar system to active galactic nuclei. There are many possibilities for new discoveries with these instruments, but the unique capability, which becomes available through high-resolution infrared spectroscopy, is the observation of molecular rotational-vibrational transitions in many astrophysical environments. Particularly interesting and surprising in this context, many papers on modeling and laboratory spectroscopy at the workshop appear to indicate that astronomical observations are lagging a bit behind in this field. The papers are an interesting mix of reports from existing high resolution facilities, reports on modeling efforts of synthetic spectra and reports on laboratory spectra. In this sense, a fruitful exchange between molecular physics and astronomy was again accomplished and is documented in this volume.

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Heterogeneity in statistical genetics : How to assess, address, and account for mixtures in association studies

Heterogeneity, or mixtures, are ubiquitous in genetics. Even for data as simple as mono-genic diseases, populations are a mixture of affected and unaffected individuals. Still, most statistical genetic association analyses, designed to map genes for diseases and other genetic traits, ignore this phenomenon.In this book, we document methods that incorporate heterogeneity into the design and analysis of genetic and genomic association data. Among the key qualities of our developed statistics is that they include mixture parameters as part of the statistic, a unique component for tests of association. A critical feature of this work is the inclusion of at least one heterogeneity parameter when performing statistical power and sample size calculations for tests of genetic association.

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Hepatitis Delta Virus ; Vol. 307

Since its discovery nearly 30 years ago, hepatitis delta virus (HDV) has continued to surprise and fascinate. At 1,680 nucleotides the HDV genome is the smallest known to infect man. It is unique among animal viruses, the closest known relatives being plant viroids. To compensate for its limited protein coding capacity, HDV relies heavily on host functions and on structural features of its circular RNA genome. HDV infection depends on hepatitis B virus as a helper, and increases the severity of liver disease caused by HBV alone. There is currently neither an effective HDV vaccine nor a generally accepted useful therapy for HDV infection. This volume encompasses recent developments in HDV research, from molecular virology to genetics to experimental investigation of new therapeutic and vaccine candidates.

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Healthy Longevity in China : Demographic, Socioeconomic, and Psychological Dimensions

China is aging at an extraordinary speed and has the largest quantity of elderly persons in the world. Scholars utilize this unprecedented living experience of human being and the unique Chinese Longitudinal Healthy Longevity Survey (CLHLS) datasets with the aim to answer in this volume the following questions critical to the aging population world wide. Is the period of disability compressing or expanding with increasing life expectancy and what factors are associated with these trends in the recent decades? Is it possible to realize morbidity compression with a prolongation of the life span in the future?The first section of the book presents the CLHLS project’s study design, sample distribution, contents of data collected, and assessments of age reporting and data quality. The remaining chapters are grouped into sections dealing with the demographic, social, economic, familial and psychological dimensions of healthy longevity.

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Health technology assessments by the National Institute for Health and Clinical Excellence : A qualitative study

This volume dissects the robustness of the agency’s technology appraisal processes as NICE evaluates innovative methods for diagnosis and intervention. Given the unique features of attention-deficit/hyperactivity disorder (ADHD)—starting with it being diagnosed mainly in children and adolescents, its high comorbidity with other psychiatric conditions, and its considerable economic impact—the disorder is a perfect focal point for discussion.

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Harnessing the Power of the Criminal Corpse

This book is the culmination of many years of research on what happened to the bodies of executed criminals in the past. Focusing on the eighteenth and nineteenth centuries, it looks at the consequences of the 1752 Murder Act. These criminal bodies had a crucial role in the history of medicine, and the history of crime, and great symbolic resonance in literature and popular culture. Starting with a consideration of the criminal corpse in the medieval and early modern periods, chapters go on to review the histories of criminal justice, of medical history and of gibbeting under the Murder Act, and ends with some discussion of the afterlives of the corpse, in literature, folklore and in contemporary medical ethics. Using sophisticated insights from cultural history, archaeology, literature, philosophy and ethics as well as medical and crime history, this book is a uniquely interdisciplinary take on a fascinating historical phenomenon.

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Hardware and software : Verification and testing ; 3rd International Haifa Verification Conference, HVC 2007, Haifa, Israel, October 23-25, 2007. Proceedings

These are the conference proceedings of the 4th Haifa Verifcation Conference, held October 27–30, 2008 in Haifa, Israel. This international conference is a unique venue that brings together leading researchers and practitioners of both formal and dynamic verifcation, for both hardware and software systems. This year’s conference extended the successes of the previous years, with a largejumpinthenumberofsubmitted papers. with many more high-quality papers than we had room to accept. Submissions came from 19 di?erent countries, re?ecting the growing international visibility of the conference. Of the 49 submissions, 43 were regular papers, 2 of which were later withdrawn, and 6 were tool papers. After a rigorous review process.

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Hardware and software : Verification and testing ; 1st International Haifa Verification Conference, Haifa, Israel, November 13-16, 2005, Revised Selected Papers

The First Haifa Verification Conference was held at the IBM Haifa Research Lab and at the Haifa University in Israel from November 13 to16, 2005. The conference incorporated three different workshops that took place separately in previous years. The IBM Verification Workshop is now its sixth year, the IBM Software Testing Workshop is now in its fourth year, and the PADTAD Workshop on testing and debugging multi-threaded and parallel software was held for the third time. The Verification Conference was a three-day, single-track conference followed by a one-day tutorial on the testing and review of multi-threaded code. The conference presented a unique combination of fields that brought together the hardware and software testing communities. Merging the different communities under a single roof gave the conference a distinctive flavor and provided the participants with added benefits. While the applications in these separate fields are different, the techniques used are often very similar. By offering lectures in these disparate but related disciplines, the conference engendered an environment of collaboration and discovery.

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Handbook of urban health : Populations, methods, and practice

As more people worldwide live in cities, increasingly we need to understand how cities and city living affect population health. Does city living negatively affect health? Conversely, can city living enhance population health and well-being? Over forty experts from around the world bring a depth of ideas to the Handbook of Urban Health, making the Handbook a focused resource for a range of health disciplines. A unique professional idea book, research resource, and teaching text, the Handbook of Urban Health challenges readers to consider the role that cities plays in shaping population health and to generate solutions that can make cities healthier places for all those who live there.

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Handbook of Response to Intervention : The Science and Practice of Assessment and Intervention

Education professionals have traditionally relied on a wait-to-fail formula to identify and assist students experiencing academic difficulties. With the reauthorization of the Individuals with Disabilities Education Improvement Act, however, a unique early-identification tool – known as response to intervention (RTI) – now offers professionals the option of implementing a collaborative, problem-solving tool designed to ensure that all students achieve academic success.

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