الصفحة 7
الصفحة 7
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Essentials of pharmaceutical analysis

Provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques.

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Ernst Equation and Riemann Surfaces : Analytical and Numerical Methods

Exact solutions to Einstein`s equations have been useful for the understanding of general relativity in many respects. They have led to physical concepts as black holes and event horizons and helped to visualize interesting features of the theory. In addition they have been used to test the quality of various approximation methods and numerical codes. The most powerful solution generation methods are due to the theory of Integrable Systems. In the case of axisymmetric stationary spacetimes the Einstein equations are equivalent to the completely integrable Ernst equation. In this volume the solutions to the Ernst equation associated to Riemann surfaces are studied in detail and physical and mathematical aspects of this class are discussed both analytically and numerically.

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Ergativity : Emerging Issues

This volume presents a collection of papers on the enticing and complex theme of Ergativity. The papers exemplify theoretical depth applied to a wide range of languages, with the majority of papers based on original fieldwork. Ergativity refers to a grammatical pattern in which the logical subject of intransitive clauses and the logical object of transitive clauses share some grammatical features, and in this respect differ from transitive subjects. The shared features are often case and/or agreement, but a variety of other relevant features have also been isolated in the literature.

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Equitable research partnerships : A global code of conduct to counter ethics dumping

This book offers insights into the development of the ground-breaking Global Code of Conduct for Research in Resource-Poor Settings (GCC) and the San Code of Research Ethics. Using a new, intuitive moral framework predicated on fairness, respect, care and honesty, both codes target ethics dumping – the export of unethical research practices from a high-income setting to a lower- or middle-income setting. The book is a rich resource of information and argument for any research stakeholder who opposes double standards in research. It will be indispensable for applicants to European Union framework programmes, as the GCC is now a mandatory reference document for EU funding.

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Epigenome editing : Methods and protocols

This second volume details new and updated methods covering applications of epigenome editing. Chapters guide readers through general and topical reviews, DNA-binding devices, optimization of the effector domains, readout of epigenome marks, and approaches for delivery at the cellular and organismal level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

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Epigenetics in oncology

Covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years. Individual chapters in Part I (focusing on RNA epigenetics) are devoted to RNA modifications in Cancer Metabolism and Microenvironment, Cancer Stem Cell Biology, Immune Surveillance, Solid Tumors and Tumor Immunity, and Hematopoietic Malignancies, as well as to RNA editing in Cancer. Chapters in Part II and III of the book focus on histone epigenetics and DNA epigenetics, respectively.

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Enzyme Biocatalysis : Principles and Applications

This book was written with the purpose of providing a sound basis for the design of enzymatic reactions based on kinetic principles, but also to give an updated vision of the potentials and limitations of biocatalysis, especially with respect to recent app- cations in processes of organic synthesis. The ?rst ?ve chapters are structured in the form of a textbook, going from the basic principles of enzyme structure and fu- tion to reactor design for homogeneous systems with soluble enzymes and hete- geneous systems with immobilized enzymes. The last chapter of the book is divided into six sections that represent illustrative case studies of biocatalytic processes of industrial relevance or potential, written by experts in the respective ?elds.

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Environmental Security and Public Safety ; Problems and Needs in Conversion Policy and Research after 15 Years of Conversion in Central and Eastern Europe

Although the end of the Cold War has paved the way to a substantial demilitarisation and conversion, the leftovers of this process – such as former military installations, military training areas, and huge quantities of unserviceable ammunition and equipment – still pose a severe threat to the environment of both NATO and Partner countries.The rehabilitation of these areas for civilian uses is extremely costly and is generally in the short and medium term not possible. For this reason, the development of new methods for the estimation avoidance of risks should receive special priority. In the context of this ARW, the reconnaissance and appraisal of conversion areas with respect to costs, returns, and legal considerations were discussed. The decades-long use of some areas led to the heavy loading of contaminates. Every task of conversion has as its goal the elimination of dangers to humans and nature, and the return of areas to civil use, such that these areas can be used realise economic interests of the society.

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Entropy, Search, Complexity

The present volume is a collection of survey papers in the fields of entropy, search and complexity. They summarize the latest developments in their respective areas.More than half of the papers belong to search theory which lies on the borderline of mathematics and computer science, information theory and combinatorics, respectively. Search theory has variegated applications, among others in bioinformatics. Some of these papers also have links to linear statistics and communicational complexity.

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Entropy and Energy : A Universal Competition

Entropy and Energy- a Universal Competition" is a students textbook as well as a scientific monograph. The concepts of entropy and energy embody the effects of random walk in a body and of deterministic strife respectively, and are therefore often in competition. The book gives instructive examples from elementary thermodynamics and physico-chemistry and extrapolates the notion to non-standard thermodynamic subjects like shape memory, dissipation of the earth's atmosphere, and sociology

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Enhancing Smallholder Farmers' Access to Seed of Improved Legume Varieties Through Multi-stakeholder Platforms : Learning from the TLIII project Experiences in sub-Saharan Africa and South Asia

This book shares the experiences of Tropical Legumes III (TLIII) project in facilitating access to seed of improved legume varieties to smallholder farmers through innovation platforms. It highlights practices and guiding principles implemented in eight developing countries of sub-Saharan Africa and South Asia. This book details key processes that respective teams employed to create an innovation space that delivers seed, other inputs, knowledge and financial services to agricultural communities and most importantly, the underserved farmers in remote areas of the drylands

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Emerging States at Crossroads

This volume analyzes the economic, social, and political challenges that emerging states confront today. Notwithstanding the growing importance of the ‘emerging states’ in global affairs and governance, many problems requiring immediate solutions have emerged at home largely as a consequence of the rapid economic development and associated sociopolitical changes. The middle-income trap is a major economic challenge faced by emerging states. This volume regards interest coordination for technological upgrading as crucial to avoid the trap and examines how various emerging states are grappling with this challenge by fostering public-private cooperation, voluntary associations of market players, and/or social networks. Social disparity is another serious problem. This volume argues that the economic, social, and political problems are interwoven in the sense that the emerging states need to build political consensus in order to tackle the economic and social difficulties. Democratic institutions have not always been successful in this respect.

