الصفحة 5
الصفحة 5
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Dendritic Cells in Clinics

Great advances have taken place in basic research and the clinical usefulness of dendritic cells (DCs). It has now been clearly established, for instance, that these cells play a crucial role in immune responses against infectious diseases and cancers. Antigen-presenting DCs are widely distributed in the body and regulate both immunity and immune tolerance. Experimental studies have provided important insights into DCs and how they can be used for treating animal models of various diseases that occur in humans. The role of these cells in pathogenesis and the treatment of human diseases is elaborately set forth in this valuable book. Researchers in the field are optimistic that DCs, already in use for treating patients with cancers, soon can be used therapeutically for patients with chronic infections, autoimmune diseases, and allergic manifestations. This volume provides a working definition of DCs and also explains the phenotypes and functions of DCs so that these can be readily understood not only by clinicians but by immunologists, researchers, and students as well.

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Defect-Oriented Testing for Nano-Metric CMOS VLSI Circuits

Failures of nano-metric technologies owing to defects and shrinking process tolerances give rise to significant challenges for IC testing. As the variation of fundamental parameters such as channel length, threshold voltage, thin oxide thickness and interconnect dimensions goes well beyond acceptable limits, new test methodologies and a deeper insight into the physics of defect-fault mappings are needed. In Defect-Oriented Testing for Nano-Metric CMOS VLSI Circuits state of the art of defect-oriented testing is presented from both a theoretical approach as well as from a practical point of view. Step-by-step handling of defect modeling, defect-oriented testing, yield modeling and its usage in common economics practices enables deeper understanding of concepts.

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Current Concepts in Autoimmunity and Chronic Inflammation

The ethiopathologies of autoimmune diseases are complex. A broad variety of cell types and gene products are involved. This book explores clinical and experimental evidence suggesting that the importance of an individual factor changes during the course of the disease.

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Computer safety, reliability, and security ; 39th International Conference, SAFECOMP 2020, Lisbon, Portugal, September 16–18, 2020, Proceedings

This book constitutes the proceedings of the 39th International Conference on Computer Safety, Reliability and Security, SAFECOMP 2020, held in Lisbon, Portugal, in September 2020.* The 27 full and 2 short papers included in this volume were carefully reviewed and selected from 116 submissions. They were organized in topical sections named: safety cases and argumentation; formal verification and analysis; security modelling and methods; assurance of learning-enabled systems; practical experience and tools; threat analysis and risk mitigation; cyber-physical systems security; and fault injection and fault tolerance.

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Computational intelligence for agent-based systems

In these last years the digital technology explosion has spawned so many new lifestyle models that the boundaries between "real" and "digital" are fiercely debated. This scenario has deeply changed the viewpoint about computer applications: computers become smaller, cheapest and hugely distributed in wired or unwired networks, applications become so flexible and intelligent as to tailor its communication facilities in order to increase the usability of the system. Such data-intensive, unstructured spaces featured by minimal or no centralized control flow, present a challenge for traditional methods of analysis, design and integration of advanced, distributed and intelligent computer systems. Within this challenge, an important role is played by two important research areas : Fuzzy Technology, thanks to its ability to exploit the tolerance for imprecision to achieve tractability and Agent Technology, thanks to its nature to employ agent-wise communities to carry out complex goals by means of smart interaction, cooperation, and pro-activeness.

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CMOS Multi-Channel Single-Chip Receivers for Multi-Gigabit Optical Data Communications

Focuses on optical communications for short and very short distance applications and discusses the monolithic integration of optical receivers with processing elements in standard CMOS technologies. CMOS Multi-Channel Single-Chip Receivers for Multi-Gigabit Optical Data Communications provides the reader with the necessary background knowledge to fully understand the trade-offs in short-distance communication receiver design and presents the key issues to be addressed in the development of such receivers in CMOS technologies. Moreover, novel design approaches are presented. A system-level design methodology allows for the impact analysis of different block specifications and system-wide design optimization. Statistical models are used for design space exploration in the scope of jitter tolerance analysis of clock recovery circuits.

