الصفحة 67
الصفحة 67
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An introduction to generative drug discovery

Describes the state‑of‑the‑art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology. It will provide a foundation for those new to the field as well as those that may already have some experience of its utility. With contributions from scientists in both academia and industry ‘Introduction to Generative Drug Discovery’ may represent one of the earliest if not the first book to focus on this topic.

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An introduction to cable roof structures ; 2nd ed.

Provides structural engineers with a concise introduction to the architectural, structural and technological aspects of cable roofs, and supplies sufficient information for engineers to carry out their own designs. The improved methods for generating wind and earthquake histories have been included as the trend in modern design codes seem increasingly to require that dynamic response of other forms of non-linear structures such as guyed masts is considered at the design stage.

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An introduction to bioanalysis of biopharmaceuticals

Provides a comprehensive review of the fundamental and practical aspects of bioanalytical support and the integral role it plays in the development of safe and efficacious biopharmaceutical drugs with speed and cost-effectiveness. Focuses on a broad range of conventional and emerging biopharmaceutical modalities including monoclonal antibody-based therapeutics, gene therapy, cell therapy, peptides and oligonucleotides.

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An Energy Analysis of Household Consumption : Changing Patterns of Direct and Indirect Use in India

The book presents a novel socio-economic approach to analysing the - ergy system and energy consumption in India from a household persp- tive. In doing so, it views households as the ultimate end-consumers and estimates and analyses the direct and indirect energy requirements of household consumption, both at an aggregate national level as well as at a disaggregate household level. In addition, the work incorporates two c- cial aspects often ignored by many energy studies that are characteristic of most developing countries, namely the importance of non-commercial sources of biomass energy in the energy systems of these countries, and the enormous diversity and inequity in the patterns of energy access and use across households with different lifestyles and levels of well being.

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An ecological and societal approach to biological control

Biological control is among the most promising methods for control of pests (including vectors), diseases and weeds. In this book ecological and societal aspects are for the first time treated together. In an ecological approach the aim is to evaluate the significance of certain biological properties like biodiversity and natural habitats. Also, it is important to see biological control from an organic (or ecological) farming point of view. In a societal approach terms like ‘consumer’s attitude’, ‘risk perception’, ‘learning and education’ and ‘value triangle’ are recognised as significant for biological production and human welfare.

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Ambient Intelligence in Everyday Life : Foreword by Emile Aarts

Originating from the Workshop on Ambient Intelligence in Everyday Life held at the Miramar Congress Center, San Sebastian, Spain, in July 2005, this book is devoted to the cognitive aspects of ambient intelligence. The 15 carefully reviewed and revised articles presented are organized in topical sections on human-centric computing, ambient interfaces, and architectures for ambient intelligence.

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Alzheimers disease : Cellular and molecular aspects of Amyloid beta

This book contains a survey of present-day research into the biomedical fundamentals of Alzheimer’s disease (AD). It contains 20 chapters dealing with widely ranging topics, all of which have a bearing upon the understanding and treatment of AD. Starting with a broad survey of the contribution that the various microscopical techniques (light microscopy, electron microscopy, atomic force microscopy)

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Alvar Aalto : Das Gesamtwerk = L'oeuvre complète = The Complete Work ; 3 Vol.s

Aalto's designs encompassed the fields of painting, architecture, sculpture, and furniture, and are some of the most beautiful and original of modern times. His combination of an interest in natural, organic shapes with the modernist mandates of form and light in its purest aspects makes him one of the acknowledged masters of modern architecture, along with Le Corbusier and Frank Lloyd Wright.

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Allergy in Practice

This book reflects the rich personal experience of a German allergist with international training and reputation, who is active in immunology and allergy research and practice for almost 30 years. In this book, not only IgE-mediated allergic reactions are covered but all other kinds of allergies such as atopic eczema, contact dermatitis, drug eruptions, anaphylaxis and food allergies are equally represented as well as psychosomatic aspects and problems of environmental intolerances.

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Allelopathy : A Physiological Process with Ecological Implications

This book provides the reader relevant information about actual knowledge about the process of allelopathy, covering all aspects from the molecular to the ecological level. Special relevance is given to the physiological and ecophysiological aspects of allelopathy. Several ecosystems are studied and methodological considerations are taken into account in several different chapters. The book has been written to be useful both for Ph.D. students and for senior researchers, so the chapters include all necessary information to be read by beginners, but they also include a lot of useful information and discussion for the initiated.

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Aligner systems in invisible orthodontics: basic concepts and clinical management

Describes the processes, techniques and biomechanics involved in providing aligner treatment for different types of malocclusions. It opens with an overview of the material characteristics and the basic concepts of aligner therapy including topics like biocompatibility and intraoral deterioration. The main part of the book is dedicated to the various types of aligners, the methods used in their application and the practical aspects of delivery. It is structured based on the type of malocclusion being managed giving the reader a systematic pattern and a practical way of progressing through the book. The book closes with a discussion of the scientific data available.

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Algorithms in Real Algebraic Geometry

The algorithmic problems of real algebraic geometry such as real root counting, deciding the existence of solutions of systems of polynomial equations and inequalities, finding global maxima or deciding whether two points belong in the same connected component of a semi-algebraic set appear frequently in many areas of science and engineering. In this first-ever graduate textbook on the algorithmic aspects of real algebraic geometry, the main ideas and techniques presented form a coherent and rich body of knowledge, linked to many areas of mathematics and computing.

