الصفحة 56
الصفحة 56
Biophysical Aspects of Transmembrane Signaling
Transmembrane signaling is one of the most significant cell biological events in the life and death of cells in general and lymphocytes in particular. Until recently biochemists and biophysicists were not accustomed to thinking of these processes from the side of a high number of complex biochemical events and an equally high number of physical changes at molecular and cellular levels at the same time. Both types of researchers were convinced that their findings are the most decisive, having higher importance than the findings of the other scientist population. Both casts were wrong. Life, even at cellular level, has a number of interacting physical and biochemical mechanisms, which finally build up the creation of an "excited" cell that will respond to particular signals from the outer or inner world.
BioPaceMaking
The development of a bio-engineered pacemaker is of substantial clinical and also scientific interest because it promises to overcome several limitations of electronic pacemakers. Moreover it may answer the longstanding question of whether the complex structure of the sinus node is indeed a prerequisite for reliable pacemaking, or simpler structures might work as well. This book gives an overview of the current state-of-the-art of creating a bio-engineered pacemaker. It shows the approaches to develop of genetic and cell-based engineering methods suitable to implement them with safety and stability. It also illuminates the problems that need to be solved before bio-pacemaking can be considered for clinical use.
Bioorganometallic Chemistry
Bioorganometallic Chemistry has become a mature area of science and is comprehensively covered by leading experts in this book. Naturally occuring bioorganometallic complexes, such as vitamin B12 and recently discovered iron and nickel hydrogenases, including a possible role of the latter in the geochemical theory of the origin of life, are considered.
Biomimicry for Optimization, Control, and Automation
In this book, we focus onhowtousebiomimicryof the functionaloperationofthe “hardwareandso- ware” of biological systems for the development of optimization algorithms and feedbackcontrolsystemsthatextendourcapabilitiestoimplementsophisticated levels of automation. The primary focus is not on the modeling, emulation, or analysis of some biological system. The focus is on using “bio-inspiration” to inject new ideas, techniques, and perspective into the engineering of complex automation systems. There are many biological processes that, at some level of abstraction, can berepresentedasoptimizationprocesses,manyofwhichhaveasa basicpurpose automatic control, decision making, or automation.
Biomimetics for architecture & design : Nature - analogies - technology
Provides the readers with a timely guide to the application of biomimetic principles in architecture and engineering design. As a result of a combined effort by two internationally recognized authorities, the biologist Werner Nachtigall and the architect Göran Pohl, the book describes the principles which can be used to compare nature and technology, and at the same time it presents detailed explanations and examples showing how biology can be used as a source of inspiration and “translated” in building and architectural solutions (biomimicry). Even though nature cannot be directly copied, the living world can provide architects and engineers with a wealth of analogues and inspirations for their own creative designs. But how can analysis of natural entities give rise to advanced and sustainable design? By reporting on the latest bionic design methods and using extensive artwork, the book guides readers through the field of nature-inspired architecture, offering an extraordinary resource for professional architects, engineers, designers and urban planners, as well as for university teachers, researchers and students.
Biology and mechanics of blood flows ; Part I : Biology
Biology and Mechanics of Blood Flows presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part I of this two-volume sequence, Biology, addresses the nanoscopic and microscopic scales. The nanoscale corresponds to the scale of biochemical reaction cascades involved in cell adaptation to mechanical stresses among other stimuli. The microscale is the scale of stress-induced tissue remodeling associated with acute or chronic loadings. The cardiovascular system, like any physiological system, has a complicated three-dimensional structure and composition. Its time dependent behavior is regulated, and this complex system has many components.
Biologics, biosimilars, and biobetters : An introduction for pharmacists, physicians and other health practitioners
Explains what pharmacists need to discuss the equivalence, efficacy, safety, and risks of biosimilars with physicians, health practitioners, and patients about Guides regulators on pragmatic approaches to dealing with these drugs in the context of rapidly evolving scientific and clinical evidence Balances scientific information on complex drugs with practical information, such as a checklist for pharmacists
Bio-inspired computing and communication ; 1st Workshop on Bio-inspired design of networks, BIOWIRE 2007 Cambridge, UK, April 2-5, 2007 Revised Selected Papers
The book constitutes the thoroughly refereed post-workshop proceedings of the First Workshop on Bio-Inspired Design of Networks, BIOWIRE 2007, held in Cambridge, UK, in April 2007.
Bio-inspired computational intelligence and applications ; International conference on life system modeling, and simulation, LSMS 2007, Shanghai, China, September 14-17, 2007. Proceedings
It covers both micro and macro c- ponents ranging from cells, tissues and organs across to organisms and ecologic niches. These interact and evolve to produce an overall complex system whose beh- ior is difficult to comprehend and predict.The arrival of the 21st century has been marked by a resurgence of research interest both in arriving at a systems-level und- standing of biology and in applying such knowledge in complex real-world appli- tions. Consequently, computational methods and intelligence in systems, biology, as well as bio-inspired computational intelligence, have emerged as key drivers for new computational methods. For this reason papers dealing with theory, techniques and real-world applications relating to these two themes were especially solicited.
