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الصفحة 7
الصفحة 7
Cancer vaccination and challenges Vol.2 : delivery strategies for cancer vaccine and immunotherapy in the management of various carcinomas
Covers delivery strategies of cancer vaccines for the management of various forms of carcinoma, examining the prospects of delivering immuno-oncology therapies, focusing specifically on effective drug delivery strategies for the treatment of lung, prostate, and pancreatic carcinomas.
Cancer Survivorship : Today and Tomorrow
A diagnosis of cancer provokes myriad responses in patients, chief among them the question: "how long do I have to live?" Increasingly, the answer to that question is not one of months or years, but decades. While there are now nearly 10 million people in the United States who have recovered or are currently recovering from cancer (increased from three million in 1971), the unique challenges encountered by survivors are often met with uncertainity by even the most seasoned physicians, nurses, and clinical social workers because of a lack of formal guidelines for post-treatment care and follow-up.
Cancer Proteomics : From Bench to Bedside
the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.
Cancer Informatics in the Post Genomic Era : Toward Information-Based Medicine
Medical information science requires analytic tools. This is achieved by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools.Key challenges include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.Addressing important clinical questions in cancer research will benefit from expanding computational biology.
Cancer in the Arab World
Over the past few decades, the Arab world has witnessed a swift evolution in healthcare provision. Nonetheless, Arab countries have considerable variability in economic capabilities, resource allocation, and intellectual talent that inevitably reflect on access to modern cancer care and prevention. This book is authored by experts from the Arab world who provide vital information on cancer statistics and risk factors, available clinical care pathways and infrastructure, and prevention programs in their individual countries. The chapters also address specific challenges in each country and insights into future directions to achieve optimal care with conventional and novel diagnostics and therapies to keep up with the era of precision medicine.
Cancer in adolescents and young adults
The chapters highlight the initial efforts of this Committee in addressing the scope of the problem of adolescent and young adult underrepresentation in clinical trials and offer evidence that such adiscrepancy may partially explain outcome differences.In addition, these chapters present information about biologic differences between specific cancer subtypes most common in younger children and those exhibited by the same cancers in adolescents and young adults, and offer plausible explanations for outcome differences as well as potential treatment strategies.
Cancer immunotherapy : Methods and protocols
Details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cancer grading manual
Cancer Grading Manual addresses all histopathologic aspects of tumor pathology essential for grading of tumors. It discusses the history and basic tenets of tumor grading; principles of microscopic grading of tumors; ancillary methods currently used to improve tumor grading; and new techniques used in evaluating tumors and formulating prognosis. It is designed to be a practice-oriented, concise and well-illustrated resource for diagnostic surgical pathologists and pathology residents.
Cancer et traitement: Domicile ou hôpital : Le choix du patient = Cancer and treatment : Home or hospital : The patient's choice
This book takes stock of the needs, expectations and challenges of caring for a cancer patient at home or in hospital. Indeed, if the number of cancer cases is increasing in Western countries, their management is evolving. The emphasis today is on a more humane announcement of the disease, less aggressive treatments and a better quality of life. Better informed patients often wish to be treated at home. As the survival time lengthens, hospital stays are reduced and chosen. Home care teams will soon be relying on the hospital more easily, thanks to specific communication methods and care networks. Here, all the stakeholders involved in the psycho-oncological approach to the patient discuss the choice of place and means of treatment for patients: from the general practitioner to the psychologist, from the oncologist to the mobile palliative care unit.
Cancer du testicule = Testicular cancer
Testicular cancer has benefited from important therapeutic advances radically transforming its prognosis. Recent protocols have led to the development of treatments that maintain therapeutic efficacy while favoring quality of life and minimizing the sequelae (such as fertility disorders) in these often young men. This book discusses the various technical advances both in the field of diagnosis - with the contribution of modern imaging and anatomopathology - and therapy. The place of chemotherapy as well as that of surgery are largely detailed, thus placing the urologist at the heart of the multidisciplinary team taking care of these patients. Quality of life is also discussed by taking into account the impact of the treatment of these tumors on the fertility of these young patients.
Cancer drug safety and public health policy : A changing landscape
Description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. Opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety.
Cancer Clinical Trials : Proactive Strategies
The ever-changing regulations for clinical trials and the ethical dilemma of treating cancer patients as subjects have made it ever so difficult for the principal investigators to conduct clinical research, especially when they are often ill-informed of the complex nature of the regulations and over-worked. Therefore, cancer clinical trials are at a critical junction. The objective of this book is to bring the issues of cancer clinical trials into focus so that proactive strategies may be developed to make such trials more user-friendly. Ultimately, the cancer patients will be benefited.
CADD and informatics in drug discovery
Updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas / presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, RandD personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (RandD), the academic as well as research sectors. .
Brodmann's : Localisation in the Cerebral Cortex
It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology.
Bringing Pain Relief to Children : Treatment Approaches
In Bringing Pain Relief to Children: Treatment Approaches, a panel of prominent clinician-scientists comprehensively reviews the latest developments in pediatric pain management, with special emphasis on the setting in which pain is detected and managed. The authors explore the cutting-edge of children's pain care in inpatient, outpatient, palliative care, school, and residential settings, and describe alternate approaches, including complementary and alternative medicine, pain management via the internet and information technology, and pain care in developing countries.
Breast MRI : Fundamentals and technical aspects
The text walks the reader through the basics of MRI, making it especially accessible to beginners. From a detailed outline of equipment prerequisites for obtaining high quality breast MRI to instructions on how to optimize image quality, expanded discussions on how to obtain optimized dynamic information.
Breast MRI : Diagnosis and Intervention
This superbly illustrated practical guide is an excellent resource on all aspects of breast MRI for practicing radiologists, oncologists, and surgeons, as well as residents and fellows. Drs. Elizabeth Morris and Laura Liberman, two experts in the field from the Memorial Sloan-Kettering Cancer Center, have collaborated with colleagues from their institution and selected medical centers to share their expertise. Introductory chapters are devoted to diagnosis and cover the basics of performing breast MRI exams, setting up a breast MRI program, and understanding clinical indications. Additional chapters discuss breast interventional procedures including MRI-guided needle localization, MRI-guided biopsy, and percutaneous ablation of breast cancer; MRI of breast implants.
Breast cytopathology
Breast Cytopathology by Syed Ali, MD and Anil Parwani, MD will fulfill the need for an easy-to-use and authoritative synopsis of breast cytopathology. This volume, part of the Essentials in Cytopathology book series, fits into the lab coat pocket and is ideal for portability and quick reference. Each volume in the series is heavily illustrated with a full color art program, while the text follows a user-friendly outline format.
Breast cancer genetics, immunology, and immunotherapy : An interdisciplinary approach
Publishes comprehensive volumes on immune and genetic mechanisms of breast cancer diagnosis and prognosis. The role of molecular genetics, interleukins, chemokine receptor, and tumor-infiltrated lymphocytes-TILS in breast cancer are explained. Targeting myeloid determinants, SiRNA loaded in drug delivery nanosystems, nucleic acid and drug dual agent nanoplatforms, and oncolytic virotherapy are also discussed in the treatment of breast cancer, particularly in multidrug resistant and metastatic breast cancer.
Breast cancer : Nuclear medicine in diagnosis and therapeutic options
This book provides general information on breast cancer management and considers all new methods of diagnosis and therapy. It focuses on nuclear medicine modalities by comparing their results with other diagnostic and therapeutic approaches.
