الصفحة 6
الصفحة 6
Pitch : Neural Coding and Perception
Although pitch has been considered an important area of auditory research since the birth of modern acoustics in the 19th century, some of the most significant developments in our understanding of this phenomenon have occurred comparatively recently. In auditory physiology, researchers are now identifying cells in the brainstem and cortex that may be involved in the derivation of pitch. In auditory psychophysics, dramatic developments over the last several years have changed our understanding of temporal pitch mechanisms, and of the roles of resolved and unresolved harmonics. Computational modeling has provided new insights into the biological algorithms that may underlie pitch perception. Modern brain imaging techniques have suggested possible cortical locations for pitch mechanisms. This timely volume presents recent findings, while emphasizing their relation to the discoveries of the past. It brings together insights from several different methodological areas: physiology, psychophysics, comparative, imaging, etc., in addressing a single scientific problem. Pitch perception can be regarded as one of the main problems of hearing.
Piecewise-smooth Dynamical Systems : Theory and Applications
The primary purpose of this book is to present a coherent framework for understanding the dynamics of piecewise-smooth and hybrid systems. An informal introduction asserts the ubiquity of such models with examples drawn from mechanics, electronics, control theory and physiology. The main thrust is to classify complex behavior via bifurcation theory in a systematic yet applicable way. The key concept is that of a discontinuity-induced bifurcation, which generalizes diverse phenomena such as grazing, border-collision, sliding, chattering and the period-adding route to chaos. The results are presented in an informal style and illustrated with copious examples, both theoretical and experimental.
Pharmacovigilance in the European Union : Practical Implementation across Member States
Presents the results of an in-depth comparative study assessing the implementation of the EU Pharmacovigilance Directive in six EU Member States. By going beyond legal transposition and instead focusing on practical implementation, this study aims to close a gap in EU compliance research. Based on qualitative interviews with relevant actors in Germany, Poland, Portugal, France, Finland and the UK, the authors identify perceived challenges and best-practices, issue recommendations, and thereby contribute to a better understanding of the factors that incentivize or impede the practical implementation of EU law at the national level.
Pharmacological Mechanisms in Alzheimers Therapeutics
Alzheimer’s is the most common dementia in the elderly. The need for effective therapy of dementia is greater than ever, but there is not, as yet, a drug therapy which can stop or reverse the clinical consequences. The book should be of interest to medical professionals and basic scientists alike since it provides ideas about current trends in Alzheimer’s therapeutics to the general public.
Pharmaceutical biotechnology : fundamentals and applications
This introductory text explains both the basic science, production, quality, dosage forms, administration, economic and regulatory aspects and the clinical applications of biotechnology-derived pharmaceuticals. It serves as a complete one-stop source for undergraduate/graduate pharmacists and pharmaceutical science students. An additional important audience are pharmaceutical scientists in industry and academia, particularly those who have not received formal training in pharmaceutical biotechnology and are inexperienced in this field. The rapid growth and advances in the field made it necessary to revise this textbook in order to continue providing up-to-date information and introduce readers to cutting edge knowledge and technology of this field.
Pharmaceutical biotechnology : fundamentals and applications
Explains both basic science and applications of pharmaceutical biotechnology / Complete one-stop source for students and professionals / Explains both the basic science and the applications of biotechnology derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those who did not receive formal training in this field. Pharmaceutical Biotechnology: Fundamentals and Applications, Fifth Edition completely updates the previous edition, and includes additional coverage on newer approaches such as oligonucleotides, mi/siRNA, gene therapy and advanced therapeutics.
Perspectives on Operations Research : Essays in Honor of Klaus Neumann
Operations Research, the science of better, is a discipline that permanently produces and applies advanced analytical techniques to help make better decisions and to solve problems. This volume presents state-of-the-art models, algorithms, and applications of quantitative methods in management and economics. The papers have been contributed by disciples, colleagues, scientific companions, and friends of Klaus Neumann on the occasion of his emeritation.
Person-Centered Health Records : Toward HealthePeople
The book consists of three important sections. Section I addresses how the new person-centered system will change the way individuals care for their own health, giving them health records that accompany them throughout their lives, across the full range of experiences that affect their health. Section II lays out considerations involved in building new systems, including the need to address human factors such as control and ownership and the difficulties involved in relearning and learning to function in changed workflow environments. The third section focuses on approaches to transformation including focuses on delivering change, open source health systems, critical standards convergence, and person-centered systems now in place outside the United States. Chapter highlights include Clinical Impact, Human Factors, Health Security and Privacy, Critical Standards Convergence, and much more.
Peritoneal Carcinomatosis : a Multidisciplinary Approach
This book will be of interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC, as well as for basic and translational scientists active in the field of locoregional cancer spread. Numerous illustrations aid the reader throughout in the many facets of this disease.
