الصفحة 5
الصفحة 5
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Auriculothérapie : Acupuncture auriculaire = Auriculotherapy : Auricular acupuncture

The auricle is a privileged place to observe and treat patients reflexively. It is endowed with both a particularly rich innervation, and brief connections with the higher nervous centers. It constitutes both a reading pavilion, to observe information coming from the organs and nerve endings of the skin, and a control pavilion to help correct abnormal information. It is a lookout post, placed bypassing the brainstem, on the path connecting the organs and the brain. It thus allows a fair control and an effective intervention. In this medical treatise on Auriculotherapy, historical and scientific data, medical explanations and bibliographical references are presented.

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Atrial Fibrillation : From bench to bedside

This book is a single source that provides a multi-perspective look at and approach to Atrial Fibrillation. Because Atrial Fibrillation is so prevalent and affects all areas of medicine, the information in this book will be useful to cardiologists, cardiac surgeons, researchers, and all those in the medical field.

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Ascochyta blights of grain legumes

Ascochyta blights consistently affect large areas of grain legume production (pea, lentil, chickpea and faba bean) in all countries where they are cultivated. These diseases are capable of causing large yield losses under conducive environmental conditions. This book considers the state of the art by taking a comparative approach of Ascochyta blight diseases of cool season food and feed legumes. Topics considered are pathogen diversity, legume genetics and breeding, and integrated disease management.

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Artificial oxygen carrier; its frontline

This volume of the Keio University International Symposia for Life Sciences and Medicine contains the proceedings of the 13th symposium held under the sponsorship of the Keio University Medical Science Fund. The fund was est- lished by the generous donation of the late Dr. Mitsunada Sakaguchi. The Keio University International Symposia for Life Sciences and Medicine constitute one of the core activities sponsored by the fund,of which the objective is to contribute to the international community by developing human resources, promoting scienti?c knowledge, and encouraging mutual exchange. Each year, the Committee of the International Symposia for Life Sciences and Medicine selects the most signi?cant symposium topics from applications received from the Keio medical community. The publication of the proce- ings is intended to publicize and distribute the information arising from the lively discussions of the most exciting and current issues presented during the symposium.

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Aquaponics Food Production Systems : Combined Aquaculture and Hydroponic Production Technologies for the Future

This book, written by world experts in aquaponics and related technologies, provides the authoritative and comprehensive overview of the key aquaculture and hydroponic and other integrated systems, socio-economic and environmental aspects. Aquaponic systems, which combine aquaculture and vegetable food production offer alternative technology solutions for a world that is increasingly under stress through population growth, urbanisation, water shortages, land and soil degradation, environmental pollution, world hunger and climate change.

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Applications of Plant Metabolic Engineering

Written by leading international experts in the field of plant metabolic engineering, this book discusses, mainly, applications of plant metabolic engineering. Metabolic engineering, which is part of second generation biotechnology, has made several contributions at basic level as well as at conceptualising products ever since its emergence in the early 1980s. Applications resulting from metabolic engineering are expected to play a very important role in future for plant breeding, e.g. for improved resistance or improved traits concerning health promoting constituents, and production of fine chemicals such as medicines, flavors and fragrances.

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Aortic dissection and related syndromes

Aortic dissection affects approximately two in ten thousand individuals and can be fatal. This state-of-the-art publication is a result of the combined efforts of participants from the International Registry of Aortic Dissection (IRAD). The book has been divided into sections. Each chapter provides a succinct overview of the current clinical literature and incorporates illustrations for further explanation.

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Anxiety disorders : A pocket guide for primary care

In Anxiety Disorders: A Pocket Guide for Primary Care, distinguished clinicians combine over a century of experience into concise, practical information and techniques for the diagnosis, evaluation, and effective management of psychiatric disorders.

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Antisense RNA Design, Delivery, and Analysis

This volume gathers a variety of models, delivery systems, and approaches that can be used to assess RNA technology for exploiting antisense as a therapeutic intervention. Beginning with a section on the design of antisense technology and their delivery, the book continues by covering model systems developed to evaluate efficacy, both in vivo and in vitro, as well as methods to evaluate preclinically the toxicity associated with these new potential drugs, and intellectual property considerations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Antioxidants

Highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

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Antifouling Compounds

Increasing awareness of the deleterious effects of toxic components in antifouling coatings has raised interest in the potential for nontoxic alternatives. This book examines how marine organisms from bacteria to invertebrates and plants use chemicals to communicate and defend themselves. Chemicals that prevent colonisation of living surfaces are particularly pertinent to antifouling technology and may inspire new solutions. The challenge is to identify such compounds, identify the means for sustainable production and incorporate them into coatings to give long-term antifouling efficacy.

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Antidiabetic plants for drug discovery pharmacology, secondary metabolite profiling, and ingredients with insulin mimetic activity

Takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives. Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as fl avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs. Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology.

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Antibiotic Policies : Fighting Resistance

This book addresses many of the key issues taxing our society and hospitals in an era of epidemic resistance and shortage of new antibiotics. Written by internationally renowned experts in the field, this volume will provide practical advice and inform control strategies for the most urgent of problems related to antibiotic resistance epidemic for years to come. Antibiotic Policies: Fighting Resistance is an ideal volume for health professionals with an interest in this field.

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Antibiotic pharmacokinetic : Pharmacodynamic considerations in the critically Ill

Provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.

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Anthropologies of Global Maternal and Reproductive Health : From Policy Spaces to Sites of Practice

This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors – both internationally respected anthropologists and new voices – demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals’ and lay people’s intimate encounters with policy.

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Anterior knee pain and patellar instability

This multidisciplinary book reviews the diagnosis and management of anterior knee pain and patellar instability in an eminently clinical and practical manner. The book reviews the therapeutic alternatives, both surgical and non-surgical, emphasizing the considerable importance of minimal intervention and non-surgical methods. Similarly, anterior knee pain following ACL reconstruction is covered in detail.

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Anorectal Malformations in Children : Embryology, Diagnosis, Surgical Treatment, Follow-up

The book assembles many new aspects in the broad field of anorectal and genitourinary malformations. Special attention is given to the new surgical techniques posterior sagittal anorectal plasty (PSARP), urogenital sinue advancement, and laparoscopy. The results of an international workshop of 26 international authorities on congenital malformations of the organs of the pelvis and perineum are presented. The new classification proposed at the Krickenberg Conference will enable future studies comparing the types and the results of treatment of anorectal malformations.

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Animal Models of T Cell-Mediated Skin Diseases

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.

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Anestetici locali in analgesia ostetrica : Il modello MLAC : dalla teoria alla pratica clinica = Local anesthetics in obstetric analgesia : The MLAC model : from theory to clinical practice

This monograph contains a detailed description of the MLAC method and its applications and an extensive and updated review of the most significant studies on the subject and their clinical implications. Studies that use the up-down sequential allocation method have made a significant contribution to clarifying numerous questions that the anesthetist asks himself every day in the delivery room and today rightly flank traditional studies representing, together with them, the primary source of updating and knowledge that are indispensable for good clinical practice based not only on experience but also on evidence and scientific rationale.

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Alternative Splicing and Disease

Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.

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