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Massively Multi-Agent Technology ; AAMAS Workshops, MMAS 2006, LSMAS 2006, and CCMMS 2007 Hakodate, Japan, May 9, 2006 Honolulu, HI, USA, May 15, 2007 Selected and Revised Papers

This book constitutes the thoroughly refereed post-workshop proceedings of the joint AAMAS 2006 International Workshops on Massively Multi-Agent Systems, MMAS 2006, and on Large scale Multi-Agent Systems, LSMAS 2006, held in Hakodate, Japan, in May 2006, and of the International Workshop on Coordination and Control in Massively Multi-Agent Systems, CCMMS 2007, held in Honolulu, HI, USA, in May 2007 as associated event of AAMAS 2007.

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Languages, Methodologies and Development Tools for Multi-Agent Systems ; 1st International Workshop, LADS 2007, Durham, UK, September 4-6, 2007. Revised Selected Papers

Constitutes the thoroughly refereed post-workshop proceedings of the First International Workshop on Languages, Methodologies and Development Tools for Multi-Agent Systems, LADS 2007, held in Durham, UK, in September 2007. The workshop was part of MALLOW 2007, a federation of workshops on Multi-Agent Logics, Languages, and Organizations.

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Composition of embedded systems : Scientific and industrial issues ; 13th Monterey Workshop 2006 Paris, France, October 16-18, 2006 Revised Selected Papers

This book discussed a range of challenges in embedded systems design that require further major advances in software and systems composition technology. The papers are organized in topical sections on model driven develo.

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Biosaline Agriculture and Salinity Tolerance in Plants

This volume focuses on reclamation, management, and utilization of salt-affected soils, their sustainable use, and evaluation of plants inhabiting naturally occurring saline habitats. It is of interest to scientists and students as well as to agricultural institutions and farmers and will undoubtedly raise the scientific community's awareness of, and interest in salinity issues.

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Biosaline Agriculture and High Salinity Tolerance

this book reviews the current state of knowledge in biosaline agriculture and high salinity tolerance in plants. It mainly focuses on the biotic approach to economically utilize the stress-prone areas by growing resistant plants.This volume comprises three sections: physiology and biochemistry, ecology, and molecular biology. Thus, a systematic approach has been adopted to uncover plant responses to various ecological factors at physiological and molecular levels.

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Autonomic networking ; 1st International IFIP TC6 Conference, AN 2006, Paris, France, September 27-29, 2006, Proceedings

The autonomic communication paradigm has been defined mainly through the Autonomic Communications Forum (ACF) and particularly as follows: Autonomic communication is centered on selfware – an innovative approach to perform known and emerging tasks of a network control plane, both end-to-end and middle box communication-based. Selfware assures the capacity to evolve; however, it requires generic network instrumentation. Selfware principles and technologies borrow largely from well-established research on distributed systems, fault tolerance among others, from emerging research on non-conventional networking (multihop ad hoc, sensor, peer-to-peer, group communication, etc.

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Autonomic and Trusted Computing ; 4th International Conference, ATC 2007, Hong Kong, China, July 11-13, 2007, Proceedings

To cope with the growing and ubiquitous complexity, autonomic computing (AC) focuses on se- manageable computing and communication systems that exhibit self-awareness, self-configuration, self-optimization, self-healing, self-protection and other self-x operations to the maximum extenteven without human interventionor guidance. Organiccomputing(OC)additionally emphasizes natural-analogueconceptslike self-organization and controlled emergence. Any autonomic ororganic system must be trus tworthy to avoid the risk of l- ing control and to retain confidence that the system will not fail. Trust and/or distrust relationships on the Internet and in pervasive infrastructures are key factors to enable dynamic interaction and cooperation of various users, systems and services. Trusted/trustworthy computing (TC) aims at making computing and communication systems as well as services available, predictable, traceable, controllable, assessable, sustainable, dependable, persist-able, security/privacy protect-able, etc.

