تحسين النتائح
ترتيب حسب
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الصفحة 5
الصفحة 5
Bee products : Chemical and biological properties
Presents an updated discussion on the chemical composition and biological properties of the main bee products, which until now have been presented separately in different editions This book scoops out studies about bee products most used in marketing and in traditional medicine such as honey, royal jelly, propolis, bee pollen and bee venom Discusses chemical composition and biological function of the different bee products on topics such as nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections Bee products are rich in several essential nutrients and non essential nutrients, as sugars, minerals, proteins, free amino acids, vitamins, enzymes and polyphenols, that seem to be closely related to their biological functions. The effects of these products in nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections are discussed.
Basis and Treatment of Cardiac Arrhythmias
Incorporating the information related to mechanisms and treatment of cardiac arrhythmia, this book discusses genetics of arrhythmias, cell signalling molecules as potential therapeutic targets and trafficking to the membrane. These approaches and implementations of anti-arrhythmic therapy derive from many decades of research.
Ballistic Trauma : A Practical Guide
Ballistic Trauma: A Practical Guide provides a concise guide to the clinical and operational issues surrounding the management of the ballistic casualty. The book crystallizes the knowledge and experience accrued by those dealing with ballistic trauma on a regular basis and extends this to those who have to manage these patients on an occasional basis only.
Bacterial signal transduction : Networks and drug targets
Interactions among different TCSs enable one system to respond to multiple signals, which is important for bacteria to minutely adjust themselves to complex environmental changes. Such interactions are found or predicted in various bacteria in this book. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been brought to light. Reports on these develop› ments have been put together in this book, Bacterial Signal Transduction: Networks andDrug Targets. This book Offers an incentive for graduate students, academic scientists, and researchers in the pharmaceutical industry to further elucidate the TCS networks and apply them in the search for novel drugs.
Axonal branching and recovery of coordinated muscle activity after transsection of the facial nerve in adult rats
Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this "post-paralytic syndrome" is the misdirected reinnervation of targets
Autoimmune Diseases of the Skin : Pathogenesis, Diagnosis, Management
The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The second edition has been extended by chapters on autoimmune pigmentary disorders (vitiligo), hairloss (alopecia areata) and cutaneous symptoms of rheumatic disorders.
Auriculothérapie : Acupuncture auriculaire = Auriculotherapy : Auricular acupuncture
The auricle is a privileged place to observe and treat patients reflexively. It is endowed with both a particularly rich innervation, and brief connections with the higher nervous centers. It constitutes both a reading pavilion, to observe information coming from the organs and nerve endings of the skin, and a control pavilion to help correct abnormal information. It is a lookout post, placed bypassing the brainstem, on the path connecting the organs and the brain. It thus allows a fair control and an effective intervention. In this medical treatise on Auriculotherapy, historical and scientific data, medical explanations and bibliographical references are presented.
Artificial intelligence in drug design
Looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future.
Aquaculture microbiology
Details techniques involved to study aquatic pathogens that cause infections, especially in fish. Chapters guide readers through a wide range of basic and advanced methods, viral and fungal pathogens, probiotic bacteria, treatment of pathogens using seaweed extract, medicinal plant extracts, and actinomycetes.
Applied Peritoneal Dialysis : Improving Patient Outcomes
This book offers a comprehensive guide to peritoneal dialysis (PD). Home dialysis, and more specifically PD, is growing in popularity in the US. By conservative estimates, experts suggest that 45 percent of dialysis patients in the US can be on home dialysis. However, the current penetration rate is only 10 percent. This is changing with an expected major increase in the next 5 years. One of the reasons for the low uptake is that many nephrologists lack comfort and confidence in using PD as a dialysis modality.
Applications of nanotechnology in drug discovery and delivery
Presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials
Apoptotic pathways as targets for novel therapies in cancer and other diseases
The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients.
Anxiety and Anxiolytic Drugs
The present volume gives a comprehensive overview on the current state of basic and clinical research on Anxiety and Anxiolytic Drugs. Using newly developed methods and techniques researchers are now beginning to understand the molecular mechanisms of anxiety, anxiety disorders and their treatment. In parallel, new drug targets have been generated and the first clinical studies with new compounds have been started. In 20 chapters written by numerous experts in the field comprehensive information on all relevant topics is provided.
Anti-viral metabolites from medicinal plants
Covers general concepts of anti-viral metabolites, classifications, ethnopharmacology, chemistry, clinical and preclinical studies focusing on different medicinal plants against various types of viral infections. Various plants have been used in medicine since ancient times and are known for their strong therapeutic effects. The book will describe potential antiviral properties of medicinal plants against a diverse group of viruses, and provide an insight to the potential plants possess for broad-spectrum antiviral effects against emerging viral infections.The book aims to target a broad audience including virologists, molecular biologist, microbiologist and scientists working with natural products as well as researchers, students, healthcare experts involved in pharmaceutical and medical field.
Antioxidants effects in health : The bright and the dark side ; 1st ed.
Examines the role that antioxidants play in a variety of health and disease situations. The book discusses antioxidants’ historical evolution, their oxidative stress, and contains a detailed approach of 1) endogenous antioxidants, including endogenous sources, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; 2) synthetic antioxidants, including sources, chemistry, bioavailability, legal status, mechanisms of action, beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies; and 3) natural antioxidants, including sources, chemistry, bioavailability, mechanisms of action, possible prooxidant activity; beneficial and detrimental effects on health, in vitro evidence, animal studies and clinical studies. Throughout the boo, the relationship of antioxidants with different beneficial and detrimental effects are examined, and the current controversies and future perspectives are addressed and explored. Antioxidants Effects in Health: The Bright and the Dark Side evaluates the current scientific evidence on antioxidant topics, focusing on endogenous antioxidants, naturally occurring antioxidants and synthetic antioxidants. It will be a helpful resource for pharmaceutical scientists, health professionals, those studying natural chemistry, phytochemistry, pharmacognosy, natural product synthesis, and experts in formulation of herbal and natural pharmaceuticals.
Antioxidants and Cardiovascular Disease
Antioxidants and Cardiovascular Disease, Second Edition addresses a complex but very timely and fascinating problem in cardiovascular medicine. It is written by recognized experts in the fields of atherosclerosis and antioxidants. It should be of interest not only to academicians but also to practicing physicians.
Antibiotics : Methods and protocols
Provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, as well as methods for the analysis and detection of microbial responses and adaptation strategies. Antibiotics: Methods and Protocols, Second Edition, guides readers through updated and entirely new chapters on production and design, mode of action, and response and resistance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Antibiotic pharmacokinetic : Pharmacodynamic considerations in the critically Ill
Provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.
Antiangiogenic Agents in Cancer Therapy
Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer. Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.
Antarctic ecosystems : Environmental contamination, climate change, and human impact
This volume provides an overview of climate change data, its effects on the structure and functioning of Antarctic ecosystems, and the occurrence and cycling of persistent contaminants. It discusses the unique physico-chemical characteristics of the Antarctic environment, ecophysiological adaptations of terrestrial and marine organisms, the transfer of contaminants in pelagic and neritic food chains and the possible consequences for animals at higher trophic levels.