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Algorithms in Bioinformatics ; Vol. 3692 ; 5th international workshop, WABI 2005, Mallorca, Spain, October 3-6, 2005, Proceedings

this book present the proceedings of the 5th Workshop on Algorithmsin Bioinformatics (WABI 2005) which took place in Spain, 2005. The Workshop on Algorithms in Bioinformatics highlights research workspecifically developed to address algorithmic problems in biosequence analysis. The emphasis is therefore on statistical and probabilistic algorithms that addressimportant problems in the field of molecular and structural biology. the workshop aims to present recent research results, includingsignificant work in progress, and to identify and explore directions of futureresearch.Original research papers (including significant work in progress) or state-of-the-art surveys were solicited on all aspects of algorithms in bioinformatics,including, but not limited to: exact and approximate algorithms for genomics,genetics, sequence analysis, gene and signal recognition, alignment, molecularevolution, phylogenetics, structure determination or prediction, gene expressionand gene networks, proteomics, functional genomics, and drug design.

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Algorithms – ESA 2005 ; 13th Annual European Symposium, Palma de Mallorca, Spain, October 3-6, 2005, Proceedings

This volume contains the 75 contributed papers and the abstracts of the threeinvited lectures presented at the 13th Annual European Symposium on Algo-rithms (ESA 2005), held in Spain, 2005. respectively.Papers were solicited in all areas of algorithmic research, including but notlimited to algorithmic aspects of networks, approximation and on-line algo-rithms, computational biology, computational geometry, computational financeand algorithmic game theory, data structures, database and information re-trieval, external memory algorithms, graph algorithms, graph drawing, machinelearning, mobile computing, pattern matching and data compression, quantumcomputing, and randomized algorithms. The algorithms could be sequential,distributed, or parallel. Submissions were especially encouraged in the area ofmathematical programming and operations research, including combinatorialoptimization, integer programming, polyhedral combinatorics, and semidefiniteprogramming.Each extended abstract was submitted to one of the two tracks.

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Algorithmic Aspects of Wireless Sensor Networks ; 4th International Workshop, ALGOSENSORS 2008, Reykjavik, Iceland, July 2008. Revised Selected Papers

This book constitutes the reviewed proceedings of the Fourth International Workshop on Algorithmic Aspects of Wireless Sensor Networks, ALGOSENSORS 2008, held in Reykjavik, Iceland, Wroclaw, Poland, July 12, 2008.

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Algorithmic Aspects of Wireless Sensor Networks ; 3rd International Workshop, ALGOSENSORS 2007, Wroclaw, Poland, July 14, 2007, Revised Selected Papers

This book contains the proceedings of the Third International Workshop on Algorithmic Aspects of Wireless Sensor Networks. Coverage includes abstract models, complexity-theoretic results, and the design and analysis of algorithms for wireless sensor networks.

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Algorithmic Aspects of Wireless Sensor Networks ; 2nd International Workshop, ALGOSENSORS 2006, Venice, Italy, July 15, 2006, Revised Selected Papers

This volume contains the contributed papers and invited talks presented at the 1stInternational Workshop on Algorithmic Aspect sof Wireless Sensor Networks (ALGOSENSORS 2004), which was held July 16, 2004, in Turku, Finland, - located with the 31st International Colloquium on Automata, Languages, and Programming (ICALP 2004). Wireless ad hoc sensor networks have become a very important research subject due to their potential to provide diverse services in numerous appli- tions. The realization of sensor networks requires intensive technical research and development e?orts, especially in power-aware scalable wireless ad hoc c- munications protocols, due to their unusual application requirements and severe constraints. On the other hand, a solid theoretical background seems necessary for sensor networks to achieve their full potential. It is an algorithmic challenge to achieve e?cient and robust realizations of such large, highly dynamic, complex, n- conventional networking environments

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Algorithmic Aspects of Bioinformatics

Advances in bioinformatics and systems biology require improved computational methods for analyzing data, while progress in molecular biology is in turn influencing the development of computer science methods. This book introduces some key problems in bioinformatics, discusses the models used to formally describe these problems, and analyzes the algorithmic approaches used to solve them. After introducing the basics of molecular biology and algorithmics, Part I explains string algorithms and alignments; Part II details the field of physical mapping and DNA sequencing; and Part III examines the application of algorithmics to the analysis of biological data. Exciting application examples include predicting the spatial structure of proteins, and computing haplotypes from genotype data. This book describes topics in detail and presents formal models in a mathematically precise, yet intuitive manner, with many figures and chapter summaries, detailed derivations, and examples. It is well suited as an introduction into the field of bioinformatics, and will benefit students and lecturers in bioinformatics and algorithmics, while also offering practitioners an update on current research topics.

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Algorithmic Aspects in Information and Management ; Second International Conference, AAIM 2006, Hong Kong, China, June 20-22, 2006, Proceedings

This book constitutes the refereed proceedings of the Second International Conference on Algorithmic Aspects in Information and Management, AAIM 2006, held in Hong Kong, June 2006. The book presents 34 revised full papers together with abstracts of 2 invited talks. The papers cover topics from areas such as online scheduling, game and finance, data structures and algorithms, computational geometry, optimization, graph, and string, and more.

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Algorithmic Aspects in Information and Management ; 4th International Conference, AAIM 2008, Shanghai, China, June 23-25, 2008. Proceedings

This book constitutes the refereed proceedings of the 4th International Conference on Algorithmic Aspects in Information and Management, AAIM 2008, held in Shanghai, China, in June 2008.

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