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Automotive software - connected services in mobile networks ; 1st Automotive software workshop, ASWSD 2004, San Diego, CA, USA, January 10-12, 2004, Revised Selected Papers

Software development for the automotive domain is currently subject to a silent revolution. On the one hand, software has become the enabling technology for almost all safety-critical and comfort functions o?ered to the customer. A total of 90 % of all innovations in automotive systems are directly or indirectly - abled by software. the following list highlights three of the corresponding challenges: First, the dependencies between safety-critical and comfort functions are rapidly increasing;a simple example is the interplay of airbag controland power seat control in the case of an accident. Careful analysis and design of these dependencies are necessary to yield correct software solutions. Second, advances in wired and wireless networking infrastructures enable - terconnection between cars and backend service providers .

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Automated technology for verification and analysis ; 6th International Symposium, ATVA 2008, Seoul, Korea, October 20-23, 2008. Proceedings

This book constitutes the refereed proceedings of the 6th International Symposium on Automated Technology for Verification and Analysis, ATVA 2008, held in Seoul, Korea, in October 2008.

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Aspirin tablet film coated with famotidine

Focuses on enhancing the gastrointestinal tolerance of aspirin tablets by coating them with famotidine, a histamine-2 receptor antagonist known for its ability to reduce stomach acid production. The project aims to investigate the potential of famotidine coating in mitigating the gastric side effects commonly associated with aspirin usage, such as gastric irritation and ulcers. Through a series of in vitro studies, the project will evaluate the effectiveness of famotidine-coated aspirin tablets in reducing gastric mucosal damage and improving overall gastrointestinal safety.

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Architecting dependable systems IV

As software systems become ubiquitous, the issues of dependability become more and more crucial. Given that solutions to these issues must be considered from the very beginning of the design process, it is reasonable that dependability is addressed at the architectural level. It also contains sections on architectural description languages, architectural components and patterns, architecting distributed systems, and architectural assurances for dependability.

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Allergy in Practice

This book reflects the rich personal experience of a German allergist with international training and reputation, who is active in immunology and allergy research and practice for almost 30 years. In this book, not only IgE-mediated allergic reactions are covered but all other kinds of allergies such as atopic eczema, contact dermatitis, drug eruptions, anaphylaxis and food allergies are equally represented as well as psychosomatic aspects and problems of environmental intolerances.

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Algorithms for Sensor and Ad Hoc Networks : Advanced Lectures

Thousands of mini computers (comparable to a stick of chewing gum in size), equipped with sensors, are deployed in some terrain or other. After activation the sensors form a self-organized network and provide data, for example about a forthcoming earthquake. The trend towards wireless communication increasingly affects electronic devices in almost every sphere of life. Conventional wireless networks rely on infrastructure such as base stations; mobile devices interact with these base stations in a client/server fashion. In contrast, current research is focusing on networks that are completely unstructured, but are nevertheless able to communicate (via several hops) with each other, despite the low coverage of their antennas. Such systems are called sensor or ad hoc networks, depending on the point of view and the application. Wireless ad hoc and sensor networks have gained an incredible research momentum. Computer scientists and engineers of all flavors are embracing the area. Sensor networks have been adopted by researchers in many fields: from hardware technology to operating systems, from antenna design to databases, from information theory to networking, from graph theory to computational geometry.

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Adverse Food Reaction

Adverse food reaction is a broad term indicating a link between an ingestion of a food and an abnormal response. Adverse reactions to foods, aside from those considered toxic, are caused by a particular individual intolerance towards commonly tolerated foods. Intolerance derived from an immunological mechanism is referred to as Food Allergy, the non-immunological form is called Food Intolerance. IgE-mediated food allergy is the most common and dangerous type of adverse food reaction. It is initiated by an impairment of normal Oral Tolerance to food in predisposed individuals (atopic). Food allergy produces respiratory, gastrointestinal, cutaneous and cardiovascular symptoms but often generalized, life-threatening symptoms manifest at a rapid rate-anaphylactic shock.

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