Bioinformatics research and applications : 4th International Symposium, ISBRA 2008, Atlanta, GA, USA, May 6-9, 2008. Proceedings
This book constitutes the refereed proceedings of the Fourth International Symposium on Bioinformatics Research and Applications, ISBRA 2008, held in Atlanta, GA, USA in May 2008.
Bioinformatics drug discovery
Quantitative tools are becoming increasingly important in order to understand complex cascade of signal transduction events, pathways or biochemical reactions. The book showcases how computational techniques and algorithms are applied to biological data analysis, interpretation, and modelling. It covers applications in drug design and discovery, immune systems, phylogenetic analysis and protein structures.
Bioinformatics : Problem Solving Paradigms
This book highlights basic paradigms of problem analysis and algorithm design in the context of core bioinformatics problems. Mathematically demanding themes are put across to the reader by properly chosen representations with the aid of lots of illustrations.
Biofuels and sustainability : Holistic perspectives for policy-making
This open access book presents a comprehensive analysis of biofuel use strategies from an interdisciplinary perspective using sustainability science. This interdisciplinary perspective (social science-natural science) means that the strategies and policy options proposed will have significant impacts on the economy and society alike. Biofuels are expected to contribute to reducing greenhouse gas emissions, revitalizing economies in agricultural communities and alleviating poverty. However, despite these anticipated benefits, international organizations such as the FAO, OECD and UN have published reports expressing concerns that biofuel promotion may lead to deforestation, water pollution and water shortages. The impacts of biofuel use are extensive, cross-sectoral and complex, and as such, comprehensive analyses are required in order to assess the extent to which biofuels can contribute to sustainable societies.
Big data-enabled internet of things
Covers analytical techniques for handling the huge amount of data generated by the Internet of Things, from architectures and platforms to security and privacy issues, applications, and challenges as well as future directions. The fields of Big Data and the Internet of Things (IoT) have seen tremendous advances, developments, and growth in recent years. The IoT is the inter-networking of connected smart devices, buildings, vehicles and other items which are embedded with electronics, software, sensors and actuators, and network connectivity that enable these objects to collect and exchange data. The IoT produces a lot of data. Big data describes very large and complex data sets that traditional data processing application software is inadequate to deal with, and the use of analytical methods to extract value from data. This edited book covers analytical techniques for handling the huge amount of data generated by the Internet of Things, from architectures and platforms to security and privacy issues, applications, and challenges as well as future directions.
Big Data Recommender Systems ; Vol.2 : Application Paradigms
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools. First designed to generate personalized recommendations to users in the 90s, recommender systems apply knowledge discovery techniques to users’ data to suggest information, products, and services that best match their preferences. In recent decades, we have seen an exponential increase in the volumes of data, which has introduced many new challenges. recommender systems. Volume 2 covers a broad range of application paradigms for recommender systems over 22 chapters
Big Data Recommender Systems ; Vol.1 : Algorithms, Architectures, Big Data, Security and Trust
Combines experimental and theoretical research on big data recommender systems to help computer scientists develop new concepts and methodologies for complex applications. It includes original scientific contributions in the form of theoretical foundations, comparative analysis, surveys, case studies, techniques and tools.
Big Data : Conceptual Analysis and Applications
The book is devoted to the analysis of big data in order to extract from these data hidden patterns necessary for making decisions about the rational behavior of complex systems with the different nature that generate this data. To solve these problems, a group of new methods and tools is used, based on the self-organization of computational processes, the use of crisp and fuzzy cluster analysis methods, hybrid neural-fuzzy networks, and others. The book solves various practical problems. In particular, for the tasks of 3D image recognition and automatic speech recognition large-scale neural networks with applications for Deep Learning systems were used.
Beyond the apparent Banality of the mathematics classroom
New research in mathematics education deals with the complexity of the mathematics’ classroom. The classroom teaching situation constitutes a pertinent unit of analysis for research into the ternary didactic relationship which binds teachers, students and mathematical knowledge. The classroom is considered as a complex didactic system, which offers the researcher an opportunity to gauge the boundaries of the freedom that is left with regard to choices about the knowledge to be taught and the ways of organizing the students’ learning, while giveing rise to the study of interrelations between three main elements of the teaching process the: mathematical content to be taught and learned, management of the various time dimensions, and activity of the teacher who prepares and manages the class, to the benefit of the students' knowledge and the teachers' own experience.
Between Necessity and Probability : Searching for the Definition and Origin of Life
This study investigates the major theories of the origins of life in light of modern research with the aim of distinguishing between the necessary and the optional and between deterministic and random influences in the emergence of what we call ‘life.’ Life is treated as a cosmic phenomenon whose emergence and driving force should be viewed independently from its Earth-bound natural history. The author synthesizes all the fundamental life-related developments in a comprehensive scenario, and makes the argument that understanding life in its broadest context requires a material-independent perspective that identifies its essential fingerprints.
Benign anorectal diseases : Diagnosis with endoanal and endorectal ultrasound and new treatment options
New three-dimensional endoanal and endorectal ultrasonographic and magnetic resonance imaging techniques have given better insight into the complex anatomy of the pelvic floor and its pathologic modification in benign anorectal diseases. Obstetrical events leading to fecal incontinence in females, the relationship between fistulous tracks and the sphincter complex, and mechanisms of obstructed defecation syndrome can now be accurately evaluated, which is of fundamental importance for decision making.