Periodontology and dental implantology
Addresses the role of the oral healthcare provider in interprofessional communication in the systemic management of autoimmune bullous disease-associated conditions. A study involving chemically modified tetracyclines and host modulation with nonsurgical and surgical periodontal therapy, including postoperative pain management, is presented here. Therapeutic strategies of stem cell application in bone tissue engineering and the potential of platelet-rich fibrin-sourced growth factors in periodontal procedures to enhance wound healing and regeneration are also proposed. Supportive implant maintenance and regenerative processes are explored. Management of the endoperiodontal lesion is also discussed (note: the recent periodontal classification has not been referenced here). The book explores the best transdisciplinary practices for the management of special healthcare needs patients.
Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules
This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification.
Peer-Led Team Learning : Evaluation, Dissemination, and Institutionalization of a College Level Initiative
"Peer-Led Team Learning (PLTL) is one of the success stories resulting from the National Science Foundation's investment in educational innovation. Gafney and Varma-Nelson provide a coherent, tour-de-force look at the in-depth research that has been carried out, not only to understand the effect of PLTL on student learning, but also to understand the nature of the pedagogical method itself. This monograph is a jam-packed, one-stop destination for anyone who wants to learn what it means to understand a widespread pedagogical development in post-secondary science education."
Pediatric Surgery
Represents a leading international reference on the surgical management of diseases of infants and children. The editors have assembled experts from all five continents. Its up-to-date analysis of current practice provides comprehensive details on both surgical techniques and pre- and postoperative management. This atlas is an invaluable referene for pediatric surgeons and for general surgeons with a special interest in pediatric surgery.
Paul Rudolph : The Florida Houses
Paul Rudolph: The Florida Houses reveals all of Rudolph’s early residential work. With Rudolph’s personal essays and renderings, duotone photographs by Ezra Stoller and Joseph Molitor, and insightful text by Joseph King and Christopher Domin, this compelling new book conveys the lightness, timelessness, strength, materiality, and transcendency of Rudolph’s work
Pattern Recognition ; 29th DAGM Symposium, Heidelberg, Germany, September 12-14, 2007, Proceedings
Contains sections on image filtering, restoration and segmentation, shape analysis and representation, and recognition. This book also covers categorization and detection, computer vision and image retrieval, machine learning and statistical data analysis, biomedical data analysis, motion analysis and tracking, and pose recognition.
Pattern Language for Game Design
Builds on the revolutionary work of architect Christopher Alexander to show students, teachers, and game development professionals how to derive best practices in all aspects of game design. Using a series of practical, rigorous exercises, designers can observe and analyze the failures and successes of the games they know and love to find the deep patterns that underlie good design. From an in-depth look at Alexander's work, to a critique of pattern theory in various fields, to a new approach that will challenge your knowledge and put it to work, this book seeks to transform how we look at building the interactive experiences that shape us
Past and Present Water Column Anoxia
Contains papers partly based on presentations by 60 scientists attending a NATO Advanced Research Workshop on Past and Present Water Column Anoxia in Sevastopol, Ukraine. They address the entire range of oxygen-deficient conditions and reflect the complexity of the issues governing the formation and persistence of such conditions.
Particles and Nuclei : An Introduction to the Physical Concepts
This well-established textbook gives a uniform and unique presentation of both nuclear and particle physics. Analysis, Part 1, is devoted to disentangling the substructure of matter. This part shows that experiments designed to uncover the substructures of nuclei and nucleons have a similar conceptual basis, and lead to the present picture of all matter being built out of a small number of elementary building blocks and a small number of fundamental interactions. Synthesis, Part 2, shows how the elementary particles may be combined to build hadrons and nuclei. The fundamental interactions responsible for the forces in all systems become less and less evident in increasingly complex systems.
Particles and Nuclei : An Introduction to the Physical Concepts
To cope with modern developments, especially in nuclear physics research, this textbook presents nuclear and particle physics from a unifying point of view. The first part, Analysis, is devoted to disentangling the substructure of matter. The second part, Synthesis, shows how the elementary particles may be combined to build hadrons and nuclei.
Particle penetration and radiation effects : General aspects and stopping of swift point charges
This book, which has evolved from the author’s lectures at the University of Copenhagen and the University of Southern Denmark, draws on his experience as an active researcher in the interaction of charged particles with matter over more than forty years. The emphasis is on the theoretical description of fundamental phenomena, and much attention has been given to classic topics such as: Rutherford scattering; the theory of particle stopping as developed by Bohr, Bethe, Bloch and Lindhard; the statistical description of energy loss as developed by Bohr, Bothe, Williams and Landau; and numerous more recent developments. An attempt has been made to provide at least one complete derivation of a theoretical description for all central aspects. It is intended that this volume will satisfy a long-standing need for a textbook suitable for introductory courses on interactions of charged particles with matter for students of physics, chemistry and related fields at the graduate and postgraduate level. In order to make it useful for researchers in materials science, electrical engineering, medical technique and other application areas in science and engineering.