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Emerging Contaminants from Industrial and Municipal Waste : Removal Technologies

This book focuses on innovative treatment technologies for the elimination of emerging contaminants from wastewater and drinking water. The respective treatment processes, such as membrane bioreactors, photocatalysis, ozonation and advanced oxidation are dealt with in detail. The book also discusses sources and occurrence of emerging contaminants in municipal and industrial waste, giving a concise and critical overview of state-of-the-art analytical methods for their identification. Further important aspects covered by the book include the acute and chronic effects and overall impact of emerging contaminants on the environment.

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Emerging Contaminants from Industrial and Municipal Waste : Occurrence, Analysis and Effects

This book focuses on innovative treatment technologies for the elimination of emerging contaminants from wastewater and drinking water. The respective treatment processes, such as membrane bioreactors, photocatalysis, ozonation and advanced oxidation are dealt with in detail. The book also discusses sources and occurrence of emerging contaminants in municipal and industrial waste, giving a concise and critical overview of state-of-the-art analytical methods for their identification. Further important aspects covered by the book include the acute and chronic effects and overall impact of emerging contaminants on the environment.

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Embedded systems design : The ARTIST roadmap for research and development

Embedded systems now include a very large proportion of the advanced products designed in the world, spanning transport (avionics, space, automotive, trains), electrical and electronic appliances (cameras, toys, televisions, home appliances, audio systems, and cellular phones), process control (energy production and distribution, factory automation and optimization), telecommunications (satellites, mobile phones and telecom networks), and security (e-commerce, smart cards), etc. The extensive and increasing use of embedded systems and their integration in everyday products marks a significant evolution in information science and technology. We expect that within a short timeframe embedded systems will be a part of nearly all equipment designed or manufactured in Europe, the USA, and Asia. There is now a strategic shift in emphasis for embedded systems designers: from simply achieving feasibility, to achieving optimality. Optimal design of embedded systems means targeting a given market segment at the lowest cost and delivery time possible. Optimality implies seamless integration with the physical and electronic environment while respecting real-world constraints such as hard deadlines, reliability, availability, robustness, power consumption, and cost. In our view, optimality can only be achieved through the emergence of embedded systems as a discipline in its own right.

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Elements of spatial structures : Analysis and design

Highlights all aspects of the analysis and design of elements related to spatial structures, which have been carefully selected from existing structures. Analysing the design of elements of any full scale structure that contains facilities that have already been constructed makes good economic sense and avoids duplication in respect of research and development, the decision-making process and accurate design criteria for new constructed facilities.

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Electronic Postage Systems : Technology, Security, Economics

This book introduces a taxonomy of electronic postage systems and explains their security risks and countermeasures. The underlying cryptographic mechanisms are introduced and explained, and the industrial-scale electronic postage systems existing worldwide, are sorted out with respect to this taxonomy. The author also discusses privacy and anonymous mail, the state of standardization of electronic postage, and the process of security evaluation and testing of electronic postage systems. This volume including electronic postage designers of postal operators and standardization bodies, software and test engineers, software vendors integrating electronic postage solutions into their applications, security engineers and cryptography experts, and accredited test laboratories evaluating electronic postage systems.

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Elastic Multibody Dynamics : A Direct Ritz Approach

This textbook is an introduction to and exploration of a number of core topics in the field of applied mechanics: On the basis of Lagrange's Principle, a Central Equation of Dynamics is presented which yields a unified view on existing methods. From these, the Projection Equation is selected for the derivation of the motion equations of holonomic and of non-holonomic systems. The method is applied to rigid multibody systems where the rigid body is defined such that, by relaxation of the rigidity constraints, one can directly proceed to elastic bodies. A decomposition into subsystems leads to a minimal representation and to a recursive representation, respectively, of the equations of motion.

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Educational research : The educationalization of social problems

In this book distinguished philosophers and historians of education focus on ‘educationalization’ to expand its meaning through an engagement with educational theory. Topics discussed are the family and the child, the ‘learning society’, citizenship education, widening participation in higher education, progressive education, and schooling movements such as No Child Left Behind. ‘Smeyers’ and Depaepe's book offers great insights into one of the most ambivalent phenomena of today's educational world and especially educational policy. The contributions assembled represent perspectives of some of the most respected scholars in the field.

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Education and Social Justice

The book explores the problematic relationship between education, social justice and the State, against the background of comparative education research. Social justice is an attempt to answer the following question: How can we contribute to the creation of a more equitable, respectful, and just society for everyone? The creation of a more equitable, respectful, and just society for everyone is a dream for all empowering and egalitarian pedagogues. But it will remain a mere hollow rhetoric, or magic words, unless we debate more vigorously social inequality in the global culture. The book critiques the existing status quo of stratified school systems, and the unequal disctribution of cultural capital and value added schooling.

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