الصفحة 5
الصفحة 5
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Polymer Synthesis : Theory and Practice : Fundamentals, Methods, Experiments

The first English edition of this book was pubUshed in 1971 with the late Prof. Dr. Werner Kern as coauthor. In 1997, for the preparation of the third edition, Prof. Dr. Helmut Ritter joined the team of authors and in 2001 Prof. Dr. Brigitte Voit and Prof. Dr. Matthias Rehahn complemented this team. The change in authors has not altered the basic concept of this 4th edition: again we were not aimed at compiling a comprehensive collection of recipes. In­ stead, we attempted to reach a broader description of the general methods and techniques for the synthesis, modification, and characterization of macromo- cules, supplemented by 105 selected and detailed experiments and by sufficient theoretical treatment so that no additional textbook be needed in order to under­ stand the experiments. In addition to the preparative aspects we have also tried to give the reader an impression of the relation of chemical structure and mor­ phology of polymers to their properties, as well as of areas of their application.

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Polycomb group proteins : Methods and protocols

Explores the latest technologies used in the Polycomb Group of proteins field and helps scientists--working on PcG proteins--investigate all functions of PcG proteins in diverse cellular contexts. The chapters in this book cover topics such the distribution of histone marks by CUT&Tag in Drosophila embryos; Co-IP in mammalian cells; replication timing of gene loci in different cell cycle phases; STORM and electronmicroscopy and relative data analysis; and polycomb mediated epigenetic modification in spheroids.

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Physicians cancer chemotherapy : Drug manual

Completely revised and updated for 2024, the Physicians' Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens-both on- and off-label-for the treatment of all the major cancers.

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Periodontology at a glance

Provides readers with an easy-to-use tool to assimilate the key information about periodontics by illustrating each topic with a double-page spread that encapsulates essential knowledge. Clear diagrams and clinical pictures are accompanied by succinct text, providing a highly visual format to facilitate ease of learning. Suggestions for further reading are provided selectively where appropriate, and the authors present a useful distillation of the salient research literature. covers: Anatomy of the periodontium A etiology, diagnosis and classification of periodontal diseases Surgical and non-surgical therapiesPatient management Risk factors, including systemic disease

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Peptidomics : Methods and strategies

Explores essential techniques and newly emerged applications used in the expanding field of peptidomics. The opening chapters describe sample preparation and basic techniques. Subsequent chapters delve into quantitative peptidomics, bioinformatics, deep learning approaches, non-human model organisms, and peptide toxins. The last section includes multiple chapters on applications of peptidomics for human clinical specimens. Written for the highly successful Methods in Molecular Biology series, chapters include overviews and introductions to their respective topics, lists of the necessary materials, reagents, and instrumentation, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Peptide antibodies : Methods and protocols

Explores current methods for the production and use of peptide antibodies. The book delves into various aspects of peptide synthesis and analysis, peptide-carrier conjugation, epitope and paratope prediction and identification, as well as improved assays and other uses of peptide antibodies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective chapters, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Pavement Management for Airports, Roads, and Parking Lots

Emphasizing sound, cost-effective management rather than emergency repairs, this comprehensive volume offers practical guidelines on evaluating and managing pavements for airports, municipalities, and commercial real estate firms. Extensive appendices serve as field manuals for identifying all types of pavement distress and their causes, and hundreds of photographs facilitate accurate pavement evaluation.

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Palliative Care : Handbuch für Pflege und Begleitung = Palliative Care : Handbook for Care and Support

The "Palliative Care" manual is aimed at all professional caregivers in palliative work areas - whether outpatient or inpatient. Palliative care is a holistic care concept for patients who are at an advanced stage of an incurable disease. The active and comprehensive treatment, care and support of the chronically ill and dying is a great challenge for everyone involved. This practical book contains all the essential aspects of palliative care. It conveys the basics of professional care as well as specific specialist knowledge for all areas and professional fields of palliative care. In this way, caregivers can safely face the complex problems of nursing practice! . The content is very suitable for participants in the additional qualification "Palliative Care".

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Paediatric Imaging Manual

Imaging of Newborns, Infants, Children and Adolescents Children and adolescents are not simply small adults; they suffer from different diseases and require different treatments. The same is true where imaging is concerned. The diagnostic strategies – using identical diagnostic instruments – are different; the care prior to, during, and following the examination differs from that of adults. Because the number of Centers for Pediatric Radiology is small, students as well as pediatricians and general radiologists lack training in pediatric radiology and are often not sufficiently aware of these differences.

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Oxford Handbook of Clinical Dentistry ; 7th ed.

It balances a pragmatic approach alongside evidence-based clinical knowledge, guidelines, and protocols. It details how to take a history and perform an examination, moving on to discussing preventive and community dentistry, paediatric dentistry, and orthodontics. It thoroughly examines the subject of restorative dentistry through periodontology, tooth repair, tooth replacement, endodontics, and dental implants. It also explores oral surgery, oral medicine, and maxillofacial surgery

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Outlook 2007 : Beyond the Manual

This book goes farther faster into Outlooks advanced capabilities than other books. It shows you how to take control of the flow of information and time in your life and use Outlook to keep better tabs on it. It helps you take the thinking out of e-mail management, the tedium out of appointments and meeting scheduling, and the "rottenness" out of manual tasks.

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Oslo Manual on Select Topics of the Law of Armed Conflict : Rules and Commentary

Provides a valuable restatement of the current law of armed conflict regarding hostilities in a diverse range of contexts: outer space, cyber operations, remote and autonomous weapons, undersea systems and devices, submarine cables, civilians participating in unmanned operations, military objectives by nature, civilian airliners, destruction of property, surrender, search and rescue, humanitarian assistance, cultural property, the natural environment, and more.

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Oncologic and Cardiologic PET/CT-Diagnosis : An Interdisciplinary Atlas and Manual

Since 1999/2000 simultaneous imaging of anatomical features and metabolic activities using fused PET and CT images has complemented and in many cases even replaced what was originally done as separate analysis. – Is this a small revolution? – In fact, this new approach can be considered to be without a rival for imaging diagnosis. The complementary efforts of nuclear medicine physicians and radiologists have improved the diagnostic value of PET/CT scans. The successful use of PET/CT in the field of oncology has been documented world-wide, and in cardiology we can take advantage of the significant findings of PET diagnosis, particularly in the USA. New prospects are now available for paediatric oncology and molecular medicine.

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Obstetric life support manual

A comprehensive review in normal and abnormal pregnancy physiology, the most common etiologies of maternal medical emergencies, recognition of maternal deterioration and pending cardiopulmonary arrest, modifications to cardiopulmonary resuscitation in pregnant and postpartum patients, special procedures that can assist in diagnosing and treating maternal medical emergencies tailored to the setting (e.g., point-of-care ultrasound, resuscitative cesarean delivery, extracorporeal cardiopulmonary resuscitation), treatment of trauma/stroke in pregnancy, and postpartum maternal medical emergencies. There are streamlined algorithms and cognitive aids designed to improve a team’s ability to successfully implement techniques unique to treating maternal medical emergencies and car..

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Neutrophil : Methods and Protocols

Neutrophils, the most abundant white cells in humans, serve as the primary cellular defense against infection. This volume provides a concise set of protocols for assessing basic neutrophil functions and investigating specialized areas in neutrophil biology. Each of the protocols is written by leading researchers in the field and includes hints for success, as well as guidance for troubleshooting. Part I contains overviews of neutrophil biology, function, and disorders. Part II describes commonly used methods to isolate neutrophils from humans and other animal species. Part III details methods for investigating chemotaxis, transmigration, phagocytosis, and bactericidal activity. Part IV includes protocols that measure neutrophil apoptosis, calcium signal transduction, degranulation and detection of cytoplasmic granules, gene expression, transcription factors, and apoptosis. Part V provides multiple assays for measuring production of intracellular and/or extracellular reactive oxygen species, and a method that details use of the cell-free NADPH oxidase assay, an iconic assay for studies of the neutrophil NADPH oxidase. Part VI provides chapters that describe how to analyze formation and function of neutrophil extracellular traps.

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Neuroprotection : Method and protocols

Contains cutting-edge molecular biology methods on neuroprotective mechanisms and specific preclinical models of the CNS injury, iseases and planning translation. Chapters guide readers through neuropathology, neuroprotection, Alzheimer’s disease, amyotrophic lateral sclerosis, ALS, Huntington’s disease , multiple sclerosis, Parkinson’s disease, spinal cord injury, traumatic brain injury, and ischemic brain injury. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Neuronal cell death : Methods and protocols

Covers comprehensive methods on ways to assess structural and ultrastructural changes in the mitochondria, cytoskeleton, and microglia using state-of-the-art microscopy techniques including super-resolution imaging, electron microscopy, and ultra-high field MRI. The chapters in this book cover topics such as analysis of neurodegeneration in the post-mortem characterization of preclinical animal models, in vivo modeling in cell death in different model systems and brain organoids, single cell clonal analysis using Mosaic Analysis with Double Markers in genetic mouse models, and genome and proteomic methods for analysis of mRNA dynamics and quantitation of targeted peptides.

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Natural product experiments in drug discovery

Explores a wide range of evidence-based complementary medicine and various bio-analytical techniques used to define botanical products. Collecting recent work and current developments in the field of contemporary phytomedicine as well as their future possibilities in human health care, the book includes unique contributions in the form of chapters on phytomedicine and screening biological activities explained with diverse hyphenated techniques, as well as issues related to herbal medications, such as efficacy, adulteration, safety, toxicity, regulations, and drug delivery. Written for the Springer Protocols Handbooks series, chapters feature advice from experts on how to best conduct future experiments. Extensive and practical, Natural Product Experiments in Drug Discovery serves as an ideal reference for students, professors, and researchers in universities, R&D institutes, pharmaceutical and herbal enterprises, and health organizations.

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Mucins : Methods and protocols

Explores the latest advancements in mucin research. The chapters in this book are organized into 8 parts and cover a wide range of topics such as mucin extraction, isolation, physicochemical property analysis, and experimental methods. The chapters also discuss the origins of mucins in jellyfish, feces, saliva and salivary glands, bronchi, stomach, and cervical tract; organic synthesis of peptides glycosylated at specific sites; analysis of mucin gene expression and methylation-specific electrophoresis of genes; imaging of mucin networks by AFM; and experimental methods using supported molecular matrix electrophoresis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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Mosby's 2024 nursing drug reference

Makes it easy to find the most vital information on the drugs you administer most frequently. More than 5,000 drugs are profiled — including more than 25 new entries for drugs recently approved by the FDA. And no other drug guide places a higher emphasis on patient safety, with Black Box Warnings for dangerous adverse reactions, High Alerts for drugs with the greatest risk, and a focus on both common and life-threatening side effects. From nursing pharmacology expert Linda Skidmore-Roth, this perennial bestseller proves there is a difference in drug guides.

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